Amino acid dipepetide frequency for Aliidiomarina taiwanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.053AlaAla: 10.053 ± 0.13	0.958AlaCys: 0.958 ± 0.035	5.217AlaAsp: 5.217 ± 0.091	7.367AlaGlu: 7.367 ± 0.118	3.689AlaPhe: 3.689 ± 0.078	7.118AlaGly: 7.118 ± 0.095	2.092AlaHis: 2.092 ± 0.064	5.576AlaIle: 5.576 ± 0.094	4.004AlaLys: 4.004 ± 0.075	11.291AlaLeu: 11.291 ± 0.154	2.661AlaMet: 2.661 ± 0.063	3.249AlaAsn: 3.249 ± 0.078	3.728AlaPro: 3.728 ± 0.092	4.664AlaGln: 4.664 ± 0.081	5.156AlaArg: 5.156 ± 0.084	5.563AlaSer: 5.563 ± 0.085	4.95AlaThr: 4.95 ± 0.091	6.671AlaVal: 6.671 ± 0.094	1.277AlaTrp: 1.277 ± 0.045	2.58AlaTyr: 2.58 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	0.789CysAla: 0.789 ± 0.031	0.096CysCys: 0.096 ± 0.01	0.43CysAsp: 0.43 ± 0.026	0.519CysGlu: 0.519 ± 0.028	0.381CysPhe: 0.381 ± 0.025	0.701CysGly: 0.701 ± 0.031	0.267CysHis: 0.267 ± 0.021	0.486CysIle: 0.486 ± 0.024	0.29CysLys: 0.29 ± 0.018	0.8CysLeu: 0.8 ± 0.035	0.211CysMet: 0.211 ± 0.017	0.306CysAsn: 0.306 ± 0.02	0.421CysPro: 0.421 ± 0.024	0.41CysGln: 0.41 ± 0.026	0.446CysArg: 0.446 ± 0.026	0.564CysSer: 0.564 ± 0.027	0.438CysThr: 0.438 ± 0.024	0.642CysVal: 0.642 ± 0.03	0.111CysTrp: 0.111 ± 0.012	0.267CysTyr: 0.267 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.777AspAla: 4.777 ± 0.092	0.376AspCys: 0.376 ± 0.024	2.615AspAsp: 2.615 ± 0.061	3.534AspGlu: 3.534 ± 0.085	2.273AspPhe: 2.273 ± 0.059	3.372AspGly: 3.372 ± 0.089	1.062AspHis: 1.062 ± 0.037	3.648AspIle: 3.648 ± 0.07	2.263AspLys: 2.263 ± 0.063	4.762AspLeu: 4.762 ± 0.082	1.508AspMet: 1.508 ± 0.043	1.889AspAsn: 1.889 ± 0.048	2.1AspPro: 2.1 ± 0.051	1.76AspGln: 1.76 ± 0.046	2.333AspArg: 2.333 ± 0.056	2.718AspSer: 2.718 ± 0.059	2.958AspThr: 2.958 ± 0.059	3.793AspVal: 3.793 ± 0.075	0.821AspTrp: 0.821 ± 0.031	1.895AspTyr: 1.895 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.509GluAla: 6.509 ± 0.119	0.424GluCys: 0.424 ± 0.022	2.623GluAsp: 2.623 ± 0.067	4.275GluGlu: 4.275 ± 0.119	2.288GluPhe: 2.288 ± 0.06	4.205GluGly: 4.205 ± 0.096	1.99GluHis: 1.99 ± 0.054	3.046GluIle: 3.046 ± 0.074	2.909GluLys: 2.909 ± 0.07	7.614GluLeu: 7.614 ± 0.109	1.484GluMet: 1.484 ± 0.049	2.418GluAsn: 2.418 ± 0.053	2.554GluPro: 2.554 ± 0.068	4.956GluGln: 4.956 ± 0.106	4.673GluArg: 4.673 ± 0.084	3.496GluSer: 3.496 ± 0.07	3.188GluThr: 3.188 ± 0.065	4.552GluVal: 4.552 ± 0.08	0.786GluTrp: 0.786 ± 0.027	1.793GluTyr: 1.793 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	3.951PheAla: 3.951 ± 0.08	0.403PheCys: 0.403 ± 0.022	2.327PheAsp: 2.327 ± 0.058	2.431PheGlu: 2.431 ± 0.066	1.579PhePhe: 1.579 ± 0.056	3.059PheGly: 3.059 ± 0.074	0.942PheHis: 0.942 ± 0.032	2.493PheIle: 2.493 ± 0.064	1.548PheLys: 1.548 ± 0.045	3.451PheLeu: 3.451 ± 0.077	0.979PheMet: 0.979 ± 0.034	1.64PheAsn: 1.64 ± 0.049	1.515PhePro: 1.515 ± 0.045	1.426PheGln: 1.426 ± 0.043	1.814PheArg: 1.814 ± 0.053	2.892PheSer: 2.892 ± 0.062	2.371PheThr: 2.371 ± 0.05	2.932PheVal: 2.932 ± 0.073	0.547PheTrp: 0.547 ± 0.027	1.296PheTyr: 1.296 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	5.962GlyAla: 5.962 ± 0.099	0.721GlyCys: 0.721 ± 0.031	3.494GlyAsp: 3.494 ± 0.076	4.537GlyGlu: 4.537 ± 0.078	3.333GlyPhe: 3.333 ± 0.069	4.925GlyGly: 4.925 ± 0.111	1.768GlyHis: 1.768 ± 0.05	4.141GlyIle: 4.141 ± 0.086	3.286GlyLys: 3.286 ± 0.068	7.293GlyLeu: 7.293 ± 0.103	2.131GlyMet: 2.131 ± 0.055	2.317GlyAsn: 2.317 ± 0.067	2.158GlyPro: 2.158 ± 0.055	3.244GlyGln: 3.244 ± 0.071	3.736GlyArg: 3.736 ± 0.066	4.128GlySer: 4.128 ± 0.089	3.664GlyThr: 3.664 ± 0.071	5.782GlyVal: 5.782 ± 0.109	0.984GlyTrp: 0.984 ± 0.041	2.51GlyTyr: 2.51 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.291HisAla: 2.291 ± 0.068	0.306HisCys: 0.306 ± 0.022	1.189HisAsp: 1.189 ± 0.042	1.432HisGlu: 1.432 ± 0.042	1.15HisPhe: 1.15 ± 0.04	1.836HisGly: 1.836 ± 0.053	0.679HisHis: 0.679 ± 0.034	1.504HisIle: 1.504 ± 0.046	1.005HisLys: 1.005 ± 0.04	2.44HisLeu: 2.44 ± 0.064	0.59HisMet: 0.59 ± 0.029	0.831HisAsn: 0.831 ± 0.033	1.285HisPro: 1.285 ± 0.046	1.159HisGln: 1.159 ± 0.039	1.254HisArg: 1.254 ± 0.041	1.439HisSer: 1.439 ± 0.04	1.333HisThr: 1.333 ± 0.037	1.696HisVal: 1.696 ± 0.046	0.46HisTrp: 0.46 ± 0.022	0.937HisTyr: 0.937 ± 0.035	0.0HisXaa: 0.0 ± 0.0
Ile	5.808IleAla: 5.808 ± 0.097	0.497IleCys: 0.497 ± 0.025	3.338IleAsp: 3.338 ± 0.075	4.077IleGlu: 4.077 ± 0.076	1.735IlePhe: 1.735 ± 0.051	4.128IleGly: 4.128 ± 0.097	1.303IleHis: 1.303 ± 0.04	2.93IleIle: 2.93 ± 0.078	2.178IleLys: 2.178 ± 0.056	4.607IleLeu: 4.607 ± 0.085	1.216IleMet: 1.216 ± 0.045	2.145IleAsn: 2.145 ± 0.063	2.534IlePro: 2.534 ± 0.069	2.451IleGln: 2.451 ± 0.061	2.987IleArg: 2.987 ± 0.064	3.409IleSer: 3.409 ± 0.063	3.079IleThr: 3.079 ± 0.07	3.658IleVal: 3.658 ± 0.079	0.589IleTrp: 0.589 ± 0.029	1.452IleTyr: 1.452 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.244LysAla: 4.244 ± 0.091	0.226LysCys: 0.226 ± 0.018	1.941LysAsp: 1.941 ± 0.052	2.853LysGlu: 2.853 ± 0.068	1.137LysPhe: 1.137 ± 0.034	2.671LysGly: 2.671 ± 0.067	1.11LysHis: 1.11 ± 0.037	1.75LysIle: 1.75 ± 0.048	2.186LysLys: 2.186 ± 0.064	4.164LysLeu: 4.164 ± 0.073	0.955LysMet: 0.955 ± 0.037	1.525LysAsn: 1.525 ± 0.046	2.092LysPro: 2.092 ± 0.051	2.444LysGln: 2.444 ± 0.061	2.764LysArg: 2.764 ± 0.06	2.328LysSer: 2.328 ± 0.063	1.994LysThr: 1.994 ± 0.057	3.113LysVal: 3.113 ± 0.066	0.425LysTrp: 0.425 ± 0.026	1.044LysTyr: 1.044 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.549LeuAla: 11.549 ± 0.147	0.958LeuCys: 0.958 ± 0.036	5.335LeuAsp: 5.335 ± 0.085	6.534LeuGlu: 6.534 ± 0.091	4.059LeuPhe: 4.059 ± 0.088	7.354LeuGly: 7.354 ± 0.111	2.528LeuHis: 2.528 ± 0.058	5.298LeuIle: 5.298 ± 0.106	4.281LeuLys: 4.281 ± 0.086	11.089LeuLeu: 11.089 ± 0.169	2.616LeuMet: 2.616 ± 0.066	4.207LeuAsn: 4.207 ± 0.074	5.222LeuPro: 5.222 ± 0.091	4.939LeuGln: 4.939 ± 0.096	5.605LeuArg: 5.605 ± 0.093	7.091LeuSer: 7.091 ± 0.103	6.357LeuThr: 6.357 ± 0.095	7.383LeuVal: 7.383 ± 0.103	1.194LeuTrp: 1.194 ± 0.045	2.694LeuTyr: 2.694 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	2.68MetAla: 2.68 ± 0.066	0.17MetCys: 0.17 ± 0.015	1.13MetAsp: 1.13 ± 0.038	1.198MetGlu: 1.198 ± 0.041	0.896MetPhe: 0.896 ± 0.037	1.731MetGly: 1.731 ± 0.058	0.605MetHis: 0.605 ± 0.026	1.075MetIle: 1.075 ± 0.043	1.215MetLys: 1.215 ± 0.035	2.84MetLeu: 2.84 ± 0.063	0.609MetMet: 0.609 ± 0.03	1.018MetAsn: 1.018 ± 0.04	1.348MetPro: 1.348 ± 0.041	1.39MetGln: 1.39 ± 0.047	1.488MetArg: 1.488 ± 0.045	1.865MetSer: 1.865 ± 0.051	1.464MetThr: 1.464 ± 0.038	1.786MetVal: 1.786 ± 0.048	0.215MetTrp: 0.215 ± 0.016	0.564MetTyr: 0.564 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.319AsnAla: 3.319 ± 0.078	0.323AsnCys: 0.323 ± 0.023	1.885AsnAsp: 1.885 ± 0.045	2.363AsnGlu: 2.363 ± 0.059	1.395AsnPhe: 1.395 ± 0.046	2.471AsnGly: 2.471 ± 0.075	0.761AsnHis: 0.761 ± 0.029	2.187AsnIle: 2.187 ± 0.057	1.709AsnLys: 1.709 ± 0.05	3.455AsnLeu: 3.455 ± 0.063	1.007AsnMet: 1.007 ± 0.036	1.523AsnAsn: 1.523 ± 0.052	2.072AsnPro: 2.072 ± 0.055	1.637AsnGln: 1.637 ± 0.054	1.958AsnArg: 1.958 ± 0.056	2.046AsnSer: 2.046 ± 0.054	2.197AsnThr: 2.197 ± 0.053	2.301AsnVal: 2.301 ± 0.051	0.563AsnTrp: 0.563 ± 0.027	1.184AsnTyr: 1.184 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	3.995ProAla: 3.995 ± 0.076	0.319ProCys: 0.319 ± 0.02	2.461ProAsp: 2.461 ± 0.058	3.871ProGlu: 3.871 ± 0.083	1.779ProPhe: 1.779 ± 0.044	3.083ProGly: 3.083 ± 0.065	1.082ProHis: 1.082 ± 0.045	2.17ProIle: 2.17 ± 0.053	1.715ProLys: 1.715 ± 0.048	4.571ProLeu: 4.571 ± 0.083	1.125ProMet: 1.125 ± 0.041	1.751ProAsn: 1.751 ± 0.054	1.502ProPro: 1.502 ± 0.052	1.842ProGln: 1.842 ± 0.059	1.919ProArg: 1.919 ± 0.058	2.593ProSer: 2.593 ± 0.063	2.367ProThr: 2.367 ± 0.055	3.575ProVal: 3.575 ± 0.068	0.657ProTrp: 0.657 ± 0.032	1.289ProTyr: 1.289 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	5.81GlnAla: 5.81 ± 0.106	0.319GlnCys: 0.319 ± 0.021	1.855GlnAsp: 1.855 ± 0.049	3.002GlnGlu: 3.002 ± 0.069	1.552GlnPhe: 1.552 ± 0.043	3.618GlnGly: 3.618 ± 0.078	1.574GlnHis: 1.574 ± 0.049	1.919GlnIle: 1.919 ± 0.058	1.716GlnLys: 1.716 ± 0.052	5.922GlnLeu: 5.922 ± 0.116	0.993GlnMet: 0.993 ± 0.033	1.351GlnAsn: 1.351 ± 0.049	2.284GlnPro: 2.284 ± 0.061	4.137GlnGln: 4.137 ± 0.117	3.341GlnArg: 3.341 ± 0.085	2.624GlnSer: 2.624 ± 0.055	2.368GlnThr: 2.368 ± 0.049	4.284GlnVal: 4.284 ± 0.087	0.719GlnTrp: 0.719 ± 0.032	1.257GlnTyr: 1.257 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	4.616ArgAla: 4.616 ± 0.084	0.439ArgCys: 0.439 ± 0.024	2.768ArgAsp: 2.768 ± 0.065	3.723ArgGlu: 3.723 ± 0.083	2.536ArgPhe: 2.536 ± 0.063	3.28ArgGly: 3.28 ± 0.076	1.407ArgHis: 1.407 ± 0.038	3.555ArgIle: 3.555 ± 0.065	2.239ArgLys: 2.239 ± 0.053	6.271ArgLeu: 6.271 ± 0.099	1.512ArgMet: 1.512 ± 0.041	2.0ArgAsn: 2.0 ± 0.048	2.121ArgPro: 2.121 ± 0.045	2.715ArgGln: 2.715 ± 0.067	3.236ArgArg: 3.236 ± 0.07	3.176ArgSer: 3.176 ± 0.065	2.805ArgThr: 2.805 ± 0.07	4.198ArgVal: 4.198 ± 0.074	0.87ArgTrp: 0.87 ± 0.037	1.974ArgTyr: 1.974 ± 0.057	0.0ArgXaa: 0.0 ± 0.0
Ser	5.465SerAla: 5.465 ± 0.086	0.55SerCys: 0.55 ± 0.035	3.177SerAsp: 3.177 ± 0.079	3.704SerGlu: 3.704 ± 0.084	2.717SerPhe: 2.717 ± 0.062	4.581SerGly: 4.581 ± 0.081	1.409SerHis: 1.409 ± 0.045	3.373SerIle: 3.373 ± 0.065	2.458SerLys: 2.458 ± 0.052	6.628SerLeu: 6.628 ± 0.101	1.696SerMet: 1.696 ± 0.048	2.161SerAsn: 2.161 ± 0.054	2.569SerPro: 2.569 ± 0.055	2.9SerGln: 2.9 ± 0.063	3.205SerArg: 3.205 ± 0.067	3.866SerSer: 3.866 ± 0.083	3.05SerThr: 3.05 ± 0.066	4.194SerVal: 4.194 ± 0.076	0.814SerTrp: 0.814 ± 0.035	1.851SerTyr: 1.851 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	5.254ThrAla: 5.254 ± 0.081	0.436ThrCys: 0.436 ± 0.022	2.83ThrAsp: 2.83 ± 0.068	3.525ThrGlu: 3.525 ± 0.064	2.077ThrPhe: 2.077 ± 0.061	4.365ThrGly: 4.365 ± 0.08	1.331ThrHis: 1.331 ± 0.045	2.823ThrIle: 2.823 ± 0.052	1.806ThrLys: 1.806 ± 0.047	6.265ThrLeu: 6.265 ± 0.1	1.127ThrMet: 1.127 ± 0.034	1.786ThrAsn: 1.786 ± 0.052	3.08ThrPro: 3.08 ± 0.067	2.558ThrGln: 2.558 ± 0.068	2.75ThrArg: 2.75 ± 0.071	3.08ThrSer: 3.08 ± 0.07	2.925ThrThr: 2.925 ± 0.061	3.8ThrVal: 3.8 ± 0.073	0.708ThrTrp: 0.708 ± 0.03	1.483ThrTyr: 1.483 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	7.27ValAla: 7.27 ± 0.115	0.599ValCys: 0.599 ± 0.028	3.761ValAsp: 3.761 ± 0.076	4.646ValGlu: 4.646 ± 0.091	3.053ValPhe: 3.053 ± 0.067	4.701ValGly: 4.701 ± 0.093	1.68ValHis: 1.68 ± 0.046	4.099ValIle: 4.099 ± 0.087	2.739ValLys: 2.739 ± 0.064	7.68ValLeu: 7.68 ± 0.12	1.897ValMet: 1.897 ± 0.06	2.707ValAsn: 2.707 ± 0.057	3.237ValPro: 3.237 ± 0.071	3.101ValGln: 3.101 ± 0.059	4.087ValArg: 4.087 ± 0.081	4.834ValSer: 4.834 ± 0.076	4.388ValThr: 4.388 ± 0.07	5.725ValVal: 5.725 ± 0.112	0.894ValTrp: 0.894 ± 0.036	1.902ValTyr: 1.902 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	0.941TrpAla: 0.941 ± 0.033	0.124TrpCys: 0.124 ± 0.013	0.561TrpAsp: 0.561 ± 0.028	0.568TrpGlu: 0.568 ± 0.025	0.625TrpPhe: 0.625 ± 0.031	0.761TrpGly: 0.761 ± 0.035	0.446TrpHis: 0.446 ± 0.024	0.56TrpIle: 0.56 ± 0.027	0.333TrpLys: 0.333 ± 0.021	2.025TrpLeu: 2.025 ± 0.058	0.347TrpMet: 0.347 ± 0.02	0.414TrpAsn: 0.414 ± 0.025	0.554TrpPro: 0.554 ± 0.028	1.165TrpGln: 1.165 ± 0.046	0.928TrpArg: 0.928 ± 0.047	0.771TrpSer: 0.771 ± 0.033	0.469TrpThr: 0.469 ± 0.026	1.041TrpVal: 1.041 ± 0.044	0.211TrpTrp: 0.211 ± 0.019	0.441TrpTyr: 0.441 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.58TyrAla: 2.58 ± 0.067	0.334TyrCys: 0.334 ± 0.022	1.522TyrAsp: 1.522 ± 0.051	1.624TyrGlu: 1.624 ± 0.048	1.346TyrPhe: 1.346 ± 0.043	2.153TyrGly: 2.153 ± 0.057	0.777TyrHis: 0.777 ± 0.03	1.488TyrIle: 1.488 ± 0.046	1.084TyrLys: 1.084 ± 0.042	3.126TyrLeu: 3.126 ± 0.069	0.621TyrMet: 0.621 ± 0.027	1.117TyrAsn: 1.117 ± 0.046	1.289TyrPro: 1.289 ± 0.042	1.749TyrGln: 1.749 ± 0.045	1.76TyrArg: 1.76 ± 0.055	1.885TyrSer: 1.885 ± 0.048	1.642TyrThr: 1.642 ± 0.054	1.875TyrVal: 1.875 ± 0.048	0.441TyrTrp: 0.441 ± 0.024	0.946TyrTyr: 0.946 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2309 proteins (771387 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---