Amino acid dipepetide frequency for Mus musculus polyomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.824AlaAla: 6.824 ± 2.758
1.241AlaCys: 1.241 ± 0.769
2.481AlaAsp: 2.481 ± 0.786
6.824AlaGlu: 6.824 ± 0.845
2.481AlaPhe: 2.481 ± 1.409
5.583AlaGly: 5.583 ± 3.222
1.861AlaHis: 1.861 ± 0.74
4.342AlaIle: 4.342 ± 2.292
1.861AlaLys: 1.861 ± 1.075
8.065AlaLeu: 8.065 ± 2.369
1.861AlaMet: 1.861 ± 0.641
1.861AlaAsn: 1.861 ± 1.074
0.62AlaPro: 0.62 ± 0.5
3.722AlaGln: 3.722 ± 1.067
3.102AlaArg: 3.102 ± 1.309
5.583AlaSer: 5.583 ± 2.089
2.481AlaThr: 2.481 ± 1.096
3.102AlaVal: 3.102 ± 1.106
1.241AlaTrp: 1.241 ± 0.769
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.861CysAla: 1.861 ± 0.924
0.62CysCys: 0.62 ± 0.726
2.481CysAsp: 2.481 ± 1.537
0.0CysGlu: 0.0 ± 0.0
1.241CysPhe: 1.241 ± 0.868
0.62CysGly: 0.62 ± 0.5
0.0CysHis: 0.0 ± 0.0
0.62CysIle: 0.62 ± 0.726
4.342CysLys: 4.342 ± 2.551
2.481CysLeu: 2.481 ± 1.491
0.0CysMet: 0.0 ± 0.0
1.241CysAsn: 1.241 ± 0.548
0.0CysPro: 0.0 ± 0.0
0.62CysGln: 0.62 ± 0.501
0.62CysArg: 0.62 ± 0.5
0.62CysSer: 0.62 ± 0.501
1.861CysThr: 1.861 ± 1.503
1.241CysVal: 1.241 ± 0.769
0.62CysTrp: 0.62 ± 0.726
3.722CysTyr: 3.722 ± 2.211
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.62AspCys: 0.62 ± 0.726
0.0AspAsp: 0.0 ± 0.0
2.481AspGlu: 2.481 ± 0.99
3.102AspPhe: 3.102 ± 1.434
6.824AspGly: 6.824 ± 1.841
0.0AspHis: 0.0 ± 0.0
4.342AspIle: 4.342 ± 1.455
2.481AspLys: 2.481 ± 1.491
4.342AspLeu: 4.342 ± 1.441
0.62AspMet: 0.62 ± 0.5
2.481AspAsn: 2.481 ± 0.433
4.342AspPro: 4.342 ± 1.732
2.481AspGln: 2.481 ± 0.433
1.241AspArg: 1.241 ± 1.002
2.481AspSer: 2.481 ± 0.66
1.861AspThr: 1.861 ± 0.641
4.342AspVal: 4.342 ± 0.922
1.241AspTrp: 1.241 ± 0.756
1.861AspTyr: 1.861 ± 1.503
0.0AspXaa: 0.0 ± 0.0
Glu
4.342GluAla: 4.342 ± 2.687
2.481GluCys: 2.481 ± 0.99
3.722GluAsp: 3.722 ± 1.794
5.583GluGlu: 5.583 ± 1.467
0.0GluPhe: 0.0 ± 0.0
4.342GluGly: 4.342 ± 2.055
1.861GluHis: 1.861 ± 0.641
3.722GluIle: 3.722 ± 1.282
3.722GluLys: 3.722 ± 1.686
8.065GluLeu: 8.065 ± 1.292
1.241GluMet: 1.241 ± 0.756
3.722GluAsn: 3.722 ± 1.459
1.241GluPro: 1.241 ± 1.002
2.481GluGln: 2.481 ± 0.868
1.861GluArg: 1.861 ± 0.915
2.481GluSer: 2.481 ± 1.364
3.722GluThr: 3.722 ± 1.481
3.102GluVal: 3.102 ± 2.013
0.0GluTrp: 0.0 ± 0.0
1.861GluTyr: 1.861 ± 1.215
0.0GluXaa: 0.0 ± 0.0
Phe
1.861PheAla: 1.861 ± 1.503
2.481PheCys: 2.481 ± 1.491
0.0PheAsp: 0.0 ± 0.0
3.722PheGlu: 3.722 ± 1.715
1.241PhePhe: 1.241 ± 0.999
4.342PheGly: 4.342 ± 1.255
0.62PheHis: 0.62 ± 0.5
0.62PheIle: 0.62 ± 0.501
3.102PheLys: 3.102 ± 2.505
3.102PheLeu: 3.102 ± 0.763
1.861PheMet: 1.861 ± 0.924
0.0PheAsn: 0.0 ± 0.0
0.62PhePro: 0.62 ± 0.501
0.62PheGln: 0.62 ± 0.501
4.963PheArg: 4.963 ± 1.681
1.241PheSer: 1.241 ± 0.548
0.62PheThr: 0.62 ± 0.726
1.241PheVal: 1.241 ± 0.548
0.62PheTrp: 0.62 ± 0.5
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.203GlyAla: 6.203 ± 2.613
1.241GlyCys: 1.241 ± 1.002
1.241GlyAsp: 1.241 ± 0.868
5.583GlyGlu: 5.583 ± 1.549
1.861GlyPhe: 1.861 ± 0.74
7.444GlyGly: 7.444 ± 1.777
3.102GlyHis: 3.102 ± 0.802
8.685GlyIle: 8.685 ± 2.37
3.722GlyLys: 3.722 ± 1.404
5.583GlyLeu: 5.583 ± 1.336
0.62GlyMet: 0.62 ± 0.415
3.102GlyAsn: 3.102 ± 1.114
4.342GlyPro: 4.342 ± 1.115
2.481GlyGln: 2.481 ± 0.433
4.963GlyArg: 4.963 ± 1.914
7.444GlySer: 7.444 ± 2.723
2.481GlyThr: 2.481 ± 1.012
4.963GlyVal: 4.963 ± 0.989
0.0GlyTrp: 0.0 ± 0.0
2.481GlyTyr: 2.481 ± 1.121
0.0GlyXaa: 0.0 ± 0.0
His
2.481HisAla: 2.481 ± 0.888
1.241HisCys: 1.241 ± 0.769
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.62HisPhe: 0.62 ± 0.5
1.861HisGly: 1.861 ± 0.74
0.62HisHis: 0.62 ± 0.501
0.0HisIle: 0.0 ± 0.0
1.241HisLys: 1.241 ± 1.002
0.62HisLeu: 0.62 ± 0.5
1.241HisMet: 1.241 ± 0.769
2.481HisAsn: 2.481 ± 1.012
0.62HisPro: 0.62 ± 0.726
0.0HisGln: 0.0 ± 0.0
3.722HisArg: 3.722 ± 1.282
1.861HisSer: 1.861 ± 0.785
2.481HisThr: 2.481 ± 0.88
1.241HisVal: 1.241 ± 1.453
0.0HisTrp: 0.0 ± 0.0
2.481HisTyr: 2.481 ± 0.699
0.0HisXaa: 0.0 ± 0.0
Ile
7.444IleAla: 7.444 ± 3.784
1.241IleCys: 1.241 ± 1.002
1.861IleAsp: 1.861 ± 0.641
3.102IleGlu: 3.102 ± 1.229
2.481IlePhe: 2.481 ± 1.381
0.0IleGly: 0.0 ± 0.0
2.481IleHis: 2.481 ± 0.888
0.62IleIle: 0.62 ± 0.501
1.241IleLys: 1.241 ± 0.548
4.342IleLeu: 4.342 ± 0.922
0.62IleMet: 0.62 ± 0.501
4.342IleAsn: 4.342 ± 2.296
8.685IlePro: 8.685 ± 2.526
3.102IleGln: 3.102 ± 0.709
0.0IleArg: 0.0 ± 0.0
0.62IleSer: 0.62 ± 0.726
0.62IleThr: 0.62 ± 0.501
6.203IleVal: 6.203 ± 1.62
0.62IleTrp: 0.62 ± 0.501
0.62IleTyr: 0.62 ± 0.501
0.0IleXaa: 0.0 ± 0.0
Lys
4.963LysAla: 4.963 ± 1.398
1.861LysCys: 1.861 ± 1.075
3.722LysAsp: 3.722 ± 1.14
3.722LysGlu: 3.722 ± 1.404
0.62LysPhe: 0.62 ± 0.501
4.342LysGly: 4.342 ± 2.256
1.241LysHis: 1.241 ± 1.002
4.342LysIle: 4.342 ± 1.894
4.963LysLys: 4.963 ± 1.941
3.722LysLeu: 3.722 ± 1.404
1.241LysMet: 1.241 ± 0.755
4.342LysAsn: 4.342 ± 1.455
1.241LysPro: 1.241 ± 0.868
2.481LysGln: 2.481 ± 0.99
5.583LysArg: 5.583 ± 0.771
2.481LysSer: 2.481 ± 0.868
3.722LysThr: 3.722 ± 1.794
4.963LysVal: 4.963 ± 1.613
0.62LysTrp: 0.62 ± 0.726
1.241LysTyr: 1.241 ± 1.002
0.0LysXaa: 0.0 ± 0.0
Leu
2.481LeuAla: 2.481 ± 0.786
1.861LeuCys: 1.861 ± 0.922
4.963LeuAsp: 4.963 ± 2.081
6.203LeuGlu: 6.203 ± 2.547
3.102LeuPhe: 3.102 ± 1.862
6.203LeuGly: 6.203 ± 0.737
3.722LeuHis: 3.722 ± 2.106
4.342LeuIle: 4.342 ± 1.012
4.342LeuLys: 4.342 ± 1.567
13.027LeuLeu: 13.027 ± 2.816
1.861LeuMet: 1.861 ± 1.98
5.583LeuAsn: 5.583 ± 1.122
6.824LeuPro: 6.824 ± 2.056
6.203LeuGln: 6.203 ± 2.617
1.861LeuArg: 1.861 ± 1.075
6.203LeuSer: 6.203 ± 1.931
5.583LeuThr: 5.583 ± 1.94
3.722LeuVal: 3.722 ± 0.79
0.0LeuTrp: 0.0 ± 0.0
4.963LeuTyr: 4.963 ± 0.708
0.0LeuXaa: 0.0 ± 0.0
Met
1.861MetAla: 1.861 ± 0.915
1.241MetCys: 1.241 ± 1.002
1.241MetAsp: 1.241 ± 1.002
1.861MetGlu: 1.861 ± 1.215
0.0MetPhe: 0.0 ± 0.0
1.861MetGly: 1.861 ± 0.678
0.0MetHis: 0.0 ± 0.0
1.861MetIle: 1.861 ± 0.641
0.62MetLys: 0.62 ± 0.726
1.861MetLeu: 1.861 ± 0.641
0.0MetMet: 0.0 ± 0.0
1.861MetAsn: 1.861 ± 1.075
0.0MetPro: 0.0 ± 0.0
1.861MetGln: 1.861 ± 0.641
1.241MetArg: 1.241 ± 0.868
1.861MetSer: 1.861 ± 0.922
1.241MetThr: 1.241 ± 0.999
0.62MetVal: 0.62 ± 0.501
0.0MetTrp: 0.0 ± 0.0
1.241MetTyr: 1.241 ± 0.999
0.0MetXaa: 0.0 ± 0.0
Asn
1.861AsnAla: 1.861 ± 0.641
0.62AsnCys: 0.62 ± 0.5
3.722AsnAsp: 3.722 ± 0.986
0.62AsnGlu: 0.62 ± 0.5
0.62AsnPhe: 0.62 ± 0.501
2.481AsnGly: 2.481 ± 1.534
1.241AsnHis: 1.241 ± 0.999
1.861AsnIle: 1.861 ± 1.503
1.861AsnLys: 1.861 ± 1.075
4.963AsnLeu: 4.963 ± 1.333
0.62AsnMet: 0.62 ± 0.5
5.583AsnAsn: 5.583 ± 1.645
2.481AsnPro: 2.481 ± 0.433
2.481AsnGln: 2.481 ± 0.433
3.722AsnArg: 3.722 ± 1.103
4.342AsnSer: 4.342 ± 2.389
1.241AsnThr: 1.241 ± 0.785
8.685AsnVal: 8.685 ± 0.725
0.62AsnTrp: 0.62 ± 0.501
1.241AsnTyr: 1.241 ± 0.548
0.0AsnXaa: 0.0 ± 0.0
Pro
2.481ProAla: 2.481 ± 0.786
0.62ProCys: 0.62 ± 0.726
6.203ProAsp: 6.203 ± 1.563
1.861ProGlu: 1.861 ± 1.077
1.861ProPhe: 1.861 ± 0.641
3.102ProGly: 3.102 ± 0.709
0.0ProHis: 0.0 ± 0.0
2.481ProIle: 2.481 ± 0.433
8.065ProLys: 8.065 ± 1.519
4.342ProLeu: 4.342 ± 1.854
0.0ProMet: 0.0 ± 0.0
0.62ProAsn: 0.62 ± 0.5
2.481ProPro: 2.481 ± 1.096
0.62ProGln: 0.62 ± 0.5
4.342ProArg: 4.342 ± 1.465
4.342ProSer: 4.342 ± 2.138
1.861ProThr: 1.861 ± 0.924
4.963ProVal: 4.963 ± 0.892
0.0ProTrp: 0.0 ± 0.0
1.241ProTyr: 1.241 ± 0.548
0.0ProXaa: 0.0 ± 0.0
Gln
2.481GlnAla: 2.481 ± 0.786
0.62GlnCys: 0.62 ± 0.5
1.241GlnAsp: 1.241 ± 0.756
3.102GlnGlu: 3.102 ± 0.802
1.241GlnPhe: 1.241 ± 1.002
6.824GlnGly: 6.824 ± 1.848
1.861GlnHis: 1.861 ± 0.533
1.861GlnIle: 1.861 ± 0.641
3.722GlnLys: 3.722 ± 0.986
1.861GlnLeu: 1.861 ± 0.641
3.102GlnMet: 3.102 ± 0.49
0.62GlnAsn: 0.62 ± 0.5
0.62GlnPro: 0.62 ± 0.726
2.481GlnGln: 2.481 ± 0.786
3.722GlnArg: 3.722 ± 1.481
1.861GlnSer: 1.861 ± 0.641
0.0GlnThr: 0.0 ± 0.0
1.241GlnVal: 1.241 ± 0.548
1.861GlnTrp: 1.861 ± 0.915
1.241GlnTyr: 1.241 ± 0.756
0.0GlnXaa: 0.0 ± 0.0
Arg
4.342ArgAla: 4.342 ± 2.138
1.241ArgCys: 1.241 ± 0.868
2.481ArgAsp: 2.481 ± 0.88
3.722ArgGlu: 3.722 ± 1.103
2.481ArgPhe: 2.481 ± 1.096
0.62ArgGly: 0.62 ± 0.5
0.62ArgHis: 0.62 ± 0.501
3.102ArgIle: 3.102 ± 1.414
4.963ArgLys: 4.963 ± 1.776
5.583ArgLeu: 5.583 ± 1.344
1.861ArgMet: 1.861 ± 0.924
0.62ArgAsn: 0.62 ± 0.5
3.102ArgPro: 3.102 ± 0.574
0.62ArgGln: 0.62 ± 0.5
6.203ArgArg: 6.203 ± 3.779
4.963ArgSer: 4.963 ± 1.926
3.102ArgThr: 3.102 ± 1.309
4.963ArgVal: 4.963 ± 1.086
0.0ArgTrp: 0.0 ± 0.0
3.722ArgTyr: 3.722 ± 1.236
0.0ArgXaa: 0.0 ± 0.0
Ser
3.722SerAla: 3.722 ± 1.913
1.241SerCys: 1.241 ± 0.868
6.203SerAsp: 6.203 ± 2.617
4.342SerGlu: 4.342 ± 1.899
0.62SerPhe: 0.62 ± 0.501
7.444SerGly: 7.444 ± 2.323
0.0SerHis: 0.0 ± 0.0
1.861SerIle: 1.861 ± 0.533
2.481SerLys: 2.481 ± 0.699
6.824SerLeu: 6.824 ± 1.102
0.62SerMet: 0.62 ± 0.502
4.342SerAsn: 4.342 ± 1.105
3.102SerPro: 3.102 ± 2.013
1.861SerGln: 1.861 ± 0.785
3.722SerArg: 3.722 ± 0.636
3.722SerSer: 3.722 ± 1.864
4.342SerThr: 4.342 ± 1.465
3.722SerVal: 3.722 ± 0.652
1.241SerTrp: 1.241 ± 0.756
1.861SerTyr: 1.861 ± 1.074
0.0SerXaa: 0.0 ± 0.0
Thr
3.102ThrAla: 3.102 ± 0.958
1.861ThrCys: 1.861 ± 1.075
3.102ThrAsp: 3.102 ± 0.681
1.861ThrGlu: 1.861 ± 1.499
2.481ThrPhe: 2.481 ± 0.699
6.824ThrGly: 6.824 ± 2.056
0.0ThrHis: 0.0 ± 0.0
1.861ThrIle: 1.861 ± 0.924
1.861ThrLys: 1.861 ± 1.075
3.722ThrLeu: 3.722 ± 1.14
1.861ThrMet: 1.861 ± 0.922
1.861ThrAsn: 1.861 ± 0.74
3.722ThrPro: 3.722 ± 0.854
1.241ThrGln: 1.241 ± 0.548
1.861ThrArg: 1.861 ± 0.641
2.481ThrSer: 2.481 ± 1.04
3.102ThrThr: 3.102 ± 1.856
3.102ThrVal: 3.102 ± 0.574
0.0ThrTrp: 0.0 ± 0.0
2.481ThrTyr: 2.481 ± 1.096
0.0ThrXaa: 0.0 ± 0.0
Val
4.342ValAla: 4.342 ± 1.105
0.0ValCys: 0.0 ± 0.0
1.861ValAsp: 1.861 ± 0.641
3.722ValGlu: 3.722 ± 1.247
3.102ValPhe: 3.102 ± 1.948
5.583ValGly: 5.583 ± 2.606
2.481ValHis: 2.481 ± 1.469
1.861ValIle: 1.861 ± 0.74
2.481ValLys: 2.481 ± 1.096
7.444ValLeu: 7.444 ± 1.201
1.861ValMet: 1.861 ± 0.751
1.861ValAsn: 1.861 ± 0.904
6.824ValPro: 6.824 ± 0.41
6.203ValGln: 6.203 ± 2.153
2.481ValArg: 2.481 ± 0.433
5.583ValSer: 5.583 ± 1.746
5.583ValThr: 5.583 ± 2.501
8.685ValVal: 8.685 ± 1.329
1.241ValTrp: 1.241 ± 0.868
3.722ValTyr: 3.722 ± 0.986
0.0ValXaa: 0.0 ± 0.0
Trp
0.62TrpAla: 0.62 ± 0.5
0.0TrpCys: 0.0 ± 0.0
0.62TrpAsp: 0.62 ± 0.726
1.241TrpGlu: 1.241 ± 0.868
0.62TrpPhe: 0.62 ± 0.726
0.62TrpGly: 0.62 ± 0.726
0.62TrpHis: 0.62 ± 0.501
1.861TrpIle: 1.861 ± 0.74
1.241TrpLys: 1.241 ± 0.769
0.62TrpLeu: 0.62 ± 0.726
0.0TrpMet: 0.0 ± 0.0
0.62TrpAsn: 0.62 ± 0.5
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.62TrpArg: 0.62 ± 0.501
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.481TrpVal: 2.481 ± 1.511
0.0TrpTrp: 0.0 ± 0.0
0.62TrpTyr: 0.62 ± 0.501
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.861TyrAla: 1.861 ± 0.641
2.481TyrCys: 2.481 ± 1.537
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
3.102TyrPhe: 3.102 ± 0.709
0.62TyrGly: 0.62 ± 0.501
2.481TyrHis: 2.481 ± 0.699
0.0TyrIle: 0.0 ± 0.0
3.102TyrLys: 3.102 ± 1.142
3.102TyrLeu: 3.102 ± 1.948
0.62TyrMet: 0.62 ± 0.501
3.722TyrAsn: 3.722 ± 0.652
0.62TyrPro: 0.62 ± 0.5
0.0TyrGln: 0.0 ± 0.0
2.481TyrArg: 2.481 ± 0.888
3.102TyrSer: 3.102 ± 0.681
2.481TyrThr: 2.481 ± 0.433
4.342TyrVal: 4.342 ± 0.495
2.481TyrTrp: 2.481 ± 1.068
1.241TyrTyr: 1.241 ± 0.756
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1613 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski