Amino acid dipepetide frequency for Acinetobacter defluvii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.206AlaAla: 7.206 ± 0.109
0.948AlaCys: 0.948 ± 0.034
4.361AlaAsp: 4.361 ± 0.07
5.699AlaGlu: 5.699 ± 0.088
3.466AlaPhe: 3.466 ± 0.064
5.288AlaGly: 5.288 ± 0.095
1.822AlaHis: 1.822 ± 0.045
6.057AlaIle: 6.057 ± 0.093
5.326AlaLys: 5.326 ± 0.077
9.344AlaLeu: 9.344 ± 0.12
2.413AlaMet: 2.413 ± 0.052
3.47AlaAsn: 3.47 ± 0.066
2.772AlaPro: 2.772 ± 0.057
4.658AlaGln: 4.658 ± 0.074
3.325AlaArg: 3.325 ± 0.063
4.642AlaSer: 4.642 ± 0.073
4.492AlaThr: 4.492 ± 0.089
5.556AlaVal: 5.556 ± 0.075
1.047AlaTrp: 1.047 ± 0.035
2.669AlaTyr: 2.669 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.779CysAla: 0.779 ± 0.029
0.144CysCys: 0.144 ± 0.013
0.511CysAsp: 0.511 ± 0.022
0.56CysGlu: 0.56 ± 0.025
0.482CysPhe: 0.482 ± 0.022
0.785CysGly: 0.785 ± 0.033
0.289CysHis: 0.289 ± 0.017
0.674CysIle: 0.674 ± 0.025
0.439CysLys: 0.439 ± 0.02
1.031CysLeu: 1.031 ± 0.035
0.252CysMet: 0.252 ± 0.016
0.35CysAsn: 0.35 ± 0.018
0.443CysPro: 0.443 ± 0.023
0.402CysGln: 0.402 ± 0.025
0.41CysArg: 0.41 ± 0.02
0.617CysSer: 0.617 ± 0.026
0.466CysThr: 0.466 ± 0.024
0.722CysVal: 0.722 ± 0.027
0.109CysTrp: 0.109 ± 0.011
0.333CysTyr: 0.333 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
4.67AspAla: 4.67 ± 0.076
0.459AspCys: 0.459 ± 0.023
2.803AspAsp: 2.803 ± 0.061
3.681AspGlu: 3.681 ± 0.068
2.572AspPhe: 2.572 ± 0.057
3.116AspGly: 3.116 ± 0.068
1.295AspHis: 1.295 ± 0.04
3.726AspIle: 3.726 ± 0.061
2.677AspLys: 2.677 ± 0.056
5.804AspLeu: 5.804 ± 0.09
1.173AspMet: 1.173 ± 0.038
1.987AspAsn: 1.987 ± 0.049
2.158AspPro: 2.158 ± 0.056
2.929AspGln: 2.929 ± 0.06
2.356AspArg: 2.356 ± 0.054
2.579AspSer: 2.579 ± 0.056
2.443AspThr: 2.443 ± 0.059
3.759AspVal: 3.759 ± 0.072
0.846AspTrp: 0.846 ± 0.028
1.976AspTyr: 1.976 ± 0.047
0.0AspXaa: 0.0 ± 0.0
Glu
4.828GluAla: 4.828 ± 0.084
0.481GluCys: 0.481 ± 0.024
2.89GluAsp: 2.89 ± 0.059
3.287GluGlu: 3.287 ± 0.071
2.395GluPhe: 2.395 ± 0.057
3.111GluGly: 3.111 ± 0.073
1.712GluHis: 1.712 ± 0.046
4.53GluIle: 4.53 ± 0.066
4.539GluLys: 4.539 ± 0.075
6.229GluLeu: 6.229 ± 0.079
1.621GluMet: 1.621 ± 0.04
3.647GluAsn: 3.647 ± 0.066
1.792GluPro: 1.792 ± 0.078
4.25GluGln: 4.25 ± 0.076
2.956GluArg: 2.956 ± 0.058
3.065GluSer: 3.065 ± 0.058
2.939GluThr: 2.939 ± 0.054
3.785GluVal: 3.785 ± 0.065
0.786GluTrp: 0.786 ± 0.031
1.976GluTyr: 1.976 ± 0.041
0.0GluXaa: 0.0 ± 0.0
Phe
3.66PheAla: 3.66 ± 0.063
0.555PheCys: 0.555 ± 0.025
2.784PheAsp: 2.784 ± 0.054
2.737PheGlu: 2.737 ± 0.057
1.991PhePhe: 1.991 ± 0.048
3.063PheGly: 3.063 ± 0.059
0.914PheHis: 0.914 ± 0.029
3.153PheIle: 3.153 ± 0.055
2.86PheLys: 2.86 ± 0.06
3.807PheLeu: 3.807 ± 0.073
1.072PheMet: 1.072 ± 0.033
2.285PheAsn: 2.285 ± 0.052
1.51PhePro: 1.51 ± 0.041
1.713PheGln: 1.713 ± 0.043
1.416PheArg: 1.416 ± 0.041
3.112PheSer: 3.112 ± 0.057
2.157PheThr: 2.157 ± 0.05
2.649PheVal: 2.649 ± 0.052
0.558PheTrp: 0.558 ± 0.023
1.537PheTyr: 1.537 ± 0.042
0.0PheXaa: 0.0 ± 0.0
Gly
4.851GlyAla: 4.851 ± 0.089
0.776GlyCys: 0.776 ± 0.029
2.961GlyAsp: 2.961 ± 0.069
3.586GlyGlu: 3.586 ± 0.066
3.169GlyPhe: 3.169 ± 0.061
4.376GlyGly: 4.376 ± 0.107
1.463GlyHis: 1.463 ± 0.033
4.545GlyIle: 4.545 ± 0.069
3.686GlyLys: 3.686 ± 0.068
6.526GlyLeu: 6.526 ± 0.097
1.754GlyMet: 1.754 ± 0.041
2.454GlyAsn: 2.454 ± 0.071
1.276GlyPro: 1.276 ± 0.04
2.971GlyGln: 2.971 ± 0.059
2.771GlyArg: 2.771 ± 0.06
3.683GlySer: 3.683 ± 0.09
3.385GlyThr: 3.385 ± 0.099
4.53GlyVal: 4.53 ± 0.066
0.873GlyTrp: 0.873 ± 0.03
2.331GlyTyr: 2.331 ± 0.055
0.0GlyXaa: 0.0 ± 0.0
His
1.961HisAla: 1.961 ± 0.041
0.278HisCys: 0.278 ± 0.019
1.228HisAsp: 1.228 ± 0.037
1.27HisGlu: 1.27 ± 0.031
1.252HisPhe: 1.252 ± 0.036
1.527HisGly: 1.527 ± 0.038
0.786HisHis: 0.786 ± 0.034
1.662HisIle: 1.662 ± 0.038
1.029HisLys: 1.029 ± 0.034
2.554HisLeu: 2.554 ± 0.055
0.532HisMet: 0.532 ± 0.02
0.858HisAsn: 0.858 ± 0.027
1.254HisPro: 1.254 ± 0.037
1.344HisGln: 1.344 ± 0.041
1.031HisArg: 1.031 ± 0.031
1.335HisSer: 1.335 ± 0.04
1.165HisThr: 1.165 ± 0.033
1.49HisVal: 1.49 ± 0.04
0.351HisTrp: 0.351 ± 0.019
0.956HisTyr: 0.956 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
6.434IleAla: 6.434 ± 0.092
0.746IleCys: 0.746 ± 0.025
4.259IleAsp: 4.259 ± 0.065
4.885IleGlu: 4.885 ± 0.07
2.937IlePhe: 2.937 ± 0.061
4.629IleGly: 4.629 ± 0.08
1.582IleHis: 1.582 ± 0.035
4.175IleIle: 4.175 ± 0.078
3.65IleLys: 3.65 ± 0.06
6.584IleLeu: 6.584 ± 0.09
1.42IleMet: 1.42 ± 0.044
3.152IleAsn: 3.152 ± 0.061
2.87IlePro: 2.87 ± 0.053
3.864IleGln: 3.864 ± 0.071
2.868IleArg: 2.868 ± 0.051
4.605IleSer: 4.605 ± 0.076
3.563IleThr: 3.563 ± 0.079
4.228IleVal: 4.228 ± 0.068
0.706IleTrp: 0.706 ± 0.028
2.236IleTyr: 2.236 ± 0.048
0.0IleXaa: 0.0 ± 0.0
Lys
5.186LysAla: 5.186 ± 0.084
0.375LysCys: 0.375 ± 0.019
3.283LysAsp: 3.283 ± 0.081
3.327LysGlu: 3.327 ± 0.065
2.253LysPhe: 2.253 ± 0.046
3.215LysGly: 3.215 ± 0.064
1.336LysHis: 1.336 ± 0.038
4.237LysIle: 4.237 ± 0.074
3.974LysLys: 3.974 ± 0.074
5.698LysLeu: 5.698 ± 0.083
1.614LysMet: 1.614 ± 0.037
3.442LysAsn: 3.442 ± 0.061
2.352LysPro: 2.352 ± 0.046
3.522LysGln: 3.522 ± 0.06
2.573LysArg: 2.573 ± 0.055
3.433LysSer: 3.433 ± 0.062
3.626LysThr: 3.626 ± 0.071
4.097LysVal: 4.097 ± 0.069
0.66LysTrp: 0.66 ± 0.022
1.96LysTyr: 1.96 ± 0.048
0.0LysXaa: 0.0 ± 0.0
Leu
9.046LeuAla: 9.046 ± 0.115
1.073LeuCys: 1.073 ± 0.03
5.823LeuAsp: 5.823 ± 0.085
6.052LeuGlu: 6.052 ± 0.091
4.151LeuPhe: 4.151 ± 0.081
6.688LeuGly: 6.688 ± 0.095
2.07LeuHis: 2.07 ± 0.042
6.775LeuIle: 6.775 ± 0.089
7.074LeuLys: 7.074 ± 0.089
9.434LeuLeu: 9.434 ± 0.137
2.604LeuMet: 2.604 ± 0.054
5.744LeuAsn: 5.744 ± 0.078
4.329LeuPro: 4.329 ± 0.069
4.5LeuGln: 4.5 ± 0.08
4.011LeuArg: 4.011 ± 0.068
7.085LeuSer: 7.085 ± 0.092
5.561LeuThr: 5.561 ± 0.073
6.196LeuVal: 6.196 ± 0.089
1.123LeuTrp: 1.123 ± 0.036
2.792LeuTyr: 2.792 ± 0.066
0.0LeuXaa: 0.0 ± 0.0
Met
2.143MetAla: 2.143 ± 0.051
0.208MetCys: 0.208 ± 0.014
1.107MetAsp: 1.107 ± 0.031
1.013MetGlu: 1.013 ± 0.034
0.908MetPhe: 0.908 ± 0.031
1.612MetGly: 1.612 ± 0.048
0.559MetHis: 0.559 ± 0.023
1.624MetIle: 1.624 ± 0.039
1.517MetLys: 1.517 ± 0.041
2.574MetLeu: 2.574 ± 0.056
0.741MetMet: 0.741 ± 0.029
1.397MetAsn: 1.397 ± 0.036
1.17MetPro: 1.17 ± 0.042
1.532MetGln: 1.532 ± 0.039
1.146MetArg: 1.146 ± 0.03
1.908MetSer: 1.908 ± 0.041
1.549MetThr: 1.549 ± 0.039
1.537MetVal: 1.537 ± 0.045
0.227MetTrp: 0.227 ± 0.015
0.597MetTyr: 0.597 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
4.003AsnAla: 4.003 ± 0.08
0.393AsnCys: 0.393 ± 0.021
2.349AsnAsp: 2.349 ± 0.049
2.605AsnGlu: 2.605 ± 0.049
2.049AsnPhe: 2.049 ± 0.051
2.847AsnGly: 2.847 ± 0.07
1.122AsnHis: 1.122 ± 0.034
3.664AsnIle: 3.664 ± 0.084
2.792AsnLys: 2.792 ± 0.072
4.669AsnLeu: 4.669 ± 0.08
1.098AsnMet: 1.098 ± 0.029
2.297AsnAsn: 2.297 ± 0.072
2.311AsnPro: 2.311 ± 0.052
2.69AsnGln: 2.69 ± 0.057
1.91AsnArg: 1.91 ± 0.051
2.708AsnSer: 2.708 ± 0.056
2.76AsnThr: 2.76 ± 0.08
2.892AsnVal: 2.892 ± 0.065
0.554AsnTrp: 0.554 ± 0.021
1.689AsnTyr: 1.689 ± 0.044
0.0AsnXaa: 0.0 ± 0.0
Pro
2.803ProAla: 2.803 ± 0.051
0.288ProCys: 0.288 ± 0.016
2.093ProAsp: 2.093 ± 0.049
3.255ProGlu: 3.255 ± 0.061
1.686ProPhe: 1.686 ± 0.035
1.429ProGly: 1.429 ± 0.037
0.945ProHis: 0.945 ± 0.032
2.677ProIle: 2.677 ± 0.055
2.498ProLys: 2.498 ± 0.054
3.702ProLeu: 3.702 ± 0.062
0.936ProMet: 0.936 ± 0.028
2.108ProAsn: 2.108 ± 0.049
1.085ProPro: 1.085 ± 0.039
1.902ProGln: 1.902 ± 0.045
1.392ProArg: 1.392 ± 0.04
2.288ProSer: 2.288 ± 0.047
2.279ProThr: 2.279 ± 0.051
2.926ProVal: 2.926 ± 0.222
0.421ProTrp: 0.421 ± 0.02
1.366ProTyr: 1.366 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
4.929GlnAla: 4.929 ± 0.073
0.419GlnCys: 0.419 ± 0.022
2.497GlnAsp: 2.497 ± 0.051
2.752GlnGlu: 2.752 ± 0.065
2.189GlnPhe: 2.189 ± 0.044
3.014GlnGly: 3.014 ± 0.06
1.717GlnHis: 1.717 ± 0.056
3.623GlnIle: 3.623 ± 0.062
3.35GlnLys: 3.35 ± 0.067
5.604GlnLeu: 5.604 ± 0.094
1.271GlnMet: 1.271 ± 0.035
2.7GlnAsn: 2.7 ± 0.061
2.009GlnPro: 2.009 ± 0.044
4.086GlnGln: 4.086 ± 0.104
2.505GlnArg: 2.505 ± 0.057
2.996GlnSer: 2.996 ± 0.066
2.634GlnThr: 2.634 ± 0.051
3.35GlnVal: 3.35 ± 0.051
0.665GlnTrp: 0.665 ± 0.026
1.825GlnTyr: 1.825 ± 0.047
0.0GlnXaa: 0.0 ± 0.0
Arg
3.167ArgAla: 3.167 ± 0.068
0.368ArgCys: 0.368 ± 0.022
2.172ArgAsp: 2.172 ± 0.056
2.69ArgGlu: 2.69 ± 0.064
2.073ArgPhe: 2.073 ± 0.051
2.278ArgGly: 2.278 ± 0.055
1.134ArgHis: 1.134 ± 0.035
3.005ArgIle: 3.005 ± 0.06
2.459ArgLys: 2.459 ± 0.046
4.616ArgLeu: 4.616 ± 0.076
1.136ArgMet: 1.136 ± 0.034
1.797ArgAsn: 1.797 ± 0.04
1.649ArgPro: 1.649 ± 0.045
2.248ArgGln: 2.248 ± 0.05
2.032ArgArg: 2.032 ± 0.056
2.301ArgSer: 2.301 ± 0.048
2.058ArgThr: 2.058 ± 0.046
2.747ArgVal: 2.747 ± 0.049
0.505ArgTrp: 0.505 ± 0.024
1.69ArgTyr: 1.69 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
4.82SerAla: 4.82 ± 0.074
0.577SerCys: 0.577 ± 0.025
3.068SerAsp: 3.068 ± 0.058
3.486SerGlu: 3.486 ± 0.059
2.858SerPhe: 2.858 ± 0.049
3.954SerGly: 3.954 ± 0.077
1.461SerHis: 1.461 ± 0.037
4.309SerIle: 4.309 ± 0.068
3.533SerLys: 3.533 ± 0.061
6.204SerLeu: 6.204 ± 0.09
1.556SerMet: 1.556 ± 0.037
2.862SerAsn: 2.862 ± 0.058
2.316SerPro: 2.316 ± 0.113
2.898SerGln: 2.898 ± 0.055
2.408SerArg: 2.408 ± 0.054
3.959SerSer: 3.959 ± 0.07
3.506SerThr: 3.506 ± 0.071
3.683SerVal: 3.683 ± 0.062
0.616SerTrp: 0.616 ± 0.026
1.987SerTyr: 1.987 ± 0.045
0.0SerXaa: 0.0 ± 0.0
Thr
4.82ThrAla: 4.82 ± 0.083
0.466ThrCys: 0.466 ± 0.024
2.751ThrAsp: 2.751 ± 0.066
3.284ThrGlu: 3.284 ± 0.053
2.127ThrPhe: 2.127 ± 0.044
4.003ThrGly: 4.003 ± 0.099
1.315ThrHis: 1.315 ± 0.034
3.446ThrIle: 3.446 ± 0.073
2.485ThrLys: 2.485 ± 0.058
5.845ThrLeu: 5.845 ± 0.076
1.065ThrMet: 1.065 ± 0.032
2.092ThrAsn: 2.092 ± 0.109
2.603ThrPro: 2.603 ± 0.05
2.924ThrGln: 2.924 ± 0.059
2.139ThrArg: 2.139 ± 0.048
2.962ThrSer: 2.962 ± 0.063
3.167ThrThr: 3.167 ± 0.102
3.813ThrVal: 3.813 ± 0.107
0.702ThrTrp: 0.702 ± 0.028
1.56ThrTyr: 1.56 ± 0.033
0.0ThrXaa: 0.0 ± 0.0
Val
5.587ValAla: 5.587 ± 0.083
0.691ValCys: 0.691 ± 0.028
3.755ValAsp: 3.755 ± 0.065
4.41ValGlu: 4.41 ± 0.096
2.695ValPhe: 2.695 ± 0.05
4.259ValGly: 4.259 ± 0.075
1.263ValHis: 1.263 ± 0.038
4.633ValIle: 4.633 ± 0.069
3.831ValLys: 3.831 ± 0.073
6.638ValLeu: 6.638 ± 0.077
1.776ValMet: 1.776 ± 0.048
2.901ValAsn: 2.901 ± 0.061
2.526ValPro: 2.526 ± 0.054
2.885ValGln: 2.885 ± 0.053
2.683ValArg: 2.683 ± 0.053
4.073ValSer: 4.073 ± 0.121
3.606ValThr: 3.606 ± 0.113
4.612ValVal: 4.612 ± 0.082
0.779ValTrp: 0.779 ± 0.026
1.817ValTyr: 1.817 ± 0.047
0.0ValXaa: 0.0 ± 0.0
Trp
0.866TrpAla: 0.866 ± 0.033
0.157TrpCys: 0.157 ± 0.011
0.547TrpAsp: 0.547 ± 0.025
0.495TrpGlu: 0.495 ± 0.024
0.597TrpPhe: 0.597 ± 0.022
0.668TrpGly: 0.668 ± 0.026
0.316TrpHis: 0.316 ± 0.018
0.86TrpIle: 0.86 ± 0.028
0.685TrpLys: 0.685 ± 0.025
1.607TrpLeu: 1.607 ± 0.045
0.398TrpMet: 0.398 ± 0.021
0.563TrpAsn: 0.563 ± 0.024
0.279TrpPro: 0.279 ± 0.014
0.794TrpGln: 0.794 ± 0.031
0.59TrpArg: 0.59 ± 0.026
0.722TrpSer: 0.722 ± 0.026
0.596TrpThr: 0.596 ± 0.027
0.86TrpVal: 0.86 ± 0.03
0.14TrpTrp: 0.14 ± 0.013
0.407TrpTyr: 0.407 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.801TyrAla: 2.801 ± 0.054
0.394TyrCys: 0.394 ± 0.02
1.769TyrAsp: 1.769 ± 0.047
1.746TyrGlu: 1.746 ± 0.046
1.682TyrPhe: 1.682 ± 0.048
2.104TyrGly: 2.104 ± 0.051
0.762TyrHis: 0.762 ± 0.029
2.02TyrIle: 2.02 ± 0.047
1.759TyrLys: 1.759 ± 0.05
3.662TyrLeu: 3.662 ± 0.068
0.636TyrMet: 0.636 ± 0.025
1.299TyrAsn: 1.299 ± 0.035
1.375TyrPro: 1.375 ± 0.038
2.022TyrGln: 2.022 ± 0.044
1.6TyrArg: 1.6 ± 0.048
1.988TyrSer: 1.988 ± 0.042
1.617TyrThr: 1.617 ± 0.041
1.988TyrVal: 1.988 ± 0.044
0.48TyrTrp: 0.48 ± 0.023
1.061TyrTyr: 1.061 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3434 proteins (1039734 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski