Amino acid dipepetide frequency for Terrilactibacillus tamarindi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.612AlaAla: 4.612 ± 0.099
0.679AlaCys: 0.679 ± 0.029
2.861AlaAsp: 2.861 ± 0.059
3.85AlaGlu: 3.85 ± 0.081
3.055AlaPhe: 3.055 ± 0.059
4.575AlaGly: 4.575 ± 0.082
1.285AlaHis: 1.285 ± 0.044
6.034AlaIle: 6.034 ± 0.102
4.714AlaLys: 4.714 ± 0.075
6.965AlaLeu: 6.965 ± 0.099
1.888AlaMet: 1.888 ± 0.051
2.532AlaAsn: 2.532 ± 0.049
1.935AlaPro: 1.935 ± 0.048
2.024AlaGln: 2.024 ± 0.058
2.404AlaArg: 2.404 ± 0.053
3.967AlaSer: 3.967 ± 0.072
3.378AlaThr: 3.378 ± 0.062
4.639AlaVal: 4.639 ± 0.08
0.528AlaTrp: 0.528 ± 0.023
2.301AlaTyr: 2.301 ± 0.055
0.0AlaXaa: 0.0 ± 0.0
Cys
0.503CysAla: 0.503 ± 0.028
0.124CysCys: 0.124 ± 0.011
0.479CysAsp: 0.479 ± 0.024
0.493CysGlu: 0.493 ± 0.026
0.392CysPhe: 0.392 ± 0.023
0.784CysGly: 0.784 ± 0.033
0.283CysHis: 0.283 ± 0.017
0.641CysIle: 0.641 ± 0.03
0.42CysLys: 0.42 ± 0.025
0.924CysLeu: 0.924 ± 0.034
0.211CysMet: 0.211 ± 0.015
0.283CysAsn: 0.283 ± 0.017
0.466CysPro: 0.466 ± 0.026
0.338CysGln: 0.338 ± 0.02
0.322CysArg: 0.322 ± 0.02
0.523CysSer: 0.523 ± 0.025
0.418CysThr: 0.418 ± 0.023
0.456CysVal: 0.456 ± 0.022
0.066CysTrp: 0.066 ± 0.009
0.314CysTyr: 0.314 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
3.099AspAla: 3.099 ± 0.061
0.423AspCys: 0.423 ± 0.021
2.751AspAsp: 2.751 ± 0.074
3.985AspGlu: 3.985 ± 0.073
2.309AspPhe: 2.309 ± 0.052
3.111AspGly: 3.111 ± 0.063
1.551AspHis: 1.551 ± 0.043
4.608AspIle: 4.608 ± 0.083
3.594AspLys: 3.594 ± 0.07
5.277AspLeu: 5.277 ± 0.085
1.527AspMet: 1.527 ± 0.045
1.925AspAsn: 1.925 ± 0.049
2.111AspPro: 2.111 ± 0.058
2.524AspGln: 2.524 ± 0.055
2.393AspArg: 2.393 ± 0.053
2.633AspSer: 2.633 ± 0.057
2.516AspThr: 2.516 ± 0.057
3.908AspVal: 3.908 ± 0.079
0.6AspTrp: 0.6 ± 0.029
2.243AspTyr: 2.243 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
4.887GluAla: 4.887 ± 0.092
0.458GluCys: 0.458 ± 0.024
3.489GluAsp: 3.489 ± 0.062
5.321GluGlu: 5.321 ± 0.098
2.111GluPhe: 2.111 ± 0.056
3.889GluGly: 3.889 ± 0.07
1.548GluHis: 1.548 ± 0.042
4.783GluIle: 4.783 ± 0.079
6.171GluLys: 6.171 ± 0.08
6.081GluLeu: 6.081 ± 0.093
1.876GluMet: 1.876 ± 0.045
3.391GluAsn: 3.391 ± 0.07
1.921GluPro: 1.921 ± 0.055
2.93GluGln: 2.93 ± 0.071
3.271GluArg: 3.271 ± 0.072
3.578GluSer: 3.578 ± 0.073
3.657GluThr: 3.657 ± 0.073
4.098GluVal: 4.098 ± 0.087
0.707GluTrp: 0.707 ± 0.028
1.804GluTyr: 1.804 ± 0.048
0.0GluXaa: 0.0 ± 0.0
Phe
2.628PheAla: 2.628 ± 0.064
0.44PheCys: 0.44 ± 0.023
2.454PheAsp: 2.454 ± 0.054
2.602PheGlu: 2.602 ± 0.062
2.194PhePhe: 2.194 ± 0.061
3.415PheGly: 3.415 ± 0.06
1.088PheHis: 1.088 ± 0.038
4.143PheIle: 4.143 ± 0.094
2.621PheLys: 2.621 ± 0.055
4.395PheLeu: 4.395 ± 0.085
1.112PheMet: 1.112 ± 0.035
2.071PheAsn: 2.071 ± 0.053
1.658PhePro: 1.658 ± 0.04
1.486PheGln: 1.486 ± 0.043
1.482PheArg: 1.482 ± 0.04
3.2PheSer: 3.2 ± 0.059
2.373PheThr: 2.373 ± 0.055
3.044PheVal: 3.044 ± 0.064
0.424PheTrp: 0.424 ± 0.022
1.64PheTyr: 1.64 ± 0.051
0.0PheXaa: 0.0 ± 0.0
Gly
4.453GlyAla: 4.453 ± 0.082
0.649GlyCys: 0.649 ± 0.028
3.136GlyAsp: 3.136 ± 0.063
3.869GlyGlu: 3.869 ± 0.079
3.423GlyPhe: 3.423 ± 0.068
4.686GlyGly: 4.686 ± 0.089
1.665GlyHis: 1.665 ± 0.048
6.008GlyIle: 6.008 ± 0.103
5.008GlyLys: 5.008 ± 0.09
6.716GlyLeu: 6.716 ± 0.095
2.008GlyMet: 2.008 ± 0.049
2.496GlyAsn: 2.496 ± 0.06
1.782GlyPro: 1.782 ± 0.048
2.421GlyGln: 2.421 ± 0.055
2.629GlyArg: 2.629 ± 0.061
4.008GlySer: 4.008 ± 0.077
3.796GlyThr: 3.796 ± 0.071
4.838GlyVal: 4.838 ± 0.08
0.751GlyTrp: 0.751 ± 0.036
2.875GlyTyr: 2.875 ± 0.064
0.0GlyXaa: 0.0 ± 0.0
His
1.443HisAla: 1.443 ± 0.043
0.228HisCys: 0.228 ± 0.016
1.27HisAsp: 1.27 ± 0.039
1.439HisGlu: 1.439 ± 0.041
1.247HisPhe: 1.247 ± 0.045
1.504HisGly: 1.504 ± 0.039
0.973HisHis: 0.973 ± 0.04
1.851HisIle: 1.851 ± 0.048
1.147HisLys: 1.147 ± 0.035
2.607HisLeu: 2.607 ± 0.053
0.593HisMet: 0.593 ± 0.027
0.807HisAsn: 0.807 ± 0.031
1.272HisPro: 1.272 ± 0.043
1.083HisGln: 1.083 ± 0.035
1.023HisArg: 1.023 ± 0.034
1.359HisSer: 1.359 ± 0.039
1.124HisThr: 1.124 ± 0.034
1.729HisVal: 1.729 ± 0.052
0.262HisTrp: 0.262 ± 0.017
1.031HisTyr: 1.031 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.595IleAla: 5.595 ± 0.091
0.75IleCys: 0.75 ± 0.027
4.851IleAsp: 4.851 ± 0.085
5.573IleGlu: 5.573 ± 0.077
3.334IlePhe: 3.334 ± 0.072
6.259IleGly: 6.259 ± 0.102
2.053IleHis: 2.053 ± 0.054
6.573IleIle: 6.573 ± 0.109
5.659IleLys: 5.659 ± 0.078
7.623IleLeu: 7.623 ± 0.112
1.797IleMet: 1.797 ± 0.048
3.659IleAsn: 3.659 ± 0.062
3.523IlePro: 3.523 ± 0.075
3.365IleGln: 3.365 ± 0.065
3.257IleArg: 3.257 ± 0.07
5.307IleSer: 5.307 ± 0.088
4.366IleThr: 4.366 ± 0.078
5.713IleVal: 5.713 ± 0.099
0.667IleTrp: 0.667 ± 0.031
2.604IleTyr: 2.604 ± 0.051
0.0IleXaa: 0.0 ± 0.0
Lys
4.647LysAla: 4.647 ± 0.077
0.435LysCys: 0.435 ± 0.022
4.213LysAsp: 4.213 ± 0.082
6.346LysGlu: 6.346 ± 0.095
1.879LysPhe: 1.879 ± 0.051
4.652LysGly: 4.652 ± 0.079
1.625LysHis: 1.625 ± 0.045
5.105LysIle: 5.105 ± 0.074
6.884LysLys: 6.884 ± 0.108
6.239LysLeu: 6.239 ± 0.092
2.247LysMet: 2.247 ± 0.051
3.665LysAsn: 3.665 ± 0.077
2.428LysPro: 2.428 ± 0.048
3.489LysGln: 3.489 ± 0.066
3.56LysArg: 3.56 ± 0.066
4.107LysSer: 4.107 ± 0.079
4.074LysThr: 4.074 ± 0.078
4.968LysVal: 4.968 ± 0.092
0.801LysTrp: 0.801 ± 0.032
2.351LysTyr: 2.351 ± 0.06
0.0LysXaa: 0.0 ± 0.0
Leu
6.671LeuAla: 6.671 ± 0.081
0.841LeuCys: 0.841 ± 0.035
5.317LeuAsp: 5.317 ± 0.076
5.813LeuGlu: 5.813 ± 0.097
4.889LeuPhe: 4.889 ± 0.093
6.425LeuGly: 6.425 ± 0.096
1.984LeuHis: 1.984 ± 0.04
8.174LeuIle: 8.174 ± 0.132
7.182LeuLys: 7.182 ± 0.101
9.714LeuLeu: 9.714 ± 0.149
2.477LeuMet: 2.477 ± 0.059
4.855LeuAsn: 4.855 ± 0.079
3.783LeuPro: 3.783 ± 0.076
3.22LeuGln: 3.22 ± 0.06
3.601LeuArg: 3.601 ± 0.07
7.402LeuSer: 7.402 ± 0.098
5.864LeuThr: 5.864 ± 0.082
6.222LeuVal: 6.222 ± 0.097
0.81LeuTrp: 0.81 ± 0.036
3.041LeuTyr: 3.041 ± 0.063
0.0LeuXaa: 0.0 ± 0.0
Met
1.976MetAla: 1.976 ± 0.049
0.161MetCys: 0.161 ± 0.013
1.474MetAsp: 1.474 ± 0.045
1.608MetGlu: 1.608 ± 0.051
0.922MetPhe: 0.922 ± 0.035
1.847MetGly: 1.847 ± 0.048
0.448MetHis: 0.448 ± 0.022
2.381MetIle: 2.381 ± 0.05
2.361MetLys: 2.361 ± 0.046
2.29MetLeu: 2.29 ± 0.048
0.875MetMet: 0.875 ± 0.037
1.546MetAsn: 1.546 ± 0.042
0.978MetPro: 0.978 ± 0.034
0.827MetGln: 0.827 ± 0.032
1.094MetArg: 1.094 ± 0.04
1.788MetSer: 1.788 ± 0.049
1.851MetThr: 1.851 ± 0.048
1.812MetVal: 1.812 ± 0.05
0.171MetTrp: 0.171 ± 0.016
0.661MetTyr: 0.661 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
2.519AsnAla: 2.519 ± 0.055
0.329AsnCys: 0.329 ± 0.02
2.492AsnAsp: 2.492 ± 0.056
3.231AsnGlu: 3.231 ± 0.058
1.598AsnPhe: 1.598 ± 0.042
3.155AsnGly: 3.155 ± 0.069
1.398AsnHis: 1.398 ± 0.042
3.478AsnIle: 3.478 ± 0.068
3.444AsnLys: 3.444 ± 0.077
3.966AsnLeu: 3.966 ± 0.073
1.237AsnMet: 1.237 ± 0.039
2.047AsnAsn: 2.047 ± 0.069
2.193AsnPro: 2.193 ± 0.055
2.396AsnGln: 2.396 ± 0.055
2.105AsnArg: 2.105 ± 0.048
2.228AsnSer: 2.228 ± 0.055
2.132AsnThr: 2.132 ± 0.054
2.996AsnVal: 2.996 ± 0.057
0.508AsnTrp: 0.508 ± 0.027
1.699AsnTyr: 1.699 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
1.984ProAla: 1.984 ± 0.055
0.259ProCys: 0.259 ± 0.02
2.061ProAsp: 2.061 ± 0.049
2.808ProGlu: 2.808 ± 0.062
2.011ProPhe: 2.011 ± 0.048
2.273ProGly: 2.273 ± 0.065
0.847ProHis: 0.847 ± 0.033
3.141ProIle: 3.141 ± 0.055
2.516ProLys: 2.516 ± 0.055
3.552ProLeu: 3.552 ± 0.071
0.823ProMet: 0.823 ± 0.03
1.925ProAsn: 1.925 ± 0.052
0.942ProPro: 0.942 ± 0.035
1.13ProGln: 1.13 ± 0.037
1.13ProArg: 1.13 ± 0.039
2.577ProSer: 2.577 ± 0.059
2.032ProThr: 2.032 ± 0.048
2.669ProVal: 2.669 ± 0.061
0.361ProTrp: 0.361 ± 0.022
1.522ProTyr: 1.522 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
2.739GlnAla: 2.739 ± 0.068
0.241GlnCys: 0.241 ± 0.016
1.986GlnAsp: 1.986 ± 0.047
2.506GlnGlu: 2.506 ± 0.061
1.823GlnPhe: 1.823 ± 0.063
2.265GlnGly: 2.265 ± 0.053
0.865GlnHis: 0.865 ± 0.029
2.881GlnIle: 2.881 ± 0.059
2.968GlnLys: 2.968 ± 0.066
4.158GlnLeu: 4.158 ± 0.068
1.228GlnMet: 1.228 ± 0.038
1.776GlnAsn: 1.776 ± 0.051
1.255GlnPro: 1.255 ± 0.039
1.506GlnGln: 1.506 ± 0.05
1.495GlnArg: 1.495 ± 0.046
2.52GlnSer: 2.52 ± 0.056
2.285GlnThr: 2.285 ± 0.056
2.509GlnVal: 2.509 ± 0.048
0.372GlnTrp: 0.372 ± 0.019
1.351GlnTyr: 1.351 ± 0.041
0.0GlnXaa: 0.0 ± 0.0
Arg
2.346ArgAla: 2.346 ± 0.044
0.334ArgCys: 0.334 ± 0.02
2.163ArgAsp: 2.163 ± 0.059
2.903ArgGlu: 2.903 ± 0.06
1.9ArgPhe: 1.9 ± 0.047
2.256ArgGly: 2.256 ± 0.054
0.981ArgHis: 0.981 ± 0.034
3.237ArgIle: 3.237 ± 0.057
3.173ArgLys: 3.173 ± 0.064
4.288ArgLeu: 4.288 ± 0.074
1.205ArgMet: 1.205 ± 0.033
1.749ArgAsn: 1.749 ± 0.048
1.371ArgPro: 1.371 ± 0.041
1.729ArgGln: 1.729 ± 0.05
1.993ArgArg: 1.993 ± 0.058
2.298ArgSer: 2.298 ± 0.059
2.077ArgThr: 2.077 ± 0.051
2.541ArgVal: 2.541 ± 0.054
0.366ArgTrp: 0.366 ± 0.022
1.687ArgTyr: 1.687 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
3.556SerAla: 3.556 ± 0.074
0.497SerCys: 0.497 ± 0.027
3.128SerAsp: 3.128 ± 0.072
3.839SerGlu: 3.839 ± 0.064
3.278SerPhe: 3.278 ± 0.07
4.472SerGly: 4.472 ± 0.083
1.533SerHis: 1.533 ± 0.042
5.443SerIle: 5.443 ± 0.087
4.418SerLys: 4.418 ± 0.088
6.492SerLeu: 6.492 ± 0.106
1.682SerMet: 1.682 ± 0.043
2.739SerAsn: 2.739 ± 0.057
2.217SerPro: 2.217 ± 0.069
2.256SerGln: 2.256 ± 0.059
2.442SerArg: 2.442 ± 0.057
4.059SerSer: 4.059 ± 0.084
3.43SerThr: 3.43 ± 0.059
4.114SerVal: 4.114 ± 0.073
0.561SerTrp: 0.561 ± 0.026
2.236SerTyr: 2.236 ± 0.053
0.0SerXaa: 0.0 ± 0.0
Thr
3.39ThrAla: 3.39 ± 0.059
0.477ThrCys: 0.477 ± 0.022
2.674ThrAsp: 2.674 ± 0.058
3.148ThrGlu: 3.148 ± 0.067
2.827ThrPhe: 2.827 ± 0.051
4.016ThrGly: 4.016 ± 0.075
1.2ThrHis: 1.2 ± 0.035
4.883ThrIle: 4.883 ± 0.081
3.644ThrLys: 3.644 ± 0.066
5.772ThrLeu: 5.772 ± 0.087
1.381ThrMet: 1.381 ± 0.036
2.547ThrAsn: 2.547 ± 0.059
2.396ThrPro: 2.396 ± 0.06
1.693ThrGln: 1.693 ± 0.048
1.861ThrArg: 1.861 ± 0.051
3.462ThrSer: 3.462 ± 0.068
3.018ThrThr: 3.018 ± 0.068
3.949ThrVal: 3.949 ± 0.073
0.51ThrTrp: 0.51 ± 0.028
2.026ThrTyr: 2.026 ± 0.048
0.0ThrXaa: 0.0 ± 0.0
Val
4.592ValAla: 4.592 ± 0.079
0.679ValCys: 0.679 ± 0.029
3.717ValAsp: 3.717 ± 0.077
3.92ValGlu: 3.92 ± 0.076
2.995ValPhe: 2.995 ± 0.056
4.608ValGly: 4.608 ± 0.075
1.367ValHis: 1.367 ± 0.04
5.828ValIle: 5.828 ± 0.098
4.872ValLys: 4.872 ± 0.087
6.374ValLeu: 6.374 ± 0.094
1.786ValMet: 1.786 ± 0.04
3.256ValAsn: 3.256 ± 0.07
2.616ValPro: 2.616 ± 0.057
2.305ValGln: 2.305 ± 0.053
2.479ValArg: 2.479 ± 0.056
4.744ValSer: 4.744 ± 0.082
4.117ValThr: 4.117 ± 0.069
4.781ValVal: 4.781 ± 0.089
0.589ValTrp: 0.589 ± 0.029
2.185ValTyr: 2.185 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.494TrpAla: 0.494 ± 0.023
0.097TrpCys: 0.097 ± 0.011
0.513TrpAsp: 0.513 ± 0.025
0.527TrpGlu: 0.527 ± 0.026
0.533TrpPhe: 0.533 ± 0.028
0.593TrpGly: 0.593 ± 0.03
0.217TrpHis: 0.217 ± 0.016
0.844TrpIle: 0.844 ± 0.031
0.705TrpLys: 0.705 ± 0.03
1.156TrpLeu: 1.156 ± 0.044
0.313TrpMet: 0.313 ± 0.018
0.475TrpAsn: 0.475 ± 0.021
0.248TrpPro: 0.248 ± 0.017
0.353TrpGln: 0.353 ± 0.02
0.39TrpArg: 0.39 ± 0.025
0.565TrpSer: 0.565 ± 0.029
0.493TrpThr: 0.493 ± 0.027
0.604TrpVal: 0.604 ± 0.032
0.118TrpTrp: 0.118 ± 0.013
0.323TrpTyr: 0.323 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.095TyrAla: 2.095 ± 0.054
0.339TyrCys: 0.339 ± 0.018
2.055TyrAsp: 2.055 ± 0.049
2.191TyrGlu: 2.191 ± 0.053
1.749TyrPhe: 1.749 ± 0.05
2.431TyrGly: 2.431 ± 0.061
1.082TyrHis: 1.082 ± 0.034
2.492TyrIle: 2.492 ± 0.055
2.213TyrLys: 2.213 ± 0.052
3.697TyrLeu: 3.697 ± 0.062
0.806TyrMet: 0.806 ± 0.034
1.408TyrAsn: 1.408 ± 0.046
1.465TyrPro: 1.465 ± 0.044
1.657TyrGln: 1.657 ± 0.05
1.666TyrArg: 1.666 ± 0.045
2.069TyrSer: 2.069 ± 0.049
1.873TyrThr: 1.873 ± 0.052
2.223TyrVal: 2.223 ± 0.052
0.386TyrTrp: 0.386 ± 0.022
1.435TyrTyr: 1.435 ± 0.046
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2956 proteins (876471 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski