Amino acid dipepetide frequency for Sanguibacteroides justesenii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.691AlaAla: 4.691 ± 0.083	0.925AlaCys: 0.925 ± 0.031	3.55AlaAsp: 3.55 ± 0.077	4.29AlaGlu: 4.29 ± 0.069	3.069AlaPhe: 3.069 ± 0.058	4.784AlaGly: 4.784 ± 0.08	1.086AlaHis: 1.086 ± 0.04	4.963AlaIle: 4.963 ± 0.09	4.098AlaLys: 4.098 ± 0.068	6.25AlaLeu: 6.25 ± 0.083	1.737AlaMet: 1.737 ± 0.049	2.794AlaAsn: 2.794 ± 0.05	1.962AlaPro: 1.962 ± 0.042	2.067AlaGln: 2.067 ± 0.048	3.006AlaArg: 3.006 ± 0.058	3.647AlaSer: 3.647 ± 0.062	3.268AlaThr: 3.268 ± 0.059	4.43AlaVal: 4.43 ± 0.075	0.696AlaTrp: 0.696 ± 0.033	2.819AlaTyr: 2.819 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.59CysAla: 0.59 ± 0.028	0.212CysCys: 0.212 ± 0.017	0.583CysAsp: 0.583 ± 0.022	0.618CysGlu: 0.618 ± 0.025	0.655CysPhe: 0.655 ± 0.021	0.962CysGly: 0.962 ± 0.033	0.22CysHis: 0.22 ± 0.016	0.952CysIle: 0.952 ± 0.038	0.667CysLys: 0.667 ± 0.026	0.933CysLeu: 0.933 ± 0.031	0.286CysMet: 0.286 ± 0.017	0.513CysAsn: 0.513 ± 0.023	0.44CysPro: 0.44 ± 0.025	0.284CysGln: 0.284 ± 0.017	0.633CysArg: 0.633 ± 0.025	0.696CysSer: 0.696 ± 0.027	0.572CysThr: 0.572 ± 0.022	0.706CysVal: 0.706 ± 0.031	0.137CysTrp: 0.137 ± 0.011	0.5CysTyr: 0.5 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	3.185AspAla: 3.185 ± 0.057	0.527AspCys: 0.527 ± 0.024	2.381AspAsp: 2.381 ± 0.054	3.574AspGlu: 3.574 ± 0.062	3.012AspPhe: 3.012 ± 0.056	3.367AspGly: 3.367 ± 0.067	0.853AspHis: 0.853 ± 0.029	4.35AspIle: 4.35 ± 0.067	3.861AspLys: 3.861 ± 0.061	4.844AspLeu: 4.844 ± 0.084	1.551AspMet: 1.551 ± 0.041	2.414AspAsn: 2.414 ± 0.05	2.161AspPro: 2.161 ± 0.048	1.358AspGln: 1.358 ± 0.041	2.873AspArg: 2.873 ± 0.066	3.051AspSer: 3.051 ± 0.067	2.663AspThr: 2.663 ± 0.058	3.445AspVal: 3.445 ± 0.066	0.68AspTrp: 0.68 ± 0.029	2.785AspTyr: 2.785 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	4.488GluAla: 4.488 ± 0.076	0.594GluCys: 0.594 ± 0.025	3.269GluAsp: 3.269 ± 0.066	5.902GluGlu: 5.902 ± 0.101	2.781GluPhe: 2.781 ± 0.049	4.317GluGly: 4.317 ± 0.067	1.202GluHis: 1.202 ± 0.04	5.697GluIle: 5.697 ± 0.091	6.119GluLys: 6.119 ± 0.088	6.338GluLeu: 6.338 ± 0.089	2.061GluMet: 2.061 ± 0.05	3.713GluAsn: 3.713 ± 0.067	1.702GluPro: 1.702 ± 0.042	2.391GluGln: 2.391 ± 0.052	3.704GluArg: 3.704 ± 0.072	3.261GluSer: 3.261 ± 0.058	3.209GluThr: 3.209 ± 0.055	4.736GluVal: 4.736 ± 0.069	0.872GluTrp: 0.872 ± 0.032	2.829GluTyr: 2.829 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.945PheAla: 2.945 ± 0.054	0.597PheCys: 0.597 ± 0.028	2.755PheAsp: 2.755 ± 0.055	2.778PheGlu: 2.778 ± 0.055	2.605PhePhe: 2.605 ± 0.068	3.177PheGly: 3.177 ± 0.066	0.897PheHis: 0.897 ± 0.027	3.649PheIle: 3.649 ± 0.078	2.736PheLys: 2.736 ± 0.055	4.594PheLeu: 4.594 ± 0.092	1.399PheMet: 1.399 ± 0.043	2.305PheAsn: 2.305 ± 0.057	1.895PhePro: 1.895 ± 0.048	1.367PheGln: 1.367 ± 0.04	2.318PheArg: 2.318 ± 0.052	3.758PheSer: 3.758 ± 0.064	2.847PheThr: 2.847 ± 0.066	3.281PheVal: 3.281 ± 0.068	0.571PheTrp: 0.571 ± 0.028	2.235PheTyr: 2.235 ± 0.055	0.0PheXaa: 0.0 ± 0.0
Gly	3.993GlyAla: 3.993 ± 0.068	0.928GlyCys: 0.928 ± 0.032	3.469GlyAsp: 3.469 ± 0.063	4.843GlyGlu: 4.843 ± 0.075	3.377GlyPhe: 3.377 ± 0.066	4.738GlyGly: 4.738 ± 0.094	1.206GlyHis: 1.206 ± 0.04	6.113GlyIle: 6.113 ± 0.09	5.61GlyLys: 5.61 ± 0.081	5.9GlyLeu: 5.9 ± 0.089	2.087GlyMet: 2.087 ± 0.047	3.341GlyAsn: 3.341 ± 0.055	1.302GlyPro: 1.302 ± 0.043	1.838GlyGln: 1.838 ± 0.04	2.971GlyArg: 2.971 ± 0.063	3.834GlySer: 3.834 ± 0.07	3.686GlyThr: 3.686 ± 0.072	4.871GlyVal: 4.871 ± 0.076	0.809GlyTrp: 0.809 ± 0.033	3.083GlyTyr: 3.083 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.048HisAla: 1.048 ± 0.039	0.23HisCys: 0.23 ± 0.016	0.852HisAsp: 0.852 ± 0.035	1.018HisGlu: 1.018 ± 0.034	1.031HisPhe: 1.031 ± 0.037	1.055HisGly: 1.055 ± 0.033	0.386HisHis: 0.386 ± 0.024	1.288HisIle: 1.288 ± 0.036	0.956HisLys: 0.956 ± 0.03	1.676HisLeu: 1.676 ± 0.054	0.441HisMet: 0.441 ± 0.023	0.79HisAsn: 0.79 ± 0.03	1.006HisPro: 1.006 ± 0.039	0.55HisGln: 0.55 ± 0.025	0.91HisArg: 0.91 ± 0.032	1.108HisSer: 1.108 ± 0.035	0.87HisThr: 0.87 ± 0.031	1.074HisVal: 1.074 ± 0.035	0.203HisTrp: 0.203 ± 0.016	0.862HisTyr: 0.862 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.419IleAla: 5.419 ± 0.085	0.873IleCys: 0.873 ± 0.033	4.288IleAsp: 4.288 ± 0.077	4.992IleGlu: 4.992 ± 0.076	3.3IlePhe: 3.3 ± 0.072	5.135IleGly: 5.135 ± 0.085	1.45IleHis: 1.45 ± 0.036	5.164IleIle: 5.164 ± 0.095	4.605IleLys: 4.605 ± 0.084	6.998IleLeu: 6.998 ± 0.11	1.629IleMet: 1.629 ± 0.039	3.427IleAsn: 3.427 ± 0.07	3.562IlePro: 3.562 ± 0.066	2.409IleGln: 2.409 ± 0.046	4.15IleArg: 4.15 ± 0.073	4.754IleSer: 4.754 ± 0.073	4.322IleThr: 4.322 ± 0.069	5.234IleVal: 5.234 ± 0.085	0.706IleTrp: 0.706 ± 0.029	2.993IleTyr: 2.993 ± 0.061	0.0IleXaa: 0.0 ± 0.0
Lys	4.562LysAla: 4.562 ± 0.074	0.501LysCys: 0.501 ± 0.028	3.81LysAsp: 3.81 ± 0.076	6.403LysGlu: 6.403 ± 0.09	2.265LysPhe: 2.265 ± 0.048	4.656LysGly: 4.656 ± 0.072	1.16LysHis: 1.16 ± 0.032	5.313LysIle: 5.313 ± 0.072	5.452LysLys: 5.452 ± 0.098	5.526LysLeu: 5.526 ± 0.069	2.113LysMet: 2.113 ± 0.041	3.87LysAsn: 3.87 ± 0.063	2.187LysPro: 2.187 ± 0.053	2.483LysGln: 2.483 ± 0.058	3.689LysArg: 3.689 ± 0.073	3.528LysSer: 3.528 ± 0.061	3.614LysThr: 3.614 ± 0.062	4.362LysVal: 4.362 ± 0.059	0.791LysTrp: 0.791 ± 0.027	3.022LysTyr: 3.022 ± 0.059	0.0LysXaa: 0.0 ± 0.0
Leu	5.909LeuAla: 5.909 ± 0.1	1.166LeuCys: 1.166 ± 0.034	4.461LeuAsp: 4.461 ± 0.071	5.607LeuGlu: 5.607 ± 0.076	5.364LeuPhe: 5.364 ± 0.105	5.987LeuGly: 5.987 ± 0.081	1.623LeuHis: 1.623 ± 0.045	6.425LeuIle: 6.425 ± 0.095	6.992LeuLys: 6.992 ± 0.093	9.637LeuLeu: 9.637 ± 0.145	2.21LeuMet: 2.21 ± 0.051	4.737LeuAsn: 4.737 ± 0.076	4.127LeuPro: 4.127 ± 0.068	3.165LeuGln: 3.165 ± 0.062	4.436LeuArg: 4.436 ± 0.071	7.012LeuSer: 7.012 ± 0.089	5.401LeuThr: 5.401 ± 0.082	5.366LeuVal: 5.366 ± 0.088	0.977LeuTrp: 0.977 ± 0.037	3.779LeuTyr: 3.779 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	2.033MetAla: 2.033 ± 0.05	0.211MetCys: 0.211 ± 0.013	1.504MetAsp: 1.504 ± 0.039	1.975MetGlu: 1.975 ± 0.046	0.948MetPhe: 0.948 ± 0.039	1.907MetGly: 1.907 ± 0.042	0.427MetHis: 0.427 ± 0.022	1.858MetIle: 1.858 ± 0.048	2.432MetLys: 2.432 ± 0.05	2.315MetLeu: 2.315 ± 0.054	0.695MetMet: 0.695 ± 0.029	1.502MetAsn: 1.502 ± 0.039	1.015MetPro: 1.015 ± 0.036	0.899MetGln: 0.899 ± 0.028	1.198MetArg: 1.198 ± 0.037	1.579MetSer: 1.579 ± 0.039	1.385MetThr: 1.385 ± 0.039	1.57MetVal: 1.57 ± 0.041	0.184MetTrp: 0.184 ± 0.014	0.842MetTyr: 0.842 ± 0.033	0.0MetXaa: 0.0 ± 0.0
Asn	3.06AsnAla: 3.06 ± 0.068	0.446AsnCys: 0.446 ± 0.022	2.339AsnAsp: 2.339 ± 0.047	2.996AsnGlu: 2.996 ± 0.058	2.237AsnPhe: 2.237 ± 0.052	3.365AsnGly: 3.365 ± 0.062	0.853AsnHis: 0.853 ± 0.031	3.918AsnIle: 3.918 ± 0.063	3.129AsnLys: 3.129 ± 0.06	4.623AsnLeu: 4.623 ± 0.083	1.336AsnMet: 1.336 ± 0.041	2.379AsnAsn: 2.379 ± 0.054	2.422AsnPro: 2.422 ± 0.058	1.554AsnGln: 1.554 ± 0.04	2.822AsnArg: 2.822 ± 0.054	2.574AsnSer: 2.574 ± 0.053	2.626AsnThr: 2.626 ± 0.051	3.064AsnVal: 3.064 ± 0.059	0.558AsnTrp: 0.558 ± 0.027	2.411AsnTyr: 2.411 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	2.469ProAla: 2.469 ± 0.059	0.334ProCys: 0.334 ± 0.021	2.584ProAsp: 2.584 ± 0.05	3.495ProGlu: 3.495 ± 0.055	1.828ProPhe: 1.828 ± 0.047	2.713ProGly: 2.713 ± 0.054	0.618ProHis: 0.618 ± 0.025	2.244ProIle: 2.244 ± 0.06	1.963ProLys: 1.963 ± 0.053	3.395ProLeu: 3.395 ± 0.067	0.859ProMet: 0.859 ± 0.031	1.566ProAsn: 1.566 ± 0.04	0.973ProPro: 0.973 ± 0.036	1.135ProGln: 1.135 ± 0.033	1.364ProArg: 1.364 ± 0.042	2.1ProSer: 2.1 ± 0.046	1.848ProThr: 1.848 ± 0.047	3.195ProVal: 3.195 ± 0.061	0.398ProTrp: 0.398 ± 0.023	1.683ProTyr: 1.683 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	2.176GlnAla: 2.176 ± 0.052	0.238GlnCys: 0.238 ± 0.015	1.444GlnAsp: 1.444 ± 0.042	2.303GlnGlu: 2.303 ± 0.06	1.247GlnPhe: 1.247 ± 0.039	1.885GlnGly: 1.885 ± 0.043	0.557GlnHis: 0.557 ± 0.025	2.365GlnIle: 2.365 ± 0.047	2.572GlnLys: 2.572 ± 0.063	3.053GlnLeu: 3.053 ± 0.063	0.846GlnMet: 0.846 ± 0.031	1.664GlnAsn: 1.664 ± 0.05	1.025GlnPro: 1.025 ± 0.034	1.355GlnGln: 1.355 ± 0.045	1.585GlnArg: 1.585 ± 0.043	1.588GlnSer: 1.588 ± 0.037	1.684GlnThr: 1.684 ± 0.048	2.11GlnVal: 2.11 ± 0.046	0.361GlnTrp: 0.361 ± 0.022	1.269GlnTyr: 1.269 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.644ArgAla: 2.644 ± 0.051	0.448ArgCys: 0.448 ± 0.022	2.403ArgAsp: 2.403 ± 0.052	3.96ArgGlu: 3.96 ± 0.074	2.626ArgPhe: 2.626 ± 0.059	2.862ArgGly: 2.862 ± 0.057	0.906ArgHis: 0.906 ± 0.03	3.934ArgIle: 3.934 ± 0.07	3.686ArgLys: 3.686 ± 0.061	5.031ArgLeu: 5.031 ± 0.078	1.492ArgMet: 1.492 ± 0.038	2.56ArgAsn: 2.56 ± 0.047	1.559ArgPro: 1.559 ± 0.038	1.781ArgGln: 1.781 ± 0.046	2.485ArgArg: 2.485 ± 0.053	2.566ArgSer: 2.566 ± 0.052	2.203ArgThr: 2.203 ± 0.045	3.433ArgVal: 3.433 ± 0.054	0.738ArgTrp: 0.738 ± 0.028	2.539ArgTyr: 2.539 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	3.544SerAla: 3.544 ± 0.063	0.844SerCys: 0.844 ± 0.032	3.32SerAsp: 3.32 ± 0.054	3.567SerGlu: 3.567 ± 0.064	3.636SerPhe: 3.636 ± 0.071	4.667SerGly: 4.667 ± 0.077	1.001SerHis: 1.001 ± 0.029	4.313SerIle: 4.313 ± 0.067	3.281SerLys: 3.281 ± 0.056	6.007SerLeu: 6.007 ± 0.084	1.455SerMet: 1.455 ± 0.04	2.568SerAsn: 2.568 ± 0.062	2.256SerPro: 2.256 ± 0.045	1.668SerGln: 1.668 ± 0.04	2.93SerArg: 2.93 ± 0.059	3.886SerSer: 3.886 ± 0.084	2.99SerThr: 2.99 ± 0.06	4.472SerVal: 4.472 ± 0.067	0.798SerTrp: 0.798 ± 0.032	2.812SerTyr: 2.812 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	3.559ThrAla: 3.559 ± 0.067	0.542ThrCys: 0.542 ± 0.024	3.04ThrAsp: 3.04 ± 0.068	3.244ThrGlu: 3.244 ± 0.064	2.513ThrPhe: 2.513 ± 0.054	4.419ThrGly: 4.419 ± 0.069	0.851ThrHis: 0.851 ± 0.035	3.99ThrIle: 3.99 ± 0.072	2.796ThrLys: 2.796 ± 0.049	5.409ThrLeu: 5.409 ± 0.091	1.106ThrMet: 1.106 ± 0.032	2.207ThrAsn: 2.207 ± 0.057	2.565ThrPro: 2.565 ± 0.059	1.412ThrGln: 1.412 ± 0.038	2.423ThrArg: 2.423 ± 0.046	3.226ThrSer: 3.226 ± 0.058	3.09ThrThr: 3.09 ± 0.067	3.941ThrVal: 3.941 ± 0.068	0.572ThrTrp: 0.572 ± 0.024	2.223ThrTyr: 2.223 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	4.367ValAla: 4.367 ± 0.066	0.889ValCys: 0.889 ± 0.034	3.696ValAsp: 3.696 ± 0.069	4.37ValGlu: 4.37 ± 0.071	3.347ValPhe: 3.347 ± 0.059	4.138ValGly: 4.138 ± 0.088	1.035ValHis: 1.035 ± 0.034	5.121ValIle: 5.121 ± 0.074	4.802ValLys: 4.802 ± 0.078	6.465ValLeu: 6.465 ± 0.094	1.797ValMet: 1.797 ± 0.048	3.226ValAsn: 3.226 ± 0.056	2.464ValPro: 2.464 ± 0.055	1.796ValGln: 1.796 ± 0.041	3.286ValArg: 3.286 ± 0.063	4.459ValSer: 4.459 ± 0.07	3.695ValThr: 3.695 ± 0.059	4.907ValVal: 4.907 ± 0.092	0.746ValTrp: 0.746 ± 0.031	2.85ValTyr: 2.85 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.619TrpAla: 0.619 ± 0.026	0.14TrpCys: 0.14 ± 0.012	0.595TrpAsp: 0.595 ± 0.026	0.766TrpGlu: 0.766 ± 0.026	0.532TrpPhe: 0.532 ± 0.024	0.963TrpGly: 0.963 ± 0.031	0.198TrpHis: 0.198 ± 0.014	0.846TrpIle: 0.846 ± 0.032	0.795TrpLys: 0.795 ± 0.028	1.203TrpLeu: 1.203 ± 0.047	0.375TrpMet: 0.375 ± 0.02	0.702TrpAsn: 0.702 ± 0.03	0.232TrpPro: 0.232 ± 0.018	0.431TrpGln: 0.431 ± 0.022	0.577TrpArg: 0.577 ± 0.028	0.611TrpSer: 0.611 ± 0.03	0.526TrpThr: 0.526 ± 0.025	0.685TrpVal: 0.685 ± 0.031	0.154TrpTrp: 0.154 ± 0.012	0.537TrpTyr: 0.537 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.831TyrAla: 2.831 ± 0.05	0.513TyrCys: 0.513 ± 0.024	2.592TyrAsp: 2.592 ± 0.057	2.484TyrGlu: 2.484 ± 0.046	2.337TyrPhe: 2.337 ± 0.052	2.901TyrGly: 2.901 ± 0.047	0.825TyrHis: 0.825 ± 0.031	2.904TyrIle: 2.904 ± 0.057	2.754TyrLys: 2.754 ± 0.055	4.182TyrLeu: 4.182 ± 0.077	1.003TyrMet: 1.003 ± 0.032	2.435TyrAsn: 2.435 ± 0.053	1.91TyrPro: 1.91 ± 0.045	1.384TyrGln: 1.384 ± 0.04	2.498TyrArg: 2.498 ± 0.05	2.776TyrSer: 2.776 ± 0.054	2.632TyrThr: 2.632 ± 0.06	2.576TyrVal: 2.576 ± 0.052	0.537TyrTrp: 0.537 ± 0.022	2.133TyrTyr: 2.133 ± 0.055	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2587 proteins (944104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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