Amino acid dipepetide frequency for Human gemycircularvirus GeTz1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.038AlaAla: 4.038 ± 1.843
0.0AlaCys: 0.0 ± 0.0
2.692AlaAsp: 2.692 ± 0.854
12.113AlaGlu: 12.113 ± 4.813
0.0AlaPhe: 0.0 ± 0.0
4.038AlaGly: 4.038 ± 2.139
0.0AlaHis: 0.0 ± 0.0
4.038AlaIle: 4.038 ± 2.496
1.346AlaLys: 1.346 ± 1.147
5.384AlaLeu: 5.384 ± 1.356
4.038AlaMet: 4.038 ± 0.538
2.692AlaAsn: 2.692 ± 0.854
1.346AlaPro: 1.346 ± 1.246
0.0AlaGln: 0.0 ± 0.0
5.384AlaArg: 5.384 ± 1.356
6.729AlaSer: 6.729 ± 2.454
2.692AlaThr: 2.692 ± 0.854
4.038AlaVal: 4.038 ± 1.236
0.0AlaTrp: 0.0 ± 0.0
2.692AlaTyr: 2.692 ± 0.854
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.346CysPhe: 1.346 ± 0.832
1.346CysGly: 1.346 ± 0.832
0.0CysHis: 0.0 ± 0.0
1.346CysIle: 1.346 ± 0.832
0.0CysLys: 0.0 ± 0.0
2.692CysLeu: 2.692 ± 1.322
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.692CysPro: 2.692 ± 0.854
1.346CysGln: 1.346 ± 0.832
1.346CysArg: 1.346 ± 0.832
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
5.384AspAsp: 5.384 ± 2.949
2.692AspGlu: 2.692 ± 0.854
2.692AspPhe: 2.692 ± 0.854
6.729AspGly: 6.729 ± 1.235
1.346AspHis: 1.346 ± 0.832
2.692AspIle: 2.692 ± 1.664
1.346AspLys: 1.346 ± 1.147
2.692AspLeu: 2.692 ± 1.171
1.346AspMet: 1.346 ± 1.246
2.692AspAsn: 2.692 ± 2.294
5.384AspPro: 5.384 ± 2.272
4.038AspGln: 4.038 ± 1.843
2.692AspArg: 2.692 ± 1.664
2.692AspSer: 2.692 ± 1.171
5.384AspThr: 5.384 ± 3.168
2.692AspVal: 2.692 ± 1.664
2.692AspTrp: 2.692 ± 1.322
4.038AspTyr: 4.038 ± 1.843
0.0AspXaa: 0.0 ± 0.0
Glu
1.346GluAla: 1.346 ± 1.147
1.346GluCys: 1.346 ± 0.832
2.692GluAsp: 2.692 ± 1.171
9.421GluGlu: 9.421 ± 2.065
4.038GluPhe: 4.038 ± 1.604
4.038GluGly: 4.038 ± 1.843
4.038GluHis: 4.038 ± 0.538
2.692GluIle: 2.692 ± 1.664
2.692GluLys: 2.692 ± 1.171
1.346GluLeu: 1.346 ± 1.246
2.692GluMet: 2.692 ± 2.491
2.692GluAsn: 2.692 ± 1.322
1.346GluPro: 1.346 ± 0.832
1.346GluGln: 1.346 ± 1.246
1.346GluArg: 1.346 ± 0.832
2.692GluSer: 2.692 ± 1.664
1.346GluThr: 1.346 ± 1.246
1.346GluVal: 1.346 ± 0.832
2.692GluTrp: 2.692 ± 1.664
1.346GluTyr: 1.346 ± 0.832
0.0GluXaa: 0.0 ± 0.0
Phe
1.346PheAla: 1.346 ± 0.832
0.0PheCys: 0.0 ± 0.0
2.692PheAsp: 2.692 ± 1.664
1.346PheGlu: 1.346 ± 1.147
0.0PhePhe: 0.0 ± 0.0
4.038PheGly: 4.038 ± 1.604
0.0PheHis: 0.0 ± 0.0
2.692PheIle: 2.692 ± 1.322
2.692PheLys: 2.692 ± 1.171
2.692PheLeu: 2.692 ± 1.664
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.346PhePro: 1.346 ± 1.147
2.692PheGln: 2.692 ± 1.171
1.346PheArg: 1.346 ± 0.832
5.384PheSer: 5.384 ± 1.926
5.384PheThr: 5.384 ± 1.356
1.346PheVal: 1.346 ± 0.832
4.038PheTrp: 4.038 ± 0.538
1.346PheTyr: 1.346 ± 0.832
0.0PheXaa: 0.0 ± 0.0
Gly
1.346GlyAla: 1.346 ± 1.147
0.0GlyCys: 0.0 ± 0.0
8.075GlyAsp: 8.075 ± 2.054
2.692GlyGlu: 2.692 ± 1.664
0.0GlyPhe: 0.0 ± 0.0
13.459GlyGly: 13.459 ± 6.044
2.692GlyHis: 2.692 ± 1.664
2.692GlyIle: 2.692 ± 1.664
6.729GlyLys: 6.729 ± 1.955
12.113GlyLeu: 12.113 ± 3.696
0.0GlyMet: 0.0 ± 0.0
5.384GlyAsn: 5.384 ± 1.356
1.346GlyPro: 1.346 ± 0.832
0.0GlyGln: 0.0 ± 0.0
6.729GlyArg: 6.729 ± 1.955
4.038GlySer: 4.038 ± 3.441
9.421GlyThr: 9.421 ± 3.973
5.384GlyVal: 5.384 ± 1.356
0.0GlyTrp: 0.0 ± 0.0
5.384GlyTyr: 5.384 ± 1.708
0.0GlyXaa: 0.0 ± 0.0
His
2.692HisAla: 2.692 ± 0.854
1.346HisCys: 1.346 ± 0.832
0.0HisAsp: 0.0 ± 0.0
1.346HisGlu: 1.346 ± 1.246
0.0HisPhe: 0.0 ± 0.0
2.692HisGly: 2.692 ± 1.171
1.346HisHis: 1.346 ± 0.832
1.346HisIle: 1.346 ± 1.147
0.0HisLys: 0.0 ± 0.0
2.692HisLeu: 2.692 ± 1.664
0.0HisMet: 0.0 ± 0.0
2.692HisAsn: 2.692 ± 1.322
1.346HisPro: 1.346 ± 0.832
1.346HisGln: 1.346 ± 0.832
2.692HisArg: 2.692 ± 1.171
0.0HisSer: 0.0 ± 0.0
2.692HisThr: 2.692 ± 0.854
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.346IleAla: 1.346 ± 1.246
1.346IleCys: 1.346 ± 1.147
1.346IleAsp: 1.346 ± 1.147
1.346IleGlu: 1.346 ± 0.832
2.692IlePhe: 2.692 ± 0.854
5.384IleGly: 5.384 ± 0.464
1.346IleHis: 1.346 ± 0.832
5.384IleIle: 5.384 ± 1.708
1.346IleLys: 1.346 ± 0.832
2.692IleLeu: 2.692 ± 1.171
2.692IleMet: 2.692 ± 1.269
1.346IleAsn: 1.346 ± 1.147
1.346IlePro: 1.346 ± 1.147
0.0IleGln: 0.0 ± 0.0
8.075IleArg: 8.075 ± 0.72
1.346IleSer: 1.346 ± 1.147
2.692IleThr: 2.692 ± 0.854
2.692IleVal: 2.692 ± 1.664
1.346IleTrp: 1.346 ± 0.832
1.346IleTyr: 1.346 ± 1.147
0.0IleXaa: 0.0 ± 0.0
Lys
1.346LysAla: 1.346 ± 1.147
0.0LysCys: 0.0 ± 0.0
4.038LysAsp: 4.038 ± 0.538
2.692LysGlu: 2.692 ± 0.854
8.075LysPhe: 8.075 ± 2.054
4.038LysGly: 4.038 ± 1.236
0.0LysHis: 0.0 ± 0.0
2.692LysIle: 2.692 ± 0.854
2.692LysLys: 2.692 ± 0.854
5.384LysLeu: 5.384 ± 2.272
1.346LysMet: 1.346 ± 1.246
0.0LysAsn: 0.0 ± 0.0
1.346LysPro: 1.346 ± 0.832
0.0LysGln: 0.0 ± 0.0
1.346LysArg: 1.346 ± 0.832
2.692LysSer: 2.692 ± 2.491
4.038LysThr: 4.038 ± 3.441
2.692LysVal: 2.692 ± 1.171
1.346LysTrp: 1.346 ± 1.147
1.346LysTyr: 1.346 ± 1.246
0.0LysXaa: 0.0 ± 0.0
Leu
2.692LeuAla: 2.692 ± 1.171
0.0LeuCys: 0.0 ± 0.0
4.038LeuAsp: 4.038 ± 1.604
4.038LeuGlu: 4.038 ± 0.538
2.692LeuPhe: 2.692 ± 1.171
9.421LeuGly: 9.421 ± 1.464
1.346LeuHis: 1.346 ± 0.832
0.0LeuIle: 0.0 ± 0.0
5.384LeuLys: 5.384 ± 2.342
2.692LeuLeu: 2.692 ± 0.854
0.0LeuMet: 0.0 ± 0.0
2.692LeuAsn: 2.692 ± 0.854
4.038LeuPro: 4.038 ± 1.604
5.384LeuGln: 5.384 ± 3.469
1.346LeuArg: 1.346 ± 1.246
10.767LeuSer: 10.767 ± 4.683
4.038LeuThr: 4.038 ± 0.538
8.075LeuVal: 8.075 ± 1.077
5.384LeuTrp: 5.384 ± 2.272
1.346LeuTyr: 1.346 ± 1.147
0.0LeuXaa: 0.0 ± 0.0
Met
2.692MetAla: 2.692 ± 1.322
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.692MetGlu: 2.692 ± 1.171
0.0MetPhe: 0.0 ± 0.0
1.346MetGly: 1.346 ± 1.246
0.0MetHis: 0.0 ± 0.0
1.346MetIle: 1.346 ± 1.246
0.0MetLys: 0.0 ± 0.0
2.692MetLeu: 2.692 ± 2.491
0.0MetMet: 0.0 ± 0.0
1.346MetAsn: 1.346 ± 1.147
0.0MetPro: 0.0 ± 0.0
1.346MetGln: 1.346 ± 1.246
1.346MetArg: 1.346 ± 1.147
2.692MetSer: 2.692 ± 1.171
1.346MetThr: 1.346 ± 1.147
2.692MetVal: 2.692 ± 0.854
1.346MetTrp: 1.346 ± 1.246
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.384AsnAla: 5.384 ± 0.464
1.346AsnCys: 1.346 ± 0.832
2.692AsnAsp: 2.692 ± 1.322
1.346AsnGlu: 1.346 ± 1.147
1.346AsnPhe: 1.346 ± 1.147
1.346AsnGly: 1.346 ± 0.832
1.346AsnHis: 1.346 ± 0.832
1.346AsnIle: 1.346 ± 1.147
1.346AsnLys: 1.346 ± 1.147
4.038AsnLeu: 4.038 ± 0.538
1.346AsnMet: 1.346 ± 1.147
5.384AsnAsn: 5.384 ± 2.949
1.346AsnPro: 1.346 ± 1.147
2.692AsnGln: 2.692 ± 2.294
0.0AsnArg: 0.0 ± 0.0
8.075AsnSer: 8.075 ± 5.371
5.384AsnThr: 5.384 ± 1.926
2.692AsnVal: 2.692 ± 1.171
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.729ProAla: 6.729 ± 0.698
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
1.346ProGlu: 1.346 ± 1.246
1.346ProPhe: 1.346 ± 1.147
2.692ProGly: 2.692 ± 1.664
1.346ProHis: 1.346 ± 1.147
0.0ProIle: 0.0 ± 0.0
0.0ProLys: 0.0 ± 0.0
1.346ProLeu: 1.346 ± 1.246
0.0ProMet: 0.0 ± 0.0
2.692ProAsn: 2.692 ± 1.171
0.0ProPro: 0.0 ± 0.0
1.346ProGln: 1.346 ± 0.832
2.692ProArg: 2.692 ± 1.664
6.729ProSer: 6.729 ± 3.022
6.729ProThr: 6.729 ± 1.416
1.346ProVal: 1.346 ± 1.147
1.346ProTrp: 1.346 ± 0.832
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
2.692GlnCys: 2.692 ± 1.664
4.038GlnAsp: 4.038 ± 3.441
2.692GlnGlu: 2.692 ± 1.664
1.346GlnPhe: 1.346 ± 0.832
2.692GlnGly: 2.692 ± 2.294
1.346GlnHis: 1.346 ± 1.147
0.0GlnIle: 0.0 ± 0.0
5.384GlnLys: 5.384 ± 3.469
0.0GlnLeu: 0.0 ± 0.0
2.692GlnMet: 2.692 ± 2.008
1.346GlnAsn: 1.346 ± 1.246
0.0GlnPro: 0.0 ± 0.0
1.346GlnGln: 1.346 ± 1.246
0.0GlnArg: 0.0 ± 0.0
2.692GlnSer: 2.692 ± 1.171
1.346GlnThr: 1.346 ± 1.246
0.0GlnVal: 0.0 ± 0.0
1.346GlnTrp: 1.346 ± 0.832
1.346GlnTyr: 1.346 ± 1.246
0.0GlnXaa: 0.0 ± 0.0
Arg
6.729ArgAla: 6.729 ± 1.235
0.0ArgCys: 0.0 ± 0.0
6.729ArgAsp: 6.729 ± 1.235
2.692ArgGlu: 2.692 ± 1.664
1.346ArgPhe: 1.346 ± 0.832
4.038ArgGly: 4.038 ± 2.139
1.346ArgHis: 1.346 ± 1.246
1.346ArgIle: 1.346 ± 1.147
1.346ArgLys: 1.346 ± 0.832
4.038ArgLeu: 4.038 ± 1.236
0.0ArgMet: 0.0 ± 0.0
4.038ArgAsn: 4.038 ± 1.236
4.038ArgPro: 4.038 ± 1.604
1.346ArgGln: 1.346 ± 1.147
6.729ArgArg: 6.729 ± 1.416
5.384ArgSer: 5.384 ± 2.272
1.346ArgThr: 1.346 ± 1.246
1.346ArgVal: 1.346 ± 1.147
4.038ArgTrp: 4.038 ± 0.538
5.384ArgTyr: 5.384 ± 0.464
0.0ArgXaa: 0.0 ± 0.0
Ser
6.729SerAla: 6.729 ± 0.698
2.692SerCys: 2.692 ± 1.171
4.038SerAsp: 4.038 ± 1.236
0.0SerGlu: 0.0 ± 0.0
6.729SerPhe: 6.729 ± 1.416
5.384SerGly: 5.384 ± 2.645
2.692SerHis: 2.692 ± 1.171
2.692SerIle: 2.692 ± 1.664
4.038SerLys: 4.038 ± 0.538
6.729SerLeu: 6.729 ± 2.683
2.692SerMet: 2.692 ± 1.171
2.692SerAsn: 2.692 ± 2.294
5.384SerPro: 5.384 ± 0.464
1.346SerGln: 1.346 ± 1.147
5.384SerArg: 5.384 ± 1.926
9.421SerSer: 9.421 ± 3.455
12.113SerThr: 12.113 ± 2.983
5.384SerVal: 5.384 ± 1.356
2.692SerTrp: 2.692 ± 1.322
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.384ThrAla: 5.384 ± 4.588
0.0ThrCys: 0.0 ± 0.0
4.038ThrAsp: 4.038 ± 1.236
0.0ThrGlu: 0.0 ± 0.0
4.038ThrPhe: 4.038 ± 0.538
4.038ThrGly: 4.038 ± 0.538
1.346ThrHis: 1.346 ± 1.246
5.384ThrIle: 5.384 ± 2.645
5.384ThrLys: 5.384 ± 1.708
5.384ThrLeu: 5.384 ± 1.356
0.0ThrMet: 0.0 ± 0.0
5.384ThrAsn: 5.384 ± 1.708
4.038ThrPro: 4.038 ± 2.299
4.038ThrGln: 4.038 ± 2.27
2.692ThrArg: 2.692 ± 1.322
12.113ThrSer: 12.113 ± 3.796
4.038ThrThr: 4.038 ± 2.139
2.692ThrVal: 2.692 ± 1.322
0.0ThrTrp: 0.0 ± 0.0
5.384ThrTyr: 5.384 ± 0.464
0.0ThrXaa: 0.0 ± 0.0
Val
4.038ValAla: 4.038 ± 1.604
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.346ValGlu: 1.346 ± 1.246
1.346ValPhe: 1.346 ± 0.832
6.729ValGly: 6.729 ± 2.697
1.346ValHis: 1.346 ± 0.832
5.384ValIle: 5.384 ± 2.949
1.346ValLys: 1.346 ± 1.147
6.729ValLeu: 6.729 ± 1.416
1.346ValMet: 1.346 ± 0.841
5.384ValAsn: 5.384 ± 1.708
0.0ValPro: 0.0 ± 0.0
2.692ValGln: 2.692 ± 1.171
4.038ValArg: 4.038 ± 2.27
1.346ValSer: 1.346 ± 0.832
1.346ValThr: 1.346 ± 0.832
2.692ValVal: 2.692 ± 0.854
1.346ValTrp: 1.346 ± 1.147
4.038ValTyr: 4.038 ± 1.843
0.0ValXaa: 0.0 ± 0.0
Trp
4.038TrpAla: 4.038 ± 2.496
1.346TrpCys: 1.346 ± 1.147
1.346TrpAsp: 1.346 ± 1.147
2.692TrpGlu: 2.692 ± 2.491
0.0TrpPhe: 0.0 ± 0.0
4.038TrpGly: 4.038 ± 2.496
1.346TrpHis: 1.346 ± 1.147
1.346TrpIle: 1.346 ± 1.246
0.0TrpLys: 0.0 ± 0.0
4.038TrpLeu: 4.038 ± 1.604
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
5.384TrpArg: 5.384 ± 1.708
1.346TrpSer: 1.346 ± 1.246
1.346TrpThr: 1.346 ± 1.147
1.346TrpVal: 1.346 ± 0.832
0.0TrpTrp: 0.0 ± 0.0
1.346TrpTyr: 1.346 ± 1.246
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.384TyrAla: 5.384 ± 0.464
0.0TyrCys: 0.0 ± 0.0
5.384TyrAsp: 5.384 ± 1.356
0.0TyrGlu: 0.0 ± 0.0
1.346TyrPhe: 1.346 ± 0.832
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
2.692TyrIle: 2.692 ± 0.854
4.038TyrLys: 4.038 ± 1.236
0.0TyrLeu: 0.0 ± 0.0
1.346TyrMet: 1.346 ± 1.147
0.0TyrAsn: 0.0 ± 0.0
1.346TyrPro: 1.346 ± 0.832
1.346TyrGln: 1.346 ± 1.147
2.692TyrArg: 2.692 ± 2.491
2.692TyrSer: 2.692 ± 1.322
2.692TyrThr: 2.692 ± 2.294
4.038TyrVal: 4.038 ± 1.236
1.346TyrTrp: 1.346 ± 0.832
2.692TyrTyr: 2.692 ± 0.854
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (744 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski