Amino acid dipepetide frequency for Luteimonas marina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.111AlaAla: 19.111 ± 0.235	1.289AlaCys: 1.289 ± 0.034	7.729AlaAsp: 7.729 ± 0.089	7.063AlaGlu: 7.063 ± 0.099	4.403AlaPhe: 4.403 ± 0.061	12.166AlaGly: 12.166 ± 0.12	2.641AlaHis: 2.641 ± 0.052	5.818AlaIle: 5.818 ± 0.071	3.32AlaLys: 3.32 ± 0.071	15.905AlaLeu: 15.905 ± 0.148	3.402AlaMet: 3.402 ± 0.06	2.737AlaAsn: 2.737 ± 0.05	6.725AlaPro: 6.725 ± 0.103	5.202AlaGln: 5.202 ± 0.069	10.647AlaArg: 10.647 ± 0.126	6.647AlaSer: 6.647 ± 0.084	6.591AlaThr: 6.591 ± 0.106	8.766AlaVal: 8.766 ± 0.1	2.24AlaTrp: 2.24 ± 0.05	2.485AlaTyr: 2.485 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.04CysAla: 1.04 ± 0.031	0.125CysCys: 0.125 ± 0.013	0.454CysAsp: 0.454 ± 0.022	0.402CysGlu: 0.402 ± 0.02	0.28CysPhe: 0.28 ± 0.017	0.882CysGly: 0.882 ± 0.03	0.226CysHis: 0.226 ± 0.015	0.321CysIle: 0.321 ± 0.018	0.155CysLys: 0.155 ± 0.012	0.786CysLeu: 0.786 ± 0.03	0.133CysMet: 0.133 ± 0.011	0.185CysAsn: 0.185 ± 0.013	0.422CysPro: 0.422 ± 0.023	0.186CysGln: 0.186 ± 0.013	0.615CysArg: 0.615 ± 0.026	0.426CysSer: 0.426 ± 0.018	0.39CysThr: 0.39 ± 0.018	0.595CysVal: 0.595 ± 0.024	0.117CysTrp: 0.117 ± 0.011	0.179CysTyr: 0.179 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	9.709AspAla: 9.709 ± 0.118	0.455AspCys: 0.455 ± 0.02	3.957AspAsp: 3.957 ± 0.065	3.633AspGlu: 3.633 ± 0.057	2.138AspPhe: 2.138 ± 0.043	6.699AspGly: 6.699 ± 0.094	1.198AspHis: 1.198 ± 0.035	2.412AspIle: 2.412 ± 0.042	1.417AspLys: 1.417 ± 0.042	5.606AspLeu: 5.606 ± 0.073	1.099AspMet: 1.099 ± 0.03	1.304AspAsn: 1.304 ± 0.039	3.889AspPro: 3.889 ± 0.065	1.427AspGln: 1.427 ± 0.036	4.568AspArg: 4.568 ± 0.066	2.476AspSer: 2.476 ± 0.045	2.693AspThr: 2.693 ± 0.051	4.415AspVal: 4.415 ± 0.062	1.19AspTrp: 1.19 ± 0.032	1.595AspTyr: 1.595 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.894GluAla: 7.894 ± 0.098	0.334GluCys: 0.334 ± 0.018	2.739GluAsp: 2.739 ± 0.053	2.376GluGlu: 2.376 ± 0.056	1.727GluPhe: 1.727 ± 0.046	4.379GluGly: 4.379 ± 0.065	1.461GluHis: 1.461 ± 0.039	2.484GluIle: 2.484 ± 0.05	1.42GluLys: 1.42 ± 0.045	5.931GluLeu: 5.931 ± 0.08	1.054GluMet: 1.054 ± 0.034	1.128GluAsn: 1.128 ± 0.032	2.685GluPro: 2.685 ± 0.054	2.34GluGln: 2.34 ± 0.045	5.572GluArg: 5.572 ± 0.075	2.516GluSer: 2.516 ± 0.043	2.646GluThr: 2.646 ± 0.048	4.015GluVal: 4.015 ± 0.068	0.741GluTrp: 0.741 ± 0.028	1.176GluTyr: 1.176 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.672PheAla: 4.672 ± 0.068	0.307PheCys: 0.307 ± 0.018	2.844PheAsp: 2.844 ± 0.052	2.073PheGlu: 2.073 ± 0.045	1.184PhePhe: 1.184 ± 0.039	3.505PheGly: 3.505 ± 0.054	0.728PheHis: 0.728 ± 0.027	1.199PheIle: 1.199 ± 0.038	0.732PheLys: 0.732 ± 0.029	3.072PheLeu: 3.072 ± 0.061	0.596PheMet: 0.596 ± 0.023	0.95PheAsn: 0.95 ± 0.03	1.48PhePro: 1.48 ± 0.032	0.849PheGln: 0.849 ± 0.026	2.397PheArg: 2.397 ± 0.047	1.907PheSer: 1.907 ± 0.042	1.581PheThr: 1.581 ± 0.038	2.607PheVal: 2.607 ± 0.046	0.49PheTrp: 0.49 ± 0.026	0.778PheTyr: 0.778 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.843GlyAla: 9.843 ± 0.121	0.759GlyCys: 0.759 ± 0.026	5.576GlyAsp: 5.576 ± 0.083	5.46GlyGlu: 5.46 ± 0.076	3.614GlyPhe: 3.614 ± 0.059	8.002GlyGly: 8.002 ± 0.112	2.13GlyHis: 2.13 ± 0.046	4.258GlyIle: 4.258 ± 0.069	2.816GlyLys: 2.816 ± 0.061	8.79GlyLeu: 8.79 ± 0.093	2.221GlyMet: 2.221 ± 0.042	2.357GlyAsn: 2.357 ± 0.051	3.205GlyPro: 3.205 ± 0.049	2.9GlyGln: 2.9 ± 0.05	6.778GlyArg: 6.778 ± 0.085	4.694GlySer: 4.694 ± 0.073	4.472GlyThr: 4.472 ± 0.071	6.573GlyVal: 6.573 ± 0.08	1.747GlyTrp: 1.747 ± 0.041	2.446GlyTyr: 2.446 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	3.214HisAla: 3.214 ± 0.057	0.252HisCys: 0.252 ± 0.017	1.411HisAsp: 1.411 ± 0.038	1.162HisGlu: 1.162 ± 0.031	0.811HisPhe: 0.811 ± 0.026	2.305HisGly: 2.305 ± 0.044	0.564HisHis: 0.564 ± 0.026	0.666HisIle: 0.666 ± 0.028	0.455HisLys: 0.455 ± 0.02	2.115HisLeu: 2.115 ± 0.041	0.389HisMet: 0.389 ± 0.018	0.473HisAsn: 0.473 ± 0.02	1.555HisPro: 1.555 ± 0.04	0.556HisGln: 0.556 ± 0.02	1.795HisArg: 1.795 ± 0.043	0.893HisSer: 0.893 ± 0.031	0.82HisThr: 0.82 ± 0.027	1.71HisVal: 1.71 ± 0.041	0.431HisTrp: 0.431 ± 0.02	0.581HisTyr: 0.581 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.504IleAla: 6.504 ± 0.079	0.276IleCys: 0.276 ± 0.015	3.52IleAsp: 3.52 ± 0.06	2.995IleGlu: 2.995 ± 0.054	1.022IlePhe: 1.022 ± 0.033	4.358IleGly: 4.358 ± 0.07	0.864IleHis: 0.864 ± 0.025	1.189IleIle: 1.189 ± 0.033	0.937IleLys: 0.937 ± 0.029	3.048IleLeu: 3.048 ± 0.052	0.517IleMet: 0.517 ± 0.022	1.06IleAsn: 1.06 ± 0.032	2.047IlePro: 2.047 ± 0.043	0.967IleGln: 0.967 ± 0.03	2.789IleArg: 2.789 ± 0.045	1.878IleSer: 1.878 ± 0.042	1.98IleThr: 1.98 ± 0.04	3.548IleVal: 3.548 ± 0.064	0.426IleTrp: 0.426 ± 0.022	0.74IleTyr: 0.74 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.203LysAla: 3.203 ± 0.068	0.126LysCys: 0.126 ± 0.012	1.381LysAsp: 1.381 ± 0.041	1.022LysGlu: 1.022 ± 0.038	0.711LysPhe: 0.711 ± 0.026	1.838LysGly: 1.838 ± 0.044	0.539LysHis: 0.539 ± 0.024	1.035LysIle: 1.035 ± 0.029	0.9LysLys: 0.9 ± 0.047	2.797LysLeu: 2.797 ± 0.052	0.505LysMet: 0.505 ± 0.024	0.557LysAsn: 0.557 ± 0.026	1.706LysPro: 1.706 ± 0.044	1.055LysGln: 1.055 ± 0.037	2.101LysArg: 2.101 ± 0.053	1.228LysSer: 1.228 ± 0.032	1.369LysThr: 1.369 ± 0.038	1.987LysVal: 1.987 ± 0.047	0.31LysTrp: 0.31 ± 0.016	0.583LysTyr: 0.583 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	15.349LeuAla: 15.349 ± 0.148	0.95LeuCys: 0.95 ± 0.028	6.961LeuAsp: 6.961 ± 0.089	5.341LeuGlu: 5.341 ± 0.077	3.478LeuPhe: 3.478 ± 0.055	8.495LeuGly: 8.495 ± 0.094	2.44LeuHis: 2.44 ± 0.051	3.286LeuIle: 3.286 ± 0.062	2.704LeuLys: 2.704 ± 0.053	11.903LeuLeu: 11.903 ± 0.156	1.952LeuMet: 1.952 ± 0.039	2.114LeuAsn: 2.114 ± 0.041	6.687LeuPro: 6.687 ± 0.074	3.828LeuGln: 3.828 ± 0.071	9.249LeuArg: 9.249 ± 0.101	5.759LeuSer: 5.759 ± 0.07	4.302LeuThr: 4.302 ± 0.063	8.409LeuVal: 8.409 ± 0.103	1.401LeuTrp: 1.401 ± 0.042	2.175LeuTyr: 2.175 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.651MetAla: 2.651 ± 0.057	0.117MetCys: 0.117 ± 0.011	1.021MetAsp: 1.021 ± 0.028	0.887MetGlu: 0.887 ± 0.03	0.616MetPhe: 0.616 ± 0.024	1.43MetGly: 1.43 ± 0.033	0.455MetHis: 0.455 ± 0.02	0.809MetIle: 0.809 ± 0.027	0.705MetLys: 0.705 ± 0.024	2.305MetLeu: 2.305 ± 0.05	0.44MetMet: 0.44 ± 0.022	0.631MetAsn: 0.631 ± 0.026	1.429MetPro: 1.429 ± 0.036	0.817MetGln: 0.817 ± 0.027	1.841MetArg: 1.841 ± 0.038	1.386MetSer: 1.386 ± 0.03	1.331MetThr: 1.331 ± 0.032	1.384MetVal: 1.384 ± 0.035	0.205MetTrp: 0.205 ± 0.015	0.319MetTyr: 0.319 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.085AsnAla: 3.085 ± 0.054	0.205AsnCys: 0.205 ± 0.015	1.393AsnAsp: 1.393 ± 0.038	1.053AsnGlu: 1.053 ± 0.033	0.781AsnPhe: 0.781 ± 0.031	2.082AsnGly: 2.082 ± 0.047	0.505AsnHis: 0.505 ± 0.02	0.994AsnIle: 0.994 ± 0.04	0.52AsnLys: 0.52 ± 0.024	2.338AsnLeu: 2.338 ± 0.052	0.4AsnMet: 0.4 ± 0.019	0.569AsnAsn: 0.569 ± 0.026	1.704AsnPro: 1.704 ± 0.036	0.642AsnGln: 0.642 ± 0.027	1.766AsnArg: 1.766 ± 0.039	0.961AsnSer: 0.961 ± 0.029	1.157AsnThr: 1.157 ± 0.038	1.756AsnVal: 1.756 ± 0.041	0.378AsnTrp: 0.378 ± 0.02	0.657AsnTyr: 0.657 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	7.828ProAla: 7.828 ± 0.111	0.339ProCys: 0.339 ± 0.017	3.939ProAsp: 3.939 ± 0.066	3.636ProGlu: 3.636 ± 0.064	1.639ProPhe: 1.639 ± 0.032	5.216ProGly: 5.216 ± 0.077	1.062ProHis: 1.062 ± 0.032	1.854ProIle: 1.854 ± 0.035	1.305ProLys: 1.305 ± 0.036	5.51ProLeu: 5.51 ± 0.078	1.252ProMet: 1.252 ± 0.034	1.105ProAsn: 1.105 ± 0.035	3.322ProPro: 3.322 ± 0.086	1.984ProGln: 1.984 ± 0.044	3.763ProArg: 3.763 ± 0.062	2.663ProSer: 2.663 ± 0.052	2.378ProThr: 2.378 ± 0.052	4.32ProVal: 4.32 ± 0.065	0.9ProTrp: 0.9 ± 0.032	1.204ProTyr: 1.204 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.2GlnAla: 5.2 ± 0.071	0.229GlnCys: 0.229 ± 0.013	1.574GlnAsp: 1.574 ± 0.036	1.356GlnGlu: 1.356 ± 0.045	1.054GlnPhe: 1.054 ± 0.034	2.561GlnGly: 2.561 ± 0.049	0.725GlnHis: 0.725 ± 0.024	1.298GlnIle: 1.298 ± 0.033	0.765GlnLys: 0.765 ± 0.024	3.632GlnLeu: 3.632 ± 0.063	0.664GlnMet: 0.664 ± 0.022	0.609GlnAsn: 0.609 ± 0.027	2.143GlnPro: 2.143 ± 0.048	1.558GlnGln: 1.558 ± 0.042	3.372GlnArg: 3.372 ± 0.059	1.598GlnSer: 1.598 ± 0.039	1.347GlnThr: 1.347 ± 0.033	2.861GlnVal: 2.861 ± 0.051	0.591GlnTrp: 0.591 ± 0.024	0.696GlnTyr: 0.696 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	9.455ArgAla: 9.455 ± 0.113	0.543ArgCys: 0.543 ± 0.025	5.109ArgAsp: 5.109 ± 0.073	5.256ArgGlu: 5.256 ± 0.08	3.034ArgPhe: 3.034 ± 0.055	5.996ArgGly: 5.996 ± 0.079	2.181ArgHis: 2.181 ± 0.047	4.235ArgIle: 4.235 ± 0.067	1.996ArgLys: 1.996 ± 0.048	8.965ArgLeu: 8.965 ± 0.102	1.992ArgMet: 1.992 ± 0.038	1.968ArgAsn: 1.968 ± 0.043	3.887ArgPro: 3.887 ± 0.059	2.87ArgGln: 2.87 ± 0.057	7.004ArgArg: 7.004 ± 0.099	3.733ArgSer: 3.733 ± 0.06	3.512ArgThr: 3.512 ± 0.062	5.647ArgVal: 5.647 ± 0.083	1.414ArgTrp: 1.414 ± 0.04	2.198ArgTyr: 2.198 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.979SerAla: 5.979 ± 0.074	0.389SerCys: 0.389 ± 0.019	2.786SerAsp: 2.786 ± 0.051	2.37SerGlu: 2.37 ± 0.044	1.803SerPhe: 1.803 ± 0.044	5.285SerGly: 5.285 ± 0.079	1.025SerHis: 1.025 ± 0.034	2.169SerIle: 2.169 ± 0.052	1.258SerLys: 1.258 ± 0.034	5.221SerLeu: 5.221 ± 0.069	1.022SerMet: 1.022 ± 0.031	1.238SerAsn: 1.238 ± 0.036	2.915SerPro: 2.915 ± 0.061	1.565SerGln: 1.565 ± 0.041	3.84SerArg: 3.84 ± 0.064	2.673SerSer: 2.673 ± 0.061	2.588SerThr: 2.588 ± 0.05	3.517SerVal: 3.517 ± 0.06	0.781SerTrp: 0.781 ± 0.031	1.187SerTyr: 1.187 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.747ThrAla: 5.747 ± 0.09	0.342ThrCys: 0.342 ± 0.022	2.424ThrAsp: 2.424 ± 0.05	2.085ThrGlu: 2.085 ± 0.047	1.502ThrPhe: 1.502 ± 0.047	4.62ThrGly: 4.62 ± 0.08	1.029ThrHis: 1.029 ± 0.033	2.13ThrIle: 2.13 ± 0.041	0.88ThrLys: 0.88 ± 0.03	5.955ThrLeu: 5.955 ± 0.088	0.917ThrMet: 0.917 ± 0.032	0.965ThrAsn: 0.965 ± 0.036	3.365ThrPro: 3.365 ± 0.051	1.415ThrGln: 1.415 ± 0.033	3.523ThrArg: 3.523 ± 0.055	2.154ThrSer: 2.154 ± 0.054	2.421ThrThr: 2.421 ± 0.055	3.86ThrVal: 3.86 ± 0.062	0.678ThrTrp: 0.678 ± 0.028	0.987ThrTyr: 0.987 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	10.149ValAla: 10.149 ± 0.106	0.576ValCys: 0.576 ± 0.026	4.852ValAsp: 4.852 ± 0.073	4.707ValGlu: 4.707 ± 0.074	2.717ValPhe: 2.717 ± 0.056	5.702ValGly: 5.702 ± 0.086	1.55ValHis: 1.55 ± 0.036	2.97ValIle: 2.97 ± 0.064	1.748ValLys: 1.748 ± 0.051	8.27ValLeu: 8.27 ± 0.1	1.414ValMet: 1.414 ± 0.041	1.899ValAsn: 1.899 ± 0.047	4.104ValPro: 4.104 ± 0.072	2.301ValGln: 2.301 ± 0.044	5.673ValArg: 5.673 ± 0.078	3.998ValSer: 3.998 ± 0.054	3.502ValThr: 3.502 ± 0.065	6.445ValVal: 6.445 ± 0.091	0.894ValTrp: 0.894 ± 0.03	1.531ValTyr: 1.531 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.339TrpAla: 1.339 ± 0.039	0.145TrpCys: 0.145 ± 0.011	0.738TrpAsp: 0.738 ± 0.025	0.58TrpGlu: 0.58 ± 0.022	0.58TrpPhe: 0.58 ± 0.025	0.951TrpGly: 0.951 ± 0.034	0.374TrpHis: 0.374 ± 0.019	0.79TrpIle: 0.79 ± 0.029	0.476TrpLys: 0.476 ± 0.02	2.306TrpLeu: 2.306 ± 0.055	0.423TrpMet: 0.423 ± 0.02	0.513TrpAsn: 0.513 ± 0.023	0.843TrpPro: 0.843 ± 0.029	0.687TrpGln: 0.687 ± 0.024	1.585TrpArg: 1.585 ± 0.039	0.893TrpSer: 0.893 ± 0.031	0.846TrpThr: 0.846 ± 0.028	0.89TrpVal: 0.89 ± 0.029	0.345TrpTrp: 0.345 ± 0.02	0.364TrpTyr: 0.364 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.916TyrAla: 2.916 ± 0.057	0.164TyrCys: 0.164 ± 0.014	1.474TyrAsp: 1.474 ± 0.043	1.158TyrGlu: 1.158 ± 0.038	0.857TyrPhe: 0.857 ± 0.028	2.17TyrGly: 2.17 ± 0.047	0.459TyrHis: 0.459 ± 0.02	0.746TyrIle: 0.746 ± 0.029	0.446TyrLys: 0.446 ± 0.019	2.329TyrLeu: 2.329 ± 0.049	0.384TyrMet: 0.384 ± 0.02	0.582TyrAsn: 0.582 ± 0.027	1.108TyrPro: 1.108 ± 0.032	0.684TyrGln: 0.684 ± 0.025	2.117TyrArg: 2.117 ± 0.047	1.127TyrSer: 1.127 ± 0.037	1.074TyrThr: 1.074 ± 0.033	1.696TyrVal: 1.696 ± 0.036	0.389TyrTrp: 0.389 ± 0.017	0.619TyrTyr: 0.619 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3401 proteins (1148263 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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