Amino acid dipepetide frequency for Staphylococcus virus 69

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.68AlaAla: 1.68 ± 0.497
0.292AlaCys: 0.292 ± 0.15
3.359AlaAsp: 3.359 ± 0.462
3.724AlaGlu: 3.724 ± 0.455
2.702AlaPhe: 2.702 ± 0.434
2.921AlaGly: 2.921 ± 0.401
1.314AlaHis: 1.314 ± 0.279
4.747AlaIle: 4.747 ± 1.053
4.528AlaLys: 4.528 ± 0.662
4.235AlaLeu: 4.235 ± 0.723
1.534AlaMet: 1.534 ± 0.379
4.016AlaAsn: 4.016 ± 0.469
1.607AlaPro: 1.607 ± 0.394
2.191AlaGln: 2.191 ± 0.397
3.359AlaArg: 3.359 ± 0.52
3.651AlaSer: 3.651 ± 0.671
4.235AlaThr: 4.235 ± 0.674
2.921AlaVal: 2.921 ± 0.515
0.876AlaTrp: 0.876 ± 0.316
2.775AlaTyr: 2.775 ± 0.375
0.0AlaXaa: 0.0 ± 0.0
Cys
0.146CysAla: 0.146 ± 0.091
0.0CysCys: 0.0 ± 0.0
0.146CysAsp: 0.146 ± 0.09
0.584CysGlu: 0.584 ± 0.243
0.438CysPhe: 0.438 ± 0.178
0.365CysGly: 0.365 ± 0.137
0.073CysHis: 0.073 ± 0.076
0.438CysIle: 0.438 ± 0.221
0.511CysLys: 0.511 ± 0.189
0.584CysLeu: 0.584 ± 0.254
0.146CysMet: 0.146 ± 0.094
0.146CysAsn: 0.146 ± 0.108
0.292CysPro: 0.292 ± 0.155
0.365CysGln: 0.365 ± 0.157
0.438CysArg: 0.438 ± 0.192
0.219CysSer: 0.219 ± 0.159
0.438CysThr: 0.438 ± 0.179
0.146CysVal: 0.146 ± 0.107
0.073CysTrp: 0.073 ± 0.075
0.292CysTyr: 0.292 ± 0.15
0.0CysXaa: 0.0 ± 0.0
Asp
3.505AspAla: 3.505 ± 0.583
0.657AspCys: 0.657 ± 0.203
4.893AspAsp: 4.893 ± 0.965
5.769AspGlu: 5.769 ± 1.048
3.87AspPhe: 3.87 ± 0.575
3.505AspGly: 3.505 ± 0.544
0.292AspHis: 0.292 ± 0.183
4.674AspIle: 4.674 ± 0.64
5.842AspLys: 5.842 ± 0.783
5.331AspLeu: 5.331 ± 0.826
1.972AspMet: 1.972 ± 0.383
3.943AspAsn: 3.943 ± 0.446
1.095AspPro: 1.095 ± 0.275
1.241AspGln: 1.241 ± 0.328
1.972AspArg: 1.972 ± 0.415
3.651AspSer: 3.651 ± 0.538
3.14AspThr: 3.14 ± 0.529
4.235AspVal: 4.235 ± 0.504
0.584AspTrp: 0.584 ± 0.171
2.629AspTyr: 2.629 ± 0.542
0.0AspXaa: 0.0 ± 0.0
Glu
5.477GluAla: 5.477 ± 0.723
0.438GluCys: 0.438 ± 0.162
3.505GluAsp: 3.505 ± 0.599
5.404GluGlu: 5.404 ± 0.674
3.14GluPhe: 3.14 ± 0.435
3.359GluGly: 3.359 ± 0.587
1.534GluHis: 1.534 ± 0.324
5.696GluIle: 5.696 ± 0.803
5.331GluLys: 5.331 ± 0.771
6.718GluLeu: 6.718 ± 0.758
1.826GluMet: 1.826 ± 0.352
4.528GluAsn: 4.528 ± 0.548
1.972GluPro: 1.972 ± 0.319
3.943GluGln: 3.943 ± 0.605
3.432GluArg: 3.432 ± 0.643
4.162GluSer: 4.162 ± 0.522
3.505GluThr: 3.505 ± 0.557
4.893GluVal: 4.893 ± 0.705
0.73GluTrp: 0.73 ± 0.232
5.112GluTyr: 5.112 ± 0.705
0.0GluXaa: 0.0 ± 0.0
Phe
2.118PheAla: 2.118 ± 0.345
0.365PheCys: 0.365 ± 0.151
3.578PheAsp: 3.578 ± 0.565
3.87PheGlu: 3.87 ± 0.567
1.46PhePhe: 1.46 ± 0.285
2.921PheGly: 2.921 ± 0.424
0.73PheHis: 0.73 ± 0.245
3.14PheIle: 3.14 ± 0.441
4.016PheLys: 4.016 ± 0.54
2.483PheLeu: 2.483 ± 0.365
1.314PheMet: 1.314 ± 0.319
3.651PheAsn: 3.651 ± 0.452
0.803PhePro: 0.803 ± 0.265
1.314PheGln: 1.314 ± 0.367
1.387PheArg: 1.387 ± 0.334
2.702PheSer: 2.702 ± 0.439
3.14PheThr: 3.14 ± 0.463
2.629PheVal: 2.629 ± 0.538
0.219PheTrp: 0.219 ± 0.127
1.68PheTyr: 1.68 ± 0.286
0.0PheXaa: 0.0 ± 0.0
Gly
2.775GlyAla: 2.775 ± 0.58
0.365GlyCys: 0.365 ± 0.166
3.359GlyAsp: 3.359 ± 0.481
3.067GlyGlu: 3.067 ± 0.475
2.264GlyPhe: 2.264 ± 0.414
3.213GlyGly: 3.213 ± 0.546
1.095GlyHis: 1.095 ± 0.332
4.308GlyIle: 4.308 ± 0.545
4.966GlyLys: 4.966 ± 0.761
5.769GlyLeu: 5.769 ± 0.791
1.314GlyMet: 1.314 ± 0.292
3.213GlyAsn: 3.213 ± 0.479
0.511GlyPro: 0.511 ± 0.232
1.387GlyGln: 1.387 ± 0.299
1.826GlyArg: 1.826 ± 0.385
2.775GlySer: 2.775 ± 0.541
3.87GlyThr: 3.87 ± 0.556
4.016GlyVal: 4.016 ± 0.551
1.095GlyTrp: 1.095 ± 0.37
3.286GlyTyr: 3.286 ± 0.495
0.0GlyXaa: 0.0 ± 0.0
His
1.241HisAla: 1.241 ± 0.333
0.219HisCys: 0.219 ± 0.14
1.168HisAsp: 1.168 ± 0.246
1.095HisGlu: 1.095 ± 0.334
1.022HisPhe: 1.022 ± 0.295
1.241HisGly: 1.241 ± 0.286
0.584HisHis: 0.584 ± 0.22
1.095HisIle: 1.095 ± 0.291
0.511HisLys: 0.511 ± 0.223
1.46HisLeu: 1.46 ± 0.418
0.438HisMet: 0.438 ± 0.204
1.314HisAsn: 1.314 ± 0.315
0.657HisPro: 0.657 ± 0.174
0.803HisGln: 0.803 ± 0.243
0.292HisArg: 0.292 ± 0.124
1.387HisSer: 1.387 ± 0.298
0.657HisThr: 0.657 ± 0.225
1.387HisVal: 1.387 ± 0.334
0.073HisTrp: 0.073 ± 0.071
0.73HisTyr: 0.73 ± 0.331
0.0HisXaa: 0.0 ± 0.0
Ile
5.696IleAla: 5.696 ± 0.804
0.219IleCys: 0.219 ± 0.123
5.477IleAsp: 5.477 ± 0.555
5.915IleGlu: 5.915 ± 0.738
2.921IlePhe: 2.921 ± 0.556
4.235IleGly: 4.235 ± 0.502
1.241IleHis: 1.241 ± 0.261
4.455IleIle: 4.455 ± 0.672
7.375IleLys: 7.375 ± 0.743
5.039IleLeu: 5.039 ± 0.553
1.826IleMet: 1.826 ± 0.37
4.747IleAsn: 4.747 ± 0.621
2.41IlePro: 2.41 ± 0.396
2.045IleGln: 2.045 ± 0.468
3.359IleArg: 3.359 ± 0.519
3.432IleSer: 3.432 ± 0.488
5.55IleThr: 5.55 ± 0.718
3.943IleVal: 3.943 ± 0.619
1.168IleTrp: 1.168 ± 0.606
2.921IleTyr: 2.921 ± 0.485
0.0IleXaa: 0.0 ± 0.0
Lys
5.769LysAla: 5.769 ± 0.689
0.292LysCys: 0.292 ± 0.183
5.842LysAsp: 5.842 ± 0.707
7.083LysGlu: 7.083 ± 0.848
3.505LysPhe: 3.505 ± 0.524
4.674LysGly: 4.674 ± 0.602
1.972LysHis: 1.972 ± 0.411
6.134LysIle: 6.134 ± 0.681
9.566LysLys: 9.566 ± 0.948
7.083LysLeu: 7.083 ± 0.723
2.337LysMet: 2.337 ± 0.414
5.112LysAsn: 5.112 ± 0.629
2.629LysPro: 2.629 ± 0.503
4.455LysGln: 4.455 ± 0.621
4.381LysArg: 4.381 ± 0.588
4.747LysSer: 4.747 ± 0.588
4.528LysThr: 4.528 ± 0.569
6.499LysVal: 6.499 ± 0.674
0.511LysTrp: 0.511 ± 0.177
4.528LysTyr: 4.528 ± 0.711
0.0LysXaa: 0.0 ± 0.0
Leu
3.505LeuAla: 3.505 ± 0.571
0.365LeuCys: 0.365 ± 0.177
4.162LeuAsp: 4.162 ± 0.579
5.696LeuGlu: 5.696 ± 0.708
3.505LeuPhe: 3.505 ± 0.507
3.724LeuGly: 3.724 ± 0.483
1.387LeuHis: 1.387 ± 0.37
4.601LeuIle: 4.601 ± 0.475
7.668LeuLys: 7.668 ± 0.565
6.864LeuLeu: 6.864 ± 0.767
2.191LeuMet: 2.191 ± 0.429
6.718LeuAsn: 6.718 ± 0.752
2.775LeuPro: 2.775 ± 0.452
3.797LeuGln: 3.797 ± 0.543
4.016LeuArg: 4.016 ± 0.785
5.258LeuSer: 5.258 ± 0.574
5.112LeuThr: 5.112 ± 0.64
4.82LeuVal: 4.82 ± 0.719
0.949LeuTrp: 0.949 ± 0.285
3.14LeuTyr: 3.14 ± 0.466
0.0LeuXaa: 0.0 ± 0.0
Met
1.022MetAla: 1.022 ± 0.295
0.219MetCys: 0.219 ± 0.126
0.949MetAsp: 0.949 ± 0.224
1.899MetGlu: 1.899 ± 0.441
0.73MetPhe: 0.73 ± 0.2
1.022MetGly: 1.022 ± 0.335
0.438MetHis: 0.438 ± 0.211
1.46MetIle: 1.46 ± 0.29
2.629MetLys: 2.629 ± 0.463
2.921MetLeu: 2.921 ± 0.358
0.949MetMet: 0.949 ± 0.266
1.826MetAsn: 1.826 ± 0.347
0.876MetPro: 0.876 ± 0.246
1.68MetGln: 1.68 ± 0.435
1.095MetArg: 1.095 ± 0.297
1.753MetSer: 1.753 ± 0.359
2.556MetThr: 2.556 ± 0.513
1.022MetVal: 1.022 ± 0.258
0.438MetTrp: 0.438 ± 0.155
1.095MetTyr: 1.095 ± 0.265
0.0MetXaa: 0.0 ± 0.0
Asn
4.747AsnAla: 4.747 ± 0.796
0.292AsnCys: 0.292 ± 0.147
4.747AsnAsp: 4.747 ± 0.706
5.404AsnGlu: 5.404 ± 0.549
3.359AsnPhe: 3.359 ± 0.578
4.747AsnGly: 4.747 ± 0.709
0.949AsnHis: 0.949 ± 0.262
4.381AsnIle: 4.381 ± 0.551
6.718AsnLys: 6.718 ± 0.662
5.112AsnLeu: 5.112 ± 0.657
2.191AsnMet: 2.191 ± 0.388
4.308AsnAsn: 4.308 ± 0.689
2.702AsnPro: 2.702 ± 0.537
2.483AsnGln: 2.483 ± 0.388
2.483AsnArg: 2.483 ± 0.342
2.41AsnSer: 2.41 ± 0.412
3.797AsnThr: 3.797 ± 0.515
4.308AsnVal: 4.308 ± 0.441
0.803AsnTrp: 0.803 ± 0.209
2.556AsnTyr: 2.556 ± 0.508
0.0AsnXaa: 0.0 ± 0.0
Pro
1.168ProAla: 1.168 ± 0.316
0.219ProCys: 0.219 ± 0.132
1.387ProAsp: 1.387 ± 0.266
1.46ProGlu: 1.46 ± 0.266
1.168ProPhe: 1.168 ± 0.278
1.68ProGly: 1.68 ± 0.431
0.511ProHis: 0.511 ± 0.176
2.191ProIle: 2.191 ± 0.367
3.067ProLys: 3.067 ± 0.541
1.387ProLeu: 1.387 ± 0.293
1.022ProMet: 1.022 ± 0.276
2.337ProAsn: 2.337 ± 0.372
0.584ProPro: 0.584 ± 0.285
1.241ProGln: 1.241 ± 0.302
1.241ProArg: 1.241 ± 0.297
1.607ProSer: 1.607 ± 0.389
1.972ProThr: 1.972 ± 0.377
2.118ProVal: 2.118 ± 0.437
0.073ProTrp: 0.073 ± 0.081
1.168ProTyr: 1.168 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
2.775GlnAla: 2.775 ± 0.516
0.657GlnCys: 0.657 ± 0.238
2.191GlnAsp: 2.191 ± 0.383
2.775GlnGlu: 2.775 ± 0.639
1.534GlnPhe: 1.534 ± 0.358
1.972GlnGly: 1.972 ± 0.293
0.584GlnHis: 0.584 ± 0.169
2.848GlnIle: 2.848 ± 0.36
3.286GlnLys: 3.286 ± 0.496
3.14GlnLeu: 3.14 ± 0.483
1.168GlnMet: 1.168 ± 0.342
2.118GlnAsn: 2.118 ± 0.398
1.826GlnPro: 1.826 ± 0.442
1.899GlnGln: 1.899 ± 0.441
1.46GlnArg: 1.46 ± 0.288
2.556GlnSer: 2.556 ± 0.373
2.191GlnThr: 2.191 ± 0.353
1.899GlnVal: 1.899 ± 0.419
0.438GlnTrp: 0.438 ± 0.186
1.241GlnTyr: 1.241 ± 0.349
0.0GlnXaa: 0.0 ± 0.0
Arg
1.607ArgAla: 1.607 ± 0.367
0.292ArgCys: 0.292 ± 0.153
2.264ArgAsp: 2.264 ± 0.401
3.505ArgGlu: 3.505 ± 0.472
1.826ArgPhe: 1.826 ± 0.438
2.191ArgGly: 2.191 ± 0.402
1.022ArgHis: 1.022 ± 0.28
3.14ArgIle: 3.14 ± 0.512
4.089ArgLys: 4.089 ± 0.577
3.943ArgLeu: 3.943 ± 0.472
0.657ArgMet: 0.657 ± 0.231
3.213ArgAsn: 3.213 ± 0.516
0.876ArgPro: 0.876 ± 0.249
1.68ArgGln: 1.68 ± 0.355
1.826ArgArg: 1.826 ± 0.42
2.191ArgSer: 2.191 ± 0.321
1.826ArgThr: 1.826 ± 0.405
2.045ArgVal: 2.045 ± 0.489
0.584ArgTrp: 0.584 ± 0.258
2.264ArgTyr: 2.264 ± 0.489
0.0ArgXaa: 0.0 ± 0.0
Ser
3.797SerAla: 3.797 ± 0.669
0.219SerCys: 0.219 ± 0.145
4.381SerAsp: 4.381 ± 0.687
3.067SerGlu: 3.067 ± 0.422
2.264SerPhe: 2.264 ± 0.405
3.505SerGly: 3.505 ± 0.657
1.095SerHis: 1.095 ± 0.322
5.769SerIle: 5.769 ± 0.737
4.893SerLys: 4.893 ± 0.498
4.235SerLeu: 4.235 ± 0.553
1.534SerMet: 1.534 ± 0.315
4.089SerAsn: 4.089 ± 0.456
1.095SerPro: 1.095 ± 0.34
1.68SerGln: 1.68 ± 0.373
2.264SerArg: 2.264 ± 0.316
3.432SerSer: 3.432 ± 0.472
3.943SerThr: 3.943 ± 0.448
3.14SerVal: 3.14 ± 0.573
0.292SerTrp: 0.292 ± 0.139
2.045SerTyr: 2.045 ± 0.376
0.0SerXaa: 0.0 ± 0.0
Thr
3.651ThrAla: 3.651 ± 0.571
0.073ThrCys: 0.073 ± 0.081
3.943ThrAsp: 3.943 ± 0.632
4.601ThrGlu: 4.601 ± 0.519
2.848ThrPhe: 2.848 ± 0.461
3.651ThrGly: 3.651 ± 0.528
0.876ThrHis: 0.876 ± 0.225
5.696ThrIle: 5.696 ± 1.143
5.55ThrLys: 5.55 ± 0.632
4.674ThrLeu: 4.674 ± 0.559
0.949ThrMet: 0.949 ± 0.309
3.797ThrAsn: 3.797 ± 0.657
1.826ThrPro: 1.826 ± 0.403
2.702ThrGln: 2.702 ± 0.516
2.191ThrArg: 2.191 ± 0.314
3.651ThrSer: 3.651 ± 0.693
3.578ThrThr: 3.578 ± 0.712
4.308ThrVal: 4.308 ± 0.755
0.803ThrTrp: 0.803 ± 0.265
2.045ThrTyr: 2.045 ± 0.383
0.0ThrXaa: 0.0 ± 0.0
Val
3.14ValAla: 3.14 ± 0.895
0.438ValCys: 0.438 ± 0.142
4.455ValAsp: 4.455 ± 0.637
5.404ValGlu: 5.404 ± 0.704
2.191ValPhe: 2.191 ± 0.498
2.41ValGly: 2.41 ± 0.565
0.73ValHis: 0.73 ± 0.213
5.331ValIle: 5.331 ± 0.542
5.258ValLys: 5.258 ± 0.549
5.112ValLeu: 5.112 ± 0.669
1.826ValMet: 1.826 ± 0.356
4.893ValAsn: 4.893 ± 0.523
1.899ValPro: 1.899 ± 0.476
1.387ValGln: 1.387 ± 0.329
1.826ValArg: 1.826 ± 0.411
3.797ValSer: 3.797 ± 0.687
3.286ValThr: 3.286 ± 0.577
4.528ValVal: 4.528 ± 0.615
1.095ValTrp: 1.095 ± 0.368
2.775ValTyr: 2.775 ± 0.541
0.0ValXaa: 0.0 ± 0.0
Trp
0.73TrpAla: 0.73 ± 0.302
0.073TrpCys: 0.073 ± 0.075
0.292TrpAsp: 0.292 ± 0.141
0.511TrpGlu: 0.511 ± 0.182
0.365TrpPhe: 0.365 ± 0.151
0.803TrpGly: 0.803 ± 0.35
0.146TrpHis: 0.146 ± 0.094
0.73TrpIle: 0.73 ± 0.265
0.949TrpLys: 0.949 ± 0.247
0.73TrpLeu: 0.73 ± 0.216
0.219TrpMet: 0.219 ± 0.133
1.826TrpAsn: 1.826 ± 0.931
0.146TrpPro: 0.146 ± 0.104
0.584TrpGln: 0.584 ± 0.21
0.365TrpArg: 0.365 ± 0.157
0.803TrpSer: 0.803 ± 0.299
1.022TrpThr: 1.022 ± 0.318
0.657TrpVal: 0.657 ± 0.288
0.0TrpTrp: 0.0 ± 0.0
0.657TrpTyr: 0.657 ± 0.226
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.118TyrAla: 2.118 ± 0.406
0.146TyrCys: 0.146 ± 0.097
2.702TyrAsp: 2.702 ± 0.481
3.87TyrGlu: 3.87 ± 0.632
2.41TyrPhe: 2.41 ± 0.494
2.337TyrGly: 2.337 ± 0.453
0.803TyrHis: 0.803 ± 0.296
3.14TyrIle: 3.14 ± 0.508
4.893TyrLys: 4.893 ± 0.702
3.432TyrLeu: 3.432 ± 0.607
1.095TyrMet: 1.095 ± 0.299
2.702TyrAsn: 2.702 ± 0.48
1.022TyrPro: 1.022 ± 0.302
1.68TyrGln: 1.68 ± 0.362
1.826TyrArg: 1.826 ± 0.369
2.629TyrSer: 2.629 ± 0.493
3.067TyrThr: 3.067 ± 0.442
2.264TyrVal: 2.264 ± 0.396
0.803TyrTrp: 0.803 ± 0.239
1.972TyrTyr: 1.972 ± 0.442
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 76 proteins (13695 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski