Amino acid dipepetide frequency for Tolypothrix campylonemoides VB511288

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.029AlaAla: 9.029 ± 0.114	0.863AlaCys: 0.863 ± 0.022	4.383AlaAsp: 4.383 ± 0.056	5.432AlaGlu: 5.432 ± 0.057	3.064AlaPhe: 3.064 ± 0.041	6.352AlaGly: 6.352 ± 0.074	1.766AlaHis: 1.766 ± 0.039	6.148AlaIle: 6.148 ± 0.056	3.948AlaLys: 3.948 ± 0.045	9.394AlaLeu: 9.394 ± 0.085	1.74AlaMet: 1.74 ± 0.032	3.014AlaAsn: 3.014 ± 0.045	3.172AlaPro: 3.172 ± 0.041	4.649AlaGln: 4.649 ± 0.058	5.108AlaArg: 5.108 ± 0.077	4.999AlaSer: 4.999 ± 0.056	4.645AlaThr: 4.645 ± 0.055	6.742AlaVal: 6.742 ± 0.075	1.059AlaTrp: 1.059 ± 0.028	2.308AlaTyr: 2.308 ± 0.035	0.002AlaXaa: 0.002 ± 0.001
Cys	0.731CysAla: 0.731 ± 0.018	0.164CysCys: 0.164 ± 0.009	0.548CysAsp: 0.548 ± 0.015	0.536CysGlu: 0.536 ± 0.015	0.385CysPhe: 0.385 ± 0.013	0.823CysGly: 0.823 ± 0.019	0.259CysHis: 0.259 ± 0.011	0.549CysIle: 0.549 ± 0.015	0.366CysLys: 0.366 ± 0.013	1.107CysLeu: 1.107 ± 0.027	0.162CysMet: 0.162 ± 0.009	0.353CysAsn: 0.353 ± 0.013	0.518CysPro: 0.518 ± 0.019	0.517CysGln: 0.517 ± 0.014	0.559CysArg: 0.559 ± 0.017	0.612CysSer: 0.612 ± 0.017	0.494CysThr: 0.494 ± 0.015	0.643CysVal: 0.643 ± 0.016	0.146CysTrp: 0.146 ± 0.009	0.333CysTyr: 0.333 ± 0.014	0.0CysXaa: 0.0 ± 0.001
Asp	4.362AspAla: 4.362 ± 0.052	0.485AspCys: 0.485 ± 0.014	2.363AspAsp: 2.363 ± 0.039	3.19AspGlu: 3.19 ± 0.04	2.226AspPhe: 2.226 ± 0.032	3.505AspGly: 3.505 ± 0.049	0.861AspHis: 0.861 ± 0.023	3.135AspIle: 3.135 ± 0.038	2.296AspLys: 2.296 ± 0.039	5.27AspLeu: 5.27 ± 0.048	0.745AspMet: 0.745 ± 0.021	1.832AspAsn: 1.832 ± 0.028	2.246AspPro: 2.246 ± 0.038	1.76AspGln: 1.76 ± 0.031	3.356AspArg: 3.356 ± 0.055	2.694AspSer: 2.694 ± 0.033	2.398AspThr: 2.398 ± 0.032	3.463AspVal: 3.463 ± 0.046	0.845AspTrp: 0.845 ± 0.02	1.728AspTyr: 1.728 ± 0.036	0.001AspXaa: 0.001 ± 0.001
Glu	5.833GluAla: 5.833 ± 0.062	0.496GluCys: 0.496 ± 0.015	2.756GluAsp: 2.756 ± 0.036	4.253GluGlu: 4.253 ± 0.059	2.424GluPhe: 2.424 ± 0.034	3.29GluGly: 3.29 ± 0.039	1.287GluHis: 1.287 ± 0.028	4.453GluIle: 4.453 ± 0.044	3.434GluLys: 3.434 ± 0.049	6.98GluLeu: 6.98 ± 0.068	1.259GluMet: 1.259 ± 0.025	2.575GluAsn: 2.575 ± 0.042	2.609GluPro: 2.609 ± 0.041	3.833GluGln: 3.833 ± 0.052	4.317GluArg: 4.317 ± 0.058	3.157GluSer: 3.157 ± 0.045	3.215GluThr: 3.215 ± 0.043	4.688GluVal: 4.688 ± 0.054	0.767GluTrp: 0.767 ± 0.024	1.847GluTyr: 1.847 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.176PheAla: 3.176 ± 0.039	0.518PheCys: 0.518 ± 0.016	2.218PheAsp: 2.218 ± 0.035	2.17PheGlu: 2.17 ± 0.035	1.653PhePhe: 1.653 ± 0.031	2.926PheGly: 2.926 ± 0.046	0.758PheHis: 0.758 ± 0.017	2.174PheIle: 2.174 ± 0.033	1.547PheLys: 1.547 ± 0.03	3.932PheLeu: 3.932 ± 0.048	0.68PheMet: 0.68 ± 0.018	1.582PheAsn: 1.582 ± 0.029	1.734PhePro: 1.734 ± 0.027	1.702PheGln: 1.702 ± 0.029	1.838PheArg: 1.838 ± 0.035	2.699PheSer: 2.699 ± 0.046	2.119PheThr: 2.119 ± 0.033	2.61PheVal: 2.61 ± 0.038	0.664PheTrp: 0.664 ± 0.022	1.257PheTyr: 1.257 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	5.478GlyAla: 5.478 ± 0.066	0.788GlyCys: 0.788 ± 0.019	3.663GlyAsp: 3.663 ± 0.046	4.443GlyGlu: 4.443 ± 0.049	2.912GlyPhe: 2.912 ± 0.04	5.18GlyGly: 5.18 ± 0.066	1.533GlyHis: 1.533 ± 0.034	4.74GlyIle: 4.74 ± 0.055	3.79GlyLys: 3.79 ± 0.05	7.013GlyLeu: 7.013 ± 0.072	1.462GlyMet: 1.462 ± 0.031	2.675GlyAsn: 2.675 ± 0.048	1.515GlyPro: 1.515 ± 0.028	3.014GlyGln: 3.014 ± 0.043	4.135GlyArg: 4.135 ± 0.056	4.076GlySer: 4.076 ± 0.06	3.756GlyThr: 3.756 ± 0.048	5.343GlyVal: 5.343 ± 0.054	1.083GlyTrp: 1.083 ± 0.025	2.32GlyTyr: 2.32 ± 0.031	0.001GlyXaa: 0.001 ± 0.001
His	1.687HisAla: 1.687 ± 0.042	0.253HisCys: 0.253 ± 0.012	0.889HisAsp: 0.889 ± 0.024	1.082HisGlu: 1.082 ± 0.02	0.822HisPhe: 0.822 ± 0.022	1.371HisGly: 1.371 ± 0.03	0.712HisHis: 0.712 ± 0.024	1.104HisIle: 1.104 ± 0.024	0.81HisLys: 0.81 ± 0.023	2.376HisLeu: 2.376 ± 0.036	0.274HisMet: 0.274 ± 0.01	0.716HisAsn: 0.716 ± 0.02	1.406HisPro: 1.406 ± 0.028	1.246HisGln: 1.246 ± 0.027	1.747HisArg: 1.747 ± 0.051	1.216HisSer: 1.216 ± 0.022	0.92HisThr: 0.92 ± 0.022	1.175HisVal: 1.175 ± 0.031	0.349HisTrp: 0.349 ± 0.012	0.63HisTyr: 0.63 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.541IleAla: 6.541 ± 0.067	0.688IleCys: 0.688 ± 0.019	3.291IleAsp: 3.291 ± 0.04	4.038IleGlu: 4.038 ± 0.048	2.258IlePhe: 2.258 ± 0.035	4.269IleGly: 4.269 ± 0.056	1.214IleHis: 1.214 ± 0.027	3.294IleIle: 3.294 ± 0.047	2.827IleLys: 2.827 ± 0.043	6.004IleLeu: 6.004 ± 0.065	0.765IleMet: 0.765 ± 0.021	2.584IleAsn: 2.584 ± 0.041	3.286IlePro: 3.286 ± 0.042	2.685IleGln: 2.685 ± 0.035	3.048IleArg: 3.048 ± 0.043	3.928IleSer: 3.928 ± 0.044	3.275IleThr: 3.275 ± 0.04	4.141IleVal: 4.141 ± 0.049	0.8IleTrp: 0.8 ± 0.022	1.777IleTyr: 1.777 ± 0.031	0.001IleXaa: 0.001 ± 0.001
Lys	4.035LysAla: 4.035 ± 0.049	0.318LysCys: 0.318 ± 0.013	2.126LysAsp: 2.126 ± 0.035	2.919LysGlu: 2.919 ± 0.04	1.642LysPhe: 1.642 ± 0.031	2.68LysGly: 2.68 ± 0.036	0.882LysHis: 0.882 ± 0.021	3.081LysIle: 3.081 ± 0.046	2.345LysLys: 2.345 ± 0.038	5.116LysLeu: 5.116 ± 0.059	0.913LysMet: 0.913 ± 0.023	1.975LysAsn: 1.975 ± 0.036	2.464LysPro: 2.464 ± 0.036	2.813LysGln: 2.813 ± 0.035	2.546LysArg: 2.546 ± 0.034	2.783LysSer: 2.783 ± 0.042	2.825LysThr: 2.825 ± 0.042	3.202LysVal: 3.202 ± 0.041	0.497LysTrp: 0.497 ± 0.015	1.403LysTyr: 1.403 ± 0.028	0.001LysXaa: 0.001 ± 0.001
Leu	9.81LeuAla: 9.81 ± 0.085	1.016LeuCys: 1.016 ± 0.022	5.194LeuAsp: 5.194 ± 0.057	7.184LeuGlu: 7.184 ± 0.074	3.673LeuPhe: 3.673 ± 0.046	7.565LeuGly: 7.565 ± 0.07	2.151LeuHis: 2.151 ± 0.037	5.921LeuIle: 5.921 ± 0.06	5.231LeuLys: 5.231 ± 0.056	11.261LeuLeu: 11.261 ± 0.098	1.997LeuMet: 1.997 ± 0.03	4.215LeuAsn: 4.215 ± 0.058	5.684LeuPro: 5.684 ± 0.054	5.725LeuGln: 5.725 ± 0.068	6.318LeuArg: 6.318 ± 0.069	7.072LeuSer: 7.072 ± 0.07	5.993LeuThr: 5.993 ± 0.065	7.557LeuVal: 7.557 ± 0.066	1.4LeuTrp: 1.4 ± 0.035	2.562LeuTyr: 2.562 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	1.631MetAla: 1.631 ± 0.026	0.137MetCys: 0.137 ± 0.008	0.713MetAsp: 0.713 ± 0.019	0.965MetGlu: 0.965 ± 0.021	0.537MetPhe: 0.537 ± 0.015	1.224MetGly: 1.224 ± 0.025	0.344MetHis: 0.344 ± 0.014	0.966MetIle: 0.966 ± 0.026	0.967MetLys: 0.967 ± 0.023	1.911MetLeu: 1.911 ± 0.032	0.399MetMet: 0.399 ± 0.015	0.753MetAsn: 0.753 ± 0.019	0.913MetPro: 0.913 ± 0.019	0.947MetGln: 0.947 ± 0.022	1.076MetArg: 1.076 ± 0.026	1.28MetSer: 1.28 ± 0.022	1.309MetThr: 1.309 ± 0.025	1.233MetVal: 1.233 ± 0.023	0.163MetTrp: 0.163 ± 0.01	0.366MetTyr: 0.366 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.878AsnAla: 2.878 ± 0.047	0.428AsnCys: 0.428 ± 0.015	1.507AsnAsp: 1.507 ± 0.027	1.826AsnGlu: 1.826 ± 0.034	1.671AsnPhe: 1.671 ± 0.032	2.55AsnGly: 2.55 ± 0.043	0.775AsnHis: 0.775 ± 0.019	2.469AsnIle: 2.469 ± 0.04	1.626AsnLys: 1.626 ± 0.032	4.825AsnLeu: 4.825 ± 0.056	0.56AsnMet: 0.56 ± 0.015	1.851AsnAsn: 1.851 ± 0.048	2.646AsnPro: 2.646 ± 0.035	2.378AsnGln: 2.378 ± 0.039	2.305AsnArg: 2.305 ± 0.032	2.71AsnSer: 2.71 ± 0.042	2.147AsnThr: 2.147 ± 0.037	2.259AsnVal: 2.259 ± 0.04	0.674AsnTrp: 0.674 ± 0.019	1.309AsnTyr: 1.309 ± 0.025	0.001AsnXaa: 0.001 ± 0.001
Pro	3.604ProAla: 3.604 ± 0.049	0.364ProCys: 0.364 ± 0.013	2.9ProAsp: 2.9 ± 0.036	3.794ProGlu: 3.794 ± 0.044	1.686ProPhe: 1.686 ± 0.032	3.181ProGly: 3.181 ± 0.044	1.01ProHis: 1.01 ± 0.025	2.771ProIle: 2.771 ± 0.042	2.208ProLys: 2.208 ± 0.034	4.579ProLeu: 4.579 ± 0.051	0.766ProMet: 0.766 ± 0.02	2.115ProAsn: 2.115 ± 0.036	2.487ProPro: 2.487 ± 0.056	2.616ProGln: 2.616 ± 0.042	2.256ProArg: 2.256 ± 0.04	3.049ProSer: 3.049 ± 0.046	2.794ProThr: 2.794 ± 0.044	3.53ProVal: 3.53 ± 0.047	0.58ProTrp: 0.58 ± 0.014	1.283ProTyr: 1.283 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.933GlnAla: 4.933 ± 0.065	0.339GlnCys: 0.339 ± 0.013	2.05GlnAsp: 2.05 ± 0.031	3.637GlnGlu: 3.637 ± 0.048	1.735GlnPhe: 1.735 ± 0.026	3.075GlnGly: 3.075 ± 0.043	1.175GlnHis: 1.175 ± 0.03	3.232GlnIle: 3.232 ± 0.041	2.705GlnLys: 2.705 ± 0.04	5.862GlnLeu: 5.862 ± 0.063	1.041GlnMet: 1.041 ± 0.021	1.941GlnAsn: 1.941 ± 0.031	2.77GlnPro: 2.77 ± 0.045	4.026GlnGln: 4.026 ± 0.061	3.917GlnArg: 3.917 ± 0.075	2.681GlnSer: 2.681 ± 0.038	2.781GlnThr: 2.781 ± 0.041	3.917GlnVal: 3.917 ± 0.047	0.622GlnTrp: 0.622 ± 0.018	1.225GlnTyr: 1.225 ± 0.025	0.002GlnXaa: 0.002 ± 0.001
Arg	4.96ArgAla: 4.96 ± 0.094	0.611ArgCys: 0.611 ± 0.019	2.999ArgAsp: 2.999 ± 0.046	3.821ArgGlu: 3.821 ± 0.056	2.323ArgPhe: 2.323 ± 0.038	4.025ArgGly: 4.025 ± 0.07	1.518ArgHis: 1.518 ± 0.041	3.412ArgIle: 3.412 ± 0.045	2.357ArgLys: 2.357 ± 0.037	6.687ArgLeu: 6.687 ± 0.072	1.134ArgMet: 1.134 ± 0.023	2.107ArgAsn: 2.107 ± 0.038	2.463ArgPro: 2.463 ± 0.04	3.616ArgGln: 3.616 ± 0.048	5.023ArgArg: 5.023 ± 0.106	3.309ArgSer: 3.309 ± 0.041	2.788ArgThr: 2.788 ± 0.042	4.387ArgVal: 4.387 ± 0.06	0.851ArgTrp: 0.851 ± 0.024	1.91ArgTyr: 1.91 ± 0.036	0.001ArgXaa: 0.001 ± 0.001
Ser	4.446SerAla: 4.446 ± 0.052	0.626SerCys: 0.626 ± 0.018	2.911SerAsp: 2.911 ± 0.043	3.553SerGlu: 3.553 ± 0.047	2.428SerPhe: 2.428 ± 0.036	4.513SerGly: 4.513 ± 0.062	1.247SerHis: 1.247 ± 0.029	3.422SerIle: 3.422 ± 0.044	2.711SerLys: 2.711 ± 0.039	6.839SerLeu: 6.839 ± 0.07	1.092SerMet: 1.092 ± 0.023	2.527SerAsn: 2.527 ± 0.035	3.329SerPro: 3.329 ± 0.044	3.305SerGln: 3.305 ± 0.047	3.386SerArg: 3.386 ± 0.037	4.396SerSer: 4.396 ± 0.065	3.369SerThr: 3.369 ± 0.052	4.206SerVal: 4.206 ± 0.048	0.879SerTrp: 0.879 ± 0.024	1.712SerTyr: 1.712 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	4.667ThrAla: 4.667 ± 0.055	0.457ThrCys: 0.457 ± 0.013	2.462ThrAsp: 2.462 ± 0.037	3.092ThrGlu: 3.092 ± 0.042	2.033ThrPhe: 2.033 ± 0.031	4.093ThrGly: 4.093 ± 0.058	1.013ThrHis: 1.013 ± 0.022	3.273ThrIle: 3.273 ± 0.04	2.257ThrLys: 2.257 ± 0.03	5.992ThrLeu: 5.992 ± 0.056	0.765ThrMet: 0.765 ± 0.024	2.096ThrAsn: 2.096 ± 0.035	3.445ThrPro: 3.445 ± 0.047	2.868ThrGln: 2.868 ± 0.04	2.563ThrArg: 2.563 ± 0.033	3.382ThrSer: 3.382 ± 0.046	3.217ThrThr: 3.217 ± 0.049	4.081ThrVal: 4.081 ± 0.047	0.673ThrTrp: 0.673 ± 0.021	1.532ThrTyr: 1.532 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	7.03ValAla: 7.03 ± 0.078	0.729ValCys: 0.729 ± 0.02	3.814ValAsp: 3.814 ± 0.056	5.007ValGlu: 5.007 ± 0.057	2.645ValPhe: 2.645 ± 0.038	5.389ValGly: 5.389 ± 0.061	1.317ValHis: 1.317 ± 0.027	4.164ValIle: 4.164 ± 0.052	3.255ValLys: 3.255 ± 0.04	7.261ValLeu: 7.261 ± 0.063	1.372ValMet: 1.372 ± 0.027	2.738ValAsn: 2.738 ± 0.036	3.142ValPro: 3.142 ± 0.047	3.134ValGln: 3.134 ± 0.041	4.039ValArg: 4.039 ± 0.05	4.238ValSer: 4.238 ± 0.053	3.835ValThr: 3.835 ± 0.049	5.746ValVal: 5.746 ± 0.069	0.873ValTrp: 0.873 ± 0.021	1.812ValTyr: 1.812 ± 0.03	0.002ValXaa: 0.002 ± 0.001
Trp	0.883TrpAla: 0.883 ± 0.023	0.151TrpCys: 0.151 ± 0.009	0.633TrpAsp: 0.633 ± 0.023	0.888TrpGlu: 0.888 ± 0.024	0.584TrpPhe: 0.584 ± 0.019	0.93TrpGly: 0.93 ± 0.025	0.315TrpHis: 0.315 ± 0.013	0.783TrpIle: 0.783 ± 0.019	0.601TrpLys: 0.601 ± 0.02	1.801TrpLeu: 1.801 ± 0.035	0.297TrpMet: 0.297 ± 0.012	0.61TrpAsn: 0.61 ± 0.02	0.215TrpPro: 0.215 ± 0.011	1.054TrpGln: 1.054 ± 0.027	0.919TrpArg: 0.919 ± 0.024	0.815TrpSer: 0.815 ± 0.024	0.618TrpThr: 0.618 ± 0.02	0.934TrpVal: 0.934 ± 0.022	0.263TrpTrp: 0.263 ± 0.013	0.406TrpTyr: 0.406 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.102TyrAla: 2.102 ± 0.031	0.376TyrCys: 0.376 ± 0.014	1.342TyrAsp: 1.342 ± 0.026	1.644TyrGlu: 1.644 ± 0.031	1.258TyrPhe: 1.258 ± 0.026	1.976TyrGly: 1.976 ± 0.03	0.647TyrHis: 0.647 ± 0.018	1.622TyrIle: 1.622 ± 0.027	1.282TyrLys: 1.282 ± 0.024	3.316TyrLeu: 3.316 ± 0.046	0.413TyrMet: 0.413 ± 0.015	1.135TyrAsn: 1.135 ± 0.027	1.526TyrPro: 1.526 ± 0.029	1.777TyrGln: 1.777 ± 0.034	1.845TyrArg: 1.845 ± 0.028	1.804TyrSer: 1.804 ± 0.034	1.462TyrThr: 1.462 ± 0.029	1.68TyrVal: 1.68 ± 0.031	0.513TyrTrp: 0.513 ± 0.016	1.04TyrTyr: 1.04 ± 0.027	0.0TyrXaa: 0.0 ± 0.001
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.003XaaLeu: 0.003 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.003XaaVal: 0.003 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.018XaaXaa: 0.018 ± 0.011

Statistics based on 6864 proteins (2116098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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