Amino acid dipepetide frequency for Fimbriimonas ginsengisoli Gsoil 348

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.61AlaAla: 11.61 ± 0.109	0.999AlaCys: 0.999 ± 0.027	5.498AlaAsp: 5.498 ± 0.064	6.263AlaGlu: 6.263 ± 0.087	3.883AlaPhe: 3.883 ± 0.054	8.602AlaGly: 8.602 ± 0.077	1.944AlaHis: 1.944 ± 0.037	5.567AlaIle: 5.567 ± 0.064	4.734AlaLys: 4.734 ± 0.07	10.263AlaLeu: 10.263 ± 0.099	2.738AlaMet: 2.738 ± 0.044	3.136AlaAsn: 3.136 ± 0.052	4.794AlaPro: 4.794 ± 0.068	3.478AlaGln: 3.478 ± 0.051	6.291AlaArg: 6.291 ± 0.074	6.094AlaSer: 6.094 ± 0.064	6.119AlaThr: 6.119 ± 0.09	7.403AlaVal: 7.403 ± 0.081	1.527AlaTrp: 1.527 ± 0.034	2.63AlaTyr: 2.63 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.832CysAla: 0.832 ± 0.028	0.123CysCys: 0.123 ± 0.009	0.562CysAsp: 0.562 ± 0.021	0.495CysGlu: 0.495 ± 0.018	0.319CysPhe: 0.319 ± 0.013	0.941CysGly: 0.941 ± 0.028	0.251CysHis: 0.251 ± 0.015	0.352CysIle: 0.352 ± 0.017	0.224CysLys: 0.224 ± 0.014	0.859CysLeu: 0.859 ± 0.024	0.152CysMet: 0.152 ± 0.01	0.241CysAsn: 0.241 ± 0.014	0.486CysPro: 0.486 ± 0.022	0.255CysGln: 0.255 ± 0.014	0.623CysArg: 0.623 ± 0.021	0.5CysSer: 0.5 ± 0.019	0.407CysThr: 0.407 ± 0.018	0.619CysVal: 0.619 ± 0.021	0.137CysTrp: 0.137 ± 0.009	0.249CysTyr: 0.249 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.646AspAla: 5.646 ± 0.064	0.426AspCys: 0.426 ± 0.018	2.953AspAsp: 2.953 ± 0.053	3.522AspGlu: 3.522 ± 0.053	2.122AspPhe: 2.122 ± 0.039	5.289AspGly: 5.289 ± 0.072	1.207AspHis: 1.207 ± 0.026	2.252AspIle: 2.252 ± 0.041	1.912AspLys: 1.912 ± 0.041	5.923AspLeu: 5.923 ± 0.064	1.097AspMet: 1.097 ± 0.025	1.393AspAsn: 1.393 ± 0.03	4.014AspPro: 4.014 ± 0.061	1.763AspGln: 1.763 ± 0.04	4.242AspArg: 4.242 ± 0.059	2.88AspSer: 2.88 ± 0.048	2.607AspThr: 2.607 ± 0.041	4.052AspVal: 4.052 ± 0.057	1.104AspTrp: 1.104 ± 0.027	1.518AspTyr: 1.518 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.733GluAla: 6.733 ± 0.089	0.413GluCys: 0.413 ± 0.016	2.646GluAsp: 2.646 ± 0.052	3.898GluGlu: 3.898 ± 0.07	2.233GluPhe: 2.233 ± 0.041	4.509GluGly: 4.509 ± 0.07	1.216GluHis: 1.216 ± 0.03	3.4GluIle: 3.4 ± 0.061	2.443GluLys: 2.443 ± 0.044	5.827GluLeu: 5.827 ± 0.074	1.667GluMet: 1.667 ± 0.036	1.786GluAsn: 1.786 ± 0.03	2.909GluPro: 2.909 ± 0.049	1.964GluGln: 1.964 ± 0.034	4.689GluArg: 4.689 ± 0.067	3.3GluSer: 3.3 ± 0.047	3.087GluThr: 3.087 ± 0.048	4.405GluVal: 4.405 ± 0.067	0.939GluTrp: 0.939 ± 0.026	1.403GluTyr: 1.403 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.969PheAla: 3.969 ± 0.063	0.406PheCys: 0.406 ± 0.014	2.665PheAsp: 2.665 ± 0.042	2.315PheGlu: 2.315 ± 0.04	1.497PhePhe: 1.497 ± 0.035	3.689PheGly: 3.689 ± 0.051	0.799PheHis: 0.799 ± 0.022	1.433PheIle: 1.433 ± 0.034	1.175PheLys: 1.175 ± 0.029	3.557PheLeu: 3.557 ± 0.054	0.699PheMet: 0.699 ± 0.023	1.187PheAsn: 1.187 ± 0.029	1.905PhePro: 1.905 ± 0.036	1.224PheGln: 1.224 ± 0.026	2.491PheArg: 2.491 ± 0.042	2.328PheSer: 2.328 ± 0.042	2.201PheThr: 2.201 ± 0.043	3.084PheVal: 3.084 ± 0.051	0.597PheTrp: 0.597 ± 0.022	1.08PheTyr: 1.08 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	7.87GlyAla: 7.87 ± 0.079	0.913GlyCys: 0.913 ± 0.024	4.601GlyAsp: 4.601 ± 0.058	4.716GlyGlu: 4.716 ± 0.07	3.748GlyPhe: 3.748 ± 0.057	7.842GlyGly: 7.842 ± 0.12	1.977GlyHis: 1.977 ± 0.042	4.577GlyIle: 4.577 ± 0.061	4.182GlyLys: 4.182 ± 0.061	7.734GlyLeu: 7.734 ± 0.074	2.211GlyMet: 2.211 ± 0.039	2.662GlyAsn: 2.662 ± 0.042	3.672GlyPro: 3.672 ± 0.056	2.875GlyGln: 2.875 ± 0.044	5.507GlyArg: 5.507 ± 0.069	5.298GlySer: 5.298 ± 0.065	5.208GlyThr: 5.208 ± 0.086	6.081GlyVal: 6.081 ± 0.067	1.535GlyTrp: 1.535 ± 0.038	2.646GlyTyr: 2.646 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.943HisAla: 1.943 ± 0.04	0.212HisCys: 0.212 ± 0.012	1.155HisAsp: 1.155 ± 0.028	1.201HisGlu: 1.201 ± 0.029	0.817HisPhe: 0.817 ± 0.026	1.882HisGly: 1.882 ± 0.035	0.579HisHis: 0.579 ± 0.022	0.878HisIle: 0.878 ± 0.025	0.55HisLys: 0.55 ± 0.02	2.161HisLeu: 2.161 ± 0.04	0.429HisMet: 0.429 ± 0.018	0.542HisAsn: 0.542 ± 0.018	1.504HisPro: 1.504 ± 0.036	0.639HisGln: 0.639 ± 0.02	1.599HisArg: 1.599 ± 0.035	1.068HisSer: 1.068 ± 0.029	0.961HisThr: 0.961 ± 0.028	1.502HisVal: 1.502 ± 0.035	0.396HisTrp: 0.396 ± 0.019	0.6HisTyr: 0.6 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.543IleAla: 5.543 ± 0.065	0.454IleCys: 0.454 ± 0.016	3.245IleAsp: 3.245 ± 0.046	3.291IleGlu: 3.291 ± 0.053	1.615IlePhe: 1.615 ± 0.033	4.426IleGly: 4.426 ± 0.06	1.029IleHis: 1.029 ± 0.028	1.51IleIle: 1.51 ± 0.036	1.561IleLys: 1.561 ± 0.036	4.387IleLeu: 4.387 ± 0.054	0.72IleMet: 0.72 ± 0.018	1.311IleAsn: 1.311 ± 0.033	2.856IlePro: 2.856 ± 0.041	1.617IleGln: 1.617 ± 0.035	3.359IleArg: 3.359 ± 0.041	2.928IleSer: 2.928 ± 0.045	2.446IleThr: 2.446 ± 0.05	3.982IleVal: 3.982 ± 0.057	0.655IleTrp: 0.655 ± 0.024	1.279IleTyr: 1.279 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.061LysAla: 4.061 ± 0.063	0.216LysCys: 0.216 ± 0.012	1.976LysAsp: 1.976 ± 0.042	2.37LysGlu: 2.37 ± 0.05	1.224LysPhe: 1.224 ± 0.025	3.168LysGly: 3.168 ± 0.05	0.694LysHis: 0.694 ± 0.022	1.972LysIle: 1.972 ± 0.032	1.784LysLys: 1.784 ± 0.039	3.617LysLeu: 3.617 ± 0.048	1.087LysMet: 1.087 ± 0.027	1.247LysAsn: 1.247 ± 0.032	2.572LysPro: 2.572 ± 0.047	1.275LysGln: 1.275 ± 0.031	2.532LysArg: 2.532 ± 0.041	2.344LysSer: 2.344 ± 0.039	2.299LysThr: 2.299 ± 0.041	2.971LysVal: 2.971 ± 0.043	0.588LysTrp: 0.588 ± 0.02	1.004LysTyr: 1.004 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.038LeuAla: 11.038 ± 0.109	0.896LeuCys: 0.896 ± 0.026	5.611LeuAsp: 5.611 ± 0.065	5.478LeuGlu: 5.478 ± 0.071	3.42LeuPhe: 3.42 ± 0.053	7.96LeuGly: 7.96 ± 0.082	1.918LeuHis: 1.918 ± 0.035	4.304LeuIle: 4.304 ± 0.051	3.718LeuLys: 3.718 ± 0.055	8.957LeuLeu: 8.957 ± 0.105	2.116LeuMet: 2.116 ± 0.033	2.865LeuAsn: 2.865 ± 0.041	5.445LeuPro: 5.445 ± 0.065	2.971LeuGln: 2.971 ± 0.051	7.066LeuArg: 7.066 ± 0.083	6.176LeuSer: 6.176 ± 0.074	5.626LeuThr: 5.626 ± 0.064	7.055LeuVal: 7.055 ± 0.067	1.2LeuTrp: 1.2 ± 0.028	2.369LeuTyr: 2.369 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.521MetAla: 2.521 ± 0.042	0.148MetCys: 0.148 ± 0.009	1.13MetAsp: 1.13 ± 0.029	1.247MetGlu: 1.247 ± 0.029	0.756MetPhe: 0.756 ± 0.022	1.821MetGly: 1.821 ± 0.035	0.424MetHis: 0.424 ± 0.016	1.176MetIle: 1.176 ± 0.03	1.108MetLys: 1.108 ± 0.026	2.314MetLeu: 2.314 ± 0.037	0.582MetMet: 0.582 ± 0.022	0.836MetAsn: 0.836 ± 0.022	1.428MetPro: 1.428 ± 0.032	0.71MetGln: 0.71 ± 0.019	1.755MetArg: 1.755 ± 0.036	1.566MetSer: 1.566 ± 0.034	1.464MetThr: 1.464 ± 0.032	1.606MetVal: 1.606 ± 0.03	0.294MetTrp: 0.294 ± 0.015	0.505MetTyr: 0.505 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.996AsnAla: 2.996 ± 0.054	0.264AsnCys: 0.264 ± 0.012	1.676AsnAsp: 1.676 ± 0.035	1.617AsnGlu: 1.617 ± 0.035	1.126AsnPhe: 1.126 ± 0.029	3.201AsnGly: 3.201 ± 0.056	0.662AsnHis: 0.662 ± 0.025	1.218AsnIle: 1.218 ± 0.027	0.938AsnLys: 0.938 ± 0.026	3.069AsnLeu: 3.069 ± 0.045	0.614AsnMet: 0.614 ± 0.02	0.813AsnAsn: 0.813 ± 0.028	2.306AsnPro: 2.306 ± 0.045	0.945AsnGln: 0.945 ± 0.022	2.076AsnArg: 2.076 ± 0.037	1.635AsnSer: 1.635 ± 0.035	1.466AsnThr: 1.466 ± 0.038	2.361AsnVal: 2.361 ± 0.04	0.564AsnTrp: 0.564 ± 0.023	0.889AsnTyr: 0.889 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.615ProAla: 5.615 ± 0.073	0.354ProCys: 0.354 ± 0.017	3.529ProAsp: 3.529 ± 0.052	3.863ProGlu: 3.863 ± 0.06	2.131ProPhe: 2.131 ± 0.037	4.813ProGly: 4.813 ± 0.054	1.036ProHis: 1.036 ± 0.027	2.756ProIle: 2.756 ± 0.042	2.426ProLys: 2.426 ± 0.042	4.536ProLeu: 4.536 ± 0.056	1.409ProMet: 1.409 ± 0.028	2.137ProAsn: 2.137 ± 0.039	2.805ProPro: 2.805 ± 0.062	1.619ProGln: 1.619 ± 0.037	2.863ProArg: 2.863 ± 0.043	3.487ProSer: 3.487 ± 0.053	3.348ProThr: 3.348 ± 0.051	4.17ProVal: 4.17 ± 0.052	0.792ProTrp: 0.792 ± 0.021	1.527ProTyr: 1.527 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.658GlnAla: 3.658 ± 0.058	0.226GlnCys: 0.226 ± 0.012	1.492GlnAsp: 1.492 ± 0.032	1.81GlnGlu: 1.81 ± 0.037	1.172GlnPhe: 1.172 ± 0.025	2.531GlnGly: 2.531 ± 0.038	0.573GlnHis: 0.573 ± 0.021	1.972GlnIle: 1.972 ± 0.033	1.278GlnLys: 1.278 ± 0.029	2.895GlnLeu: 2.895 ± 0.049	0.851GlnMet: 0.851 ± 0.025	1.042GlnAsn: 1.042 ± 0.028	1.719GlnPro: 1.719 ± 0.037	1.099GlnGln: 1.099 ± 0.032	2.378GlnArg: 2.378 ± 0.04	1.921GlnSer: 1.921 ± 0.035	1.934GlnThr: 1.934 ± 0.036	2.503GlnVal: 2.503 ± 0.039	0.515GlnTrp: 0.515 ± 0.019	0.839GlnTyr: 0.839 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	6.161ArgAla: 6.161 ± 0.08	0.535ArgCys: 0.535 ± 0.022	3.656ArgAsp: 3.656 ± 0.051	4.429ArgGlu: 4.429 ± 0.065	2.996ArgPhe: 2.996 ± 0.045	4.546ArgGly: 4.546 ± 0.062	1.515ArgHis: 1.515 ± 0.033	3.782ArgIle: 3.782 ± 0.051	2.531ArgLys: 2.531 ± 0.039	7.406ArgLeu: 7.406 ± 0.086	1.846ArgMet: 1.846 ± 0.035	2.076ArgAsn: 2.076 ± 0.038	3.47ArgPro: 3.47 ± 0.053	2.537ArgGln: 2.537 ± 0.046	5.216ArgArg: 5.216 ± 0.069	3.873ArgSer: 3.873 ± 0.048	3.666ArgThr: 3.666 ± 0.052	4.717ArgVal: 4.717 ± 0.065	1.115ArgTrp: 1.115 ± 0.029	2.103ArgTyr: 2.103 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.855SerAla: 5.855 ± 0.072	0.433SerCys: 0.433 ± 0.018	3.363SerAsp: 3.363 ± 0.042	3.269SerGlu: 3.269 ± 0.053	2.454SerPhe: 2.454 ± 0.044	5.771SerGly: 5.771 ± 0.076	1.244SerHis: 1.244 ± 0.031	2.936SerIle: 2.936 ± 0.044	2.174SerLys: 2.174 ± 0.041	5.758SerLeu: 5.758 ± 0.07	1.447SerMet: 1.447 ± 0.029	1.867SerAsn: 1.867 ± 0.044	3.532SerPro: 3.532 ± 0.05	1.93SerGln: 1.93 ± 0.035	3.72SerArg: 3.72 ± 0.051	3.812SerSer: 3.812 ± 0.067	3.415SerThr: 3.415 ± 0.056	4.548SerVal: 4.548 ± 0.061	0.926SerTrp: 0.926 ± 0.028	1.68SerTyr: 1.68 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.515ThrAla: 5.515 ± 0.089	0.439ThrCys: 0.439 ± 0.016	2.987ThrAsp: 2.987 ± 0.05	2.828ThrGlu: 2.828 ± 0.047	2.359ThrPhe: 2.359 ± 0.048	5.191ThrGly: 5.191 ± 0.077	1.092ThrHis: 1.092 ± 0.026	3.001ThrIle: 3.001 ± 0.056	1.998ThrLys: 1.998 ± 0.036	5.742ThrLeu: 5.742 ± 0.074	1.233ThrMet: 1.233 ± 0.032	1.655ThrAsn: 1.655 ± 0.038	3.562ThrPro: 3.562 ± 0.048	1.614ThrGln: 1.614 ± 0.033	3.034ThrArg: 3.034 ± 0.04	3.478ThrSer: 3.478 ± 0.063	3.371ThrThr: 3.371 ± 0.076	4.776ThrVal: 4.776 ± 0.091	0.949ThrTrp: 0.949 ± 0.029	1.673ThrTyr: 1.673 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	8.127ValAla: 8.127 ± 0.08	0.726ValCys: 0.726 ± 0.023	4.538ValAsp: 4.538 ± 0.058	4.503ValGlu: 4.503 ± 0.061	2.718ValPhe: 2.718 ± 0.043	5.989ValGly: 5.989 ± 0.069	1.462ValHis: 1.462 ± 0.034	3.292ValIle: 3.292 ± 0.051	2.774ValLys: 2.774 ± 0.052	7.034ValLeu: 7.034 ± 0.067	1.58ValMet: 1.58 ± 0.035	2.177ValAsn: 2.177 ± 0.043	4.112ValPro: 4.112 ± 0.058	2.307ValGln: 2.307 ± 0.033	5.382ValArg: 5.382 ± 0.072	4.667ValSer: 4.667 ± 0.064	4.554ValThr: 4.554 ± 0.083	6.272ValVal: 6.272 ± 0.066	1.023ValTrp: 1.023 ± 0.029	1.906ValTyr: 1.906 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.253TrpAla: 1.253 ± 0.03	0.171TrpCys: 0.171 ± 0.011	0.89TrpAsp: 0.89 ± 0.024	0.762TrpGlu: 0.762 ± 0.024	0.627TrpPhe: 0.627 ± 0.023	1.128TrpGly: 1.128 ± 0.029	0.396TrpHis: 0.396 ± 0.016	0.83TrpIle: 0.83 ± 0.028	0.709TrpLys: 0.709 ± 0.025	1.53TrpLeu: 1.53 ± 0.033	0.424TrpMet: 0.424 ± 0.017	0.646TrpAsn: 0.646 ± 0.02	0.686TrpPro: 0.686 ± 0.023	0.646TrpGln: 0.646 ± 0.018	1.142TrpArg: 1.142 ± 0.028	1.121TrpSer: 1.121 ± 0.032	0.95TrpThr: 0.95 ± 0.031	1.041TrpVal: 1.041 ± 0.029	0.297TrpTrp: 0.297 ± 0.015	0.416TrpTyr: 0.416 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.63TyrAla: 2.63 ± 0.045	0.275TyrCys: 0.275 ± 0.013	1.746TyrAsp: 1.746 ± 0.044	1.591TyrGlu: 1.591 ± 0.035	1.085TyrPhe: 1.085 ± 0.031	2.556TyrGly: 2.556 ± 0.047	0.603TyrHis: 0.603 ± 0.019	1.006TyrIle: 1.006 ± 0.026	0.785TyrLys: 0.785 ± 0.026	2.623TyrLeu: 2.623 ± 0.043	0.488TyrMet: 0.488 ± 0.018	0.819TyrAsn: 0.819 ± 0.028	1.439TyrPro: 1.439 ± 0.031	0.939TyrGln: 0.939 ± 0.022	2.209TyrArg: 2.209 ± 0.043	1.654TyrSer: 1.654 ± 0.034	1.365TyrThr: 1.365 ± 0.036	1.992TyrVal: 1.992 ± 0.036	0.512TyrTrp: 0.512 ± 0.02	0.855TyrTyr: 0.855 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4817 proteins (1529550 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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