Amino acid dipepetide frequency for Tomato bright yellow mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.287AlaAla: 4.287 ± 1.663
2.144AlaCys: 2.144 ± 1.536
1.072AlaAsp: 1.072 ± 0.768
3.215AlaGlu: 3.215 ± 2.462
1.072AlaPhe: 1.072 ± 0.768
2.144AlaGly: 2.144 ± 0.831
1.072AlaHis: 1.072 ± 1.336
2.144AlaIle: 2.144 ± 1.537
4.287AlaLys: 4.287 ± 1.663
4.287AlaLeu: 4.287 ± 1.089
0.0AlaMet: 0.0 ± 0.0
4.287AlaAsn: 4.287 ± 2.179
0.0AlaPro: 0.0 ± 0.0
4.287AlaGln: 4.287 ± 2.415
6.431AlaArg: 6.431 ± 4.61
6.431AlaSer: 6.431 ± 0.692
4.287AlaThr: 4.287 ± 1.64
2.144AlaVal: 2.144 ± 0.831
0.0AlaTrp: 0.0 ± 0.0
1.072AlaTyr: 1.072 ± 1.267
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.072CysAsp: 1.072 ± 0.768
2.144CysGlu: 2.144 ± 0.831
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.144CysIle: 2.144 ± 1.536
3.215CysLys: 3.215 ± 1.054
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.072CysAsn: 1.072 ± 0.768
0.0CysPro: 0.0 ± 0.0
1.072CysGln: 1.072 ± 1.267
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
5.359CysThr: 5.359 ± 4.029
1.072CysVal: 1.072 ± 0.95
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.215AspAla: 3.215 ± 1.587
0.0AspCys: 0.0 ± 0.0
5.359AspAsp: 5.359 ± 2.672
2.144AspGlu: 2.144 ± 1.537
3.215AspPhe: 3.215 ± 1.288
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
2.144AspIle: 2.144 ± 0.831
2.144AspLys: 2.144 ± 0.831
3.215AspLeu: 3.215 ± 0.971
1.072AspMet: 1.072 ± 1.267
2.144AspAsn: 2.144 ± 1.901
1.072AspPro: 1.072 ± 0.768
0.0AspGln: 0.0 ± 0.0
3.215AspArg: 3.215 ± 2.177
4.287AspSer: 4.287 ± 1.089
0.0AspThr: 0.0 ± 0.0
5.359AspVal: 5.359 ± 1.349
1.072AspTrp: 1.072 ± 0.768
3.215AspTyr: 3.215 ± 2.305
0.0AspXaa: 0.0 ± 0.0
Glu
2.144GluAla: 2.144 ± 0.831
0.0GluCys: 0.0 ± 0.0
1.072GluAsp: 1.072 ± 1.267
4.287GluGlu: 4.287 ± 2.426
2.144GluPhe: 2.144 ± 1.537
5.359GluGly: 5.359 ± 1.616
1.072GluHis: 1.072 ± 0.768
3.215GluIle: 3.215 ± 0.971
1.072GluLys: 1.072 ± 0.768
2.144GluLeu: 2.144 ± 1.537
1.072GluMet: 1.072 ± 0.768
3.215GluAsn: 3.215 ± 0.971
2.144GluPro: 2.144 ± 0.831
2.144GluGln: 2.144 ± 1.901
2.144GluArg: 2.144 ± 1.775
3.215GluSer: 3.215 ± 2.305
1.072GluThr: 1.072 ± 1.267
3.215GluVal: 3.215 ± 1.587
2.144GluTrp: 2.144 ± 0.831
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.144PheAla: 2.144 ± 1.158
1.072PheCys: 1.072 ± 0.95
2.144PheAsp: 2.144 ± 0.831
1.072PheGlu: 1.072 ± 0.95
1.072PhePhe: 1.072 ± 0.768
3.215PheGly: 3.215 ± 0.971
2.144PheHis: 2.144 ± 1.537
2.144PheIle: 2.144 ± 1.158
1.072PheLys: 1.072 ± 1.267
7.503PheLeu: 7.503 ± 4.583
1.072PheMet: 1.072 ± 0.666
4.287PheAsn: 4.287 ± 1.06
1.072PhePro: 1.072 ± 0.768
2.144PheGln: 2.144 ± 1.775
2.144PheArg: 2.144 ± 0.831
3.215PheSer: 3.215 ± 1.759
3.215PheThr: 3.215 ± 1.587
1.072PheVal: 1.072 ± 1.267
2.144PheTrp: 2.144 ± 1.901
4.287PheTyr: 4.287 ± 2.807
0.0PheXaa: 0.0 ± 0.0
Gly
2.144GlyAla: 2.144 ± 1.537
1.072GlyCys: 1.072 ± 0.95
4.287GlyAsp: 4.287 ± 3.073
3.215GlyGlu: 3.215 ± 1.408
0.0GlyPhe: 0.0 ± 0.0
4.287GlyGly: 4.287 ± 1.663
1.072GlyHis: 1.072 ± 0.768
5.359GlyIle: 5.359 ± 2.383
5.359GlyLys: 5.359 ± 2.383
1.072GlyLeu: 1.072 ± 0.768
0.0GlyMet: 0.0 ± 0.0
3.215GlyAsn: 3.215 ± 1.759
1.072GlyPro: 1.072 ± 0.95
4.287GlyGln: 4.287 ± 1.663
4.287GlyArg: 4.287 ± 3.68
3.215GlySer: 3.215 ± 2.379
4.287GlyThr: 4.287 ± 1.089
3.215GlyVal: 3.215 ± 2.358
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.215HisAla: 3.215 ± 1.759
0.0HisCys: 0.0 ± 0.0
1.072HisAsp: 1.072 ± 0.95
1.072HisGlu: 1.072 ± 0.768
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.072HisHis: 1.072 ± 0.768
3.215HisIle: 3.215 ± 1.408
1.072HisLys: 1.072 ± 1.267
2.144HisLeu: 2.144 ± 1.158
0.0HisMet: 0.0 ± 0.0
6.431HisAsn: 6.431 ± 3.57
2.144HisPro: 2.144 ± 1.537
2.144HisGln: 2.144 ± 0.831
3.215HisArg: 3.215 ± 1.612
2.144HisSer: 2.144 ± 1.158
2.144HisThr: 2.144 ± 1.901
2.144HisVal: 2.144 ± 1.901
1.072HisTrp: 1.072 ± 0.768
1.072HisTyr: 1.072 ± 0.768
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.072IleCys: 1.072 ± 1.336
1.072IleAsp: 1.072 ± 0.768
1.072IleGlu: 1.072 ± 0.768
4.287IlePhe: 4.287 ± 1.999
2.144IleGly: 2.144 ± 1.537
2.144IleHis: 2.144 ± 1.536
2.144IleIle: 2.144 ± 1.537
3.215IleLys: 3.215 ± 1.288
4.287IleLeu: 4.287 ± 1.49
2.144IleMet: 2.144 ± 1.447
2.144IleAsn: 2.144 ± 1.537
4.287IlePro: 4.287 ± 2.258
5.359IleGln: 5.359 ± 0.577
7.503IleArg: 7.503 ± 0.26
7.503IleSer: 7.503 ± 2.814
4.287IleThr: 4.287 ± 2.098
3.215IleVal: 3.215 ± 2.305
0.0IleTrp: 0.0 ± 0.0
3.215IleTyr: 3.215 ± 2.177
0.0IleXaa: 0.0 ± 0.0
Lys
3.215LysAla: 3.215 ± 0.971
0.0LysCys: 0.0 ± 0.0
3.215LysAsp: 3.215 ± 2.305
3.215LysGlu: 3.215 ± 2.305
3.215LysPhe: 3.215 ± 2.462
1.072LysGly: 1.072 ± 0.768
2.144LysHis: 2.144 ± 1.537
6.431LysIle: 6.431 ± 2.343
0.0LysLys: 0.0 ± 0.0
1.072LysLeu: 1.072 ± 0.95
2.144LysMet: 2.144 ± 1.537
4.287LysAsn: 4.287 ± 1.663
3.215LysPro: 3.215 ± 1.288
0.0LysGln: 0.0 ± 0.0
3.215LysArg: 3.215 ± 2.177
3.215LysSer: 3.215 ± 1.054
2.144LysThr: 2.144 ± 1.537
6.431LysVal: 6.431 ± 4.378
0.0LysTrp: 0.0 ± 0.0
3.215LysTyr: 3.215 ± 1.288
0.0LysXaa: 0.0 ± 0.0
Leu
1.072LeuAla: 1.072 ± 0.768
2.144LeuCys: 2.144 ± 0.831
3.215LeuAsp: 3.215 ± 1.587
1.072LeuGlu: 1.072 ± 0.768
4.287LeuPhe: 4.287 ± 2.653
3.215LeuGly: 3.215 ± 1.054
3.215LeuHis: 3.215 ± 2.358
2.144LeuIle: 2.144 ± 1.158
5.359LeuLys: 5.359 ± 1.289
6.431LeuLeu: 6.431 ± 2.343
0.0LeuMet: 0.0 ± 0.0
5.359LeuAsn: 5.359 ± 3.404
4.287LeuPro: 4.287 ± 2.315
5.359LeuGln: 5.359 ± 2.663
5.359LeuArg: 5.359 ± 1.439
6.431LeuSer: 6.431 ± 4.61
5.359LeuThr: 5.359 ± 2.856
3.215LeuVal: 3.215 ± 2.462
0.0LeuTrp: 0.0 ± 0.0
3.215LeuTyr: 3.215 ± 2.462
1.072LeuXaa: 1.072 ± 1.336
Met
2.144MetAla: 2.144 ± 1.536
0.0MetCys: 0.0 ± 0.0
3.215MetAsp: 3.215 ± 1.99
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.144MetGly: 2.144 ± 1.537
1.072MetHis: 1.072 ± 0.95
0.0MetIle: 0.0 ± 0.0
2.144MetLys: 2.144 ± 1.213
2.144MetLeu: 2.144 ± 1.158
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.144MetPro: 2.144 ± 0.831
1.072MetGln: 1.072 ± 0.768
0.0MetArg: 0.0 ± 0.0
1.072MetSer: 1.072 ± 0.95
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.072MetTrp: 1.072 ± 0.768
3.215MetTyr: 3.215 ± 1.99
0.0MetXaa: 0.0 ± 0.0
Asn
7.503AsnAla: 7.503 ± 2.816
2.144AsnCys: 2.144 ± 1.213
1.072AsnAsp: 1.072 ± 0.95
4.287AsnGlu: 4.287 ± 1.663
3.215AsnPhe: 3.215 ± 2.358
2.144AsnGly: 2.144 ± 1.371
5.359AsnHis: 5.359 ± 2.303
7.503AsnIle: 7.503 ± 4.164
2.144AsnLys: 2.144 ± 1.158
4.287AsnLeu: 4.287 ± 2.462
3.215AsnMet: 3.215 ± 2.626
0.0AsnAsn: 0.0 ± 0.0
3.215AsnPro: 3.215 ± 0.971
1.072AsnGln: 1.072 ± 1.267
1.072AsnArg: 1.072 ± 0.95
4.287AsnSer: 4.287 ± 1.06
2.144AsnThr: 2.144 ± 1.213
3.215AsnVal: 3.215 ± 1.587
1.072AsnTrp: 1.072 ± 0.768
2.144AsnTyr: 2.144 ± 1.537
0.0AsnXaa: 0.0 ± 0.0
Pro
1.072ProAla: 1.072 ± 1.336
1.072ProCys: 1.072 ± 0.95
3.215ProAsp: 3.215 ± 1.288
1.072ProGlu: 1.072 ± 0.768
2.144ProPhe: 2.144 ± 0.831
2.144ProGly: 2.144 ± 1.158
1.072ProHis: 1.072 ± 0.768
0.0ProIle: 0.0 ± 0.0
3.215ProLys: 3.215 ± 1.612
5.359ProLeu: 5.359 ± 2.263
2.144ProMet: 2.144 ± 1.901
2.144ProAsn: 2.144 ± 1.537
4.287ProPro: 4.287 ± 1.952
1.072ProGln: 1.072 ± 0.768
6.431ProArg: 6.431 ± 2.494
2.144ProSer: 2.144 ± 0.831
3.215ProThr: 3.215 ± 2.379
4.287ProVal: 4.287 ± 1.952
1.072ProTrp: 1.072 ± 0.768
2.144ProTyr: 2.144 ± 1.536
0.0ProXaa: 0.0 ± 0.0
Gln
4.287GlnAla: 4.287 ± 1.089
1.072GlnCys: 1.072 ± 0.768
1.072GlnAsp: 1.072 ± 0.768
4.287GlnGlu: 4.287 ± 2.098
2.144GlnPhe: 2.144 ± 2.671
1.072GlnGly: 1.072 ± 1.336
2.144GlnHis: 2.144 ± 1.158
2.144GlnIle: 2.144 ± 1.213
1.072GlnLys: 1.072 ± 0.768
2.144GlnLeu: 2.144 ± 1.537
2.144GlnMet: 2.144 ± 1.537
2.144GlnAsn: 2.144 ± 2.534
1.072GlnPro: 1.072 ± 0.768
0.0GlnGln: 0.0 ± 0.0
3.215GlnArg: 3.215 ± 1.054
4.287GlnSer: 4.287 ± 1.089
1.072GlnThr: 1.072 ± 1.267
3.215GlnVal: 3.215 ± 1.99
0.0GlnTrp: 0.0 ± 0.0
2.144GlnTyr: 2.144 ± 0.831
0.0GlnXaa: 0.0 ± 0.0
Arg
3.215ArgAla: 3.215 ± 1.587
2.144ArgCys: 2.144 ± 2.671
5.359ArgAsp: 5.359 ± 1.439
2.144ArgGlu: 2.144 ± 1.537
6.431ArgPhe: 6.431 ± 2.197
5.359ArgGly: 5.359 ± 2.465
2.144ArgHis: 2.144 ± 1.536
5.359ArgIle: 5.359 ± 2.303
2.144ArgLys: 2.144 ± 0.831
5.359ArgLeu: 5.359 ± 2.499
1.072ArgMet: 1.072 ± 1.336
1.072ArgAsn: 1.072 ± 0.768
5.359ArgPro: 5.359 ± 2.383
2.144ArgGln: 2.144 ± 1.213
10.718ArgArg: 10.718 ± 2.646
6.431ArgSer: 6.431 ± 2.108
7.503ArgThr: 7.503 ± 3.533
2.144ArgVal: 2.144 ± 0.831
1.072ArgTrp: 1.072 ± 1.336
2.144ArgTyr: 2.144 ± 1.536
0.0ArgXaa: 0.0 ± 0.0
Ser
4.287SerAla: 4.287 ± 1.952
1.072SerCys: 1.072 ± 1.336
1.072SerAsp: 1.072 ± 0.95
1.072SerGlu: 1.072 ± 0.768
3.215SerPhe: 3.215 ± 1.054
7.503SerGly: 7.503 ± 2.557
2.144SerHis: 2.144 ± 0.831
5.359SerIle: 5.359 ± 0.577
3.215SerLys: 3.215 ± 1.054
6.431SerLeu: 6.431 ± 2.364
0.0SerMet: 0.0 ± 0.0
6.431SerAsn: 6.431 ± 2.494
6.431SerPro: 6.431 ± 0.692
1.072SerGln: 1.072 ± 0.768
6.431SerArg: 6.431 ± 3.491
4.287SerSer: 4.287 ± 1.952
7.503SerThr: 7.503 ± 4.804
3.215SerVal: 3.215 ± 2.177
3.215SerTrp: 3.215 ± 1.441
3.215SerTyr: 3.215 ± 1.441
0.0SerXaa: 0.0 ± 0.0
Thr
5.359ThrAla: 5.359 ± 3.779
1.072ThrCys: 1.072 ± 1.267
1.072ThrAsp: 1.072 ± 1.336
2.144ThrGlu: 2.144 ± 0.831
3.215ThrPhe: 3.215 ± 1.408
4.287ThrGly: 4.287 ± 1.089
3.215ThrHis: 3.215 ± 1.612
0.0ThrIle: 0.0 ± 0.0
2.144ThrLys: 2.144 ± 1.537
3.215ThrLeu: 3.215 ± 1.612
1.072ThrMet: 1.072 ± 0.768
5.359ThrAsn: 5.359 ± 1.981
3.215ThrPro: 3.215 ± 1.054
0.0ThrGln: 0.0 ± 0.0
6.431ThrArg: 6.431 ± 3.491
7.503ThrSer: 7.503 ± 4.672
9.646ThrThr: 9.646 ± 7.026
3.215ThrVal: 3.215 ± 0.971
3.215ThrTrp: 3.215 ± 2.875
4.287ThrTyr: 4.287 ± 1.412
0.0ThrXaa: 0.0 ± 0.0
Val
1.072ValAla: 1.072 ± 0.768
0.0ValCys: 0.0 ± 0.0
1.072ValAsp: 1.072 ± 0.768
2.144ValGlu: 2.144 ± 1.213
2.144ValPhe: 2.144 ± 1.371
2.144ValGly: 2.144 ± 1.901
0.0ValHis: 0.0 ± 0.0
3.215ValIle: 3.215 ± 1.408
5.359ValLys: 5.359 ± 1.349
4.287ValLeu: 4.287 ± 1.663
1.072ValMet: 1.072 ± 0.95
4.287ValAsn: 4.287 ± 1.06
2.144ValPro: 2.144 ± 1.537
5.359ValGln: 5.359 ± 0.577
3.215ValArg: 3.215 ± 1.99
3.215ValSer: 3.215 ± 1.288
2.144ValThr: 2.144 ± 1.901
3.215ValVal: 3.215 ± 1.612
2.144ValTrp: 2.144 ± 1.371
8.574ValTyr: 8.574 ± 2.98
0.0ValXaa: 0.0 ± 0.0
Trp
2.144TrpAla: 2.144 ± 1.537
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.144TrpGlu: 2.144 ± 1.213
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.072TrpHis: 1.072 ± 0.768
2.144TrpIle: 2.144 ± 2.671
2.144TrpLys: 2.144 ± 0.831
1.072TrpLeu: 1.072 ± 0.95
1.072TrpMet: 1.072 ± 0.95
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.072TrpGln: 1.072 ± 0.768
1.072TrpArg: 1.072 ± 1.336
1.072TrpSer: 1.072 ± 1.336
3.215TrpThr: 3.215 ± 1.587
1.072TrpVal: 1.072 ± 0.95
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.144TyrAla: 2.144 ± 1.901
1.072TyrCys: 1.072 ± 0.768
2.144TyrAsp: 2.144 ± 1.901
1.072TyrGlu: 1.072 ± 0.95
6.431TyrPhe: 6.431 ± 3.283
3.215TyrGly: 3.215 ± 1.054
3.215TyrHis: 3.215 ± 1.587
4.287TyrIle: 4.287 ± 1.022
1.072TyrLys: 1.072 ± 0.768
4.287TyrLeu: 4.287 ± 2.426
1.072TyrMet: 1.072 ± 0.95
4.287TyrAsn: 4.287 ± 1.663
2.144TyrPro: 2.144 ± 0.831
1.072TyrGln: 1.072 ± 1.267
3.215TyrArg: 3.215 ± 1.612
3.215TyrSer: 3.215 ± 2.379
1.072TyrThr: 1.072 ± 1.267
2.144TyrVal: 2.144 ± 2.671
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
1.072XaaLeu: 1.072 ± 1.336
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (934 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski