Amino acid dipepetide frequency for Paraburkholderia sp. BL10I2N1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.349AlaAla: 16.349 ± 0.113	1.332AlaCys: 1.332 ± 0.027	6.339AlaAsp: 6.339 ± 0.057	5.806AlaGlu: 5.806 ± 0.052	4.363AlaPhe: 4.363 ± 0.044	10.171AlaGly: 10.171 ± 0.07	2.794AlaHis: 2.794 ± 0.036	5.848AlaIle: 5.848 ± 0.057	3.632AlaLys: 3.632 ± 0.045	13.521AlaLeu: 13.521 ± 0.086	3.244AlaMet: 3.244 ± 0.041	3.182AlaAsn: 3.182 ± 0.039	5.613AlaPro: 5.613 ± 0.065	5.049AlaGln: 5.049 ± 0.052	8.833AlaArg: 8.833 ± 0.075	7.371AlaSer: 7.371 ± 0.062	6.524AlaThr: 6.524 ± 0.068	8.691AlaVal: 8.691 ± 0.065	1.669AlaTrp: 1.669 ± 0.028	2.638AlaTyr: 2.638 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	1.245CysAla: 1.245 ± 0.023	0.135CysCys: 0.135 ± 0.007	0.616CysAsp: 0.616 ± 0.017	0.534CysGlu: 0.534 ± 0.015	0.343CysPhe: 0.343 ± 0.013	1.065CysGly: 1.065 ± 0.021	0.282CysHis: 0.282 ± 0.011	0.442CysIle: 0.442 ± 0.016	0.25CysLys: 0.25 ± 0.012	0.851CysLeu: 0.851 ± 0.022	0.233CysMet: 0.233 ± 0.01	0.279CysAsn: 0.279 ± 0.013	0.494CysPro: 0.494 ± 0.017	0.258CysGln: 0.258 ± 0.01	0.687CysArg: 0.687 ± 0.019	0.576CysSer: 0.576 ± 0.016	0.536CysThr: 0.536 ± 0.016	0.839CysVal: 0.839 ± 0.02	0.134CysTrp: 0.134 ± 0.008	0.233CysTyr: 0.233 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.202AspAla: 7.202 ± 0.063	0.5AspCys: 0.5 ± 0.014	3.121AspAsp: 3.121 ± 0.043	3.455AspGlu: 3.455 ± 0.041	1.966AspPhe: 1.966 ± 0.029	4.54AspGly: 4.54 ± 0.049	1.214AspHis: 1.214 ± 0.025	2.59AspIle: 2.59 ± 0.03	1.457AspLys: 1.457 ± 0.026	5.203AspLeu: 5.203 ± 0.045	1.189AspMet: 1.189 ± 0.022	1.295AspAsn: 1.295 ± 0.022	2.987AspPro: 2.987 ± 0.037	1.592AspGln: 1.592 ± 0.026	3.562AspArg: 3.562 ± 0.041	2.569AspSer: 2.569 ± 0.036	2.838AspThr: 2.838 ± 0.037	4.364AspVal: 4.364 ± 0.043	0.9AspTrp: 0.9 ± 0.02	1.478AspTyr: 1.478 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	6.537GluAla: 6.537 ± 0.056	0.438GluCys: 0.438 ± 0.012	2.2GluAsp: 2.2 ± 0.034	2.469GluGlu: 2.469 ± 0.041	1.765GluPhe: 1.765 ± 0.029	3.48GluGly: 3.48 ± 0.038	1.448GluHis: 1.448 ± 0.026	2.794GluIle: 2.794 ± 0.036	1.799GluLys: 1.799 ± 0.029	5.482GluLeu: 5.482 ± 0.054	1.215GluMet: 1.215 ± 0.024	1.392GluAsn: 1.392 ± 0.027	2.522GluPro: 2.522 ± 0.035	2.415GluGln: 2.415 ± 0.035	4.827GluArg: 4.827 ± 0.05	2.649GluSer: 2.649 ± 0.035	2.903GluThr: 2.903 ± 0.04	3.642GluVal: 3.642 ± 0.043	0.715GluTrp: 0.715 ± 0.017	1.164GluTyr: 1.164 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	4.696PheAla: 4.696 ± 0.041	0.463PheCys: 0.463 ± 0.013	2.703PheAsp: 2.703 ± 0.031	2.071PheGlu: 2.071 ± 0.033	1.482PhePhe: 1.482 ± 0.027	3.645PheGly: 3.645 ± 0.048	0.775PheHis: 0.775 ± 0.018	1.637PheIle: 1.637 ± 0.027	0.99PheLys: 0.99 ± 0.019	3.04PheLeu: 3.04 ± 0.039	0.814PheMet: 0.814 ± 0.019	1.207PheAsn: 1.207 ± 0.024	1.578PhePro: 1.578 ± 0.026	0.993PheGln: 0.993 ± 0.022	2.17PheArg: 2.17 ± 0.03	2.341PheSer: 2.341 ± 0.04	1.942PheThr: 1.942 ± 0.029	3.12PheVal: 3.12 ± 0.038	0.52PheTrp: 0.52 ± 0.016	0.974PheTyr: 0.974 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.047GlyAla: 9.047 ± 0.085	0.921GlyCys: 0.921 ± 0.021	3.946GlyAsp: 3.946 ± 0.04	4.181GlyGlu: 4.181 ± 0.044	3.375GlyPhe: 3.375 ± 0.043	6.662GlyGly: 6.662 ± 0.066	1.949GlyHis: 1.949 ± 0.032	4.288GlyIle: 4.288 ± 0.041	3.191GlyLys: 3.191 ± 0.042	7.947GlyLeu: 7.947 ± 0.058	2.241GlyMet: 2.241 ± 0.031	2.37GlyAsn: 2.37 ± 0.039	3.049GlyPro: 3.049 ± 0.037	2.821GlyGln: 2.821 ± 0.037	5.323GlyArg: 5.323 ± 0.047	4.718GlySer: 4.718 ± 0.058	4.615GlyThr: 4.615 ± 0.054	6.68GlyVal: 6.68 ± 0.059	1.361GlyTrp: 1.361 ± 0.023	2.408GlyTyr: 2.408 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	3.011HisAla: 3.011 ± 0.04	0.278HisCys: 0.278 ± 0.011	1.36HisAsp: 1.36 ± 0.024	1.257HisGlu: 1.257 ± 0.024	0.968HisPhe: 0.968 ± 0.021	2.231HisGly: 2.231 ± 0.034	0.669HisHis: 0.669 ± 0.021	0.97HisIle: 0.97 ± 0.02	0.546HisLys: 0.546 ± 0.016	2.227HisLeu: 2.227 ± 0.032	0.554HisMet: 0.554 ± 0.014	0.568HisAsn: 0.568 ± 0.016	1.49HisPro: 1.49 ± 0.026	0.709HisGln: 0.709 ± 0.019	1.705HisArg: 1.705 ± 0.028	1.157HisSer: 1.157 ± 0.022	1.134HisThr: 1.134 ± 0.022	1.802HisVal: 1.802 ± 0.026	0.415HisTrp: 0.415 ± 0.012	0.677HisTyr: 0.677 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	6.861IleAla: 6.861 ± 0.058	0.483IleCys: 0.483 ± 0.015	3.459IleAsp: 3.459 ± 0.037	3.304IleGlu: 3.304 ± 0.041	1.482IlePhe: 1.482 ± 0.03	4.596IleGly: 4.596 ± 0.047	0.974IleHis: 0.974 ± 0.021	1.665IleIle: 1.665 ± 0.028	1.366IleLys: 1.366 ± 0.025	3.515IleLeu: 3.515 ± 0.04	0.772IleMet: 0.772 ± 0.019	1.466IleAsn: 1.466 ± 0.025	2.265IlePro: 2.265 ± 0.031	1.277IleGln: 1.277 ± 0.024	2.957IleArg: 2.957 ± 0.039	2.648IleSer: 2.648 ± 0.032	2.402IleThr: 2.402 ± 0.033	4.404IleVal: 4.404 ± 0.045	0.543IleTrp: 0.543 ± 0.018	1.109IleTyr: 1.109 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.601LysAla: 3.601 ± 0.044	0.197LysCys: 0.197 ± 0.01	1.478LysAsp: 1.478 ± 0.025	1.473LysGlu: 1.473 ± 0.027	0.87LysPhe: 0.87 ± 0.019	2.254LysGly: 2.254 ± 0.032	0.7LysHis: 0.7 ± 0.016	1.536LysIle: 1.536 ± 0.028	1.286LysLys: 1.286 ± 0.03	3.281LysLeu: 3.281 ± 0.041	0.789LysMet: 0.789 ± 0.018	0.879LysAsn: 0.879 ± 0.02	1.957LysPro: 1.957 ± 0.034	1.266LysGln: 1.266 ± 0.025	2.386LysArg: 2.386 ± 0.032	1.77LysSer: 1.77 ± 0.026	1.894LysThr: 1.894 ± 0.029	2.406LysVal: 2.406 ± 0.033	0.425LysTrp: 0.425 ± 0.012	0.723LysTyr: 0.723 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.38LeuAla: 13.38 ± 0.09	1.097LeuCys: 1.097 ± 0.022	5.798LeuAsp: 5.798 ± 0.05	5.081LeuGlu: 5.081 ± 0.049	3.638LeuPhe: 3.638 ± 0.047	7.923LeuGly: 7.923 ± 0.064	2.306LeuHis: 2.306 ± 0.035	4.693LeuIle: 4.693 ± 0.052	3.451LeuLys: 3.451 ± 0.04	9.889LeuLeu: 9.889 ± 0.084	2.288LeuMet: 2.288 ± 0.03	2.846LeuAsn: 2.846 ± 0.039	5.636LeuPro: 5.636 ± 0.051	3.37LeuGln: 3.37 ± 0.039	7.121LeuArg: 7.121 ± 0.065	6.33LeuSer: 6.33 ± 0.053	5.744LeuThr: 5.744 ± 0.057	7.362LeuVal: 7.362 ± 0.07	1.135LeuTrp: 1.135 ± 0.022	2.223LeuTyr: 2.223 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.467MetAla: 2.467 ± 0.034	0.195MetCys: 0.195 ± 0.008	0.999MetAsp: 0.999 ± 0.018	0.956MetGlu: 0.956 ± 0.021	0.782MetPhe: 0.782 ± 0.017	1.589MetGly: 1.589 ± 0.026	0.607MetHis: 0.607 ± 0.016	1.158MetIle: 1.158 ± 0.027	1.091MetLys: 1.091 ± 0.022	2.691MetLeu: 2.691 ± 0.038	0.602MetMet: 0.602 ± 0.016	0.939MetAsn: 0.939 ± 0.019	1.456MetPro: 1.456 ± 0.027	0.985MetGln: 0.985 ± 0.019	1.826MetArg: 1.826 ± 0.025	1.797MetSer: 1.797 ± 0.03	1.697MetThr: 1.697 ± 0.032	1.525MetVal: 1.525 ± 0.027	0.224MetTrp: 0.224 ± 0.01	0.425MetTyr: 0.425 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.504AsnAla: 3.504 ± 0.045	0.292AsnCys: 0.292 ± 0.011	1.447AsnAsp: 1.447 ± 0.025	1.4AsnGlu: 1.4 ± 0.026	1.024AsnPhe: 1.024 ± 0.022	2.597AsnGly: 2.597 ± 0.036	0.587AsnHis: 0.587 ± 0.017	1.25AsnIle: 1.25 ± 0.024	0.708AsnLys: 0.708 ± 0.02	2.756AsnLeu: 2.756 ± 0.031	0.581AsnMet: 0.581 ± 0.016	0.849AsnAsn: 0.849 ± 0.022	1.933AsnPro: 1.933 ± 0.032	0.967AsnGln: 0.967 ± 0.023	1.919AsnArg: 1.919 ± 0.032	1.397AsnSer: 1.397 ± 0.027	1.524AsnThr: 1.524 ± 0.031	2.304AsnVal: 2.304 ± 0.034	0.449AsnTrp: 0.449 ± 0.015	0.757AsnTyr: 0.757 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.414ProAla: 6.414 ± 0.065	0.4ProCys: 0.4 ± 0.014	3.387ProAsp: 3.387 ± 0.04	3.104ProGlu: 3.104 ± 0.039	1.924ProPhe: 1.924 ± 0.029	4.244ProGly: 4.244 ± 0.043	1.318ProHis: 1.318 ± 0.026	1.975ProIle: 1.975 ± 0.033	1.505ProLys: 1.505 ± 0.028	5.08ProLeu: 5.08 ± 0.054	1.124ProMet: 1.124 ± 0.024	1.438ProAsn: 1.438 ± 0.024	2.523ProPro: 2.523 ± 0.036	1.899ProGln: 1.899 ± 0.03	2.917ProArg: 2.917 ± 0.037	2.903ProSer: 2.903 ± 0.033	2.623ProThr: 2.623 ± 0.033	4.535ProVal: 4.535 ± 0.042	0.676ProTrp: 0.676 ± 0.017	1.243ProTyr: 1.243 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.327GlnAla: 4.327 ± 0.051	0.31GlnCys: 0.31 ± 0.012	1.386GlnAsp: 1.386 ± 0.026	1.436GlnGlu: 1.436 ± 0.021	1.31GlnPhe: 1.31 ± 0.025	2.426GlnGly: 2.426 ± 0.029	0.954GlnHis: 0.954 ± 0.02	1.997GlnIle: 1.997 ± 0.03	1.143GlnLys: 1.143 ± 0.023	3.814GlnLeu: 3.814 ± 0.047	1.039GlnMet: 1.039 ± 0.023	0.97GlnAsn: 0.97 ± 0.019	2.045GlnPro: 2.045 ± 0.033	1.867GlnGln: 1.867 ± 0.036	2.938GlnArg: 2.938 ± 0.038	2.025GlnSer: 2.025 ± 0.029	2.072GlnThr: 2.072 ± 0.03	2.513GlnVal: 2.513 ± 0.031	0.558GlnTrp: 0.558 ± 0.016	0.929GlnTyr: 0.929 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	7.945ArgAla: 7.945 ± 0.079	0.661ArgCys: 0.661 ± 0.019	3.89ArgAsp: 3.89 ± 0.045	4.273ArgGlu: 4.273 ± 0.046	3.045ArgPhe: 3.045 ± 0.039	4.607ArgGly: 4.607 ± 0.047	1.986ArgHis: 1.986 ± 0.028	3.694ArgIle: 3.694 ± 0.036	2.224ArgLys: 2.224 ± 0.034	7.391ArgLeu: 7.391 ± 0.065	1.865ArgMet: 1.865 ± 0.028	2.009ArgAsn: 2.009 ± 0.033	3.156ArgPro: 3.156 ± 0.041	2.665ArgGln: 2.665 ± 0.038	5.556ArgArg: 5.556 ± 0.048	3.802ArgSer: 3.802 ± 0.039	3.595ArgThr: 3.595 ± 0.041	5.327ArgVal: 5.327 ± 0.044	1.06ArgTrp: 1.06 ± 0.022	2.031ArgTyr: 2.031 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.79SerAla: 6.79 ± 0.054	0.51SerCys: 0.51 ± 0.016	2.881SerAsp: 2.881 ± 0.032	2.612SerGlu: 2.612 ± 0.032	2.272SerPhe: 2.272 ± 0.03	5.417SerGly: 5.417 ± 0.058	1.303SerHis: 1.303 ± 0.023	2.848SerIle: 2.848 ± 0.034	1.692SerLys: 1.692 ± 0.029	5.892SerLeu: 5.892 ± 0.057	1.511SerMet: 1.511 ± 0.026	1.685SerAsn: 1.685 ± 0.026	3.007SerPro: 3.007 ± 0.038	1.879SerGln: 1.879 ± 0.026	3.939SerArg: 3.939 ± 0.042	3.536SerSer: 3.536 ± 0.047	3.287SerThr: 3.287 ± 0.041	4.488SerVal: 4.488 ± 0.043	0.733SerTrp: 0.733 ± 0.017	1.362SerTyr: 1.362 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	6.004ThrAla: 6.004 ± 0.051	0.51ThrCys: 0.51 ± 0.017	2.715ThrAsp: 2.715 ± 0.031	2.46ThrGlu: 2.46 ± 0.037	2.021ThrPhe: 2.021 ± 0.03	4.987ThrGly: 4.987 ± 0.056	1.305ThrHis: 1.305 ± 0.025	2.703ThrIle: 2.703 ± 0.039	1.31ThrLys: 1.31 ± 0.026	6.381ThrLeu: 6.381 ± 0.051	1.249ThrMet: 1.249 ± 0.022	1.449ThrAsn: 1.449 ± 0.032	3.542ThrPro: 3.542 ± 0.035	1.976ThrGln: 1.976 ± 0.031	3.687ThrArg: 3.687 ± 0.042	3.145ThrSer: 3.145 ± 0.04	3.073ThrThr: 3.073 ± 0.04	4.52ThrVal: 4.52 ± 0.047	0.743ThrTrp: 0.743 ± 0.02	1.303ThrTyr: 1.303 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	9.626ValAla: 9.626 ± 0.061	0.867ValCys: 0.867 ± 0.021	4.288ValAsp: 4.288 ± 0.048	4.241ValGlu: 4.241 ± 0.046	2.933ValPhe: 2.933 ± 0.042	5.611ValGly: 5.611 ± 0.057	1.605ValHis: 1.605 ± 0.028	3.854ValIle: 3.854 ± 0.05	2.44ValLys: 2.44 ± 0.035	7.86ValLeu: 7.86 ± 0.069	1.846ValMet: 1.846 ± 0.028	2.312ValAsn: 2.312 ± 0.037	4.026ValPro: 4.026 ± 0.043	2.514ValGln: 2.514 ± 0.032	5.234ValArg: 5.234 ± 0.052	4.776ValSer: 4.776 ± 0.047	4.64ValThr: 4.64 ± 0.047	6.422ValVal: 6.422 ± 0.062	0.973ValTrp: 0.973 ± 0.021	1.701ValTyr: 1.701 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.172TrpAla: 1.172 ± 0.026	0.163TrpCys: 0.163 ± 0.008	0.634TrpAsp: 0.634 ± 0.018	0.522TrpGlu: 0.522 ± 0.016	0.556TrpPhe: 0.556 ± 0.016	0.883TrpGly: 0.883 ± 0.017	0.408TrpHis: 0.408 ± 0.013	0.719TrpIle: 0.719 ± 0.017	0.464TrpLys: 0.464 ± 0.014	1.924TrpLeu: 1.924 ± 0.037	0.395TrpMet: 0.395 ± 0.013	0.464TrpAsn: 0.464 ± 0.014	0.656TrpPro: 0.656 ± 0.018	0.67TrpGln: 0.67 ± 0.017	1.183TrpArg: 1.183 ± 0.022	0.81TrpSer: 0.81 ± 0.02	0.759TrpThr: 0.759 ± 0.019	0.929TrpVal: 0.929 ± 0.022	0.234TrpTrp: 0.234 ± 0.011	0.338TrpTyr: 0.338 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.791TyrAla: 2.791 ± 0.033	0.282TyrCys: 0.282 ± 0.01	1.374TyrAsp: 1.374 ± 0.024	1.221TyrGlu: 1.221 ± 0.024	1.042TyrPhe: 1.042 ± 0.022	2.165TyrGly: 2.165 ± 0.03	0.546TyrHis: 0.546 ± 0.016	0.888TyrIle: 0.888 ± 0.02	0.625TyrLys: 0.625 ± 0.016	2.566TyrLeu: 2.566 ± 0.029	0.46TyrMet: 0.46 ± 0.016	0.648TyrAsn: 0.648 ± 0.017	1.297TyrPro: 1.297 ± 0.026	0.886TyrGln: 0.886 ± 0.018	2.008TyrArg: 2.008 ± 0.03	1.326TyrSer: 1.326 ± 0.026	1.283TyrThr: 1.283 ± 0.027	1.895TyrVal: 1.895 ± 0.028	0.413TyrTrp: 0.413 ± 0.013	0.682TyrTyr: 0.682 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7997 proteins (2448043 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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