Amino acid dipepetide frequency for Labrenzia alba

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.946AlaAla: 12.946 ± 0.117	1.031AlaCys: 1.031 ± 0.024	6.324AlaAsp: 6.324 ± 0.076	6.965AlaGlu: 6.965 ± 0.056	4.456AlaPhe: 4.456 ± 0.051	9.409AlaGly: 9.409 ± 0.084	1.926AlaHis: 1.926 ± 0.034	6.125AlaIle: 6.125 ± 0.065	3.769AlaLys: 3.769 ± 0.049	11.364AlaLeu: 11.364 ± 0.092	3.092AlaMet: 3.092 ± 0.041	3.108AlaAsn: 3.108 ± 0.039	4.274AlaPro: 4.274 ± 0.056	3.297AlaGln: 3.297 ± 0.041	6.605AlaArg: 6.605 ± 0.069	6.232AlaSer: 6.232 ± 0.058	5.192AlaThr: 5.192 ± 0.062	7.811AlaVal: 7.811 ± 0.072	1.255AlaTrp: 1.255 ± 0.025	2.371AlaTyr: 2.371 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.966CysAla: 0.966 ± 0.024	0.14CysCys: 0.14 ± 0.009	0.587CysAsp: 0.587 ± 0.018	0.501CysGlu: 0.501 ± 0.018	0.402CysPhe: 0.402 ± 0.014	0.972CysGly: 0.972 ± 0.026	0.283CysHis: 0.283 ± 0.013	0.463CysIle: 0.463 ± 0.015	0.283CysLys: 0.283 ± 0.012	0.968CysLeu: 0.968 ± 0.025	0.188CysMet: 0.188 ± 0.011	0.268CysAsn: 0.268 ± 0.012	0.46CysPro: 0.46 ± 0.015	0.282CysGln: 0.282 ± 0.011	0.617CysArg: 0.617 ± 0.02	0.588CysSer: 0.588 ± 0.016	0.432CysThr: 0.432 ± 0.016	0.697CysVal: 0.697 ± 0.018	0.129CysTrp: 0.129 ± 0.008	0.229CysTyr: 0.229 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.142AspAla: 6.142 ± 0.063	0.563AspCys: 0.563 ± 0.02	3.375AspAsp: 3.375 ± 0.053	3.722AspGlu: 3.722 ± 0.048	2.464AspPhe: 2.464 ± 0.041	5.293AspGly: 5.293 ± 0.079	1.292AspHis: 1.292 ± 0.028	3.43AspIle: 3.43 ± 0.046	2.051AspLys: 2.051 ± 0.031	6.679AspLeu: 6.679 ± 0.063	1.492AspMet: 1.492 ± 0.031	1.658AspAsn: 1.658 ± 0.032	3.483AspPro: 3.483 ± 0.045	1.963AspGln: 1.963 ± 0.031	4.036AspArg: 4.036 ± 0.046	2.264AspSer: 2.264 ± 0.033	3.048AspThr: 3.048 ± 0.047	4.322AspVal: 4.322 ± 0.054	1.071AspTrp: 1.071 ± 0.024	1.588AspTyr: 1.588 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.034GluAla: 7.034 ± 0.071	0.438GluCys: 0.438 ± 0.014	3.641GluAsp: 3.641 ± 0.042	3.903GluGlu: 3.903 ± 0.057	2.245GluPhe: 2.245 ± 0.032	4.309GluGly: 4.309 ± 0.052	1.249GluHis: 1.249 ± 0.027	4.05GluIle: 4.05 ± 0.052	2.871GluLys: 2.871 ± 0.043	5.845GluLeu: 5.845 ± 0.056	1.614GluMet: 1.614 ± 0.031	2.381GluAsn: 2.381 ± 0.032	2.675GluPro: 2.675 ± 0.042	2.232GluGln: 2.232 ± 0.034	4.298GluArg: 4.298 ± 0.053	2.553GluSer: 2.553 ± 0.039	4.419GluThr: 4.419 ± 0.05	3.952GluVal: 3.952 ± 0.049	0.677GluTrp: 0.677 ± 0.018	1.097GluTyr: 1.097 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.463PheAla: 4.463 ± 0.052	0.495PheCys: 0.495 ± 0.016	2.856PheAsp: 2.856 ± 0.037	2.64PheGlu: 2.64 ± 0.038	1.751PhePhe: 1.751 ± 0.032	3.939PheGly: 3.939 ± 0.05	0.826PheHis: 0.826 ± 0.022	1.836PheIle: 1.836 ± 0.034	1.296PheLys: 1.296 ± 0.028	4.154PheLeu: 4.154 ± 0.053	0.915PheMet: 0.915 ± 0.024	1.271PheAsn: 1.271 ± 0.027	1.719PhePro: 1.719 ± 0.03	1.304PheGln: 1.304 ± 0.025	2.253PheArg: 2.253 ± 0.037	2.763PheSer: 2.763 ± 0.043	2.017PheThr: 2.017 ± 0.033	3.196PheVal: 3.196 ± 0.035	0.643PheTrp: 0.643 ± 0.02	0.983PheTyr: 0.983 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	8.019GlyAla: 8.019 ± 0.072	0.855GlyCys: 0.855 ± 0.02	4.528GlyAsp: 4.528 ± 0.059	4.718GlyGlu: 4.718 ± 0.051	3.872GlyPhe: 3.872 ± 0.042	6.885GlyGly: 6.885 ± 0.09	1.903GlyHis: 1.903 ± 0.031	4.803GlyIle: 4.803 ± 0.062	3.561GlyLys: 3.561 ± 0.041	8.779GlyLeu: 8.779 ± 0.085	2.218GlyMet: 2.218 ± 0.037	2.731GlyAsn: 2.731 ± 0.052	3.256GlyPro: 3.256 ± 0.041	2.836GlyGln: 2.836 ± 0.04	5.016GlyArg: 5.016 ± 0.052	5.028GlySer: 5.028 ± 0.055	4.662GlyThr: 4.662 ± 0.051	5.907GlyVal: 5.907 ± 0.06	1.277GlyTrp: 1.277 ± 0.026	2.451GlyTyr: 2.451 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	1.918HisAla: 1.918 ± 0.035	0.246HisCys: 0.246 ± 0.012	1.263HisAsp: 1.263 ± 0.024	1.181HisGlu: 1.181 ± 0.024	0.913HisPhe: 0.913 ± 0.021	1.798HisGly: 1.798 ± 0.029	0.56HisHis: 0.56 ± 0.018	0.991HisIle: 0.991 ± 0.024	0.637HisLys: 0.637 ± 0.019	2.157HisLeu: 2.157 ± 0.035	0.533HisMet: 0.533 ± 0.018	0.515HisAsn: 0.515 ± 0.017	1.249HisPro: 1.249 ± 0.027	0.642HisGln: 0.642 ± 0.019	1.251HisArg: 1.251 ± 0.027	1.06HisSer: 1.06 ± 0.021	0.889HisThr: 0.889 ± 0.02	1.512HisVal: 1.512 ± 0.028	0.329HisTrp: 0.329 ± 0.012	0.538HisTyr: 0.538 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	6.867IleAla: 6.867 ± 0.07	0.69IleCys: 0.69 ± 0.022	3.699IleAsp: 3.699 ± 0.051	3.7IleGlu: 3.7 ± 0.046	2.002IlePhe: 2.002 ± 0.04	5.138IleGly: 5.138 ± 0.057	0.986IleHis: 0.986 ± 0.022	2.41IleIle: 2.41 ± 0.038	1.586IleLys: 1.586 ± 0.032	5.245IleLeu: 5.245 ± 0.058	1.115IleMet: 1.115 ± 0.025	1.559IleAsn: 1.559 ± 0.029	2.471IlePro: 2.471 ± 0.033	1.414IleGln: 1.414 ± 0.03	3.326IleArg: 3.326 ± 0.038	3.632IleSer: 3.632 ± 0.046	2.809IleThr: 2.809 ± 0.04	4.412IleVal: 4.412 ± 0.053	0.714IleTrp: 0.714 ± 0.02	1.31IleTyr: 1.31 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.098LysAla: 4.098 ± 0.051	0.231LysCys: 0.231 ± 0.01	2.165LysAsp: 2.165 ± 0.035	2.044LysGlu: 2.044 ± 0.034	1.174LysPhe: 1.174 ± 0.026	2.79LysGly: 2.79 ± 0.038	0.707LysHis: 0.707 ± 0.019	2.246LysIle: 2.246 ± 0.034	1.582LysLys: 1.582 ± 0.033	3.695LysLeu: 3.695 ± 0.05	0.899LysMet: 0.899 ± 0.024	1.257LysAsn: 1.257 ± 0.025	2.022LysPro: 2.022 ± 0.039	1.189LysGln: 1.189 ± 0.026	2.476LysArg: 2.476 ± 0.038	2.548LysSer: 2.548 ± 0.041	2.44LysThr: 2.44 ± 0.035	2.737LysVal: 2.737 ± 0.038	0.431LysTrp: 0.431 ± 0.016	0.734LysTyr: 0.734 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	11.639LeuAla: 11.639 ± 0.096	1.005LeuCys: 1.005 ± 0.023	5.957LeuAsp: 5.957 ± 0.059	6.318LeuGlu: 6.318 ± 0.061	4.056LeuPhe: 4.056 ± 0.053	8.007LeuGly: 8.007 ± 0.074	1.826LeuHis: 1.826 ± 0.031	5.333LeuIle: 5.333 ± 0.06	4.375LeuLys: 4.375 ± 0.052	9.489LeuLeu: 9.489 ± 0.097	2.422LeuMet: 2.422 ± 0.036	3.17LeuAsn: 3.17 ± 0.043	5.312LeuPro: 5.312 ± 0.062	3.097LeuGln: 3.097 ± 0.037	5.757LeuArg: 5.757 ± 0.065	7.251LeuSer: 7.251 ± 0.068	5.736LeuThr: 5.736 ± 0.06	7.522LeuVal: 7.522 ± 0.074	1.093LeuTrp: 1.093 ± 0.025	2.061LeuTyr: 2.061 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	2.72MetAla: 2.72 ± 0.043	0.192MetCys: 0.192 ± 0.009	1.25MetAsp: 1.25 ± 0.026	1.31MetGlu: 1.31 ± 0.031	0.814MetPhe: 0.814 ± 0.02	1.747MetGly: 1.747 ± 0.034	0.46MetHis: 0.46 ± 0.014	1.553MetIle: 1.553 ± 0.031	1.167MetLys: 1.167 ± 0.023	2.345MetLeu: 2.345 ± 0.037	0.697MetMet: 0.697 ± 0.021	0.923MetAsn: 0.923 ± 0.021	1.361MetPro: 1.361 ± 0.03	0.832MetGln: 0.832 ± 0.022	1.642MetArg: 1.642 ± 0.03	1.904MetSer: 1.904 ± 0.032	1.964MetThr: 1.964 ± 0.03	1.687MetVal: 1.687 ± 0.033	0.229MetTrp: 0.229 ± 0.011	0.347MetTyr: 0.347 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.357AsnAla: 3.357 ± 0.039	0.314AsnCys: 0.314 ± 0.013	1.765AsnAsp: 1.765 ± 0.038	1.651AsnGlu: 1.651 ± 0.026	1.184AsnPhe: 1.184 ± 0.025	2.808AsnGly: 2.808 ± 0.05	0.616AsnHis: 0.616 ± 0.019	1.654AsnIle: 1.654 ± 0.029	0.991AsnLys: 0.991 ± 0.023	3.069AsnLeu: 3.069 ± 0.036	0.793AsnMet: 0.793 ± 0.021	0.92AsnAsn: 0.92 ± 0.026	1.993AsnPro: 1.993 ± 0.03	0.948AsnGln: 0.948 ± 0.021	2.078AsnArg: 2.078 ± 0.032	1.781AsnSer: 1.781 ± 0.035	1.558AsnThr: 1.558 ± 0.027	2.282AsnVal: 2.282 ± 0.035	0.553AsnTrp: 0.553 ± 0.019	0.813AsnTyr: 0.813 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	4.803ProAla: 4.803 ± 0.05	0.319ProCys: 0.319 ± 0.013	3.827ProAsp: 3.827 ± 0.05	3.79ProGlu: 3.79 ± 0.05	2.104ProPhe: 2.104 ± 0.034	4.173ProGly: 4.173 ± 0.052	1.01ProHis: 1.01 ± 0.023	2.304ProIle: 2.304 ± 0.033	1.739ProLys: 1.739 ± 0.031	4.332ProLeu: 4.332 ± 0.049	1.084ProMet: 1.084 ± 0.024	1.414ProAsn: 1.414 ± 0.029	1.963ProPro: 1.963 ± 0.04	1.56ProGln: 1.56 ± 0.031	2.27ProArg: 2.27 ± 0.035	2.693ProSer: 2.693 ± 0.041	2.26ProThr: 2.26 ± 0.035	4.331ProVal: 4.331 ± 0.048	0.592ProTrp: 0.592 ± 0.019	1.167ProTyr: 1.167 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.49GlnAla: 3.49 ± 0.045	0.24GlnCys: 0.24 ± 0.01	1.804GlnAsp: 1.804 ± 0.03	1.913GlnGlu: 1.913 ± 0.037	1.192GlnPhe: 1.192 ± 0.021	2.262GlnGly: 2.262 ± 0.036	0.621GlnHis: 0.621 ± 0.018	2.045GlnIle: 2.045 ± 0.034	1.377GlnLys: 1.377 ± 0.029	2.98GlnLeu: 2.98 ± 0.05	0.923GlnMet: 0.923 ± 0.021	1.096GlnAsn: 1.096 ± 0.024	1.517GlnPro: 1.517 ± 0.034	1.202GlnGln: 1.202 ± 0.031	2.062GlnArg: 2.062 ± 0.032	2.104GlnSer: 2.104 ± 0.031	1.954GlnThr: 1.954 ± 0.036	2.337GlnVal: 2.337 ± 0.033	0.352GlnTrp: 0.352 ± 0.013	0.626GlnTyr: 0.626 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.698ArgAla: 5.698 ± 0.06	0.502ArgCys: 0.502 ± 0.017	3.575ArgAsp: 3.575 ± 0.043	3.849ArgGlu: 3.849 ± 0.053	2.78ArgPhe: 2.78 ± 0.039	3.931ArgGly: 3.931 ± 0.04	1.451ArgHis: 1.451 ± 0.029	3.775ArgIle: 3.775 ± 0.046	2.727ArgLys: 2.727 ± 0.042	6.803ArgLeu: 6.803 ± 0.068	1.692ArgMet: 1.692 ± 0.026	2.059ArgAsn: 2.059 ± 0.037	2.8ArgPro: 2.8 ± 0.036	2.416ArgGln: 2.416 ± 0.036	4.261ArgArg: 4.261 ± 0.059	3.826ArgSer: 3.826 ± 0.051	3.161ArgThr: 3.161 ± 0.039	3.99ArgVal: 3.99 ± 0.051	0.803ArgTrp: 0.803 ± 0.022	1.501ArgTyr: 1.501 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	6.27SerAla: 6.27 ± 0.066	0.525SerCys: 0.525 ± 0.015	3.791SerAsp: 3.791 ± 0.049	3.74SerGlu: 3.74 ± 0.049	2.693SerPhe: 2.693 ± 0.034	6.134SerGly: 6.134 ± 0.063	1.203SerHis: 1.203 ± 0.026	3.175SerIle: 3.175 ± 0.045	2.053SerLys: 2.053 ± 0.035	6.011SerLeu: 6.011 ± 0.072	1.488SerMet: 1.488 ± 0.029	1.916SerAsn: 1.916 ± 0.035	2.761SerPro: 2.761 ± 0.035	1.837SerGln: 1.837 ± 0.035	3.727SerArg: 3.727 ± 0.046	3.724SerSer: 3.724 ± 0.055	2.909SerThr: 2.909 ± 0.042	4.552SerVal: 4.552 ± 0.05	0.824SerTrp: 0.824 ± 0.021	1.414SerTyr: 1.414 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.762ThrAla: 5.762 ± 0.05	0.503ThrCys: 0.503 ± 0.014	3.109ThrAsp: 3.109 ± 0.044	3.002ThrGlu: 3.002 ± 0.04	2.267ThrPhe: 2.267 ± 0.036	5.441ThrGly: 5.441 ± 0.06	1.061ThrHis: 1.061 ± 0.024	3.081ThrIle: 3.081 ± 0.044	1.647ThrLys: 1.647 ± 0.028	5.794ThrLeu: 5.794 ± 0.051	1.254ThrMet: 1.254 ± 0.027	1.509ThrAsn: 1.509 ± 0.028	2.989ThrPro: 2.989 ± 0.036	1.504ThrGln: 1.504 ± 0.028	3.139ThrArg: 3.139 ± 0.04	3.293ThrSer: 3.293 ± 0.044	2.715ThrThr: 2.715 ± 0.038	4.34ThrVal: 4.34 ± 0.055	0.709ThrTrp: 0.709 ± 0.017	1.32ThrTyr: 1.32 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	7.99ValAla: 7.99 ± 0.075	0.734ValCys: 0.734 ± 0.019	4.276ValAsp: 4.276 ± 0.045	4.593ValGlu: 4.593 ± 0.055	3.285ValPhe: 3.285 ± 0.046	5.317ValGly: 5.317 ± 0.054	1.394ValHis: 1.394 ± 0.03	4.067ValIle: 4.067 ± 0.045	2.424ValLys: 2.424 ± 0.037	7.717ValLeu: 7.717 ± 0.067	1.856ValMet: 1.856 ± 0.033	2.209ValAsn: 2.209 ± 0.035	3.643ValPro: 3.643 ± 0.046	2.132ValGln: 2.132 ± 0.033	4.275ValArg: 4.275 ± 0.048	5.208ValSer: 5.208 ± 0.057	4.41ValThr: 4.41 ± 0.052	5.59ValVal: 5.59 ± 0.062	0.922ValTrp: 0.922 ± 0.022	1.582ValTyr: 1.582 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.074TrpAla: 1.074 ± 0.022	0.136TrpCys: 0.136 ± 0.008	0.691TrpAsp: 0.691 ± 0.021	0.605TrpGlu: 0.605 ± 0.018	0.598TrpPhe: 0.598 ± 0.018	0.892TrpGly: 0.892 ± 0.019	0.321TrpHis: 0.321 ± 0.014	0.758TrpIle: 0.758 ± 0.02	0.548TrpLys: 0.548 ± 0.018	1.549TrpLeu: 1.549 ± 0.033	0.372TrpMet: 0.372 ± 0.014	0.51TrpAsn: 0.51 ± 0.017	0.664TrpPro: 0.664 ± 0.018	0.595TrpGln: 0.595 ± 0.017	0.916TrpArg: 0.916 ± 0.022	0.874TrpSer: 0.874 ± 0.022	0.755TrpThr: 0.755 ± 0.018	0.823TrpVal: 0.823 ± 0.021	0.221TrpTrp: 0.221 ± 0.012	0.304TrpTyr: 0.304 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.296TyrAla: 2.296 ± 0.033	0.295TyrCys: 0.295 ± 0.011	1.454TyrAsp: 1.454 ± 0.029	1.34TyrGlu: 1.34 ± 0.029	1.07TyrPhe: 1.07 ± 0.023	2.061TyrGly: 2.061 ± 0.037	0.488TyrHis: 0.488 ± 0.018	0.986TyrIle: 0.986 ± 0.025	0.779TyrLys: 0.779 ± 0.021	2.452TyrLeu: 2.452 ± 0.04	0.494TyrMet: 0.494 ± 0.016	0.655TyrAsn: 0.655 ± 0.018	1.12TyrPro: 1.12 ± 0.026	0.814TyrGln: 0.814 ± 0.023	1.594TyrArg: 1.594 ± 0.027	1.421TyrSer: 1.421 ± 0.029	1.111TyrThr: 1.111 ± 0.023	1.623TyrVal: 1.623 ± 0.027	0.382TyrTrp: 0.382 ± 0.014	0.631TyrTyr: 0.631 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6265 proteins (2028616 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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