Amino acid dipepetide frequency for Chitinophaga rupis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.822AlaAla: 9.822 ± 0.1	0.856AlaCys: 0.856 ± 0.021	4.634AlaAsp: 4.634 ± 0.062	4.004AlaGlu: 4.004 ± 0.047	3.715AlaPhe: 3.715 ± 0.037	7.127AlaGly: 7.127 ± 0.077	1.541AlaHis: 1.541 ± 0.03	5.147AlaIle: 5.147 ± 0.053	3.912AlaLys: 3.912 ± 0.05	8.025AlaLeu: 8.025 ± 0.066	1.954AlaMet: 1.954 ± 0.031	3.89AlaAsn: 3.89 ± 0.06	3.411AlaPro: 3.411 ± 0.045	3.567AlaGln: 3.567 ± 0.037	3.331AlaArg: 3.331 ± 0.04	4.536AlaSer: 4.536 ± 0.048	5.108AlaThr: 5.108 ± 0.07	5.671AlaVal: 5.671 ± 0.053	1.044AlaTrp: 1.044 ± 0.023	3.362AlaTyr: 3.362 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.615CysAla: 0.615 ± 0.018	0.175CysCys: 0.175 ± 0.009	0.369CysAsp: 0.369 ± 0.013	0.369CysGlu: 0.369 ± 0.013	0.43CysPhe: 0.43 ± 0.014	0.653CysGly: 0.653 ± 0.021	0.21CysHis: 0.21 ± 0.009	0.647CysIle: 0.647 ± 0.019	0.449CysLys: 0.449 ± 0.015	0.853CysLeu: 0.853 ± 0.019	0.245CysMet: 0.245 ± 0.01	0.445CysAsn: 0.445 ± 0.017	0.365CysPro: 0.365 ± 0.015	0.242CysGln: 0.242 ± 0.011	0.425CysArg: 0.425 ± 0.014	0.57CysSer: 0.57 ± 0.017	0.564CysThr: 0.564 ± 0.024	0.471CysVal: 0.471 ± 0.013	0.133CysTrp: 0.133 ± 0.008	0.387CysTyr: 0.387 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.396AspAla: 4.396 ± 0.05	0.391AspCys: 0.391 ± 0.012	2.403AspAsp: 2.403 ± 0.045	2.808AspGlu: 2.808 ± 0.043	2.549AspPhe: 2.549 ± 0.034	3.789AspGly: 3.789 ± 0.044	1.144AspHis: 1.144 ± 0.025	3.524AspIle: 3.524 ± 0.038	3.137AspLys: 3.137 ± 0.042	4.635AspLeu: 4.635 ± 0.049	1.174AspMet: 1.174 ± 0.021	2.691AspAsn: 2.691 ± 0.038	2.403AspPro: 2.403 ± 0.036	1.823AspGln: 1.823 ± 0.033	2.082AspArg: 2.082 ± 0.032	2.853AspSer: 2.853 ± 0.046	2.923AspThr: 2.923 ± 0.046	3.305AspVal: 3.305 ± 0.043	0.78AspTrp: 0.78 ± 0.019	2.467AspTyr: 2.467 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	4.245GluAla: 4.245 ± 0.051	0.358GluCys: 0.358 ± 0.012	2.453GluAsp: 2.453 ± 0.038	3.249GluGlu: 3.249 ± 0.054	1.876GluPhe: 1.876 ± 0.029	3.28GluGly: 3.28 ± 0.036	1.183GluHis: 1.183 ± 0.024	3.419GluIle: 3.419 ± 0.044	4.152GluLys: 4.152 ± 0.056	5.099GluLeu: 5.099 ± 0.055	1.399GluMet: 1.399 ± 0.026	2.657GluAsn: 2.657 ± 0.035	1.671GluPro: 1.671 ± 0.033	2.784GluGln: 2.784 ± 0.039	2.469GluArg: 2.469 ± 0.033	2.303GluSer: 2.303 ± 0.034	2.646GluThr: 2.646 ± 0.04	3.437GluVal: 3.437 ± 0.047	0.712GluTrp: 0.712 ± 0.016	1.946GluTyr: 1.946 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.214PheAla: 3.214 ± 0.036	0.435PheCys: 0.435 ± 0.014	2.52PheAsp: 2.52 ± 0.034	2.32PheGlu: 2.32 ± 0.03	2.265PhePhe: 2.265 ± 0.035	3.009PheGly: 3.009 ± 0.036	0.901PheHis: 0.901 ± 0.02	3.022PheIle: 3.022 ± 0.037	2.512PheLys: 2.512 ± 0.033	4.005PheLeu: 4.005 ± 0.055	1.145PheMet: 1.145 ± 0.02	2.754PheAsn: 2.754 ± 0.04	1.81PhePro: 1.81 ± 0.028	1.377PheGln: 1.377 ± 0.025	2.149PheArg: 2.149 ± 0.028	3.388PheSer: 3.388 ± 0.037	3.325PheThr: 3.325 ± 0.053	2.511PheVal: 2.511 ± 0.033	0.543PheTrp: 0.543 ± 0.017	1.992PheTyr: 1.992 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	5.568GlyAla: 5.568 ± 0.058	0.718GlyCys: 0.718 ± 0.026	3.335GlyAsp: 3.335 ± 0.037	3.223GlyGlu: 3.223 ± 0.037	3.391GlyPhe: 3.391 ± 0.045	5.294GlyGly: 5.294 ± 0.077	1.383GlyHis: 1.383 ± 0.024	5.245GlyIle: 5.245 ± 0.052	4.841GlyLys: 4.841 ± 0.051	6.261GlyLeu: 6.261 ± 0.056	1.845GlyMet: 1.845 ± 0.031	3.958GlyAsn: 3.958 ± 0.047	2.002GlyPro: 2.002 ± 0.035	2.757GlyGln: 2.757 ± 0.037	3.065GlyArg: 3.065 ± 0.035	4.528GlySer: 4.528 ± 0.058	4.77GlyThr: 4.77 ± 0.08	4.589GlyVal: 4.589 ± 0.049	1.179GlyTrp: 1.179 ± 0.025	3.27GlyTyr: 3.27 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	1.564HisAla: 1.564 ± 0.028	0.237HisCys: 0.237 ± 0.011	0.886HisAsp: 0.886 ± 0.019	0.984HisGlu: 0.984 ± 0.021	1.248HisPhe: 1.248 ± 0.025	1.215HisGly: 1.215 ± 0.029	0.621HisHis: 0.621 ± 0.016	1.498HisIle: 1.498 ± 0.027	0.994HisLys: 0.994 ± 0.024	2.092HisLeu: 2.092 ± 0.033	0.469HisMet: 0.469 ± 0.014	1.04HisAsn: 1.04 ± 0.02	1.184HisPro: 1.184 ± 0.026	0.836HisGln: 0.836 ± 0.02	0.905HisArg: 0.905 ± 0.02	1.121HisSer: 1.121 ± 0.021	1.369HisThr: 1.369 ± 0.026	1.078HisVal: 1.078 ± 0.023	0.325HisTrp: 0.325 ± 0.011	1.057HisTyr: 1.057 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.58IleAla: 5.58 ± 0.057	0.659IleCys: 0.659 ± 0.016	3.389IleAsp: 3.389 ± 0.034	3.077IleGlu: 3.077 ± 0.047	2.643IlePhe: 2.643 ± 0.038	4.351IleGly: 4.351 ± 0.047	1.339IleHis: 1.339 ± 0.025	4.268IleIle: 4.268 ± 0.05	3.678IleLys: 3.678 ± 0.043	5.372IleLeu: 5.372 ± 0.056	1.338IleMet: 1.338 ± 0.024	3.399IleAsn: 3.399 ± 0.04	3.189IlePro: 3.189 ± 0.036	2.437IleGln: 2.437 ± 0.031	3.226IleArg: 3.226 ± 0.038	4.402IleSer: 4.402 ± 0.047	4.961IleThr: 4.961 ± 0.071	3.71IleVal: 3.71 ± 0.046	0.702IleTrp: 0.702 ± 0.018	2.469IleTyr: 2.469 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.885LysAla: 4.885 ± 0.056	0.278LysCys: 0.278 ± 0.011	3.659LysAsp: 3.659 ± 0.043	3.946LysGlu: 3.946 ± 0.05	1.85LysPhe: 1.85 ± 0.027	4.292LysGly: 4.292 ± 0.048	1.154LysHis: 1.154 ± 0.025	3.646LysIle: 3.646 ± 0.042	4.057LysLys: 4.057 ± 0.058	4.981LysLeu: 4.981 ± 0.048	1.621LysMet: 1.621 ± 0.025	2.922LysAsn: 2.922 ± 0.039	2.504LysPro: 2.504 ± 0.038	2.804LysGln: 2.804 ± 0.036	2.52LysArg: 2.52 ± 0.033	2.623LysSer: 2.623 ± 0.035	3.456LysThr: 3.456 ± 0.038	3.835LysVal: 3.835 ± 0.038	0.766LysTrp: 0.766 ± 0.02	2.344LysTyr: 2.344 ± 0.038	0.0LysXaa: 0.0 ± 0.0
Leu	7.49LeuAla: 7.49 ± 0.065	0.964LeuCys: 0.964 ± 0.021	4.669LeuAsp: 4.669 ± 0.046	4.886LeuGlu: 4.886 ± 0.055	4.385LeuPhe: 4.385 ± 0.052	5.829LeuGly: 5.829 ± 0.061	2.151LeuHis: 2.151 ± 0.034	5.264LeuIle: 5.264 ± 0.058	5.829LeuLys: 5.829 ± 0.054	10.859LeuLeu: 10.859 ± 0.102	2.135LeuMet: 2.135 ± 0.033	4.839LeuAsn: 4.839 ± 0.049	4.879LeuPro: 4.879 ± 0.05	5.624LeuGln: 5.624 ± 0.074	4.242LeuArg: 4.242 ± 0.045	6.457LeuSer: 6.457 ± 0.055	5.582LeuThr: 5.582 ± 0.057	5.751LeuVal: 5.751 ± 0.06	1.098LeuTrp: 1.098 ± 0.024	3.595LeuTyr: 3.595 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	1.963MetAla: 1.963 ± 0.032	0.16MetCys: 0.16 ± 0.008	1.302MetAsp: 1.302 ± 0.021	1.473MetGlu: 1.473 ± 0.028	0.779MetPhe: 0.779 ± 0.018	1.538MetGly: 1.538 ± 0.027	0.515MetHis: 0.515 ± 0.015	1.406MetIle: 1.406 ± 0.028	1.681MetLys: 1.681 ± 0.03	2.39MetLeu: 2.39 ± 0.034	0.577MetMet: 0.577 ± 0.017	1.251MetAsn: 1.251 ± 0.023	1.215MetPro: 1.215 ± 0.022	1.38MetGln: 1.38 ± 0.025	1.118MetArg: 1.118 ± 0.021	1.262MetSer: 1.262 ± 0.024	1.084MetThr: 1.084 ± 0.023	1.44MetVal: 1.44 ± 0.023	0.211MetTrp: 0.211 ± 0.009	0.725MetTyr: 0.725 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	4.204AsnAla: 4.204 ± 0.046	0.376AsnCys: 0.376 ± 0.015	2.574AsnAsp: 2.574 ± 0.034	2.507AsnGlu: 2.507 ± 0.034	2.22AsnPhe: 2.22 ± 0.037	4.445AsnGly: 4.445 ± 0.06	0.85AsnHis: 0.85 ± 0.02	3.88AsnIle: 3.88 ± 0.047	2.89AsnLys: 2.89 ± 0.036	4.317AsnLeu: 4.317 ± 0.049	1.2AsnMet: 1.2 ± 0.023	3.153AsnAsn: 3.153 ± 0.044	2.527AsnPro: 2.527 ± 0.037	1.698AsnGln: 1.698 ± 0.032	2.356AsnArg: 2.356 ± 0.037	2.854AsnSer: 2.854 ± 0.044	3.55AsnThr: 3.55 ± 0.054	3.139AsnVal: 3.139 ± 0.045	0.712AsnTrp: 0.712 ± 0.019	2.357AsnTyr: 2.357 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	4.94ProAla: 4.94 ± 0.067	0.261ProCys: 0.261 ± 0.009	2.88ProAsp: 2.88 ± 0.037	2.862ProGlu: 2.862 ± 0.039	2.056ProPhe: 2.056 ± 0.031	3.648ProGly: 3.648 ± 0.04	0.83ProHis: 0.83 ± 0.018	2.059ProIle: 2.059 ± 0.028	1.793ProLys: 1.793 ± 0.03	4.121ProLeu: 4.121 ± 0.049	0.829ProMet: 0.829 ± 0.019	1.84ProAsn: 1.84 ± 0.03	1.547ProPro: 1.547 ± 0.032	1.748ProGln: 1.748 ± 0.028	1.434ProArg: 1.434 ± 0.028	2.173ProSer: 2.173 ± 0.031	2.016ProThr: 2.016 ± 0.041	4.113ProVal: 4.113 ± 0.054	0.553ProTrp: 0.553 ± 0.017	1.775ProTyr: 1.775 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.466GlnAla: 3.466 ± 0.04	0.279GlnCys: 0.279 ± 0.011	1.975GlnAsp: 1.975 ± 0.028	2.46GlnGlu: 2.46 ± 0.034	1.785GlnPhe: 1.785 ± 0.033	2.475GlnGly: 2.475 ± 0.031	1.282GlnHis: 1.282 ± 0.025	2.091GlnIle: 2.091 ± 0.029	2.329GlnLys: 2.329 ± 0.03	5.155GlnLeu: 5.155 ± 0.064	0.964GlnMet: 0.964 ± 0.024	1.786GlnAsn: 1.786 ± 0.029	2.289GlnPro: 2.289 ± 0.031	3.62GlnGln: 3.62 ± 0.057	2.039GlnArg: 2.039 ± 0.032	2.202GlnSer: 2.202 ± 0.032	2.315GlnThr: 2.315 ± 0.032	3.038GlnVal: 3.038 ± 0.036	0.638GlnTrp: 0.638 ± 0.017	1.979GlnTyr: 1.979 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.839ArgAla: 2.839 ± 0.036	0.291ArgCys: 0.291 ± 0.011	2.06ArgAsp: 2.06 ± 0.031	2.446ArgGlu: 2.446 ± 0.037	2.287ArgPhe: 2.287 ± 0.033	2.291ArgGly: 2.291 ± 0.034	0.914ArgHis: 0.914 ± 0.024	3.27ArgIle: 3.27 ± 0.035	2.843ArgLys: 2.843 ± 0.038	4.5ArgLeu: 4.5 ± 0.046	1.231ArgMet: 1.231 ± 0.024	2.455ArgAsn: 2.455 ± 0.04	1.621ArgPro: 1.621 ± 0.029	2.052ArgGln: 2.052 ± 0.035	1.954ArgArg: 1.954 ± 0.035	2.645ArgSer: 2.645 ± 0.037	2.534ArgThr: 2.534 ± 0.032	2.699ArgVal: 2.699 ± 0.037	0.74ArgTrp: 0.74 ± 0.023	2.163ArgTyr: 2.163 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	4.7SerAla: 4.7 ± 0.05	0.595SerCys: 0.595 ± 0.016	2.653SerAsp: 2.653 ± 0.037	2.391SerGlu: 2.391 ± 0.034	3.221SerPhe: 3.221 ± 0.039	4.96SerGly: 4.96 ± 0.048	1.052SerHis: 1.052 ± 0.021	3.961SerIle: 3.961 ± 0.036	2.946SerLys: 2.946 ± 0.04	5.917SerLeu: 5.917 ± 0.053	1.365SerMet: 1.365 ± 0.024	2.933SerAsn: 2.933 ± 0.04	2.384SerPro: 2.384 ± 0.035	1.969SerGln: 1.969 ± 0.029	2.686SerArg: 2.686 ± 0.034	3.776SerSer: 3.776 ± 0.05	3.663SerThr: 3.663 ± 0.049	3.834SerVal: 3.834 ± 0.058	0.928SerTrp: 0.928 ± 0.021	2.712SerTyr: 2.712 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	6.057ThrAla: 6.057 ± 0.081	0.467ThrCys: 0.467 ± 0.017	3.454ThrAsp: 3.454 ± 0.058	2.644ThrGlu: 2.644 ± 0.036	2.838ThrPhe: 2.838 ± 0.04	5.674ThrGly: 5.674 ± 0.079	1.148ThrHis: 1.148 ± 0.022	4.142ThrIle: 4.142 ± 0.059	2.582ThrLys: 2.582 ± 0.032	6.118ThrLeu: 6.118 ± 0.056	1.063ThrMet: 1.063 ± 0.02	2.763ThrAsn: 2.763 ± 0.046	3.238ThrPro: 3.238 ± 0.06	2.245ThrGln: 2.245 ± 0.038	2.455ThrArg: 2.455 ± 0.037	3.441ThrSer: 3.441 ± 0.064	3.959ThrThr: 3.959 ± 0.073	4.541ThrVal: 4.541 ± 0.08	0.836ThrTrp: 0.836 ± 0.023	2.514ThrTyr: 2.514 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	5.027ValAla: 5.027 ± 0.051	0.61ValCys: 0.61 ± 0.017	3.007ValAsp: 3.007 ± 0.037	2.864ValGlu: 2.864 ± 0.039	2.943ValPhe: 2.943 ± 0.037	3.498ValGly: 3.498 ± 0.044	1.265ValHis: 1.265 ± 0.024	4.49ValIle: 4.49 ± 0.046	4.256ValLys: 4.256 ± 0.044	6.489ValLeu: 6.489 ± 0.058	1.634ValMet: 1.634 ± 0.029	3.686ValAsn: 3.686 ± 0.044	2.94ValPro: 2.94 ± 0.04	2.712ValGln: 2.712 ± 0.031	2.574ValArg: 2.574 ± 0.034	4.238ValSer: 4.238 ± 0.05	4.618ValThr: 4.618 ± 0.081	4.293ValVal: 4.293 ± 0.053	0.776ValTrp: 0.776 ± 0.02	2.632ValTyr: 2.632 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	0.893TrpAla: 0.893 ± 0.022	0.12TrpCys: 0.12 ± 0.006	0.729TrpAsp: 0.729 ± 0.021	0.759TrpGlu: 0.759 ± 0.02	0.581TrpPhe: 0.581 ± 0.015	0.938TrpGly: 0.938 ± 0.021	0.31TrpHis: 0.31 ± 0.012	0.81TrpIle: 0.81 ± 0.021	0.874TrpLys: 0.874 ± 0.02	1.421TrpLeu: 1.421 ± 0.029	0.413TrpMet: 0.413 ± 0.015	0.756TrpAsn: 0.756 ± 0.019	0.426TrpPro: 0.426 ± 0.016	0.781TrpGln: 0.781 ± 0.019	0.598TrpArg: 0.598 ± 0.015	0.757TrpSer: 0.757 ± 0.018	0.773TrpThr: 0.773 ± 0.03	0.767TrpVal: 0.767 ± 0.02	0.285TrpTrp: 0.285 ± 0.011	0.588TrpTyr: 0.588 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.188TyrAla: 3.188 ± 0.037	0.391TyrCys: 0.391 ± 0.015	2.326TyrAsp: 2.326 ± 0.037	2.068TyrGlu: 2.068 ± 0.03	2.134TyrPhe: 2.134 ± 0.033	2.916TyrGly: 2.916 ± 0.036	0.928TyrHis: 0.928 ± 0.019	2.399TyrIle: 2.399 ± 0.032	2.39TyrLys: 2.39 ± 0.033	3.917TyrLeu: 3.917 ± 0.044	0.869TyrMet: 0.869 ± 0.019	2.59TyrAsn: 2.59 ± 0.036	1.875TyrPro: 1.875 ± 0.028	1.708TyrGln: 1.708 ± 0.027	2.209TyrArg: 2.209 ± 0.029	2.518TyrSer: 2.518 ± 0.035	2.961TyrThr: 2.961 ± 0.052	2.33TyrVal: 2.33 ± 0.033	0.618TyrTrp: 0.618 ± 0.017	2.045TyrTyr: 2.045 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 6498 proteins (2498919 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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