Amino acid dipepetide frequency for Hubei sobemo-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.444AlaAla: 3.444 ± 0.485
0.0AlaCys: 0.0 ± 0.0
4.592AlaAsp: 4.592 ± 2.279
2.296AlaGlu: 2.296 ± 1.493
4.592AlaPhe: 4.592 ± 2.987
1.148AlaGly: 1.148 ± 0.747
1.148AlaHis: 1.148 ± 0.747
1.148AlaIle: 1.148 ± 1.009
5.741AlaLys: 5.741 ± 1.533
9.185AlaLeu: 9.185 ± 0.707
2.296AlaMet: 2.296 ± 2.017
2.296AlaAsn: 2.296 ± 0.262
4.592AlaPro: 4.592 ± 2.987
2.296AlaGln: 2.296 ± 2.017
3.444AlaArg: 3.444 ± 0.485
4.592AlaSer: 4.592 ± 1.231
2.296AlaThr: 2.296 ± 1.493
3.444AlaVal: 3.444 ± 1.271
4.592AlaTrp: 4.592 ± 0.524
8.037AlaTyr: 8.037 ± 3.471
0.0AlaXaa: 0.0 ± 0.0
Cys
1.148CysAla: 1.148 ± 0.747
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.148CysPhe: 1.148 ± 1.009
1.148CysGly: 1.148 ± 0.747
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.296CysLys: 2.296 ± 0.262
2.296CysLeu: 2.296 ± 2.017
1.148CysMet: 1.148 ± 0.747
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.148CysGln: 1.148 ± 1.009
0.0CysArg: 0.0 ± 0.0
1.148CysSer: 1.148 ± 0.747
2.296CysThr: 2.296 ± 1.493
1.148CysVal: 1.148 ± 1.009
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.444AspAla: 3.444 ± 0.485
0.0AspCys: 0.0 ± 0.0
3.444AspAsp: 3.444 ± 1.271
2.296AspGlu: 2.296 ± 1.493
2.296AspPhe: 2.296 ± 1.493
4.592AspGly: 4.592 ± 0.524
0.0AspHis: 0.0 ± 0.0
1.148AspIle: 1.148 ± 1.009
3.444AspLys: 3.444 ± 1.271
2.296AspLeu: 2.296 ± 1.493
3.444AspMet: 3.444 ± 1.271
0.0AspAsn: 0.0 ± 0.0
2.296AspPro: 2.296 ± 1.493
0.0AspGln: 0.0 ± 0.0
3.444AspArg: 3.444 ± 1.271
5.741AspSer: 5.741 ± 0.223
3.444AspThr: 3.444 ± 0.485
4.592AspVal: 4.592 ± 0.524
1.148AspTrp: 1.148 ± 1.009
2.296AspTyr: 2.296 ± 1.493
0.0AspXaa: 0.0 ± 0.0
Glu
5.741GluAla: 5.741 ± 1.978
0.0GluCys: 0.0 ± 0.0
6.889GluAsp: 6.889 ± 2.725
4.592GluGlu: 4.592 ± 0.524
3.444GluPhe: 3.444 ± 3.026
1.148GluGly: 1.148 ± 0.747
1.148GluHis: 1.148 ± 1.009
3.444GluIle: 3.444 ± 0.485
4.592GluLys: 4.592 ± 0.524
9.185GluLeu: 9.185 ± 2.803
0.0GluMet: 0.0 ± 0.0
1.148GluAsn: 1.148 ± 0.747
4.592GluPro: 4.592 ± 0.524
0.0GluGln: 0.0 ± 0.0
2.296GluArg: 2.296 ± 0.262
3.444GluSer: 3.444 ± 0.485
1.148GluThr: 1.148 ± 0.747
5.741GluVal: 5.741 ± 0.223
1.148GluTrp: 1.148 ± 1.009
1.148GluTyr: 1.148 ± 1.009
0.0GluXaa: 0.0 ± 0.0
Phe
5.741PheAla: 5.741 ± 1.533
1.148PheCys: 1.148 ± 0.747
1.148PheAsp: 1.148 ± 1.009
5.741PheGlu: 5.741 ± 1.533
2.296PhePhe: 2.296 ± 0.262
4.592PheGly: 4.592 ± 1.231
0.0PheHis: 0.0 ± 0.0
2.296PheIle: 2.296 ± 0.262
3.444PheLys: 3.444 ± 3.026
3.444PheLeu: 3.444 ± 1.271
0.0PheMet: 0.0 ± 0.0
1.148PheAsn: 1.148 ± 0.747
1.148PhePro: 1.148 ± 1.009
3.444PheGln: 3.444 ± 0.485
2.296PheArg: 2.296 ± 2.017
2.296PheSer: 2.296 ± 0.262
1.148PheThr: 1.148 ± 0.747
4.592PheVal: 4.592 ± 1.231
1.148PheTrp: 1.148 ± 0.747
1.148PheTyr: 1.148 ± 0.747
0.0PheXaa: 0.0 ± 0.0
Gly
2.296GlyAla: 2.296 ± 2.017
1.148GlyCys: 1.148 ± 1.009
1.148GlyAsp: 1.148 ± 1.009
1.148GlyGlu: 1.148 ± 1.009
6.889GlyPhe: 6.889 ± 0.969
4.592GlyGly: 4.592 ± 1.231
0.0GlyHis: 0.0 ± 0.0
2.296GlyIle: 2.296 ± 0.262
4.592GlyLys: 4.592 ± 0.524
10.333GlyLeu: 10.333 ± 3.209
1.148GlyMet: 1.148 ± 0.747
2.296GlyAsn: 2.296 ± 1.493
1.148GlyPro: 1.148 ± 1.009
2.296GlyGln: 2.296 ± 0.262
4.592GlyArg: 4.592 ± 0.524
5.741GlySer: 5.741 ± 3.733
3.444GlyThr: 3.444 ± 0.485
4.592GlyVal: 4.592 ± 0.524
4.592GlyTrp: 4.592 ± 2.279
2.296GlyTyr: 2.296 ± 1.493
0.0GlyXaa: 0.0 ± 0.0
His
1.148HisAla: 1.148 ± 0.747
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.148HisGly: 1.148 ± 1.009
1.148HisHis: 1.148 ± 0.747
1.148HisIle: 1.148 ± 0.747
1.148HisLys: 1.148 ± 1.009
2.296HisLeu: 2.296 ± 2.017
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.296HisArg: 2.296 ± 0.262
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.148HisVal: 1.148 ± 0.747
1.148HisTrp: 1.148 ± 1.009
2.296HisTyr: 2.296 ± 0.262
0.0HisXaa: 0.0 ± 0.0
Ile
3.444IleAla: 3.444 ± 2.24
0.0IleCys: 0.0 ± 0.0
1.148IleAsp: 1.148 ± 1.009
1.148IleGlu: 1.148 ± 1.009
1.148IlePhe: 1.148 ± 0.747
4.592IleGly: 4.592 ± 0.524
0.0IleHis: 0.0 ± 0.0
1.148IleIle: 1.148 ± 0.747
4.592IleLys: 4.592 ± 0.524
6.889IleLeu: 6.889 ± 0.786
3.444IleMet: 3.444 ± 1.271
1.148IleAsn: 1.148 ± 1.009
1.148IlePro: 1.148 ± 0.747
1.148IleGln: 1.148 ± 0.747
1.148IleArg: 1.148 ± 1.009
4.592IleSer: 4.592 ± 2.279
2.296IleThr: 2.296 ± 0.262
1.148IleVal: 1.148 ± 0.747
0.0IleTrp: 0.0 ± 0.0
1.148IleTyr: 1.148 ± 1.009
0.0IleXaa: 0.0 ± 0.0
Lys
4.592LysAla: 4.592 ± 2.279
0.0LysCys: 0.0 ± 0.0
3.444LysAsp: 3.444 ± 3.026
3.444LysGlu: 3.444 ± 1.271
2.296LysPhe: 2.296 ± 1.493
6.889LysGly: 6.889 ± 0.786
1.148LysHis: 1.148 ± 1.009
0.0LysIle: 0.0 ± 0.0
3.444LysLys: 3.444 ± 2.24
4.592LysLeu: 4.592 ± 1.231
5.741LysMet: 5.741 ± 0.223
2.296LysAsn: 2.296 ± 1.493
3.444LysPro: 3.444 ± 3.026
1.148LysGln: 1.148 ± 0.747
3.444LysArg: 3.444 ± 2.24
5.741LysSer: 5.741 ± 0.223
3.444LysThr: 3.444 ± 0.485
3.444LysVal: 3.444 ± 1.271
0.0LysTrp: 0.0 ± 0.0
4.592LysTyr: 4.592 ± 2.279
0.0LysXaa: 0.0 ± 0.0
Leu
8.037LeuAla: 8.037 ± 1.716
3.444LeuCys: 3.444 ± 0.485
3.444LeuAsp: 3.444 ± 0.485
8.037LeuGlu: 8.037 ± 0.039
5.741LeuPhe: 5.741 ± 1.533
8.037LeuGly: 8.037 ± 1.716
1.148LeuHis: 1.148 ± 1.009
6.889LeuIle: 6.889 ± 0.786
3.444LeuLys: 3.444 ± 0.485
9.185LeuLeu: 9.185 ± 2.463
2.296LeuMet: 2.296 ± 1.493
2.296LeuAsn: 2.296 ± 0.262
1.148LeuPro: 1.148 ± 0.747
5.741LeuGln: 5.741 ± 0.223
6.889LeuArg: 6.889 ± 0.786
3.444LeuSer: 3.444 ± 0.485
6.889LeuThr: 6.889 ± 0.786
8.037LeuVal: 8.037 ± 3.55
0.0LeuTrp: 0.0 ± 0.0
4.592LeuTyr: 4.592 ± 1.231
0.0LeuXaa: 0.0 ± 0.0
Met
6.889MetAla: 6.889 ± 0.969
0.0MetCys: 0.0 ± 0.0
2.296MetAsp: 2.296 ± 0.262
1.148MetGlu: 1.148 ± 0.747
3.444MetPhe: 3.444 ± 1.271
1.148MetGly: 1.148 ± 0.747
1.148MetHis: 1.148 ± 0.747
1.148MetIle: 1.148 ± 0.747
2.296MetLys: 2.296 ± 0.262
5.741MetLeu: 5.741 ± 1.533
0.0MetMet: 0.0 ± 0.0
1.148MetAsn: 1.148 ± 1.009
0.0MetPro: 0.0 ± 0.0
1.148MetGln: 1.148 ± 1.009
1.148MetArg: 1.148 ± 0.747
4.592MetSer: 4.592 ± 0.524
1.148MetThr: 1.148 ± 1.009
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.148AsnAla: 1.148 ± 1.009
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
2.296AsnGlu: 2.296 ± 0.262
0.0AsnPhe: 0.0 ± 0.0
1.148AsnGly: 1.148 ± 0.747
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
4.592AsnLeu: 4.592 ± 2.987
2.296AsnMet: 2.296 ± 1.185
2.296AsnAsn: 2.296 ± 1.493
3.444AsnPro: 3.444 ± 1.271
3.444AsnGln: 3.444 ± 1.271
1.148AsnArg: 1.148 ± 0.747
3.444AsnSer: 3.444 ± 0.485
1.148AsnThr: 1.148 ± 0.747
2.296AsnVal: 2.296 ± 1.493
0.0AsnTrp: 0.0 ± 0.0
1.148AsnTyr: 1.148 ± 1.009
0.0AsnXaa: 0.0 ± 0.0
Pro
5.741ProAla: 5.741 ± 1.978
1.148ProCys: 1.148 ± 1.009
2.296ProAsp: 2.296 ± 1.493
5.741ProGlu: 5.741 ± 3.288
0.0ProPhe: 0.0 ± 0.0
4.592ProGly: 4.592 ± 1.231
1.148ProHis: 1.148 ± 1.009
3.444ProIle: 3.444 ± 3.026
1.148ProLys: 1.148 ± 0.747
1.148ProLeu: 1.148 ± 0.747
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
1.148ProPro: 1.148 ± 0.747
4.592ProGln: 4.592 ± 2.987
1.148ProArg: 1.148 ± 0.747
1.148ProSer: 1.148 ± 0.747
2.296ProThr: 2.296 ± 0.262
5.741ProVal: 5.741 ± 1.533
0.0ProTrp: 0.0 ± 0.0
2.296ProTyr: 2.296 ± 1.493
0.0ProXaa: 0.0 ± 0.0
Gln
2.296GlnAla: 2.296 ± 1.493
1.148GlnCys: 1.148 ± 0.747
1.148GlnAsp: 1.148 ± 0.747
2.296GlnGlu: 2.296 ± 2.017
2.296GlnPhe: 2.296 ± 2.017
1.148GlnGly: 1.148 ± 1.009
0.0GlnHis: 0.0 ± 0.0
2.296GlnIle: 2.296 ± 2.017
3.444GlnLys: 3.444 ± 1.271
2.296GlnLeu: 2.296 ± 0.262
1.148GlnMet: 1.148 ± 1.009
0.0GlnAsn: 0.0 ± 0.0
2.296GlnPro: 2.296 ± 0.262
4.592GlnGln: 4.592 ± 0.524
1.148GlnArg: 1.148 ± 0.747
5.741GlnSer: 5.741 ± 0.223
3.444GlnThr: 3.444 ± 2.24
3.444GlnVal: 3.444 ± 2.24
1.148GlnTrp: 1.148 ± 0.747
3.444GlnTyr: 3.444 ± 1.271
0.0GlnXaa: 0.0 ± 0.0
Arg
1.148ArgAla: 1.148 ± 0.747
0.0ArgCys: 0.0 ± 0.0
3.444ArgAsp: 3.444 ± 0.485
3.444ArgGlu: 3.444 ± 1.271
5.741ArgPhe: 5.741 ± 1.533
2.296ArgGly: 2.296 ± 0.262
1.148ArgHis: 1.148 ± 1.009
4.592ArgIle: 4.592 ± 0.524
3.444ArgLys: 3.444 ± 0.485
6.889ArgLeu: 6.889 ± 0.786
1.148ArgMet: 1.148 ± 1.009
3.444ArgAsn: 3.444 ± 1.271
3.444ArgPro: 3.444 ± 0.485
1.148ArgGln: 1.148 ± 0.747
3.444ArgArg: 3.444 ± 0.485
3.444ArgSer: 3.444 ± 2.24
1.148ArgThr: 1.148 ± 0.747
4.592ArgVal: 4.592 ± 1.231
0.0ArgTrp: 0.0 ± 0.0
1.148ArgTyr: 1.148 ± 1.009
0.0ArgXaa: 0.0 ± 0.0
Ser
5.741SerAla: 5.741 ± 0.223
0.0SerCys: 0.0 ± 0.0
3.444SerAsp: 3.444 ± 2.24
4.592SerGlu: 4.592 ± 2.987
1.148SerPhe: 1.148 ± 1.009
8.037SerGly: 8.037 ± 1.716
1.148SerHis: 1.148 ± 1.009
2.296SerIle: 2.296 ± 1.493
3.444SerLys: 3.444 ± 2.24
3.444SerLeu: 3.444 ± 1.271
3.444SerMet: 3.444 ± 0.485
1.148SerAsn: 1.148 ± 0.747
6.889SerPro: 6.889 ± 0.969
2.296SerGln: 2.296 ± 1.493
6.889SerArg: 6.889 ± 0.786
6.889SerSer: 6.889 ± 0.786
3.444SerThr: 3.444 ± 2.24
3.444SerVal: 3.444 ± 1.271
2.296SerTrp: 2.296 ± 2.017
3.444SerTyr: 3.444 ± 1.271
0.0SerXaa: 0.0 ± 0.0
Thr
2.296ThrAla: 2.296 ± 0.262
0.0ThrCys: 0.0 ± 0.0
1.148ThrAsp: 1.148 ± 0.747
2.296ThrGlu: 2.296 ± 1.493
1.148ThrPhe: 1.148 ± 0.747
3.444ThrGly: 3.444 ± 0.485
1.148ThrHis: 1.148 ± 0.747
2.296ThrIle: 2.296 ± 1.493
3.444ThrLys: 3.444 ± 0.485
3.444ThrLeu: 3.444 ± 0.485
1.148ThrMet: 1.148 ± 0.747
4.592ThrAsn: 4.592 ± 1.231
5.741ThrPro: 5.741 ± 1.978
1.148ThrGln: 1.148 ± 1.009
1.148ThrArg: 1.148 ± 1.009
2.296ThrSer: 2.296 ± 1.493
2.296ThrThr: 2.296 ± 0.262
4.592ThrVal: 4.592 ± 0.524
0.0ThrTrp: 0.0 ± 0.0
1.148ThrTyr: 1.148 ± 0.747
0.0ThrXaa: 0.0 ± 0.0
Val
3.444ValAla: 3.444 ± 1.271
3.444ValCys: 3.444 ± 1.271
4.592ValAsp: 4.592 ± 0.524
6.889ValGlu: 6.889 ± 0.969
3.444ValPhe: 3.444 ± 1.271
4.592ValGly: 4.592 ± 4.035
2.296ValHis: 2.296 ± 0.262
1.148ValIle: 1.148 ± 0.747
4.592ValLys: 4.592 ± 0.524
4.592ValLeu: 4.592 ± 1.231
3.444ValMet: 3.444 ± 1.271
3.444ValAsn: 3.444 ± 0.485
2.296ValPro: 2.296 ± 0.262
3.444ValGln: 3.444 ± 1.271
5.741ValArg: 5.741 ± 0.223
4.592ValSer: 4.592 ± 0.524
1.148ValThr: 1.148 ± 0.747
5.741ValVal: 5.741 ± 1.533
3.444ValTrp: 3.444 ± 0.485
2.296ValTyr: 2.296 ± 1.493
0.0ValXaa: 0.0 ± 0.0
Trp
1.148TrpAla: 1.148 ± 0.747
2.296TrpCys: 2.296 ± 0.262
2.296TrpAsp: 2.296 ± 0.262
0.0TrpGlu: 0.0 ± 0.0
1.148TrpPhe: 1.148 ± 1.009
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.148TrpIle: 1.148 ± 1.009
1.148TrpLys: 1.148 ± 1.009
3.444TrpLeu: 3.444 ± 1.271
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.296TrpGln: 2.296 ± 0.262
1.148TrpArg: 1.148 ± 1.009
1.148TrpSer: 1.148 ± 1.009
2.296TrpThr: 2.296 ± 0.262
3.444TrpVal: 3.444 ± 1.271
1.148TrpTrp: 1.148 ± 1.009
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 0.262
1.148TyrCys: 1.148 ± 0.747
3.444TyrAsp: 3.444 ± 2.24
3.444TyrGlu: 3.444 ± 0.485
0.0TyrPhe: 0.0 ± 0.0
2.296TyrGly: 2.296 ± 0.262
1.148TyrHis: 1.148 ± 0.747
3.444TyrIle: 3.444 ± 1.271
3.444TyrLys: 3.444 ± 0.485
3.444TyrLeu: 3.444 ± 2.24
1.148TyrMet: 1.148 ± 0.455
1.148TyrAsn: 1.148 ± 0.747
0.0TyrPro: 0.0 ± 0.0
3.444TyrGln: 3.444 ± 1.271
2.296TyrArg: 2.296 ± 1.493
3.444TyrSer: 3.444 ± 0.485
0.0TyrThr: 0.0 ± 0.0
3.444TyrVal: 3.444 ± 1.271
2.296TyrTrp: 2.296 ± 2.017
3.444TyrTyr: 3.444 ± 2.24
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (872 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski