Amino acid dipepetide frequency for Penicillium janczewskii chrysovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.285AlaAla: 13.285 ± 2.111
1.812AlaCys: 1.812 ± 0.836
5.133AlaAsp: 5.133 ± 1.123
6.944AlaGlu: 6.944 ± 1.415
2.415AlaPhe: 2.415 ± 0.511
9.058AlaGly: 9.058 ± 2.317
1.812AlaHis: 1.812 ± 0.661
5.133AlaIle: 5.133 ± 0.609
3.321AlaLys: 3.321 ± 0.383
10.266AlaLeu: 10.266 ± 2.372
3.925AlaMet: 3.925 ± 1.077
4.227AlaAsn: 4.227 ± 0.425
6.341AlaPro: 6.341 ± 1.029
3.623AlaGln: 3.623 ± 0.853
8.756AlaArg: 8.756 ± 0.859
9.662AlaSer: 9.662 ± 1.513
7.246AlaThr: 7.246 ± 1.158
8.756AlaVal: 8.756 ± 0.473
0.906AlaTrp: 0.906 ± 0.53
3.925AlaTyr: 3.925 ± 0.926
0.0AlaXaa: 0.0 ± 0.0
Cys
3.019CysAla: 3.019 ± 0.931
0.302CysCys: 0.302 ± 0.219
1.208CysAsp: 1.208 ± 0.507
0.906CysGlu: 0.906 ± 0.203
0.302CysPhe: 0.302 ± 0.256
1.812CysGly: 1.812 ± 0.681
0.604CysHis: 0.604 ± 0.268
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.906CysLeu: 0.906 ± 0.658
0.302CysMet: 0.302 ± 0.219
0.302CysAsn: 0.302 ± 0.219
0.302CysPro: 0.302 ± 0.279
1.208CysGln: 1.208 ± 0.534
0.604CysArg: 0.604 ± 0.439
1.208CysSer: 1.208 ± 0.119
0.604CysThr: 0.604 ± 0.294
1.208CysVal: 1.208 ± 0.491
0.604CysTrp: 0.604 ± 0.512
0.302CysTyr: 0.302 ± 0.219
0.0CysXaa: 0.0 ± 0.0
Asp
6.643AspAla: 6.643 ± 1.037
1.208AspCys: 1.208 ± 0.286
2.415AspAsp: 2.415 ± 0.727
3.019AspGlu: 3.019 ± 0.568
0.906AspPhe: 0.906 ± 0.273
6.944AspGly: 6.944 ± 2.125
2.415AspHis: 2.415 ± 0.19
2.415AspIle: 2.415 ± 0.86
0.906AspLys: 0.906 ± 0.388
4.227AspLeu: 4.227 ± 1.093
0.906AspMet: 0.906 ± 0.334
2.114AspAsn: 2.114 ± 0.352
1.51AspPro: 1.51 ± 0.6
0.906AspGln: 0.906 ± 0.334
2.114AspArg: 2.114 ± 0.213
2.114AspSer: 2.114 ± 0.75
3.925AspThr: 3.925 ± 0.786
5.435AspVal: 5.435 ± 0.702
1.51AspTrp: 1.51 ± 0.628
2.415AspTyr: 2.415 ± 0.671
0.0AspXaa: 0.0 ± 0.0
Glu
7.246GluAla: 7.246 ± 1.48
1.51GluCys: 1.51 ± 0.411
2.415GluAsp: 2.415 ± 1.253
5.133GluGlu: 5.133 ± 1.138
3.019GluPhe: 3.019 ± 1.201
3.019GluGly: 3.019 ± 0.822
1.51GluHis: 1.51 ± 0.776
2.717GluIle: 2.717 ± 1.235
0.906GluLys: 0.906 ± 0.418
5.435GluLeu: 5.435 ± 0.146
0.906GluMet: 0.906 ± 0.281
0.906GluAsn: 0.906 ± 0.612
2.415GluPro: 2.415 ± 0.511
2.415GluGln: 2.415 ± 1.062
2.717GluArg: 2.717 ± 0.551
2.415GluSer: 2.415 ± 0.237
2.415GluThr: 2.415 ± 0.86
3.623GluVal: 3.623 ± 0.586
1.812GluTrp: 1.812 ± 0.543
0.906GluTyr: 0.906 ± 0.658
0.0GluXaa: 0.0 ± 0.0
Phe
4.529PheAla: 4.529 ± 0.612
0.302PheCys: 0.302 ± 0.219
1.812PheAsp: 1.812 ± 0.776
2.415PheGlu: 2.415 ± 0.671
1.208PhePhe: 1.208 ± 0.627
1.812PheGly: 1.812 ± 0.666
0.604PheHis: 0.604 ± 0.558
1.208PheIle: 1.208 ± 0.119
0.906PheLys: 0.906 ± 0.438
0.906PheLeu: 0.906 ± 0.768
0.604PheMet: 0.604 ± 0.439
0.604PheAsn: 0.604 ± 0.294
1.51PhePro: 1.51 ± 0.713
0.604PheGln: 0.604 ± 0.558
1.51PheArg: 1.51 ± 0.473
0.604PheSer: 0.604 ± 0.266
2.415PheThr: 2.415 ± 0.19
2.114PheVal: 2.114 ± 0.296
0.604PheTrp: 0.604 ± 0.335
0.302PheTyr: 0.302 ± 0.219
0.0PheXaa: 0.0 ± 0.0
Gly
11.171GlyAla: 11.171 ± 1.815
0.906GlyCys: 0.906 ± 0.438
3.321GlyAsp: 3.321 ± 0.855
3.925GlyGlu: 3.925 ± 0.554
1.51GlyPhe: 1.51 ± 0.33
7.85GlyGly: 7.85 ± 1.459
2.114GlyHis: 2.114 ± 1.098
4.831GlyIle: 4.831 ± 1.983
2.114GlyLys: 2.114 ± 0.296
9.662GlyLeu: 9.662 ± 0.618
1.51GlyMet: 1.51 ± 0.629
2.114GlyAsn: 2.114 ± 0.685
4.831GlyPro: 4.831 ± 0.474
2.114GlyGln: 2.114 ± 0.525
6.944GlyArg: 6.944 ± 0.628
6.341GlySer: 6.341 ± 1.867
2.717GlyThr: 2.717 ± 0.374
6.944GlyVal: 6.944 ± 1.111
0.906GlyTrp: 0.906 ± 0.53
2.114GlyTyr: 2.114 ± 0.75
0.0GlyXaa: 0.0 ± 0.0
His
3.623HisAla: 3.623 ± 0.36
0.0HisCys: 0.0 ± 0.0
1.51HisAsp: 1.51 ± 0.671
0.906HisGlu: 0.906 ± 0.334
0.604HisPhe: 0.604 ± 0.268
3.019HisGly: 3.019 ± 0.568
0.604HisHis: 0.604 ± 0.335
0.906HisIle: 0.906 ± 0.281
0.302HisLys: 0.302 ± 0.219
3.623HisLeu: 3.623 ± 0.756
1.51HisMet: 1.51 ± 0.515
0.302HisAsn: 0.302 ± 0.256
1.812HisPro: 1.812 ± 0.407
0.604HisGln: 0.604 ± 0.312
1.208HisArg: 1.208 ± 0.412
1.812HisSer: 1.812 ± 0.543
0.906HisThr: 0.906 ± 0.53
2.717HisVal: 2.717 ± 1.217
0.906HisTrp: 0.906 ± 0.517
0.906HisTyr: 0.906 ± 0.418
0.0HisXaa: 0.0 ± 0.0
Ile
4.227IleAla: 4.227 ± 1.391
0.302IleCys: 0.302 ± 0.219
2.415IleAsp: 2.415 ± 0.85
0.302IleGlu: 0.302 ± 0.256
0.0IlePhe: 0.0 ± 0.0
2.114IleGly: 2.114 ± 0.583
0.604IleHis: 0.604 ± 0.294
0.604IleIle: 0.604 ± 0.335
0.906IleLys: 0.906 ± 0.438
2.717IleLeu: 2.717 ± 1.076
1.208IleMet: 1.208 ± 0.501
0.302IleAsn: 0.302 ± 0.295
4.227IlePro: 4.227 ± 0.939
0.906IleGln: 0.906 ± 0.334
2.415IleArg: 2.415 ± 0.19
2.717IleSer: 2.717 ± 0.79
1.51IleThr: 1.51 ± 0.33
2.717IleVal: 2.717 ± 0.723
0.0IleTrp: 0.0 ± 0.0
0.302IleTyr: 0.302 ± 0.295
0.0IleXaa: 0.0 ± 0.0
Lys
3.019LysAla: 3.019 ± 0.863
0.604LysCys: 0.604 ± 0.335
0.604LysAsp: 0.604 ± 0.59
1.208LysGlu: 1.208 ± 0.571
0.906LysPhe: 0.906 ± 0.658
1.812LysGly: 1.812 ± 0.737
1.208LysHis: 1.208 ± 0.377
0.0LysIle: 0.0 ± 0.0
0.604LysLys: 0.604 ± 0.439
3.925LysLeu: 3.925 ± 1.198
0.604LysMet: 0.604 ± 0.268
0.0LysAsn: 0.0 ± 0.0
2.114LysPro: 2.114 ± 0.71
1.51LysGln: 1.51 ± 0.411
1.208LysArg: 1.208 ± 0.412
1.51LysSer: 1.51 ± 0.113
0.302LysThr: 0.302 ± 0.279
0.906LysVal: 0.906 ± 0.273
0.302LysTrp: 0.302 ± 0.219
0.906LysTyr: 0.906 ± 0.388
0.0LysXaa: 0.0 ± 0.0
Leu
10.568LeuAla: 10.568 ± 1.418
2.114LeuCys: 2.114 ± 0.529
6.643LeuAsp: 6.643 ± 1.592
2.415LeuGlu: 2.415 ± 1.065
2.415LeuPhe: 2.415 ± 0.572
10.568LeuGly: 10.568 ± 1.803
3.623LeuHis: 3.623 ± 1.593
2.114LeuIle: 2.114 ± 0.352
1.51LeuLys: 1.51 ± 0.774
9.36LeuLeu: 9.36 ± 1.816
2.717LeuMet: 2.717 ± 0.758
1.812LeuAsn: 1.812 ± 0.543
6.039LeuPro: 6.039 ± 1.241
2.717LeuGln: 2.717 ± 0.789
9.36LeuArg: 9.36 ± 0.27
7.246LeuSer: 7.246 ± 0.685
5.133LeuThr: 5.133 ± 0.651
7.85LeuVal: 7.85 ± 1.558
1.208LeuTrp: 1.208 ± 0.119
2.717LeuTyr: 2.717 ± 0.661
0.0LeuXaa: 0.0 ± 0.0
Met
2.114MetAla: 2.114 ± 0.529
0.302MetCys: 0.302 ± 0.295
1.208MetAsp: 1.208 ± 0.534
0.906MetGlu: 0.906 ± 0.418
0.604MetPhe: 0.604 ± 0.312
1.51MetGly: 1.51 ± 0.667
1.208MetHis: 1.208 ± 0.336
0.302MetIle: 0.302 ± 0.295
0.604MetLys: 0.604 ± 0.266
3.623MetLeu: 3.623 ± 1.369
0.302MetMet: 0.302 ± 0.295
0.302MetAsn: 0.302 ± 0.219
0.906MetPro: 0.906 ± 0.56
0.906MetGln: 0.906 ± 0.517
1.208MetArg: 1.208 ± 0.409
1.812MetSer: 1.812 ± 0.778
2.114MetThr: 2.114 ± 0.296
1.208MetVal: 1.208 ± 0.119
0.604MetTrp: 0.604 ± 0.266
0.906MetTyr: 0.906 ± 0.281
0.0MetXaa: 0.0 ± 0.0
Asn
2.415AsnAla: 2.415 ± 0.869
0.0AsnCys: 0.0 ± 0.0
1.812AsnAsp: 1.812 ± 0.516
0.906AsnGlu: 0.906 ± 0.273
0.906AsnPhe: 0.906 ± 0.273
0.906AsnGly: 0.906 ± 0.56
1.51AsnHis: 1.51 ± 0.641
0.0AsnIle: 0.0 ± 0.0
0.302AsnLys: 0.302 ± 0.219
2.415AsnLeu: 2.415 ± 0.335
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.51AsnPro: 1.51 ± 0.776
0.604AsnGln: 0.604 ± 0.59
2.415AsnArg: 2.415 ± 0.866
3.019AsnSer: 3.019 ± 0.866
0.302AsnThr: 0.302 ± 0.219
1.812AsnVal: 1.812 ± 1.041
0.604AsnTrp: 0.604 ± 0.294
0.604AsnTyr: 0.604 ± 0.268
0.0AsnXaa: 0.0 ± 0.0
Pro
5.435ProAla: 5.435 ± 1.728
0.604ProCys: 0.604 ± 0.294
4.529ProAsp: 4.529 ± 0.37
3.925ProGlu: 3.925 ± 0.414
0.906ProPhe: 0.906 ± 0.56
5.133ProGly: 5.133 ± 0.946
0.302ProHis: 0.302 ± 0.295
0.604ProIle: 0.604 ± 0.312
2.717ProLys: 2.717 ± 0.82
3.925ProLeu: 3.925 ± 0.744
0.604ProMet: 0.604 ± 0.558
1.208ProAsn: 1.208 ± 0.571
2.717ProPro: 2.717 ± 1.232
1.812ProGln: 1.812 ± 0.543
2.717ProArg: 2.717 ± 0.838
3.925ProSer: 3.925 ± 0.162
7.246ProThr: 7.246 ± 1.73
3.019ProVal: 3.019 ± 0.557
0.302ProTrp: 0.302 ± 0.256
1.51ProTyr: 1.51 ± 1.029
0.0ProXaa: 0.0 ± 0.0
Gln
5.435GlnAla: 5.435 ± 0.891
0.604GlnCys: 0.604 ± 0.266
0.604GlnAsp: 0.604 ± 0.266
1.51GlnGlu: 1.51 ± 0.628
0.604GlnPhe: 0.604 ± 0.266
1.812GlnGly: 1.812 ± 0.261
1.208GlnHis: 1.208 ± 0.377
0.604GlnIle: 0.604 ± 0.294
0.906GlnLys: 0.906 ± 0.517
4.529GlnLeu: 4.529 ± 0.338
0.302GlnMet: 0.302 ± 0.295
0.604GlnAsn: 0.604 ± 0.268
2.114GlnPro: 2.114 ± 1.345
2.717GlnGln: 2.717 ± 0.35
2.114GlnArg: 2.114 ± 0.314
2.717GlnSer: 2.717 ± 0.755
1.51GlnThr: 1.51 ± 0.474
2.717GlnVal: 2.717 ± 0.433
0.604GlnTrp: 0.604 ± 0.268
1.208GlnTyr: 1.208 ± 0.409
0.0GlnXaa: 0.0 ± 0.0
Arg
7.246ArgAla: 7.246 ± 1.686
2.415ArgCys: 2.415 ± 0.525
4.529ArgAsp: 4.529 ± 0.996
5.737ArgGlu: 5.737 ± 1.355
2.114ArgPhe: 2.114 ± 0.775
5.133ArgGly: 5.133 ± 1.364
1.208ArgHis: 1.208 ± 0.409
2.717ArgIle: 2.717 ± 0.723
0.906ArgLys: 0.906 ± 0.281
5.133ArgLeu: 5.133 ± 0.651
1.208ArgMet: 1.208 ± 0.531
1.51ArgAsn: 1.51 ± 0.467
3.019ArgPro: 3.019 ± 0.973
2.717ArgGln: 2.717 ± 0.723
5.435ArgArg: 5.435 ± 0.54
6.341ArgSer: 6.341 ± 0.897
4.831ArgThr: 4.831 ± 0.978
7.548ArgVal: 7.548 ± 0.556
0.604ArgTrp: 0.604 ± 0.335
2.415ArgTyr: 2.415 ± 0.622
0.0ArgXaa: 0.0 ± 0.0
Ser
8.454SerAla: 8.454 ± 1.47
0.604SerCys: 0.604 ± 0.268
4.529SerAsp: 4.529 ± 0.697
4.227SerGlu: 4.227 ± 1.415
2.114SerPhe: 2.114 ± 0.296
5.133SerGly: 5.133 ± 0.803
2.415SerHis: 2.415 ± 1.098
2.717SerIle: 2.717 ± 1.314
2.114SerLys: 2.114 ± 0.352
6.341SerLeu: 6.341 ± 0.984
1.812SerMet: 1.812 ± 0.782
1.51SerAsn: 1.51 ± 0.667
3.321SerPro: 3.321 ± 0.383
4.227SerGln: 4.227 ± 1.453
5.737SerArg: 5.737 ± 0.715
5.133SerSer: 5.133 ± 1.777
5.737SerThr: 5.737 ± 1.33
5.737SerVal: 5.737 ± 1.348
1.812SerTrp: 1.812 ± 0.388
0.906SerTyr: 0.906 ± 0.438
0.0SerXaa: 0.0 ± 0.0
Thr
6.039ThrAla: 6.039 ± 0.303
0.604ThrCys: 0.604 ± 0.294
2.114ThrAsp: 2.114 ± 0.929
3.321ThrGlu: 3.321 ± 0.599
0.906ThrPhe: 0.906 ± 0.203
5.737ThrGly: 5.737 ± 0.607
1.208ThrHis: 1.208 ± 0.531
1.208ThrIle: 1.208 ± 0.336
2.415ThrLys: 2.415 ± 0.525
4.227ThrLeu: 4.227 ± 1.304
1.208ThrMet: 1.208 ± 0.119
0.906ThrAsn: 0.906 ± 0.53
4.529ThrPro: 4.529 ± 1.202
1.208ThrGln: 1.208 ± 0.336
3.925ThrArg: 3.925 ± 0.62
5.133ThrSer: 5.133 ± 1.299
6.039ThrThr: 6.039 ± 1.433
6.643ThrVal: 6.643 ± 1.13
1.51ThrTrp: 1.51 ± 0.515
1.208ThrTyr: 1.208 ± 0.536
0.0ThrXaa: 0.0 ± 0.0
Val
6.944ValAla: 6.944 ± 1.338
0.906ValCys: 0.906 ± 0.768
4.831ValAsp: 4.831 ± 1.017
4.227ValGlu: 4.227 ± 1.404
3.321ValPhe: 3.321 ± 1.057
6.341ValGly: 6.341 ± 0.646
3.019ValHis: 3.019 ± 0.595
1.51ValIle: 1.51 ± 0.817
1.51ValLys: 1.51 ± 0.474
11.775ValLeu: 11.775 ± 1.58
1.208ValMet: 1.208 ± 0.286
2.717ValAsn: 2.717 ± 1.082
2.114ValPro: 2.114 ± 0.745
1.812ValGln: 1.812 ± 0.672
9.058ValArg: 9.058 ± 1.27
6.944ValSer: 6.944 ± 1.445
3.623ValThr: 3.623 ± 0.586
6.643ValVal: 6.643 ± 1.128
0.906ValTrp: 0.906 ± 0.273
4.831ValTyr: 4.831 ± 0.996
0.0ValXaa: 0.0 ± 0.0
Trp
1.812TrpAla: 1.812 ± 0.562
0.0TrpCys: 0.0 ± 0.0
0.302TrpAsp: 0.302 ± 0.279
0.604TrpGlu: 0.604 ± 0.294
0.604TrpPhe: 0.604 ± 0.268
0.906TrpGly: 0.906 ± 0.539
0.302TrpHis: 0.302 ± 0.295
0.0TrpIle: 0.0 ± 0.0
0.302TrpLys: 0.302 ± 0.279
2.114TrpLeu: 2.114 ± 0.213
0.604TrpMet: 0.604 ± 0.512
0.302TrpAsn: 0.302 ± 0.295
0.906TrpPro: 0.906 ± 0.334
0.906TrpGln: 0.906 ± 0.517
1.208TrpArg: 1.208 ± 0.611
1.51TrpSer: 1.51 ± 0.774
0.604TrpThr: 0.604 ± 0.268
2.717TrpVal: 2.717 ± 0.503
0.0TrpTrp: 0.0 ± 0.0
0.302TrpTyr: 0.302 ± 0.219
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.321TyrAla: 3.321 ± 0.608
0.604TyrCys: 0.604 ± 0.268
2.114TyrAsp: 2.114 ± 0.352
0.906TyrGlu: 0.906 ± 0.418
1.208TyrPhe: 1.208 ± 0.877
3.321TyrGly: 3.321 ± 0.568
0.302TyrHis: 0.302 ± 0.219
0.906TyrIle: 0.906 ± 0.273
0.0TyrLys: 0.0 ± 0.0
3.019TyrLeu: 3.019 ± 0.687
0.906TyrMet: 0.906 ± 0.616
0.302TyrAsn: 0.302 ± 0.256
0.906TyrPro: 0.906 ± 0.334
0.906TyrGln: 0.906 ± 0.281
2.114TyrArg: 2.114 ± 0.314
2.717TyrSer: 2.717 ± 0.933
0.906TyrThr: 0.906 ± 0.438
3.925TyrVal: 3.925 ± 0.518
0.302TyrTrp: 0.302 ± 0.219
1.51TyrTyr: 1.51 ± 0.454
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3313 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski