Amino acid dipepetide frequency for Nylanderia fulva

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.971AlaAla: 2.971 ± 0.162
1.492AlaCys: 1.492 ± 0.081
1.145AlaAsp: 1.145 ± 0.084
1.781AlaGlu: 1.781 ± 0.108
3.022AlaPhe: 3.022 ± 0.119
3.807AlaGly: 3.807 ± 0.119
1.055AlaHis: 1.055 ± 0.085
6.154AlaIle: 6.154 ± 0.199
2.386AlaLys: 2.386 ± 0.128
5.563AlaLeu: 5.563 ± 0.178
2.785AlaMet: 2.785 ± 0.128
2.296AlaAsn: 2.296 ± 0.129
0.707AlaPro: 0.707 ± 0.06
1.659AlaGln: 1.659 ± 0.106
2.231AlaArg: 2.231 ± 0.111
3.73AlaSer: 3.73 ± 0.162
3.286AlaThr: 3.286 ± 0.138
3.994AlaVal: 3.994 ± 0.16
0.688AlaTrp: 0.688 ± 0.06
2.958AlaTyr: 2.958 ± 0.125
0.0AlaXaa: 0.0 ± 0.0
Cys
1.569CysAla: 1.569 ± 0.1
0.939CysCys: 0.939 ± 0.071
0.881CysAsp: 0.881 ± 0.078
0.617CysGlu: 0.617 ± 0.061
2.058CysPhe: 2.058 ± 0.098
2.598CysGly: 2.598 ± 0.128
0.379CysHis: 0.379 ± 0.047
2.534CysIle: 2.534 ± 0.116
1.203CysLys: 1.203 ± 0.09
3.376CysLeu: 3.376 ± 0.133
0.823CysMet: 0.823 ± 0.068
0.926CysAsn: 0.926 ± 0.076
0.334CysPro: 0.334 ± 0.049
0.598CysGln: 0.598 ± 0.067
0.682CysArg: 0.682 ± 0.07
1.852CysSer: 1.852 ± 0.092
1.511CysThr: 1.511 ± 0.091
1.601CysVal: 1.601 ± 0.111
0.65CysTrp: 0.65 ± 0.071
1.17CysTyr: 1.17 ± 0.104
0.0CysXaa: 0.0 ± 0.0
Asp
1.73AspAla: 1.73 ± 0.099
0.817AspCys: 0.817 ± 0.069
1.666AspAsp: 1.666 ± 0.1
1.511AspGlu: 1.511 ± 0.075
1.563AspPhe: 1.563 ± 0.099
0.9AspGly: 0.9 ± 0.087
0.894AspHis: 0.894 ± 0.074
3.833AspIle: 3.833 ± 0.126
1.801AspLys: 1.801 ± 0.108
3.093AspLeu: 3.093 ± 0.145
0.958AspMet: 0.958 ± 0.08
2.096AspAsn: 2.096 ± 0.115
0.399AspPro: 0.399 ± 0.051
0.92AspGln: 0.92 ± 0.075
1.46AspArg: 1.46 ± 0.09
1.865AspSer: 1.865 ± 0.099
1.801AspThr: 1.801 ± 0.093
1.897AspVal: 1.897 ± 0.101
1.833AspTrp: 1.833 ± 0.078
0.868AspTyr: 0.868 ± 0.075
0.0AspXaa: 0.0 ± 0.0
Glu
1.466GluAla: 1.466 ± 0.089
0.836GluCys: 0.836 ± 0.069
2.051GluAsp: 2.051 ± 0.125
1.614GluGlu: 1.614 ± 0.104
1.678GluPhe: 1.678 ± 0.096
0.913GluGly: 0.913 ± 0.077
1.119GluHis: 1.119 ± 0.077
4.09GluIle: 4.09 ± 0.166
2.778GluLys: 2.778 ± 0.143
3.305GluLeu: 3.305 ± 0.138
1.17GluMet: 1.17 ± 0.088
2.868GluAsn: 2.868 ± 0.106
0.637GluPro: 0.637 ± 0.063
1.331GluGln: 1.331 ± 0.087
1.936GluArg: 1.936 ± 0.095
2.804GluSer: 2.804 ± 0.139
2.096GluThr: 2.096 ± 0.107
1.813GluVal: 1.813 ± 0.099
0.894GluTrp: 0.894 ± 0.077
2.309GluTyr: 2.309 ± 0.104
0.0GluXaa: 0.0 ± 0.0
Phe
4.328PheAla: 4.328 ± 0.131
2.649PheCys: 2.649 ± 0.112
1.511PheAsp: 1.511 ± 0.097
2.225PheGlu: 2.225 ± 0.108
3.865PhePhe: 3.865 ± 0.179
2.669PheGly: 2.669 ± 0.132
1.408PheHis: 1.408 ± 0.102
7.794PheIle: 7.794 ± 0.242
2.276PheLys: 2.276 ± 0.117
7.865PheLeu: 7.865 ± 0.236
2.412PheMet: 2.412 ± 0.116
2.894PheAsn: 2.894 ± 0.111
1.267PhePro: 1.267 ± 0.092
2.283PheGln: 2.283 ± 0.13
2.251PheArg: 2.251 ± 0.11
5.157PheSer: 5.157 ± 0.167
5.112PheThr: 5.112 ± 0.183
5.485PheVal: 5.485 ± 0.167
0.759PheTrp: 0.759 ± 0.067
3.048PheTyr: 3.048 ± 0.141
0.0PheXaa: 0.0 ± 0.0
Gly
1.473GlyAla: 1.473 ± 0.102
0.926GlyCys: 0.926 ± 0.067
1.344GlyAsp: 1.344 ± 0.086
1.473GlyGlu: 1.473 ± 0.101
2.399GlyPhe: 2.399 ± 0.11
1.486GlyGly: 1.486 ± 0.089
0.502GlyHis: 0.502 ± 0.06
3.903GlyIle: 3.903 ± 0.159
2.347GlyLys: 2.347 ± 0.106
4.643GlyLeu: 4.643 ± 0.16
1.325GlyMet: 1.325 ± 0.095
1.826GlyAsn: 1.826 ± 0.095
0.559GlyPro: 0.559 ± 0.048
2.437GlyGln: 2.437 ± 0.1
1.113GlyArg: 1.113 ± 0.086
1.858GlySer: 1.858 ± 0.105
1.428GlyThr: 1.428 ± 0.094
2.367GlyVal: 2.367 ± 0.12
0.148GlyTrp: 0.148 ± 0.029
1.698GlyTyr: 1.698 ± 0.096
0.0GlyXaa: 0.0 ± 0.0
His
1.588HisAla: 1.588 ± 0.094
0.405HisCys: 0.405 ± 0.055
0.592HisAsp: 0.592 ± 0.057
0.572HisGlu: 0.572 ± 0.061
1.08HisPhe: 1.08 ± 0.1
0.502HisGly: 0.502 ± 0.055
0.643HisHis: 0.643 ± 0.058
2.424HisIle: 2.424 ± 0.111
0.675HisLys: 0.675 ± 0.063
2.701HisLeu: 2.701 ± 0.116
0.804HisMet: 0.804 ± 0.07
0.797HisAsn: 0.797 ± 0.065
0.315HisPro: 0.315 ± 0.042
1.151HisGln: 1.151 ± 0.078
1.164HisArg: 1.164 ± 0.09
1.389HisSer: 1.389 ± 0.08
1.087HisThr: 1.087 ± 0.082
1.704HisVal: 1.704 ± 0.107
0.264HisTrp: 0.264 ± 0.047
1.01HisTyr: 1.01 ± 0.073
0.0HisXaa: 0.0 ± 0.0
Ile
6.334IleAla: 6.334 ± 0.19
3.942IleCys: 3.942 ± 0.154
3.042IleAsp: 3.042 ± 0.129
5.061IleGlu: 5.061 ± 0.177
8.399IlePhe: 8.399 ± 0.233
4.83IleGly: 4.83 ± 0.196
2.129IleHis: 2.129 ± 0.112
12.077IleIle: 12.077 ± 0.347
4.154IleLys: 4.154 ± 0.164
14.617IleLeu: 14.617 ± 0.287
5.325IleMet: 5.325 ± 0.2
4.296IleAsn: 4.296 ± 0.189
2.746IlePro: 2.746 ± 0.133
3.203IleGln: 3.203 ± 0.129
4.116IleArg: 4.116 ± 0.178
6.637IleSer: 6.637 ± 0.208
7.022IleThr: 7.022 ± 0.205
7.222IleVal: 7.222 ± 0.223
1.035IleTrp: 1.035 ± 0.08
4.9IleTyr: 4.9 ± 0.181
0.0IleXaa: 0.0 ± 0.0
Lys
2.482LysAla: 2.482 ± 0.113
0.804LysCys: 0.804 ± 0.07
2.276LysAsp: 2.276 ± 0.109
1.813LysGlu: 1.813 ± 0.095
2.675LysPhe: 2.675 ± 0.14
0.727LysGly: 0.727 ± 0.065
1.318LysHis: 1.318 ± 0.086
5.659LysIle: 5.659 ± 0.21
2.27LysLys: 2.27 ± 0.128
5.293LysLeu: 5.293 ± 0.147
1.949LysMet: 1.949 ± 0.101
2.572LysAsn: 2.572 ± 0.134
1.46LysPro: 1.46 ± 0.082
1.473LysGln: 1.473 ± 0.094
1.749LysArg: 1.749 ± 0.091
3.846LysSer: 3.846 ± 0.148
3.453LysThr: 3.453 ± 0.131
2.373LysVal: 2.373 ± 0.113
0.476LysTrp: 0.476 ± 0.05
2.72LysTyr: 2.72 ± 0.157
0.0LysXaa: 0.0 ± 0.0
Leu
5.833LeuAla: 5.833 ± 0.169
2.598LeuCys: 2.598 ± 0.117
2.572LeuAsp: 2.572 ± 0.124
4.669LeuGlu: 4.669 ± 0.138
8.199LeuPhe: 8.199 ± 0.243
3.531LeuGly: 3.531 ± 0.148
3.138LeuHis: 3.138 ± 0.13
14.726LeuIle: 14.726 ± 0.27
5.717LeuLys: 5.717 ± 0.163
16.083LeuLeu: 16.083 ± 0.339
4.952LeuMet: 4.952 ± 0.165
4.958LeuAsn: 4.958 ± 0.17
4.103LeuPro: 4.103 ± 0.143
4.81LeuGln: 4.81 ± 0.143
4.887LeuArg: 4.887 ± 0.149
10.315LeuSer: 10.315 ± 0.223
9.119LeuThr: 9.119 ± 0.238
7.646LeuVal: 7.646 ± 0.208
1.691LeuTrp: 1.691 ± 0.094
4.264LeuTyr: 4.264 ± 0.178
0.0LeuXaa: 0.0 ± 0.0
Met
2.09MetAla: 2.09 ± 0.107
0.92MetCys: 0.92 ± 0.084
1.582MetAsp: 1.582 ± 0.097
1.974MetGlu: 1.974 ± 0.126
2.675MetPhe: 2.675 ± 0.124
0.952MetGly: 0.952 ± 0.079
0.842MetHis: 0.842 ± 0.075
4.733MetIle: 4.733 ± 0.169
2.322MetLys: 2.322 ± 0.134
5.061MetLeu: 5.061 ± 0.156
1.794MetMet: 1.794 ± 0.11
1.646MetAsn: 1.646 ± 0.095
0.926MetPro: 0.926 ± 0.074
1.621MetGln: 1.621 ± 0.098
1.717MetArg: 1.717 ± 0.103
3.17MetSer: 3.17 ± 0.131
2.688MetThr: 2.688 ± 0.112
2.219MetVal: 2.219 ± 0.111
0.315MetTrp: 0.315 ± 0.039
1.691MetTyr: 1.691 ± 0.092
0.0MetXaa: 0.0 ± 0.0
Asn
2.579AsnAla: 2.579 ± 0.134
0.714AsnCys: 0.714 ± 0.074
1.949AsnAsp: 1.949 ± 0.126
2.399AsnGlu: 2.399 ± 0.114
2.778AsnPhe: 2.778 ± 0.116
0.932AsnGly: 0.932 ± 0.084
0.752AsnHis: 0.752 ± 0.07
5.511AsnIle: 5.511 ± 0.198
2.527AsnLys: 2.527 ± 0.13
6.129AsnLeu: 6.129 ± 0.205
2.186AsnMet: 2.186 ± 0.122
2.367AsnAsn: 2.367 ± 0.116
0.418AsnPro: 0.418 ± 0.054
1.183AsnGln: 1.183 ± 0.079
2.013AsnArg: 2.013 ± 0.092
2.566AsnSer: 2.566 ± 0.134
2.752AsnThr: 2.752 ± 0.135
3.37AsnVal: 3.37 ± 0.146
0.662AsnTrp: 0.662 ± 0.066
1.904AsnTyr: 1.904 ± 0.11
0.0AsnXaa: 0.0 ± 0.0
Pro
0.868ProAla: 0.868 ± 0.068
0.862ProCys: 0.862 ± 0.069
0.733ProAsp: 0.733 ± 0.06
0.476ProGlu: 0.476 ± 0.053
2.244ProPhe: 2.244 ± 0.115
0.823ProGly: 0.823 ± 0.074
0.354ProHis: 0.354 ± 0.042
2.193ProIle: 2.193 ± 0.113
0.92ProLys: 0.92 ± 0.075
4.116ProLeu: 4.116 ± 0.125
0.977ProMet: 0.977 ± 0.085
0.797ProAsn: 0.797 ± 0.077
0.444ProPro: 0.444 ± 0.073
0.772ProGln: 0.772 ± 0.064
0.804ProArg: 0.804 ± 0.073
1.395ProSer: 1.395 ± 0.095
0.997ProThr: 0.997 ± 0.088
1.473ProVal: 1.473 ± 0.105
0.264ProTrp: 0.264 ± 0.037
1.788ProTyr: 1.788 ± 0.089
0.0ProXaa: 0.0 ± 0.0
Gln
1.408GlnAla: 1.408 ± 0.09
0.932GlnCys: 0.932 ± 0.075
0.746GlnAsp: 0.746 ± 0.069
1.203GlnGlu: 1.203 ± 0.093
2.81GlnPhe: 2.81 ± 0.126
0.65GlnGly: 0.65 ± 0.07
0.971GlnHis: 0.971 ± 0.075
3.659GlnIle: 3.659 ± 0.139
2.862GlnLys: 2.862 ± 0.137
4.913GlnLeu: 4.913 ± 0.167
1.37GlnMet: 1.37 ± 0.087
1.17GlnAsn: 1.17 ± 0.097
0.611GlnPro: 0.611 ± 0.072
1.074GlnGln: 1.074 ± 0.072
1.801GlnArg: 1.801 ± 0.102
2.084GlnSer: 2.084 ± 0.096
2.109GlnThr: 2.109 ± 0.122
1.704GlnVal: 1.704 ± 0.109
0.341GlnTrp: 0.341 ± 0.046
1.415GlnTyr: 1.415 ± 0.103
0.0GlnXaa: 0.0 ± 0.0
Arg
2.109ArgAla: 2.109 ± 0.116
0.836ArgCys: 0.836 ± 0.065
1.37ArgAsp: 1.37 ± 0.08
1.633ArgGlu: 1.633 ± 0.092
2.135ArgPhe: 2.135 ± 0.085
0.598ArgGly: 0.598 ± 0.069
1.28ArgHis: 1.28 ± 0.091
4.727ArgIle: 4.727 ± 0.171
2.566ArgLys: 2.566 ± 0.131
4.579ArgLeu: 4.579 ± 0.154
1.068ArgMet: 1.068 ± 0.079
2.141ArgAsn: 2.141 ± 0.118
1.151ArgPro: 1.151 ± 0.072
1.183ArgGln: 1.183 ± 0.073
2.309ArgArg: 2.309 ± 0.12
3.035ArgSer: 3.035 ± 0.13
2.212ArgThr: 2.212 ± 0.106
2.154ArgVal: 2.154 ± 0.111
0.733ArgTrp: 0.733 ± 0.075
1.865ArgTyr: 1.865 ± 0.1
0.0ArgXaa: 0.0 ± 0.0
Ser
3.807SerAla: 3.807 ± 0.123
1.621SerCys: 1.621 ± 0.091
1.878SerAsp: 1.878 ± 0.107
2.109SerGlu: 2.109 ± 0.12
5.08SerPhe: 5.08 ± 0.195
2.071SerGly: 2.071 ± 0.108
0.997SerHis: 0.997 ± 0.086
7.402SerIle: 7.402 ± 0.228
3.177SerLys: 3.177 ± 0.124
9.653SerLeu: 9.653 ± 0.256
3.19SerMet: 3.19 ± 0.141
3.235SerAsn: 3.235 ± 0.149
1.653SerPro: 1.653 ± 0.088
2.424SerGln: 2.424 ± 0.115
2.894SerArg: 2.894 ± 0.132
5.106SerSer: 5.106 ± 0.197
4.489SerThr: 4.489 ± 0.177
5.537SerVal: 5.537 ± 0.186
0.682SerTrp: 0.682 ± 0.06
4.392SerTyr: 4.392 ± 0.124
0.0SerXaa: 0.0 ± 0.0
Thr
3.994ThrAla: 3.994 ± 0.154
1.395ThrCys: 1.395 ± 0.092
2.617ThrAsp: 2.617 ± 0.131
2.322ThrGlu: 2.322 ± 0.114
5.485ThrPhe: 5.485 ± 0.183
1.884ThrGly: 1.884 ± 0.129
0.997ThrHis: 0.997 ± 0.079
6.952ThrIle: 6.952 ± 0.195
2.296ThrLys: 2.296 ± 0.124
8.257ThrLeu: 8.257 ± 0.241
2.907ThrMet: 2.907 ± 0.121
2.733ThrAsn: 2.733 ± 0.118
1.035ThrPro: 1.035 ± 0.076
1.723ThrGln: 1.723 ± 0.101
1.981ThrArg: 1.981 ± 0.11
5.228ThrSer: 5.228 ± 0.172
3.569ThrThr: 3.569 ± 0.173
4.437ThrVal: 4.437 ± 0.14
0.463ThrTrp: 0.463 ± 0.052
2.791ThrTyr: 2.791 ± 0.103
0.0ThrXaa: 0.0 ± 0.0
Val
3.254ValAla: 3.254 ± 0.143
1.884ValCys: 1.884 ± 0.103
2.148ValAsp: 2.148 ± 0.112
2.347ValGlu: 2.347 ± 0.106
4.334ValPhe: 4.334 ± 0.145
3.209ValGly: 3.209 ± 0.172
1.305ValHis: 1.305 ± 0.093
6.804ValIle: 6.804 ± 0.193
2.585ValLys: 2.585 ± 0.112
8.791ValLeu: 8.791 ± 0.227
3.093ValMet: 3.093 ± 0.132
2.566ValAsn: 2.566 ± 0.133
1.55ValPro: 1.55 ± 0.097
2.039ValGln: 2.039 ± 0.093
1.685ValArg: 1.685 ± 0.096
4.739ValSer: 4.739 ± 0.179
4.534ValThr: 4.534 ± 0.182
3.801ValVal: 3.801 ± 0.147
0.9ValTrp: 0.9 ± 0.072
3.022ValTyr: 3.022 ± 0.132
0.0ValXaa: 0.0 ± 0.0
Trp
0.527TrpAla: 0.527 ± 0.043
0.161TrpCys: 0.161 ± 0.034
0.109TrpAsp: 0.109 ± 0.027
0.309TrpGlu: 0.309 ± 0.045
0.566TrpPhe: 0.566 ± 0.057
0.476TrpGly: 0.476 ± 0.059
0.129TrpHis: 0.129 ± 0.03
0.92TrpIle: 0.92 ± 0.076
0.797TrpLys: 0.797 ± 0.066
1.235TrpLeu: 1.235 ± 0.087
0.129TrpMet: 0.129 ± 0.028
0.643TrpAsn: 0.643 ± 0.068
2.302TrpPro: 2.302 ± 0.068
0.482TrpGln: 0.482 ± 0.054
0.502TrpArg: 0.502 ± 0.048
0.521TrpSer: 0.521 ± 0.058
0.617TrpThr: 0.617 ± 0.066
0.257TrpVal: 0.257 ± 0.046
0.161TrpTrp: 0.161 ± 0.033
2.392TrpTyr: 2.392 ± 0.062
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.299TyrAla: 3.299 ± 0.142
1.569TyrCys: 1.569 ± 0.088
1.691TyrAsp: 1.691 ± 0.089
1.601TyrGlu: 1.601 ± 0.109
4.212TyrPhe: 4.212 ± 0.177
1.698TyrGly: 1.698 ± 0.094
0.656TyrHis: 0.656 ± 0.063
4.99TyrIle: 4.99 ± 0.183
1.736TyrLys: 1.736 ± 0.116
4.54TyrLeu: 4.54 ± 0.136
1.717TyrMet: 1.717 ± 0.095
2.862TyrAsn: 2.862 ± 0.124
0.682TyrPro: 0.682 ± 0.064
1.466TyrGln: 1.466 ± 0.09
2.392TyrArg: 2.392 ± 0.112
4.096TyrSer: 4.096 ± 0.145
3.183TyrThr: 3.183 ± 0.157
3.537TyrVal: 3.537 ± 0.154
0.277TyrTrp: 0.277 ± 0.048
2.772TyrTyr: 2.772 ± 0.131
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 426 proteins (155503 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski