Amino acid dipepetide frequency for Gordonia aichiensis NBRC 108223

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.833AlaAla: 17.833 ± 0.146	0.938AlaCys: 0.938 ± 0.028	9.107AlaAsp: 9.107 ± 0.091	7.139AlaGlu: 7.139 ± 0.082	3.357AlaPhe: 3.357 ± 0.049	10.819AlaGly: 10.819 ± 0.09	2.758AlaHis: 2.758 ± 0.043	5.608AlaIle: 5.608 ± 0.065	2.701AlaLys: 2.701 ± 0.057	12.16AlaLeu: 12.16 ± 0.101	2.728AlaMet: 2.728 ± 0.042	2.354AlaAsn: 2.354 ± 0.04	5.869AlaPro: 5.869 ± 0.073	4.003AlaGln: 4.003 ± 0.055	8.608AlaArg: 8.608 ± 0.082	6.853AlaSer: 6.853 ± 0.072	7.67AlaThr: 7.67 ± 0.078	10.886AlaVal: 10.886 ± 0.098	1.511AlaTrp: 1.511 ± 0.032	2.308AlaTyr: 2.308 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.025CysAla: 1.025 ± 0.027	0.105CysCys: 0.105 ± 0.009	0.48CysAsp: 0.48 ± 0.02	0.366CysGlu: 0.366 ± 0.017	0.224CysPhe: 0.224 ± 0.011	0.922CysGly: 0.922 ± 0.023	0.183CysHis: 0.183 ± 0.012	0.279CysIle: 0.279 ± 0.014	0.099CysLys: 0.099 ± 0.008	0.588CysLeu: 0.588 ± 0.019	0.127CysMet: 0.127 ± 0.01	0.153CysAsn: 0.153 ± 0.011	0.432CysPro: 0.432 ± 0.021	0.153CysGln: 0.153 ± 0.01	0.566CysArg: 0.566 ± 0.022	0.495CysSer: 0.495 ± 0.018	0.484CysThr: 0.484 ± 0.017	0.69CysVal: 0.69 ± 0.021	0.111CysTrp: 0.111 ± 0.009	0.172CysTyr: 0.172 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.796AspAla: 8.796 ± 0.096	0.387AspCys: 0.387 ± 0.017	5.733AspAsp: 5.733 ± 0.075	4.629AspGlu: 4.629 ± 0.059	1.842AspPhe: 1.842 ± 0.042	6.108AspGly: 6.108 ± 0.073	1.662AspHis: 1.662 ± 0.037	2.837AspIle: 2.837 ± 0.049	1.45AspLys: 1.45 ± 0.035	6.439AspLeu: 6.439 ± 0.077	1.068AspMet: 1.068 ± 0.026	1.394AspAsn: 1.394 ± 0.031	4.388AspPro: 4.388 ± 0.041	1.75AspGln: 1.75 ± 0.037	4.82AspArg: 4.82 ± 0.06	3.561AspSer: 3.561 ± 0.057	3.737AspThr: 3.737 ± 0.048	6.049AspVal: 6.049 ± 0.069	0.896AspTrp: 0.896 ± 0.026	1.416AspTyr: 1.416 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	5.478GluAla: 5.478 ± 0.077	0.374GluCys: 0.374 ± 0.016	2.143GluAsp: 2.143 ± 0.044	2.352GluGlu: 2.352 ± 0.055	1.867GluPhe: 1.867 ± 0.038	3.263GluGly: 3.263 ± 0.051	1.545GluHis: 1.545 ± 0.031	2.93GluIle: 2.93 ± 0.045	1.496GluLys: 1.496 ± 0.039	6.302GluLeu: 6.302 ± 0.068	1.09GluMet: 1.09 ± 0.028	1.312GluAsn: 1.312 ± 0.031	2.856GluPro: 2.856 ± 0.043	2.163GluGln: 2.163 ± 0.041	4.398GluArg: 4.398 ± 0.061	3.249GluSer: 3.249 ± 0.046	2.76GluThr: 2.76 ± 0.043	4.454GluVal: 4.454 ± 0.06	0.867GluTrp: 0.867 ± 0.026	1.182GluTyr: 1.182 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.933PheAla: 3.933 ± 0.063	0.289PheCys: 0.289 ± 0.013	2.624PheAsp: 2.624 ± 0.046	1.421PheGlu: 1.421 ± 0.036	1.014PhePhe: 1.014 ± 0.026	3.356PheGly: 3.356 ± 0.055	0.608PheHis: 0.608 ± 0.022	1.141PheIle: 1.141 ± 0.03	0.437PheLys: 0.437 ± 0.019	2.484PheLeu: 2.484 ± 0.046	0.495PheMet: 0.495 ± 0.017	0.674PheAsn: 0.674 ± 0.022	1.345PhePro: 1.345 ± 0.028	0.577PheGln: 0.577 ± 0.019	1.753PheArg: 1.753 ± 0.032	1.79PheSer: 1.79 ± 0.035	2.104PheThr: 2.104 ± 0.037	2.679PheVal: 2.679 ± 0.05	0.436PheTrp: 0.436 ± 0.016	0.689PheTyr: 0.689 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	9.798GlyAla: 9.798 ± 0.094	0.757GlyCys: 0.757 ± 0.025	5.36GlyAsp: 5.36 ± 0.063	4.401GlyGlu: 4.401 ± 0.059	3.018GlyPhe: 3.018 ± 0.049	7.374GlyGly: 7.374 ± 0.104	1.985GlyHis: 1.985 ± 0.038	4.247GlyIle: 4.247 ± 0.058	2.353GlyLys: 2.353 ± 0.044	8.092GlyLeu: 8.092 ± 0.081	1.981GlyMet: 1.981 ± 0.037	1.892GlyAsn: 1.892 ± 0.04	4.167GlyPro: 4.167 ± 0.062	2.62GlyGln: 2.62 ± 0.052	6.211GlyArg: 6.211 ± 0.066	5.716GlySer: 5.716 ± 0.059	5.442GlyThr: 5.442 ± 0.065	7.94GlyVal: 7.94 ± 0.076	1.509GlyTrp: 1.509 ± 0.036	2.352GlyTyr: 2.352 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.431HisAla: 2.431 ± 0.041	0.195HisCys: 0.195 ± 0.011	1.517HisAsp: 1.517 ± 0.031	1.097HisGlu: 1.097 ± 0.026	0.64HisPhe: 0.64 ± 0.022	2.003HisGly: 2.003 ± 0.036	0.722HisHis: 0.722 ± 0.023	0.894HisIle: 0.894 ± 0.023	0.377HisLys: 0.377 ± 0.016	2.124HisLeu: 2.124 ± 0.036	0.404HisMet: 0.404 ± 0.017	0.465HisAsn: 0.465 ± 0.018	1.577HisPro: 1.577 ± 0.034	0.601HisGln: 0.601 ± 0.021	1.944HisArg: 1.944 ± 0.04	1.259HisSer: 1.259 ± 0.029	1.302HisThr: 1.302 ± 0.031	1.754HisVal: 1.754 ± 0.037	0.342HisTrp: 0.342 ± 0.016	0.525HisTyr: 0.525 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.765IleAla: 6.765 ± 0.073	0.409IleCys: 0.409 ± 0.017	3.922IleAsp: 3.922 ± 0.054	2.713IleGlu: 2.713 ± 0.043	1.11IlePhe: 1.11 ± 0.03	4.669IleGly: 4.669 ± 0.059	0.827IleHis: 0.827 ± 0.02	1.773IleIle: 1.773 ± 0.048	0.87IleLys: 0.87 ± 0.026	3.396IleLeu: 3.396 ± 0.046	0.606IleMet: 0.606 ± 0.021	1.102IleAsn: 1.102 ± 0.029	2.448IlePro: 2.448 ± 0.043	0.812IleGln: 0.812 ± 0.029	2.877IleArg: 2.877 ± 0.041	2.659IleSer: 2.659 ± 0.041	3.019IleThr: 3.019 ± 0.052	4.336IleVal: 4.336 ± 0.06	0.475IleTrp: 0.475 ± 0.02	0.829IleTyr: 0.829 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.492LysAla: 2.492 ± 0.051	0.115LysCys: 0.115 ± 0.008	1.088LysAsp: 1.088 ± 0.03	0.937LysGlu: 0.937 ± 0.032	0.574LysPhe: 0.574 ± 0.018	1.63LysGly: 1.63 ± 0.036	0.445LysHis: 0.445 ± 0.02	1.091LysIle: 1.091 ± 0.028	0.793LysLys: 0.793 ± 0.035	2.029LysLeu: 2.029 ± 0.041	0.458LysMet: 0.458 ± 0.021	0.602LysAsn: 0.602 ± 0.022	1.342LysPro: 1.342 ± 0.034	0.767LysGln: 0.767 ± 0.027	1.597LysArg: 1.597 ± 0.035	1.329LysSer: 1.329 ± 0.034	1.418LysThr: 1.418 ± 0.037	1.962LysVal: 1.962 ± 0.04	0.283LysTrp: 0.283 ± 0.014	0.481LysTyr: 0.481 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	12.923LeuAla: 12.923 ± 0.104	0.779LeuCys: 0.779 ± 0.023	7.08LeuAsp: 7.08 ± 0.093	4.145LeuGlu: 4.145 ± 0.065	2.67LeuPhe: 2.67 ± 0.045	8.517LeuGly: 8.517 ± 0.078	1.969LeuHis: 1.969 ± 0.035	4.331LeuIle: 4.331 ± 0.056	1.643LeuLys: 1.643 ± 0.04	8.696LeuLeu: 8.696 ± 0.094	1.688LeuMet: 1.688 ± 0.036	1.851LeuAsn: 1.851 ± 0.036	5.209LeuPro: 5.209 ± 0.062	2.055LeuGln: 2.055 ± 0.038	7.24LeuArg: 7.24 ± 0.086	5.742LeuSer: 5.742 ± 0.073	6.248LeuThr: 6.248 ± 0.06	8.36LeuVal: 8.36 ± 0.089	1.128LeuTrp: 1.128 ± 0.025	1.629LeuTyr: 1.629 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.339MetAla: 2.339 ± 0.039	0.173MetCys: 0.173 ± 0.012	0.81MetAsp: 0.81 ± 0.023	0.665MetGlu: 0.665 ± 0.025	0.612MetPhe: 0.612 ± 0.023	1.423MetGly: 1.423 ± 0.03	0.429MetHis: 0.429 ± 0.014	0.967MetIle: 0.967 ± 0.027	0.427MetLys: 0.427 ± 0.017	1.99MetLeu: 1.99 ± 0.032	0.41MetMet: 0.41 ± 0.016	0.523MetAsn: 0.523 ± 0.021	1.162MetPro: 1.162 ± 0.03	0.502MetGln: 0.502 ± 0.017	1.535MetArg: 1.535 ± 0.032	1.848MetSer: 1.848 ± 0.033	1.862MetThr: 1.862 ± 0.035	1.64MetVal: 1.64 ± 0.036	0.249MetTrp: 0.249 ± 0.011	0.351MetTyr: 0.351 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.607AsnAla: 2.607 ± 0.043	0.161AsnCys: 0.161 ± 0.01	1.307AsnAsp: 1.307 ± 0.034	0.965AsnGlu: 0.965 ± 0.025	0.605AsnPhe: 0.605 ± 0.021	2.14AsnGly: 2.14 ± 0.042	0.452AsnHis: 0.452 ± 0.016	0.951AsnIle: 0.951 ± 0.025	0.532AsnLys: 0.532 ± 0.021	1.931AsnLeu: 1.931 ± 0.039	0.402AsnMet: 0.402 ± 0.015	0.573AsnAsn: 0.573 ± 0.021	1.714AsnPro: 1.714 ± 0.035	0.605AsnGln: 0.605 ± 0.021	1.543AsnArg: 1.543 ± 0.033	1.278AsnSer: 1.278 ± 0.028	1.377AsnThr: 1.377 ± 0.028	1.693AsnVal: 1.693 ± 0.035	0.333AsnTrp: 0.333 ± 0.015	0.534AsnTyr: 0.534 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.445ProAla: 6.445 ± 0.079	0.273ProCys: 0.273 ± 0.016	4.666ProAsp: 4.666 ± 0.061	3.428ProGlu: 3.428 ± 0.048	1.557ProPhe: 1.557 ± 0.029	5.125ProGly: 5.125 ± 0.064	1.193ProHis: 1.193 ± 0.031	2.259ProIle: 2.259 ± 0.041	1.212ProLys: 1.212 ± 0.033	4.514ProLeu: 4.514 ± 0.053	1.073ProMet: 1.073 ± 0.028	1.171ProAsn: 1.171 ± 0.031	2.689ProPro: 2.689 ± 0.057	1.633ProGln: 1.633 ± 0.041	3.541ProArg: 3.541 ± 0.054	3.385ProSer: 3.385 ± 0.054	3.773ProThr: 3.773 ± 0.052	4.624ProVal: 4.624 ± 0.062	0.777ProTrp: 0.777 ± 0.026	1.071ProTyr: 1.071 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.129GlnAla: 3.129 ± 0.044	0.206GlnCys: 0.206 ± 0.011	0.972GlnAsp: 0.972 ± 0.026	1.052GlnGlu: 1.052 ± 0.025	0.878GlnPhe: 0.878 ± 0.022	1.905GlnGly: 1.905 ± 0.04	0.64GlnHis: 0.64 ± 0.023	1.57GlnIle: 1.57 ± 0.033	0.665GlnLys: 0.665 ± 0.027	3.05GlnLeu: 3.05 ± 0.05	0.647GlnMet: 0.647 ± 0.021	0.644GlnAsn: 0.644 ± 0.018	1.636GlnPro: 1.636 ± 0.037	1.24GlnGln: 1.24 ± 0.03	2.571GlnArg: 2.571 ± 0.05	1.644GlnSer: 1.644 ± 0.034	1.608GlnThr: 1.608 ± 0.033	2.386GlnVal: 2.386 ± 0.04	0.517GlnTrp: 0.517 ± 0.019	0.622GlnTyr: 0.622 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.293ArgAla: 8.293 ± 0.079	0.517ArgCys: 0.517 ± 0.018	4.685ArgAsp: 4.685 ± 0.055	4.161ArgGlu: 4.161 ± 0.06	2.378ArgPhe: 2.378 ± 0.039	5.285ArgGly: 5.285 ± 0.064	1.749ArgHis: 1.749 ± 0.035	3.526ArgIle: 3.526 ± 0.051	1.614ArgLys: 1.614 ± 0.035	6.953ArgLeu: 6.953 ± 0.085	1.793ArgMet: 1.793 ± 0.031	1.626ArgAsn: 1.626 ± 0.03	3.755ArgPro: 3.755 ± 0.05	2.057ArgGln: 2.057 ± 0.043	6.95ArgArg: 6.95 ± 0.087	4.56ArgSer: 4.56 ± 0.059	4.522ArgThr: 4.522 ± 0.063	5.781ArgVal: 5.781 ± 0.062	1.266ArgTrp: 1.266 ± 0.036	1.803ArgTyr: 1.803 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.752SerAla: 7.752 ± 0.084	0.394SerCys: 0.394 ± 0.017	4.228SerAsp: 4.228 ± 0.057	2.99SerGlu: 2.99 ± 0.05	1.689SerPhe: 1.689 ± 0.039	6.326SerGly: 6.326 ± 0.072	1.152SerHis: 1.152 ± 0.029	2.587SerIle: 2.587 ± 0.047	1.242SerLys: 1.242 ± 0.03	5.124SerLeu: 5.124 ± 0.054	1.481SerMet: 1.481 ± 0.032	1.248SerAsn: 1.248 ± 0.032	3.291SerPro: 3.291 ± 0.045	1.522SerGln: 1.522 ± 0.034	4.039SerArg: 4.039 ± 0.051	4.165SerSer: 4.165 ± 0.065	4.441SerThr: 4.441 ± 0.06	5.272SerVal: 5.272 ± 0.062	0.912SerTrp: 0.912 ± 0.027	1.229SerTyr: 1.229 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	7.902ThrAla: 7.902 ± 0.077	0.447ThrCys: 0.447 ± 0.019	4.357ThrAsp: 4.357 ± 0.054	3.305ThrGlu: 3.305 ± 0.048	1.881ThrPhe: 1.881 ± 0.036	5.801ThrGly: 5.801 ± 0.064	1.354ThrHis: 1.354 ± 0.028	2.904ThrIle: 2.904 ± 0.043	1.273ThrLys: 1.273 ± 0.035	5.664ThrLeu: 5.664 ± 0.061	1.195ThrMet: 1.195 ± 0.031	1.289ThrAsn: 1.289 ± 0.027	4.188ThrPro: 4.188 ± 0.061	1.592ThrGln: 1.592 ± 0.037	4.113ThrArg: 4.113 ± 0.062	4.1ThrSer: 4.1 ± 0.047	4.716ThrThr: 4.716 ± 0.074	5.943ThrVal: 5.943 ± 0.059	0.904ThrTrp: 0.904 ± 0.026	1.356ThrTyr: 1.356 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	11.474ValAla: 11.474 ± 0.103	0.773ValCys: 0.773 ± 0.022	6.838ValAsp: 6.838 ± 0.077	4.68ValGlu: 4.68 ± 0.062	2.659ValPhe: 2.659 ± 0.051	7.535ValGly: 7.535 ± 0.075	1.754ValHis: 1.754 ± 0.033	4.325ValIle: 4.325 ± 0.054	1.517ValLys: 1.517 ± 0.04	8.525ValLeu: 8.525 ± 0.073	1.632ValMet: 1.632 ± 0.037	1.946ValAsn: 1.946 ± 0.042	4.457ValPro: 4.457 ± 0.062	1.753ValGln: 1.753 ± 0.032	5.897ValArg: 5.897 ± 0.066	5.244ValSer: 5.244 ± 0.066	5.686ValThr: 5.686 ± 0.055	9.222ValVal: 9.222 ± 0.098	1.055ValTrp: 1.055 ± 0.028	1.53ValTyr: 1.53 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.477TrpAla: 1.477 ± 0.03	0.161TrpCys: 0.161 ± 0.011	0.703TrpAsp: 0.703 ± 0.02	0.599TrpGlu: 0.599 ± 0.02	0.547TrpPhe: 0.547 ± 0.02	0.989TrpGly: 0.989 ± 0.028	0.336TrpHis: 0.336 ± 0.014	0.71TrpIle: 0.71 ± 0.021	0.355TrpLys: 0.355 ± 0.016	1.591TrpLeu: 1.591 ± 0.038	0.345TrpMet: 0.345 ± 0.017	0.423TrpAsn: 0.423 ± 0.018	0.709TrpPro: 0.709 ± 0.021	0.55TrpGln: 0.55 ± 0.02	1.205TrpArg: 1.205 ± 0.028	0.927TrpSer: 0.927 ± 0.027	0.877TrpThr: 0.877 ± 0.024	1.124TrpVal: 1.124 ± 0.03	0.342TrpTrp: 0.342 ± 0.016	0.313TrpTyr: 0.313 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.319TyrAla: 2.319 ± 0.039	0.202TyrCys: 0.202 ± 0.012	1.343TyrAsp: 1.343 ± 0.032	1.037TyrGlu: 1.037 ± 0.026	0.727TyrPhe: 0.727 ± 0.021	2.026TyrGly: 2.026 ± 0.042	0.408TyrHis: 0.408 ± 0.018	0.686TyrIle: 0.686 ± 0.024	0.38TyrLys: 0.38 ± 0.017	2.254TyrLeu: 2.254 ± 0.037	0.293TyrMet: 0.293 ± 0.016	0.461TyrAsn: 0.461 ± 0.019	1.175TyrPro: 1.175 ± 0.028	0.625TyrGln: 0.625 ± 0.02	1.866TyrArg: 1.866 ± 0.038	1.279TyrSer: 1.279 ± 0.028	1.237TyrThr: 1.237 ± 0.03	1.704TyrVal: 1.704 ± 0.038	0.371TyrTrp: 0.371 ± 0.015	0.473TyrTyr: 0.473 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4613 proteins (1538364 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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