Amino acid dipepetide frequency for Moniliophthora roreri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.761AlaAla: 6.761 ± 0.045
0.959AlaCys: 0.959 ± 0.013
3.597AlaAsp: 3.597 ± 0.023
4.472AlaGlu: 4.472 ± 0.029
3.199AlaPhe: 3.199 ± 0.022
4.741AlaGly: 4.741 ± 0.029
1.724AlaHis: 1.724 ± 0.013
4.15AlaIle: 4.15 ± 0.027
3.696AlaLys: 3.696 ± 0.022
7.582AlaLeu: 7.582 ± 0.035
1.782AlaMet: 1.782 ± 0.015
2.746AlaAsn: 2.746 ± 0.019
4.216AlaPro: 4.216 ± 0.033
3.022AlaGln: 3.022 ± 0.02
4.198AlaArg: 4.198 ± 0.026
6.874AlaSer: 6.874 ± 0.037
4.674AlaThr: 4.674 ± 0.027
4.769AlaVal: 4.769 ± 0.027
1.051AlaTrp: 1.051 ± 0.014
1.994AlaTyr: 1.994 ± 0.019
0.0AlaXaa: 0.0 ± 0.0
Cys
0.881CysAla: 0.881 ± 0.011
0.232CysCys: 0.232 ± 0.007
0.635CysAsp: 0.635 ± 0.009
0.59CysGlu: 0.59 ± 0.009
0.551CysPhe: 0.551 ± 0.009
0.82CysGly: 0.82 ± 0.011
0.354CysHis: 0.354 ± 0.007
0.739CysIle: 0.739 ± 0.011
0.571CysLys: 0.571 ± 0.009
1.281CysLeu: 1.281 ± 0.013
0.258CysMet: 0.258 ± 0.006
0.46CysAsn: 0.46 ± 0.01
0.706CysPro: 0.706 ± 0.011
0.496CysGln: 0.496 ± 0.008
0.712CysArg: 0.712 ± 0.009
0.998CysSer: 0.998 ± 0.012
0.754CysThr: 0.754 ± 0.012
0.792CysVal: 0.792 ± 0.012
0.206CysTrp: 0.206 ± 0.006
0.371CysTyr: 0.371 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
4.209AspAla: 4.209 ± 0.025
0.634AspCys: 0.634 ± 0.009
4.138AspAsp: 4.138 ± 0.032
4.337AspGlu: 4.337 ± 0.035
2.198AspPhe: 2.198 ± 0.019
3.754AspGly: 3.754 ± 0.025
1.292AspHis: 1.292 ± 0.014
3.343AspIle: 3.343 ± 0.025
2.349AspLys: 2.349 ± 0.018
4.996AspLeu: 4.996 ± 0.032
1.238AspMet: 1.238 ± 0.013
1.92AspAsn: 1.92 ± 0.016
3.416AspPro: 3.416 ± 0.022
1.714AspGln: 1.714 ± 0.014
2.771AspArg: 2.771 ± 0.02
4.275AspSer: 4.275 ± 0.026
3.138AspThr: 3.138 ± 0.021
3.724AspVal: 3.724 ± 0.022
0.982AspTrp: 0.982 ± 0.011
1.533AspTyr: 1.533 ± 0.013
0.0AspXaa: 0.0 ± 0.0
Glu
4.734GluAla: 4.734 ± 0.03
0.668GluCys: 0.668 ± 0.009
4.125GluAsp: 4.125 ± 0.03
5.572GluGlu: 5.572 ± 0.044
2.04GluPhe: 2.04 ± 0.017
3.706GluGly: 3.706 ± 0.026
1.444GluHis: 1.444 ± 0.013
3.016GluIle: 3.016 ± 0.02
3.584GluLys: 3.584 ± 0.025
5.293GluLeu: 5.293 ± 0.032
1.443GluMet: 1.443 ± 0.013
2.178GluAsn: 2.178 ± 0.017
2.688GluPro: 2.688 ± 0.021
2.323GluGln: 2.323 ± 0.022
3.859GluArg: 3.859 ± 0.029
4.192GluSer: 4.192 ± 0.024
3.14GluThr: 3.14 ± 0.02
3.749GluVal: 3.749 ± 0.026
1.059GluTrp: 1.059 ± 0.012
1.755GluTyr: 1.755 ± 0.015
0.0GluXaa: 0.0 ± 0.0
Phe
2.887PheAla: 2.887 ± 0.021
0.578PheCys: 0.578 ± 0.009
2.376PheAsp: 2.376 ± 0.019
2.149PheGlu: 2.149 ± 0.016
1.815PhePhe: 1.815 ± 0.016
2.766PheGly: 2.766 ± 0.026
1.028PheHis: 1.028 ± 0.012
2.213PheIle: 2.213 ± 0.018
1.69PheLys: 1.69 ± 0.016
3.863PheLeu: 3.863 ± 0.025
0.872PheMet: 0.872 ± 0.01
1.619PheAsn: 1.619 ± 0.016
2.12PhePro: 2.12 ± 0.018
1.452PheGln: 1.452 ± 0.014
2.028PheArg: 2.028 ± 0.015
3.281PheSer: 3.281 ± 0.021
2.435PheThr: 2.435 ± 0.019
2.539PheVal: 2.539 ± 0.019
0.672PheTrp: 0.672 ± 0.01
1.118PheTyr: 1.118 ± 0.012
0.0PheXaa: 0.0 ± 0.0
Gly
4.365GlyAla: 4.365 ± 0.028
0.805GlyCys: 0.805 ± 0.011
3.264GlyAsp: 3.264 ± 0.022
3.302GlyGlu: 3.302 ± 0.023
2.589GlyPhe: 2.589 ± 0.02
5.011GlyGly: 5.011 ± 0.041
1.569GlyHis: 1.569 ± 0.016
3.437GlyIle: 3.437 ± 0.023
3.345GlyLys: 3.345 ± 0.022
5.665GlyLeu: 5.665 ± 0.027
1.461GlyMet: 1.461 ± 0.016
2.45GlyAsn: 2.45 ± 0.022
3.082GlyPro: 3.082 ± 0.024
2.258GlyGln: 2.258 ± 0.02
3.538GlyArg: 3.538 ± 0.023
5.5GlySer: 5.5 ± 0.029
3.824GlyThr: 3.824 ± 0.024
4.104GlyVal: 4.104 ± 0.03
1.095GlyTrp: 1.095 ± 0.013
2.075GlyTyr: 2.075 ± 0.018
0.0GlyXaa: 0.0 ± 0.0
His
1.751HisAla: 1.751 ± 0.014
0.33HisCys: 0.33 ± 0.006
1.297HisAsp: 1.297 ± 0.015
1.276HisGlu: 1.276 ± 0.012
1.01HisPhe: 1.01 ± 0.014
1.549HisGly: 1.549 ± 0.015
0.877HisHis: 0.877 ± 0.014
1.432HisIle: 1.432 ± 0.014
0.938HisLys: 0.938 ± 0.012
2.521HisLeu: 2.521 ± 0.02
0.479HisMet: 0.479 ± 0.009
0.942HisAsn: 0.942 ± 0.012
1.969HisPro: 1.969 ± 0.018
0.971HisGln: 0.971 ± 0.011
1.541HisArg: 1.541 ± 0.018
2.182HisSer: 2.182 ± 0.019
1.443HisThr: 1.443 ± 0.015
1.558HisVal: 1.558 ± 0.014
0.355HisTrp: 0.355 ± 0.008
0.745HisTyr: 0.745 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.033IleAla: 4.033 ± 0.024
0.76IleCys: 0.76 ± 0.01
2.947IleAsp: 2.947 ± 0.02
2.882IleGlu: 2.882 ± 0.019
2.175IlePhe: 2.175 ± 0.018
3.13IleGly: 3.13 ± 0.022
1.44IleHis: 1.44 ± 0.015
2.868IleIle: 2.868 ± 0.022
2.329IleLys: 2.329 ± 0.019
5.062IleLeu: 5.062 ± 0.029
1.056IleMet: 1.056 ± 0.013
1.913IleAsn: 1.913 ± 0.017
3.625IlePro: 3.625 ± 0.021
2.034IleGln: 2.034 ± 0.017
2.968IleArg: 2.968 ± 0.019
4.375IleSer: 4.375 ± 0.026
3.172IleThr: 3.172 ± 0.022
3.409IleVal: 3.409 ± 0.024
0.788IleTrp: 0.788 ± 0.011
1.546IleTyr: 1.546 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
4.025LysAla: 4.025 ± 0.026
0.58LysCys: 0.58 ± 0.01
2.859LysAsp: 2.859 ± 0.021
3.709LysGlu: 3.709 ± 0.027
1.561LysPhe: 1.561 ± 0.015
3.119LysGly: 3.119 ± 0.027
1.158LysHis: 1.158 ± 0.011
2.28LysIle: 2.28 ± 0.019
3.479LysLys: 3.479 ± 0.033
4.306LysLeu: 4.306 ± 0.028
1.014LysMet: 1.014 ± 0.013
1.778LysAsn: 1.778 ± 0.016
2.738LysPro: 2.738 ± 0.021
1.808LysGln: 1.808 ± 0.016
3.302LysArg: 3.302 ± 0.024
3.478LysSer: 3.478 ± 0.024
2.661LysThr: 2.661 ± 0.022
2.848LysVal: 2.848 ± 0.022
0.764LysTrp: 0.764 ± 0.009
1.327LysTyr: 1.327 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
7.167LeuAla: 7.167 ± 0.032
1.304LeuCys: 1.304 ± 0.012
5.233LeuAsp: 5.233 ± 0.03
5.616LeuGlu: 5.616 ± 0.029
3.728LeuPhe: 3.728 ± 0.023
5.426LeuGly: 5.426 ± 0.029
2.513LeuHis: 2.513 ± 0.018
4.351LeuIle: 4.351 ± 0.023
4.572LeuLys: 4.572 ± 0.03
8.932LeuLeu: 8.932 ± 0.047
1.833LeuMet: 1.833 ± 0.017
3.472LeuAsn: 3.472 ± 0.022
6.243LeuPro: 6.243 ± 0.029
3.784LeuGln: 3.784 ± 0.022
5.642LeuArg: 5.642 ± 0.033
8.248LeuSer: 8.248 ± 0.039
5.227LeuThr: 5.227 ± 0.029
5.622LeuVal: 5.622 ± 0.032
1.311LeuTrp: 1.311 ± 0.015
2.588LeuTyr: 2.588 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
1.83MetAla: 1.83 ± 0.015
0.231MetCys: 0.231 ± 0.006
1.32MetAsp: 1.32 ± 0.014
1.311MetGlu: 1.311 ± 0.014
0.85MetPhe: 0.85 ± 0.009
1.311MetGly: 1.311 ± 0.016
0.511MetHis: 0.511 ± 0.008
1.047MetIle: 1.047 ± 0.011
1.142MetLys: 1.142 ± 0.012
1.903MetLeu: 1.903 ± 0.017
0.563MetMet: 0.563 ± 0.01
0.933MetAsn: 0.933 ± 0.012
1.282MetPro: 1.282 ± 0.012
0.804MetGln: 0.804 ± 0.009
1.092MetArg: 1.092 ± 0.013
2.062MetSer: 2.062 ± 0.017
1.356MetThr: 1.356 ± 0.012
1.279MetVal: 1.279 ± 0.013
0.268MetTrp: 0.268 ± 0.005
0.547MetTyr: 0.547 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.138AsnAla: 3.138 ± 0.022
0.443AsnCys: 0.443 ± 0.007
2.141AsnAsp: 2.141 ± 0.019
2.06AsnGlu: 2.06 ± 0.018
1.419AsnPhe: 1.419 ± 0.014
2.728AsnGly: 2.728 ± 0.023
0.927AsnHis: 0.927 ± 0.012
2.182AsnIle: 2.182 ± 0.019
1.504AsnLys: 1.504 ± 0.015
3.45AsnLeu: 3.45 ± 0.023
0.798AsnMet: 0.798 ± 0.011
1.631AsnAsn: 1.631 ± 0.022
2.589AsnPro: 2.589 ± 0.022
1.416AsnGln: 1.416 ± 0.015
1.936AsnArg: 1.936 ± 0.016
3.044AsnSer: 3.044 ± 0.02
2.456AsnThr: 2.456 ± 0.021
2.578AsnVal: 2.578 ± 0.018
0.561AsnTrp: 0.561 ± 0.009
1.032AsnTyr: 1.032 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
4.527ProAla: 4.527 ± 0.03
0.577ProCys: 0.577 ± 0.008
3.254ProAsp: 3.254 ± 0.02
3.823ProGlu: 3.823 ± 0.022
2.414ProPhe: 2.414 ± 0.021
3.566ProGly: 3.566 ± 0.025
1.489ProHis: 1.489 ± 0.016
2.985ProIle: 2.985 ± 0.022
2.772ProLys: 2.772 ± 0.022
5.196ProLeu: 5.196 ± 0.03
1.115ProMet: 1.115 ± 0.015
2.479ProAsn: 2.479 ± 0.018
5.969ProPro: 5.969 ± 0.057
2.459ProGln: 2.459 ± 0.021
3.265ProArg: 3.265 ± 0.024
6.914ProSer: 6.914 ± 0.043
4.44ProThr: 4.44 ± 0.028
3.694ProVal: 3.694 ± 0.025
0.729ProTrp: 0.729 ± 0.011
1.591ProTyr: 1.591 ± 0.014
0.0ProXaa: 0.0 ± 0.0
Gln
3.083GlnAla: 3.083 ± 0.023
0.501GlnCys: 0.501 ± 0.008
1.957GlnAsp: 1.957 ± 0.016
2.276GlnGlu: 2.276 ± 0.016
1.383GlnPhe: 1.383 ± 0.014
2.112GlnGly: 2.112 ± 0.018
1.037GlnHis: 1.037 ± 0.012
1.955GlnIle: 1.955 ± 0.018
1.877GlnLys: 1.877 ± 0.017
3.45GlnLeu: 3.45 ± 0.024
0.891GlnMet: 0.891 ± 0.013
1.505GlnAsn: 1.505 ± 0.016
2.345GlnPro: 2.345 ± 0.022
2.015GlnGln: 2.015 ± 0.031
2.385GlnArg: 2.385 ± 0.019
3.1GlnSer: 3.1 ± 0.025
2.357GlnThr: 2.357 ± 0.018
2.256GlnVal: 2.256 ± 0.017
0.628GlnTrp: 0.628 ± 0.01
1.145GlnTyr: 1.145 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
4.127ArgAla: 4.127 ± 0.024
0.736ArgCys: 0.736 ± 0.01
3.06ArgAsp: 3.06 ± 0.02
3.581ArgGlu: 3.581 ± 0.029
2.273ArgPhe: 2.273 ± 0.018
3.246ArgGly: 3.246 ± 0.024
1.483ArgHis: 1.483 ± 0.015
3.051ArgIle: 3.051 ± 0.02
3.318ArgLys: 3.318 ± 0.024
5.281ArgLeu: 5.281 ± 0.031
1.307ArgMet: 1.307 ± 0.013
2.248ArgAsn: 2.248 ± 0.019
3.306ArgPro: 3.306 ± 0.025
2.207ArgGln: 2.207 ± 0.02
4.569ArgArg: 4.569 ± 0.034
4.808ArgSer: 4.808 ± 0.032
3.282ArgThr: 3.282 ± 0.025
3.339ArgVal: 3.339 ± 0.021
0.949ArgTrp: 0.949 ± 0.012
1.622ArgTyr: 1.622 ± 0.016
0.0ArgXaa: 0.0 ± 0.0
Ser
6.315SerAla: 6.315 ± 0.031
0.919SerCys: 0.919 ± 0.014
4.508SerAsp: 4.508 ± 0.024
4.3SerGlu: 4.3 ± 0.024
3.464SerPhe: 3.464 ± 0.021
5.515SerGly: 5.515 ± 0.031
2.13SerHis: 2.13 ± 0.019
4.323SerIle: 4.323 ± 0.024
3.676SerLys: 3.676 ± 0.027
8.049SerLeu: 8.049 ± 0.039
1.821SerMet: 1.821 ± 0.015
3.284SerAsn: 3.284 ± 0.024
6.197SerPro: 6.197 ± 0.043
3.363SerGln: 3.363 ± 0.023
5.007SerArg: 5.007 ± 0.029
10.371SerSer: 10.371 ± 0.076
6.243SerThr: 6.243 ± 0.037
4.982SerVal: 4.982 ± 0.027
1.186SerTrp: 1.186 ± 0.014
2.139SerTyr: 2.139 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
4.585ThrAla: 4.585 ± 0.03
0.736ThrCys: 0.736 ± 0.01
2.834ThrAsp: 2.834 ± 0.02
3.05ThrGlu: 3.05 ± 0.021
2.5ThrPhe: 2.5 ± 0.017
3.794ThrGly: 3.794 ± 0.026
1.44ThrHis: 1.44 ± 0.013
3.453ThrIle: 3.453 ± 0.02
2.633ThrLys: 2.633 ± 0.02
5.836ThrLeu: 5.836 ± 0.029
1.267ThrMet: 1.267 ± 0.013
2.225ThrAsn: 2.225 ± 0.017
4.637ThrPro: 4.637 ± 0.032
2.127ThrGln: 2.127 ± 0.016
3.236ThrArg: 3.236 ± 0.023
6.044ThrSer: 6.044 ± 0.04
4.414ThrThr: 4.414 ± 0.031
3.934ThrVal: 3.934 ± 0.023
0.85ThrTrp: 0.85 ± 0.011
1.665ThrTyr: 1.665 ± 0.015
0.0ThrXaa: 0.0 ± 0.0
Val
4.76ValAla: 4.76 ± 0.028
0.792ValCys: 0.792 ± 0.012
3.694ValAsp: 3.694 ± 0.027
3.879ValGlu: 3.879 ± 0.027
2.567ValPhe: 2.567 ± 0.019
3.69ValGly: 3.69 ± 0.025
1.549ValHis: 1.549 ± 0.016
3.356ValIle: 3.356 ± 0.024
3.093ValLys: 3.093 ± 0.022
5.968ValLeu: 5.968 ± 0.032
1.39ValMet: 1.39 ± 0.013
2.365ValAsn: 2.365 ± 0.02
3.811ValPro: 3.811 ± 0.027
2.398ValGln: 2.398 ± 0.018
3.127ValArg: 3.127 ± 0.02
4.736ValSer: 4.736 ± 0.025
3.644ValThr: 3.644 ± 0.023
4.46ValVal: 4.46 ± 0.031
0.921ValTrp: 0.921 ± 0.011
1.916ValTyr: 1.916 ± 0.015
0.0ValXaa: 0.0 ± 0.0
Trp
1.047TrpAla: 1.047 ± 0.013
0.228TrpCys: 0.228 ± 0.005
0.94TrpAsp: 0.94 ± 0.012
0.91TrpGlu: 0.91 ± 0.011
0.587TrpPhe: 0.587 ± 0.008
0.892TrpGly: 0.892 ± 0.013
0.358TrpHis: 0.358 ± 0.007
0.84TrpIle: 0.84 ± 0.011
1.024TrpLys: 1.024 ± 0.012
1.382TrpLeu: 1.382 ± 0.016
0.399TrpMet: 0.399 ± 0.008
0.704TrpAsn: 0.704 ± 0.01
0.618TrpPro: 0.618 ± 0.01
0.536TrpGln: 0.536 ± 0.008
0.987TrpArg: 0.987 ± 0.011
1.161TrpSer: 1.161 ± 0.013
0.908TrpThr: 0.908 ± 0.011
0.848TrpVal: 0.848 ± 0.01
0.314TrpTrp: 0.314 ± 0.006
0.447TrpTyr: 0.447 ± 0.008
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.984TyrAla: 1.984 ± 0.018
0.396TyrCys: 0.396 ± 0.008
1.781TyrAsp: 1.781 ± 0.016
1.471TyrGlu: 1.471 ± 0.013
1.175TyrPhe: 1.175 ± 0.013
1.865TyrGly: 1.865 ± 0.018
0.841TyrHis: 0.841 ± 0.011
1.491TyrIle: 1.491 ± 0.015
1.205TyrLys: 1.205 ± 0.014
2.796TyrLeu: 2.796 ± 0.023
0.653TyrMet: 0.653 ± 0.011
1.183TyrAsn: 1.183 ± 0.014
1.701TyrPro: 1.701 ± 0.018
1.071TyrGln: 1.071 ± 0.012
1.629TyrArg: 1.629 ± 0.015
2.15TyrSer: 2.15 ± 0.02
1.691TyrThr: 1.691 ± 0.016
1.631TyrVal: 1.631 ± 0.016
0.441TyrTrp: 0.441 ± 0.006
0.899TyrTyr: 0.899 ± 0.011
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 19789 proteins (7744644 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski