Amino acid dipepetide frequency for Rice yellow mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.984AlaAla: 5.984 ± 1.885
3.324AlaCys: 3.324 ± 1.973
5.319AlaAsp: 5.319 ± 2.194
5.984AlaGlu: 5.984 ± 1.317
0.665AlaPhe: 0.665 ± 0.462
6.649AlaGly: 6.649 ± 0.926
1.995AlaHis: 1.995 ± 0.573
4.654AlaIle: 4.654 ± 0.933
1.995AlaLys: 1.995 ± 1.069
4.654AlaLeu: 4.654 ± 1.243
0.665AlaMet: 0.665 ± 0.491
1.995AlaAsn: 1.995 ± 0.711
3.324AlaPro: 3.324 ± 0.765
3.324AlaGln: 3.324 ± 0.466
5.319AlaArg: 5.319 ± 2.737
9.309AlaSer: 9.309 ± 1.341
1.995AlaThr: 1.995 ± 1.294
5.984AlaVal: 5.984 ± 1.408
0.665AlaTrp: 0.665 ± 0.462
1.33AlaTyr: 1.33 ± 0.923
0.0AlaXaa: 0.0 ± 0.0
Cys
1.995CysAla: 1.995 ± 0.573
0.0CysCys: 0.0 ± 0.0
1.995CysAsp: 1.995 ± 0.573
1.33CysGlu: 1.33 ± 0.73
1.995CysPhe: 1.995 ± 1.139
0.665CysGly: 0.665 ± 0.491
0.665CysHis: 0.665 ± 0.745
0.665CysIle: 0.665 ± 0.491
1.33CysLys: 1.33 ± 0.981
1.995CysLeu: 1.995 ± 1.472
0.0CysMet: 0.0 ± 0.0
0.665CysAsn: 0.665 ± 0.733
1.33CysPro: 1.33 ± 0.4
0.665CysGln: 0.665 ± 0.462
0.665CysArg: 0.665 ± 0.733
2.66CysSer: 2.66 ± 0.439
1.995CysThr: 1.995 ± 1.378
1.995CysVal: 1.995 ± 0.806
0.0CysTrp: 0.0 ± 0.0
0.665CysTyr: 0.665 ± 0.745
0.0CysXaa: 0.0 ± 0.0
Asp
4.654AspAla: 4.654 ± 1.325
2.66AspCys: 2.66 ± 1.53
3.324AspAsp: 3.324 ± 1.084
3.324AspGlu: 3.324 ± 1.228
3.989AspPhe: 3.989 ± 0.795
3.324AspGly: 3.324 ± 1.121
1.33AspHis: 1.33 ± 0.923
3.324AspIle: 3.324 ± 1.084
0.665AspLys: 0.665 ± 0.733
3.989AspLeu: 3.989 ± 1.534
0.0AspMet: 0.0 ± 0.0
0.665AspAsn: 0.665 ± 0.462
4.654AspPro: 4.654 ± 2.021
0.665AspGln: 0.665 ± 0.491
1.33AspArg: 1.33 ± 0.792
3.324AspSer: 3.324 ± 1.057
2.66AspThr: 2.66 ± 2.018
4.654AspVal: 4.654 ± 1.325
1.33AspTrp: 1.33 ± 0.981
0.665AspTyr: 0.665 ± 0.745
0.0AspXaa: 0.0 ± 0.0
Glu
1.995GluAla: 1.995 ± 0.711
1.33GluCys: 1.33 ± 0.923
2.66GluAsp: 2.66 ± 0.8
1.995GluGlu: 1.995 ± 0.711
1.33GluPhe: 1.33 ± 0.828
5.984GluGly: 5.984 ± 1.538
1.995GluHis: 1.995 ± 1.378
3.324GluIle: 3.324 ± 1.293
1.33GluLys: 1.33 ± 0.73
5.319GluLeu: 5.319 ± 3.925
0.665GluMet: 0.665 ± 0.745
2.66GluAsn: 2.66 ± 1.13
2.66GluPro: 2.66 ± 0.439
1.995GluGln: 1.995 ± 0.573
9.309GluArg: 9.309 ± 2.077
3.324GluSer: 3.324 ± 2.309
2.66GluThr: 2.66 ± 1.13
5.319GluVal: 5.319 ± 0.289
0.665GluTrp: 0.665 ± 0.491
1.995GluTyr: 1.995 ± 0.711
0.0GluXaa: 0.0 ± 0.0
Phe
0.665PheAla: 0.665 ± 0.733
0.665PheCys: 0.665 ± 0.491
3.324PheAsp: 3.324 ± 1.084
1.995PheGlu: 1.995 ± 0.711
0.0PhePhe: 0.0 ± 0.0
3.324PheGly: 3.324 ± 1.121
0.665PheHis: 0.665 ± 0.462
0.0PheIle: 0.0 ± 0.0
1.33PheLys: 1.33 ± 0.624
3.324PheLeu: 3.324 ± 0.995
1.995PheMet: 1.995 ± 0.944
2.66PheAsn: 2.66 ± 1.212
0.665PhePro: 0.665 ± 0.491
1.995PheGln: 1.995 ± 1.472
1.995PheArg: 1.995 ± 0.767
3.324PheSer: 3.324 ± 1.574
0.665PheThr: 0.665 ± 0.462
3.324PheVal: 3.324 ± 0.602
0.0PheTrp: 0.0 ± 0.0
0.665PheTyr: 0.665 ± 0.462
0.0PheXaa: 0.0 ± 0.0
Gly
3.989GlyAla: 3.989 ± 0.85
1.33GlyCys: 1.33 ± 0.624
3.324GlyAsp: 3.324 ± 1.574
3.324GlyGlu: 3.324 ± 1.121
1.995GlyPhe: 1.995 ± 1.139
3.324GlyGly: 3.324 ± 0.765
2.66GlyHis: 2.66 ± 0.8
2.66GlyIle: 2.66 ± 1.13
5.984GlyLys: 5.984 ± 2.138
8.644GlyLeu: 8.644 ± 2.67
0.665GlyMet: 0.665 ± 0.491
1.33GlyAsn: 1.33 ± 0.981
1.995GlyPro: 1.995 ± 1.139
2.66GlyGln: 2.66 ± 0.738
5.319GlyArg: 5.319 ± 1.05
9.973GlySer: 9.973 ± 1.537
4.654GlyThr: 4.654 ± 1.153
4.654GlyVal: 4.654 ± 1.432
3.324GlyTrp: 3.324 ± 0.769
1.995GlyTyr: 1.995 ± 1.069
0.0GlyXaa: 0.0 ± 0.0
His
2.66HisAla: 2.66 ± 0.715
0.0HisCys: 0.0 ± 0.0
1.33HisAsp: 1.33 ± 0.792
1.33HisGlu: 1.33 ± 0.4
0.0HisPhe: 0.0 ± 0.0
0.665HisGly: 0.665 ± 0.462
0.665HisHis: 0.665 ± 0.462
1.995HisIle: 1.995 ± 1.385
1.33HisLys: 1.33 ± 0.4
2.66HisLeu: 2.66 ± 0.439
0.0HisMet: 0.0 ± 0.0
0.665HisAsn: 0.665 ± 0.491
2.66HisPro: 2.66 ± 0.8
1.33HisGln: 1.33 ± 0.4
0.0HisArg: 0.0 ± 0.0
2.66HisSer: 2.66 ± 1.595
1.995HisThr: 1.995 ± 0.767
1.33HisVal: 1.33 ± 0.923
0.0HisTrp: 0.0 ± 0.0
1.33HisTyr: 1.33 ± 1.467
0.0HisXaa: 0.0 ± 0.0
Ile
5.984IleAla: 5.984 ± 2.0
0.0IleCys: 0.0 ± 0.0
1.33IleAsp: 1.33 ± 0.792
3.324IleGlu: 3.324 ± 0.466
1.995IlePhe: 1.995 ± 1.472
2.66IleGly: 2.66 ± 0.8
0.0IleHis: 0.0 ± 0.0
0.665IleIle: 0.665 ± 0.462
0.665IleLys: 0.665 ± 0.745
3.324IleLeu: 3.324 ± 0.466
0.0IleMet: 0.0 ± 0.0
0.665IleAsn: 0.665 ± 0.491
5.319IlePro: 5.319 ± 2.065
0.665IleGln: 0.665 ± 0.491
4.654IleArg: 4.654 ± 1.289
4.654IleSer: 4.654 ± 2.336
0.0IleThr: 0.0 ± 0.0
3.324IleVal: 3.324 ± 2.309
1.33IleTrp: 1.33 ± 0.4
0.665IleTyr: 0.665 ± 0.462
0.0IleXaa: 0.0 ± 0.0
Lys
1.995LysAla: 1.995 ± 1.004
0.0LysCys: 0.0 ± 0.0
1.995LysAsp: 1.995 ± 0.767
3.324LysGlu: 3.324 ± 1.057
0.665LysPhe: 0.665 ± 0.462
3.989LysGly: 3.989 ± 1.002
1.33LysHis: 1.33 ± 0.981
0.665LysIle: 0.665 ± 0.462
2.66LysLys: 2.66 ± 1.156
1.995LysLeu: 1.995 ± 0.475
1.33LysMet: 1.33 ± 0.651
0.665LysAsn: 0.665 ± 0.491
3.989LysPro: 3.989 ± 1.002
1.995LysGln: 1.995 ± 1.385
3.324LysArg: 3.324 ± 1.89
4.654LysSer: 4.654 ± 1.432
1.995LysThr: 1.995 ± 0.475
3.324LysVal: 3.324 ± 1.095
0.0LysTrp: 0.0 ± 0.0
1.995LysTyr: 1.995 ± 1.378
0.0LysXaa: 0.0 ± 0.0
Leu
7.979LeuAla: 7.979 ± 2.99
1.33LeuCys: 1.33 ± 0.981
2.66LeuAsp: 2.66 ± 1.13
5.319LeuGlu: 5.319 ± 1.165
1.995LeuPhe: 1.995 ± 0.767
3.324LeuGly: 3.324 ± 1.574
1.995LeuHis: 1.995 ± 0.475
5.984LeuIle: 5.984 ± 1.571
1.995LeuLys: 1.995 ± 1.385
4.654LeuLeu: 4.654 ± 0.727
1.995LeuMet: 1.995 ± 0.767
2.66LeuAsn: 2.66 ± 0.721
5.319LeuPro: 5.319 ± 1.429
2.66LeuGln: 2.66 ± 1.546
5.319LeuArg: 5.319 ± 0.872
7.314LeuSer: 7.314 ± 1.845
3.324LeuThr: 3.324 ± 0.663
4.654LeuVal: 4.654 ± 1.987
1.995LeuTrp: 1.995 ± 0.767
2.66LeuTyr: 2.66 ± 1.248
0.0LeuXaa: 0.0 ± 0.0
Met
1.33MetAla: 1.33 ± 0.828
0.665MetCys: 0.665 ± 0.745
0.665MetAsp: 0.665 ± 0.745
0.665MetGlu: 0.665 ± 0.462
0.0MetPhe: 0.0 ± 0.0
1.995MetGly: 1.995 ± 0.767
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.33MetLys: 1.33 ± 0.4
1.33MetLeu: 1.33 ± 0.4
0.0MetMet: 0.0 ± 0.0
0.665MetAsn: 0.665 ± 0.491
0.665MetPro: 0.665 ± 0.491
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.33MetSer: 1.33 ± 0.624
1.33MetThr: 1.33 ± 0.792
0.665MetVal: 0.665 ± 0.745
0.665MetTrp: 0.665 ± 0.745
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.66AsnAla: 2.66 ± 1.611
0.665AsnCys: 0.665 ± 0.462
0.0AsnAsp: 0.0 ± 0.0
0.665AsnGlu: 0.665 ± 0.491
1.995AsnPhe: 1.995 ± 1.004
1.995AsnGly: 1.995 ± 0.711
1.33AsnHis: 1.33 ± 0.923
0.665AsnIle: 0.665 ± 0.733
0.0AsnLys: 0.0 ± 0.0
1.33AsnLeu: 1.33 ± 0.828
0.665AsnMet: 0.665 ± 0.462
0.665AsnAsn: 0.665 ± 0.491
1.995AsnPro: 1.995 ± 1.069
1.33AsnGln: 1.33 ± 0.828
1.995AsnArg: 1.995 ± 0.767
4.654AsnSer: 4.654 ± 1.308
3.989AsnThr: 3.989 ± 1.702
1.995AsnVal: 1.995 ± 0.806
1.33AsnTrp: 1.33 ± 0.4
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.989ProAla: 3.989 ± 0.376
0.665ProCys: 0.665 ± 0.491
1.33ProAsp: 1.33 ± 0.981
3.989ProGlu: 3.989 ± 1.31
2.66ProPhe: 2.66 ± 0.439
5.984ProGly: 5.984 ± 1.144
1.33ProHis: 1.33 ± 0.4
0.0ProIle: 0.0 ± 0.0
1.995ProLys: 1.995 ± 0.767
4.654ProLeu: 4.654 ± 1.202
0.665ProMet: 0.665 ± 0.462
1.33ProAsn: 1.33 ± 0.624
5.319ProPro: 5.319 ± 2.388
1.995ProGln: 1.995 ± 0.475
5.319ProArg: 5.319 ± 1.475
8.644ProSer: 8.644 ± 2.811
5.984ProThr: 5.984 ± 1.447
5.984ProVal: 5.984 ± 1.618
0.665ProTrp: 0.665 ± 0.491
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.66GlnAla: 2.66 ± 1.546
0.0GlnCys: 0.0 ± 0.0
1.33GlnAsp: 1.33 ± 0.73
2.66GlnGlu: 2.66 ± 1.962
0.665GlnPhe: 0.665 ± 0.462
2.66GlnGly: 2.66 ± 1.184
0.665GlnHis: 0.665 ± 0.491
1.995GlnIle: 1.995 ± 0.711
1.33GlnLys: 1.33 ± 0.4
3.324GlnLeu: 3.324 ± 1.159
0.0GlnMet: 0.0 ± 0.0
0.665GlnAsn: 0.665 ± 0.491
1.33GlnPro: 1.33 ± 0.4
2.66GlnGln: 2.66 ± 1.611
1.33GlnArg: 1.33 ± 0.624
4.654GlnSer: 4.654 ± 1.831
1.995GlnThr: 1.995 ± 1.455
0.665GlnVal: 0.665 ± 0.733
0.665GlnTrp: 0.665 ± 0.491
1.33GlnTyr: 1.33 ± 0.923
0.0GlnXaa: 0.0 ± 0.0
Arg
3.324ArgAla: 3.324 ± 0.602
2.66ArgCys: 2.66 ± 1.212
3.324ArgAsp: 3.324 ± 0.769
4.654ArgGlu: 4.654 ± 1.255
5.984ArgPhe: 5.984 ± 1.273
6.649ArgGly: 6.649 ± 2.013
1.33ArgHis: 1.33 ± 0.923
3.324ArgIle: 3.324 ± 1.991
4.654ArgLys: 4.654 ± 0.79
5.319ArgLeu: 5.319 ± 1.069
0.665ArgMet: 0.665 ± 0.491
1.33ArgAsn: 1.33 ± 1.104
1.995ArgPro: 1.995 ± 1.719
0.665ArgGln: 0.665 ± 0.491
5.319ArgArg: 5.319 ± 1.783
3.989ArgSer: 3.989 ± 2.057
3.324ArgThr: 3.324 ± 0.765
5.984ArgVal: 5.984 ± 1.755
0.665ArgTrp: 0.665 ± 0.745
3.989ArgTyr: 3.989 ± 1.2
0.0ArgXaa: 0.0 ± 0.0
Ser
10.638SerAla: 10.638 ± 3.178
0.665SerCys: 0.665 ± 0.462
3.324SerAsp: 3.324 ± 1.743
3.989SerGlu: 3.989 ± 2.139
2.66SerPhe: 2.66 ± 1.444
10.638SerGly: 10.638 ± 0.902
2.66SerHis: 2.66 ± 0.8
2.66SerIle: 2.66 ± 2.018
5.984SerLys: 5.984 ± 1.818
9.309SerLeu: 9.309 ± 2.67
3.324SerMet: 3.324 ± 1.89
4.654SerAsn: 4.654 ± 1.202
3.989SerPro: 3.989 ± 1.422
1.995SerGln: 1.995 ± 1.069
7.314SerArg: 7.314 ± 1.091
14.628SerSer: 14.628 ± 2.705
6.649SerThr: 6.649 ± 1.234
11.968SerVal: 11.968 ± 0.985
1.995SerTrp: 1.995 ± 0.767
1.995SerTyr: 1.995 ± 0.767
0.0SerXaa: 0.0 ± 0.0
Thr
3.989ThrAla: 3.989 ± 1.618
2.66ThrCys: 2.66 ± 0.715
0.665ThrAsp: 0.665 ± 0.462
1.995ThrGlu: 1.995 ± 0.711
0.665ThrPhe: 0.665 ± 0.462
2.66ThrGly: 2.66 ± 0.738
0.665ThrHis: 0.665 ± 0.733
2.66ThrIle: 2.66 ± 1.184
0.665ThrLys: 0.665 ± 0.462
2.66ThrLeu: 2.66 ± 0.439
0.0ThrMet: 0.0 ± 0.696
1.995ThrAsn: 1.995 ± 0.475
4.654ThrPro: 4.654 ± 0.727
1.995ThrGln: 1.995 ± 1.069
5.319ThrArg: 5.319 ± 1.526
7.314ThrSer: 7.314 ± 1.345
4.654ThrThr: 4.654 ± 2.44
3.989ThrVal: 3.989 ± 2.391
3.989ThrTrp: 3.989 ± 1.31
0.665ThrTyr: 0.665 ± 0.745
0.0ThrXaa: 0.0 ± 0.0
Val
5.319ValAla: 5.319 ± 2.068
2.66ValCys: 2.66 ± 1.402
5.984ValAsp: 5.984 ± 0.757
7.314ValGlu: 7.314 ± 1.845
1.995ValPhe: 1.995 ± 1.472
5.319ValGly: 5.319 ± 0.997
0.665ValHis: 0.665 ± 0.733
4.654ValIle: 4.654 ± 1.628
4.654ValLys: 4.654 ± 1.255
3.989ValLeu: 3.989 ± 1.731
0.0ValMet: 0.0 ± 0.0
2.66ValAsn: 2.66 ± 0.721
6.649ValPro: 6.649 ± 1.531
3.324ValGln: 3.324 ± 0.663
4.654ValArg: 4.654 ± 0.727
9.309ValSer: 9.309 ± 2.301
1.995ValThr: 1.995 ± 1.294
6.649ValVal: 6.649 ± 1.77
2.66ValTrp: 2.66 ± 1.668
1.33ValTyr: 1.33 ± 1.104
0.0ValXaa: 0.0 ± 0.0
Trp
1.33TrpAla: 1.33 ± 0.923
0.665TrpCys: 0.665 ± 0.491
2.66TrpAsp: 2.66 ± 1.212
0.665TrpGlu: 0.665 ± 0.491
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.665TrpHis: 0.665 ± 0.733
1.33TrpIle: 1.33 ± 0.4
1.33TrpLys: 1.33 ± 1.49
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.66TrpPro: 2.66 ± 1.546
0.665TrpGln: 0.665 ± 0.491
0.665TrpArg: 0.665 ± 0.491
3.989TrpSer: 3.989 ± 0.85
1.33TrpThr: 1.33 ± 0.981
2.66TrpVal: 2.66 ± 1.254
0.665TrpTrp: 0.665 ± 0.491
1.33TrpTyr: 1.33 ± 0.624
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.995TyrAla: 1.995 ± 0.475
1.33TyrCys: 1.33 ± 0.981
3.989TyrAsp: 3.989 ± 1.511
0.665TyrGlu: 0.665 ± 0.462
1.33TyrPhe: 1.33 ± 0.792
1.995TyrGly: 1.995 ± 0.806
1.995TyrHis: 1.995 ± 1.385
0.0TyrIle: 0.0 ± 0.0
0.665TyrLys: 0.665 ± 0.462
2.66TyrLeu: 2.66 ± 1.611
0.0TyrMet: 0.0 ± 0.0
1.33TyrAsn: 1.33 ± 0.923
1.33TyrPro: 1.33 ± 0.981
0.0TyrGln: 0.0 ± 0.0
0.0TyrArg: 0.0 ± 0.0
1.33TyrSer: 1.33 ± 0.624
1.33TyrThr: 1.33 ± 1.467
2.66TyrVal: 2.66 ± 0.439
0.0TyrTrp: 0.0 ± 0.0
1.995TyrTyr: 1.995 ± 1.004
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski