Amino acid dipepetide frequency for Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.593AlaAla: 6.593 ± 0.062	1.103AlaCys: 1.103 ± 0.015	3.354AlaAsp: 3.354 ± 0.025	4.288AlaGlu: 4.288 ± 0.027	2.343AlaPhe: 2.343 ± 0.019	4.035AlaGly: 4.035 ± 0.029	1.447AlaHis: 1.447 ± 0.017	3.622AlaIle: 3.622 ± 0.024	4.002AlaLys: 4.002 ± 0.027	5.848AlaLeu: 5.848 ± 0.038	1.633AlaMet: 1.633 ± 0.016	3.0AlaAsn: 3.0 ± 0.022	3.403AlaPro: 3.403 ± 0.035	2.549AlaGln: 2.549 ± 0.022	3.119AlaArg: 3.119 ± 0.022	5.307AlaSer: 5.307 ± 0.037	4.129AlaThr: 4.129 ± 0.032	4.612AlaVal: 4.612 ± 0.035	0.573AlaTrp: 0.573 ± 0.009	1.754AlaTyr: 1.754 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	1.139CysAla: 1.139 ± 0.013	0.494CysCys: 0.494 ± 0.011	1.273CysAsp: 1.273 ± 0.022	1.212CysGlu: 1.212 ± 0.019	0.772CysPhe: 0.772 ± 0.011	1.417CysGly: 1.417 ± 0.019	0.492CysHis: 0.492 ± 0.009	0.985CysIle: 0.985 ± 0.014	1.017CysLys: 1.017 ± 0.015	1.748CysLeu: 1.748 ± 0.02	0.414CysMet: 0.414 ± 0.008	0.904CysAsn: 0.904 ± 0.015	1.073CysPro: 1.073 ± 0.018	0.732CysGln: 0.732 ± 0.013	1.125CysArg: 1.125 ± 0.014	1.608CysSer: 1.608 ± 0.021	1.022CysThr: 1.022 ± 0.014	1.212CysVal: 1.212 ± 0.018	0.226CysTrp: 0.226 ± 0.006	0.613CysTyr: 0.613 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.289AspAla: 3.289 ± 0.022	1.061AspCys: 1.061 ± 0.012	4.404AspAsp: 4.404 ± 0.045	4.623AspGlu: 4.623 ± 0.038	2.34AspPhe: 2.34 ± 0.021	3.421AspGly: 3.421 ± 0.03	1.302AspHis: 1.302 ± 0.014	3.061AspIle: 3.061 ± 0.022	2.978AspLys: 2.978 ± 0.025	4.834AspLeu: 4.834 ± 0.033	1.291AspMet: 1.291 ± 0.015	2.415AspAsn: 2.415 ± 0.021	2.635AspPro: 2.635 ± 0.021	2.051AspGln: 2.051 ± 0.017	3.06AspArg: 3.06 ± 0.023	4.299AspSer: 4.299 ± 0.033	2.556AspThr: 2.556 ± 0.018	3.595AspVal: 3.595 ± 0.024	0.64AspTrp: 0.64 ± 0.01	1.914AspTyr: 1.914 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.286GluAla: 4.286 ± 0.032	1.256GluCys: 1.256 ± 0.018	4.228GluAsp: 4.228 ± 0.032	6.083GluGlu: 6.083 ± 0.057	2.336GluPhe: 2.336 ± 0.02	3.043GluGly: 3.043 ± 0.026	1.532GluHis: 1.532 ± 0.017	3.681GluIle: 3.681 ± 0.029	4.711GluLys: 4.711 ± 0.04	5.924GluLeu: 5.924 ± 0.037	1.755GluMet: 1.755 ± 0.017	3.228GluAsn: 3.228 ± 0.024	2.825GluPro: 2.825 ± 0.031	3.053GluGln: 3.053 ± 0.025	3.734GluArg: 3.734 ± 0.029	4.556GluSer: 4.556 ± 0.034	3.483GluThr: 3.483 ± 0.027	3.902GluVal: 3.902 ± 0.031	0.629GluTrp: 0.629 ± 0.011	2.0GluTyr: 2.0 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.318PheAla: 2.318 ± 0.019	0.816PheCys: 0.816 ± 0.011	2.262PheAsp: 2.262 ± 0.02	2.35PheGlu: 2.35 ± 0.021	1.577PhePhe: 1.577 ± 0.017	2.571PheGly: 2.571 ± 0.028	1.005PheHis: 1.005 ± 0.011	2.047PheIle: 2.047 ± 0.018	2.152PheLys: 2.152 ± 0.021	3.565PheLeu: 3.565 ± 0.032	0.878PheMet: 0.878 ± 0.012	1.9PheAsn: 1.9 ± 0.019	1.715PhePro: 1.715 ± 0.016	1.548PheGln: 1.548 ± 0.015	2.166PheArg: 2.166 ± 0.018	2.896PheSer: 2.896 ± 0.02	2.053PheThr: 2.053 ± 0.019	2.635PheVal: 2.635 ± 0.022	0.483PheTrp: 0.483 ± 0.01	1.365PheTyr: 1.365 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	3.767GlyAla: 3.767 ± 0.032	1.071GlyCys: 1.071 ± 0.016	2.993GlyAsp: 2.993 ± 0.027	3.224GlyGlu: 3.224 ± 0.024	2.383GlyPhe: 2.383 ± 0.02	5.524GlyGly: 5.524 ± 0.068	1.526GlyHis: 1.526 ± 0.018	3.039GlyIle: 3.039 ± 0.024	3.466GlyLys: 3.466 ± 0.024	4.488GlyLeu: 4.488 ± 0.03	1.434GlyMet: 1.434 ± 0.019	2.795GlyAsn: 2.795 ± 0.023	2.51GlyPro: 2.51 ± 0.028	2.142GlyGln: 2.142 ± 0.021	3.032GlyArg: 3.032 ± 0.021	5.27GlySer: 5.27 ± 0.042	3.391GlyThr: 3.391 ± 0.026	3.499GlyVal: 3.499 ± 0.027	0.662GlyTrp: 0.662 ± 0.012	1.986GlyTyr: 1.986 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.367HisAla: 1.367 ± 0.015	0.569HisCys: 0.569 ± 0.01	1.176HisAsp: 1.176 ± 0.014	1.391HisGlu: 1.391 ± 0.016	1.072HisPhe: 1.072 ± 0.014	1.472HisGly: 1.472 ± 0.015	1.448HisHis: 1.448 ± 0.025	1.345HisIle: 1.345 ± 0.015	1.343HisLys: 1.343 ± 0.018	2.455HisLeu: 2.455 ± 0.022	0.695HisMet: 0.695 ± 0.011	1.082HisAsn: 1.082 ± 0.015	1.508HisPro: 1.508 ± 0.016	1.45HisGln: 1.45 ± 0.019	1.597HisArg: 1.597 ± 0.016	1.985HisSer: 1.985 ± 0.02	1.268HisThr: 1.268 ± 0.013	1.511HisVal: 1.511 ± 0.016	0.287HisTrp: 0.287 ± 0.007	0.881HisTyr: 0.881 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.632IleAla: 3.632 ± 0.023	1.285IleCys: 1.285 ± 0.016	3.121IleAsp: 3.121 ± 0.027	3.448IleGlu: 3.448 ± 0.028	2.066IlePhe: 2.066 ± 0.022	2.921IleGly: 2.921 ± 0.02	1.334IleHis: 1.334 ± 0.014	2.835IleIle: 2.835 ± 0.022	3.131IleLys: 3.131 ± 0.026	4.646IleLeu: 4.646 ± 0.03	1.142IleMet: 1.142 ± 0.015	2.563IleAsn: 2.563 ± 0.021	2.941IlePro: 2.941 ± 0.021	2.214IleGln: 2.214 ± 0.019	3.005IleArg: 3.005 ± 0.021	4.064IleSer: 4.064 ± 0.03	2.965IleThr: 2.965 ± 0.025	3.618IleVal: 3.618 ± 0.028	0.517IleTrp: 0.517 ± 0.01	1.66IleTyr: 1.66 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.756LysAla: 3.756 ± 0.027	1.268LysCys: 1.268 ± 0.018	3.255LysAsp: 3.255 ± 0.026	4.267LysGlu: 4.267 ± 0.038	2.266LysPhe: 2.266 ± 0.021	2.591LysGly: 2.591 ± 0.02	1.67LysHis: 1.67 ± 0.018	3.412LysIle: 3.412 ± 0.026	4.945LysLys: 4.945 ± 0.048	5.752LysLeu: 5.752 ± 0.034	1.574LysMet: 1.574 ± 0.014	2.81LysAsn: 2.81 ± 0.021	3.267LysPro: 3.267 ± 0.033	2.883LysGln: 2.883 ± 0.023	3.833LysArg: 3.833 ± 0.027	4.509LysSer: 4.509 ± 0.034	3.394LysThr: 3.394 ± 0.026	3.649LysVal: 3.649 ± 0.029	0.645LysTrp: 0.645 ± 0.01	2.042LysTyr: 2.042 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	6.009LeuAla: 6.009 ± 0.038	1.682LeuCys: 1.682 ± 0.019	4.909LeuAsp: 4.909 ± 0.034	6.065LeuGlu: 6.065 ± 0.038	3.269LeuPhe: 3.269 ± 0.03	4.55LeuGly: 4.55 ± 0.032	2.253LeuHis: 2.253 ± 0.023	4.416LeuIle: 4.416 ± 0.033	6.0LeuLys: 6.0 ± 0.037	8.485LeuLeu: 8.485 ± 0.061	2.13LeuMet: 2.13 ± 0.019	4.272LeuAsn: 4.272 ± 0.03	4.547LeuPro: 4.547 ± 0.027	4.374LeuGln: 4.374 ± 0.033	5.102LeuArg: 5.102 ± 0.033	6.545LeuSer: 6.545 ± 0.039	4.801LeuThr: 4.801 ± 0.027	5.458LeuVal: 5.458 ± 0.035	0.878LeuTrp: 0.878 ± 0.012	2.532LeuTyr: 2.532 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.788MetAla: 1.788 ± 0.015	0.417MetCys: 0.417 ± 0.008	1.439MetAsp: 1.439 ± 0.015	1.678MetGlu: 1.678 ± 0.019	0.957MetPhe: 0.957 ± 0.012	1.293MetGly: 1.293 ± 0.017	0.568MetHis: 0.568 ± 0.009	1.278MetIle: 1.278 ± 0.015	1.631MetLys: 1.631 ± 0.015	2.169MetLeu: 2.169 ± 0.018	0.751MetMet: 0.751 ± 0.014	1.145MetAsn: 1.145 ± 0.012	1.069MetPro: 1.069 ± 0.015	1.034MetGln: 1.034 ± 0.013	1.257MetArg: 1.257 ± 0.014	1.704MetSer: 1.704 ± 0.016	1.304MetThr: 1.304 ± 0.014	1.521MetVal: 1.521 ± 0.014	0.243MetTrp: 0.243 ± 0.006	0.706MetTyr: 0.706 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.936AsnAla: 2.936 ± 0.021	0.954AsnCys: 0.954 ± 0.014	2.559AsnAsp: 2.559 ± 0.02	2.926AsnGlu: 2.926 ± 0.023	1.903AsnPhe: 1.903 ± 0.018	3.334AsnGly: 3.334 ± 0.028	1.215AsnHis: 1.215 ± 0.013	2.621AsnIle: 2.621 ± 0.023	2.516AsnLys: 2.516 ± 0.023	4.312AsnLeu: 4.312 ± 0.029	1.111AsnMet: 1.111 ± 0.014	2.914AsnAsn: 2.914 ± 0.033	2.443AsnPro: 2.443 ± 0.023	2.03AsnGln: 2.03 ± 0.019	2.685AsnArg: 2.685 ± 0.022	3.835AsnSer: 3.835 ± 0.033	2.368AsnThr: 2.368 ± 0.021	3.119AsnVal: 3.119 ± 0.024	0.51AsnTrp: 0.51 ± 0.011	1.6AsnTyr: 1.6 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	3.726ProAla: 3.726 ± 0.036	0.693ProCys: 0.693 ± 0.013	2.688ProAsp: 2.688 ± 0.02	3.663ProGlu: 3.663 ± 0.032	1.767ProPhe: 1.767 ± 0.017	2.801ProGly: 2.801 ± 0.034	1.182ProHis: 1.182 ± 0.015	2.574ProIle: 2.574 ± 0.022	3.191ProLys: 3.191 ± 0.026	4.05ProLeu: 4.05 ± 0.027	1.154ProMet: 1.154 ± 0.015	2.36ProAsn: 2.36 ± 0.024	4.285ProPro: 4.285 ± 0.056	2.307ProGln: 2.307 ± 0.029	2.333ProArg: 2.333 ± 0.02	4.581ProSer: 4.581 ± 0.042	3.357ProThr: 3.357 ± 0.032	3.646ProVal: 3.646 ± 0.035	0.477ProTrp: 0.477 ± 0.008	1.514ProTyr: 1.514 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	2.587GlnAla: 2.587 ± 0.023	0.889GlnCys: 0.889 ± 0.015	1.885GlnAsp: 1.885 ± 0.016	2.776GlnGlu: 2.776 ± 0.024	1.603GlnPhe: 1.603 ± 0.016	1.82GlnGly: 1.82 ± 0.019	1.44GlnHis: 1.44 ± 0.019	2.36GlnIle: 2.36 ± 0.022	2.668GlnLys: 2.668 ± 0.025	4.271GlnLeu: 4.271 ± 0.03	1.161GlnMet: 1.161 ± 0.014	2.108GlnAsn: 2.108 ± 0.022	2.474GlnPro: 2.474 ± 0.031	4.493GlnGln: 4.493 ± 0.102	2.532GlnArg: 2.532 ± 0.021	3.158GlnSer: 3.158 ± 0.027	2.312GlnThr: 2.312 ± 0.02	2.295GlnVal: 2.295 ± 0.022	0.457GlnTrp: 0.457 ± 0.008	1.408GlnTyr: 1.408 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	3.008ArgAla: 3.008 ± 0.022	1.141ArgCys: 1.141 ± 0.017	2.845ArgAsp: 2.845 ± 0.023	3.387ArgGlu: 3.387 ± 0.023	2.337ArgPhe: 2.337 ± 0.021	2.719ArgGly: 2.719 ± 0.025	1.527ArgHis: 1.527 ± 0.015	3.014ArgIle: 3.014 ± 0.023	4.156ArgLys: 4.156 ± 0.027	4.837ArgLeu: 4.837 ± 0.032	1.401ArgMet: 1.401 ± 0.015	2.878ArgAsn: 2.878 ± 0.023	2.608ArgPro: 2.608 ± 0.034	2.379ArgGln: 2.379 ± 0.019	3.972ArgArg: 3.972 ± 0.031	4.357ArgSer: 4.357 ± 0.039	2.926ArgThr: 2.926 ± 0.023	2.935ArgVal: 2.935 ± 0.023	0.64ArgTrp: 0.64 ± 0.01	1.877ArgTyr: 1.877 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	5.336SerAla: 5.336 ± 0.036	1.38SerCys: 1.38 ± 0.016	4.419SerAsp: 4.419 ± 0.032	4.62SerGlu: 4.62 ± 0.036	2.948SerPhe: 2.948 ± 0.022	5.309SerGly: 5.309 ± 0.044	1.873SerHis: 1.873 ± 0.018	3.977SerIle: 3.977 ± 0.023	4.55SerLys: 4.55 ± 0.031	6.564SerLeu: 6.564 ± 0.039	1.74SerMet: 1.74 ± 0.016	3.978SerAsn: 3.978 ± 0.029	4.257SerPro: 4.257 ± 0.046	3.023SerGln: 3.023 ± 0.024	4.081SerArg: 4.081 ± 0.036	9.695SerSer: 9.695 ± 0.106	5.234SerThr: 5.234 ± 0.04	4.761SerVal: 4.761 ± 0.028	0.751SerTrp: 0.751 ± 0.012	2.277SerTyr: 2.277 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.213ThrAla: 4.213 ± 0.029	1.046ThrCys: 1.046 ± 0.018	2.836ThrAsp: 2.836 ± 0.022	3.46ThrGlu: 3.46 ± 0.025	2.115ThrPhe: 2.115 ± 0.018	3.398ThrGly: 3.398 ± 0.024	1.241ThrHis: 1.241 ± 0.014	3.284ThrIle: 3.284 ± 0.025	3.195ThrLys: 3.195 ± 0.023	4.845ThrLeu: 4.845 ± 0.031	1.259ThrMet: 1.259 ± 0.014	2.61ThrAsn: 2.61 ± 0.022	3.484ThrPro: 3.484 ± 0.04	1.948ThrGln: 1.948 ± 0.017	2.544ThrArg: 2.544 ± 0.019	4.854ThrSer: 4.854 ± 0.037	4.564ThrThr: 4.564 ± 0.064	4.042ThrVal: 4.042 ± 0.03	0.513ThrTrp: 0.513 ± 0.009	1.542ThrTyr: 1.542 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	4.585ValAla: 4.585 ± 0.035	1.423ValCys: 1.423 ± 0.018	3.679ValAsp: 3.679 ± 0.027	4.26ValGlu: 4.26 ± 0.03	2.422ValPhe: 2.422 ± 0.023	3.432ValGly: 3.432 ± 0.025	1.625ValHis: 1.625 ± 0.017	3.346ValIle: 3.346 ± 0.027	3.775ValLys: 3.775 ± 0.026	5.689ValLeu: 5.689 ± 0.041	1.403ValMet: 1.403 ± 0.016	2.76ValAsn: 2.76 ± 0.022	3.449ValPro: 3.449 ± 0.029	2.722ValGln: 2.722 ± 0.019	3.238ValArg: 3.238 ± 0.024	4.55ValSer: 4.55 ± 0.022	3.665ValThr: 3.665 ± 0.025	4.595ValVal: 4.595 ± 0.032	0.646ValTrp: 0.646 ± 0.011	1.868ValTyr: 1.868 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.557TrpAla: 0.557 ± 0.01	0.198TrpCys: 0.198 ± 0.005	0.567TrpAsp: 0.567 ± 0.01	0.598TrpGlu: 0.598 ± 0.01	0.448TrpPhe: 0.448 ± 0.008	0.548TrpGly: 0.548 ± 0.01	0.279TrpHis: 0.279 ± 0.007	0.677TrpIle: 0.677 ± 0.012	0.702TrpLys: 0.702 ± 0.012	0.961TrpLeu: 0.961 ± 0.013	0.311TrpMet: 0.311 ± 0.007	0.609TrpAsn: 0.609 ± 0.011	0.42TrpPro: 0.42 ± 0.008	0.405TrpGln: 0.405 ± 0.008	0.628TrpArg: 0.628 ± 0.009	0.731TrpSer: 0.731 ± 0.011	0.604TrpThr: 0.604 ± 0.013	0.58TrpVal: 0.58 ± 0.008	0.166TrpTrp: 0.166 ± 0.005	0.345TrpTyr: 0.345 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.821TyrAla: 1.821 ± 0.021	0.73TyrCys: 0.73 ± 0.012	1.876TyrAsp: 1.876 ± 0.019	1.925TyrGlu: 1.925 ± 0.018	1.376TyrPhe: 1.376 ± 0.017	2.002TyrGly: 2.002 ± 0.019	0.942TyrHis: 0.942 ± 0.012	1.534TyrIle: 1.534 ± 0.013	1.658TyrLys: 1.658 ± 0.018	2.837TyrLeu: 2.837 ± 0.024	0.715TyrMet: 0.715 ± 0.011	1.561TyrAsn: 1.561 ± 0.019	1.436TyrPro: 1.436 ± 0.018	1.36TyrGln: 1.36 ± 0.016	1.899TyrArg: 1.899 ± 0.019	2.27TyrSer: 2.27 ± 0.02	1.596TyrThr: 1.596 ± 0.016	1.949TyrVal: 1.949 ± 0.019	0.394TyrTrp: 0.394 ± 0.01	1.268TyrTyr: 1.268 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16616 proteins (7624980 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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