Amino acid dipepetide frequency for Acrocarpospora corrugata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.465AlaAla: 19.465 ± 0.122	1.066AlaCys: 1.066 ± 0.023	7.988AlaAsp: 7.988 ± 0.052	8.465AlaGlu: 8.465 ± 0.071	3.623AlaPhe: 3.623 ± 0.041	12.524AlaGly: 12.524 ± 0.086	2.563AlaHis: 2.563 ± 0.032	4.909AlaIle: 4.909 ± 0.05	2.858AlaLys: 2.858 ± 0.041	13.914AlaLeu: 13.914 ± 0.092	2.579AlaMet: 2.579 ± 0.031	2.35AlaAsn: 2.35 ± 0.039	5.895AlaPro: 5.895 ± 0.044	3.633AlaGln: 3.633 ± 0.04	9.687AlaArg: 9.687 ± 0.072	5.693AlaSer: 5.693 ± 0.056	7.296AlaThr: 7.296 ± 0.05	11.135AlaVal: 11.135 ± 0.066	1.921AlaTrp: 1.921 ± 0.032	2.737AlaTyr: 2.737 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.038CysAla: 1.038 ± 0.019	0.104CysCys: 0.104 ± 0.006	0.492CysAsp: 0.492 ± 0.013	0.392CysGlu: 0.392 ± 0.013	0.223CysPhe: 0.223 ± 0.008	0.93CysGly: 0.93 ± 0.02	0.225CysHis: 0.225 ± 0.009	0.138CysIle: 0.138 ± 0.008	0.101CysLys: 0.101 ± 0.006	0.737CysLeu: 0.737 ± 0.019	0.118CysMet: 0.118 ± 0.007	0.126CysAsn: 0.126 ± 0.008	0.506CysPro: 0.506 ± 0.013	0.206CysGln: 0.206 ± 0.01	0.583CysArg: 0.583 ± 0.016	0.406CysSer: 0.406 ± 0.011	0.442CysThr: 0.442 ± 0.013	0.658CysVal: 0.658 ± 0.016	0.145CysTrp: 0.145 ± 0.009	0.167CysTyr: 0.167 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	6.751AspAla: 6.751 ± 0.056	0.409AspCys: 0.409 ± 0.013	3.415AspAsp: 3.415 ± 0.044	3.567AspGlu: 3.567 ± 0.04	1.679AspPhe: 1.679 ± 0.029	5.898AspGly: 5.898 ± 0.06	1.412AspHis: 1.412 ± 0.024	2.012AspIle: 2.012 ± 0.03	1.027AspLys: 1.027 ± 0.023	6.879AspLeu: 6.879 ± 0.058	0.833AspMet: 0.833 ± 0.014	1.032AspAsn: 1.032 ± 0.024	4.582AspPro: 4.582 ± 0.046	1.885AspGln: 1.885 ± 0.03	4.837AspArg: 4.837 ± 0.048	2.458AspSer: 2.458 ± 0.033	2.707AspThr: 2.707 ± 0.033	4.671AspVal: 4.671 ± 0.045	1.017AspTrp: 1.017 ± 0.021	1.25AspTyr: 1.25 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.475GluAla: 6.475 ± 0.054	0.346GluCys: 0.346 ± 0.011	2.551GluAsp: 2.551 ± 0.03	3.037GluGlu: 3.037 ± 0.039	1.679GluPhe: 1.679 ± 0.027	3.64GluGly: 3.64 ± 0.04	1.455GluHis: 1.455 ± 0.023	2.727GluIle: 2.727 ± 0.031	1.175GluLys: 1.175 ± 0.025	6.895GluLeu: 6.895 ± 0.06	0.949GluMet: 0.949 ± 0.019	1.133GluAsn: 1.133 ± 0.022	3.274GluPro: 3.274 ± 0.042	2.036GluGln: 2.036 ± 0.031	5.02GluArg: 5.02 ± 0.056	2.634GluSer: 2.634 ± 0.034	2.815GluThr: 2.815 ± 0.039	4.441GluVal: 4.441 ± 0.045	0.803GluTrp: 0.803 ± 0.017	1.093GluTyr: 1.093 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.955PheAla: 3.955 ± 0.041	0.282PheCys: 0.282 ± 0.011	2.155PheAsp: 2.155 ± 0.028	1.466PheGlu: 1.466 ± 0.026	0.94PhePhe: 0.94 ± 0.021	3.206PheGly: 3.206 ± 0.039	0.637PheHis: 0.637 ± 0.017	0.914PheIle: 0.914 ± 0.024	0.542PheLys: 0.542 ± 0.015	2.746PheLeu: 2.746 ± 0.04	0.447PheMet: 0.447 ± 0.012	0.692PheAsn: 0.692 ± 0.02	1.499PhePro: 1.499 ± 0.025	0.789PheGln: 0.789 ± 0.018	1.974PheArg: 1.974 ± 0.025	1.515PheSer: 1.515 ± 0.027	2.195PheThr: 2.195 ± 0.031	2.339PheVal: 2.339 ± 0.032	0.487PheTrp: 0.487 ± 0.014	0.632PheTyr: 0.632 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	9.714GlyAla: 9.714 ± 0.068	0.781GlyCys: 0.781 ± 0.019	5.246GlyAsp: 5.246 ± 0.053	5.029GlyGlu: 5.029 ± 0.046	3.026GlyPhe: 3.026 ± 0.037	8.323GlyGly: 8.323 ± 0.074	2.193GlyHis: 2.193 ± 0.032	3.543GlyIle: 3.543 ± 0.046	2.343GlyLys: 2.343 ± 0.034	9.737GlyLeu: 9.737 ± 0.076	1.979GlyMet: 1.979 ± 0.029	1.992GlyAsn: 1.992 ± 0.042	4.862GlyPro: 4.862 ± 0.049	2.896GlyGln: 2.896 ± 0.036	7.321GlyArg: 7.321 ± 0.063	5.163GlySer: 5.163 ± 0.051	5.708GlyThr: 5.708 ± 0.063	7.799GlyVal: 7.799 ± 0.065	1.759GlyTrp: 1.759 ± 0.029	2.436GlyTyr: 2.436 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.568HisAla: 2.568 ± 0.033	0.201HisCys: 0.201 ± 0.009	1.317HisAsp: 1.317 ± 0.023	1.156HisGlu: 1.156 ± 0.022	0.606HisPhe: 0.606 ± 0.016	2.13HisGly: 2.13 ± 0.032	0.662HisHis: 0.662 ± 0.019	0.724HisIle: 0.724 ± 0.017	0.298HisLys: 0.298 ± 0.01	2.449HisLeu: 2.449 ± 0.027	0.315HisMet: 0.315 ± 0.01	0.401HisAsn: 0.401 ± 0.012	1.733HisPro: 1.733 ± 0.026	0.66HisGln: 0.66 ± 0.016	1.921HisArg: 1.921 ± 0.028	0.929HisSer: 0.929 ± 0.018	1.154HisThr: 1.154 ± 0.022	1.676HisVal: 1.676 ± 0.028	0.347HisTrp: 0.347 ± 0.011	0.475HisTyr: 0.475 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	5.562IleAla: 5.562 ± 0.045	0.336IleCys: 0.336 ± 0.011	2.617IleAsp: 2.617 ± 0.035	2.399IleGlu: 2.399 ± 0.031	1.026IlePhe: 1.026 ± 0.023	3.974IleGly: 3.974 ± 0.047	0.724IleHis: 0.724 ± 0.017	1.334IleIle: 1.334 ± 0.027	0.901IleLys: 0.901 ± 0.021	3.198IleLeu: 3.198 ± 0.043	0.684IleMet: 0.684 ± 0.017	0.884IleAsn: 0.884 ± 0.021	2.314IlePro: 2.314 ± 0.029	0.965IleGln: 0.965 ± 0.023	2.928IleArg: 2.928 ± 0.034	2.209IleSer: 2.209 ± 0.029	2.759IleThr: 2.759 ± 0.037	3.399IleVal: 3.399 ± 0.035	0.562IleTrp: 0.562 ± 0.016	0.744IleTyr: 0.744 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	2.593LysAla: 2.593 ± 0.035	0.133LysCys: 0.133 ± 0.008	1.078LysAsp: 1.078 ± 0.021	1.027LysGlu: 1.027 ± 0.019	0.494LysPhe: 0.494 ± 0.013	1.583LysGly: 1.583 ± 0.028	0.416LysHis: 0.416 ± 0.012	1.109LysIle: 1.109 ± 0.022	0.626LysLys: 0.626 ± 0.02	2.052LysLeu: 2.052 ± 0.03	0.386LysMet: 0.386 ± 0.011	0.513LysAsn: 0.513 ± 0.017	1.41LysPro: 1.41 ± 0.026	0.613LysGln: 0.613 ± 0.015	1.472LysArg: 1.472 ± 0.025	1.158LysSer: 1.158 ± 0.024	1.28LysThr: 1.28 ± 0.025	1.884LysVal: 1.884 ± 0.031	0.298LysTrp: 0.298 ± 0.011	0.454LysTyr: 0.454 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	15.92LeuAla: 15.92 ± 0.098	0.782LeuCys: 0.782 ± 0.02	6.655LeuAsp: 6.655 ± 0.062	4.501LeuGlu: 4.501 ± 0.047	2.775LeuPhe: 2.775 ± 0.038	9.378LeuGly: 9.378 ± 0.074	2.054LeuHis: 2.054 ± 0.026	4.317LeuIle: 4.317 ± 0.053	1.926LeuLys: 1.926 ± 0.031	11.191LeuLeu: 11.191 ± 0.099	1.697LeuMet: 1.697 ± 0.023	2.062LeuAsn: 2.062 ± 0.027	6.458LeuPro: 6.458 ± 0.053	2.147LeuGln: 2.147 ± 0.028	8.825LeuArg: 8.825 ± 0.073	5.691LeuSer: 5.691 ± 0.043	7.301LeuThr: 7.301 ± 0.059	8.844LeuVal: 8.844 ± 0.063	1.373LeuTrp: 1.373 ± 0.024	1.882LeuTyr: 1.882 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.399MetAla: 2.399 ± 0.031	0.119MetCys: 0.119 ± 0.007	0.895MetAsp: 0.895 ± 0.02	0.74MetGlu: 0.74 ± 0.017	0.548MetPhe: 0.548 ± 0.015	1.351MetGly: 1.351 ± 0.023	0.362MetHis: 0.362 ± 0.012	0.926MetIle: 0.926 ± 0.02	0.437MetLys: 0.437 ± 0.012	1.897MetLeu: 1.897 ± 0.027	0.313MetMet: 0.313 ± 0.011	0.494MetAsn: 0.494 ± 0.014	1.125MetPro: 1.125 ± 0.02	0.395MetGln: 0.395 ± 0.013	1.539MetArg: 1.539 ± 0.023	1.296MetSer: 1.296 ± 0.021	1.531MetThr: 1.531 ± 0.026	1.401MetVal: 1.401 ± 0.024	0.236MetTrp: 0.236 ± 0.009	0.315MetTyr: 0.315 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.403AsnAla: 2.403 ± 0.039	0.172AsnCys: 0.172 ± 0.007	1.055AsnAsp: 1.055 ± 0.022	0.908AsnGlu: 0.908 ± 0.021	0.558AsnPhe: 0.558 ± 0.015	2.162AsnGly: 2.162 ± 0.045	0.428AsnHis: 0.428 ± 0.012	0.764AsnIle: 0.764 ± 0.018	0.399AsnLys: 0.399 ± 0.013	2.098AsnLeu: 2.098 ± 0.029	0.336AsnMet: 0.336 ± 0.011	0.568AsnAsn: 0.568 ± 0.024	1.685AsnPro: 1.685 ± 0.028	0.681AsnGln: 0.681 ± 0.019	1.526AsnArg: 1.526 ± 0.028	1.051AsnSer: 1.051 ± 0.022	1.213AsnThr: 1.213 ± 0.028	1.639AsnVal: 1.639 ± 0.028	0.375AsnTrp: 0.375 ± 0.014	0.477AsnTyr: 0.477 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	8.229ProAla: 8.229 ± 0.068	0.352ProCys: 0.352 ± 0.012	4.37ProAsp: 4.37 ± 0.045	4.045ProGlu: 4.045 ± 0.04	1.685ProPhe: 1.685 ± 0.028	6.671ProGly: 6.671 ± 0.061	1.18ProHis: 1.18 ± 0.023	2.112ProIle: 2.112 ± 0.027	1.244ProLys: 1.244 ± 0.021	5.133ProLeu: 5.133 ± 0.047	1.155ProMet: 1.155 ± 0.023	1.141ProAsn: 1.141 ± 0.026	3.876ProPro: 3.876 ± 0.065	1.591ProGln: 1.591 ± 0.032	3.7ProArg: 3.7 ± 0.036	3.395ProSer: 3.395 ± 0.05	3.233ProThr: 3.233 ± 0.046	5.105ProVal: 5.105 ± 0.046	0.94ProTrp: 0.94 ± 0.016	1.475ProTyr: 1.475 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.966GlnAla: 3.966 ± 0.037	0.164GlnCys: 0.164 ± 0.008	1.335GlnAsp: 1.335 ± 0.023	1.388GlnGlu: 1.388 ± 0.022	0.787GlnPhe: 0.787 ± 0.017	2.108GlnGly: 2.108 ± 0.029	0.625GlnHis: 0.625 ± 0.018	1.373GlnIle: 1.373 ± 0.023	0.54GlnLys: 0.54 ± 0.016	3.098GlnLeu: 3.098 ± 0.04	0.488GlnMet: 0.488 ± 0.014	0.591GlnAsn: 0.591 ± 0.018	1.813GlnPro: 1.813 ± 0.031	1.061GlnGln: 1.061 ± 0.027	2.375GlnArg: 2.375 ± 0.033	1.348GlnSer: 1.348 ± 0.026	1.512GlnThr: 1.512 ± 0.025	2.706GlnVal: 2.706 ± 0.035	0.512GlnTrp: 0.512 ± 0.015	0.581GlnTyr: 0.581 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	9.31ArgAla: 9.31 ± 0.079	0.592ArgCys: 0.592 ± 0.015	4.405ArgAsp: 4.405 ± 0.044	4.593ArgGlu: 4.593 ± 0.05	2.549ArgPhe: 2.549 ± 0.031	5.549ArgGly: 5.549 ± 0.046	2.033ArgHis: 2.033 ± 0.029	3.374ArgIle: 3.374 ± 0.036	1.622ArgLys: 1.622 ± 0.027	9.185ArgLeu: 9.185 ± 0.084	1.805ArgMet: 1.805 ± 0.029	1.516ArgAsn: 1.516 ± 0.025	4.659ArgPro: 4.659 ± 0.054	2.496ArgGln: 2.496 ± 0.033	7.468ArgArg: 7.468 ± 0.071	3.895ArgSer: 3.895 ± 0.037	4.585ArgThr: 4.585 ± 0.046	6.076ArgVal: 6.076 ± 0.058	1.436ArgTrp: 1.436 ± 0.026	1.877ArgTyr: 1.877 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	6.619SerAla: 6.619 ± 0.055	0.421SerCys: 0.421 ± 0.013	2.6SerAsp: 2.6 ± 0.033	2.271SerGlu: 2.271 ± 0.028	1.643SerPhe: 1.643 ± 0.024	5.954SerGly: 5.954 ± 0.054	1.037SerHis: 1.037 ± 0.021	1.945SerIle: 1.945 ± 0.028	0.914SerLys: 0.914 ± 0.02	4.799SerLeu: 4.799 ± 0.038	1.163SerMet: 1.163 ± 0.023	0.985SerAsn: 0.985 ± 0.023	3.58SerPro: 3.58 ± 0.055	1.284SerGln: 1.284 ± 0.024	3.792SerArg: 3.792 ± 0.04	2.768SerSer: 2.768 ± 0.041	3.072SerThr: 3.072 ± 0.039	4.177SerVal: 4.177 ± 0.043	1.025SerTrp: 1.025 ± 0.019	1.244SerTyr: 1.244 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	7.977ThrAla: 7.977 ± 0.06	0.477ThrCys: 0.477 ± 0.012	3.144ThrAsp: 3.144 ± 0.039	2.987ThrGlu: 2.987 ± 0.032	1.849ThrPhe: 1.849 ± 0.026	6.504ThrGly: 6.504 ± 0.059	1.15ThrHis: 1.15 ± 0.023	2.48ThrIle: 2.48 ± 0.033	1.206ThrLys: 1.206 ± 0.022	6.072ThrLeu: 6.072 ± 0.051	1.114ThrMet: 1.114 ± 0.023	1.177ThrAsn: 1.177 ± 0.029	4.217ThrPro: 4.217 ± 0.053	1.527ThrGln: 1.527 ± 0.026	4.082ThrArg: 4.082 ± 0.035	3.158ThrSer: 3.158 ± 0.041	3.824ThrThr: 3.824 ± 0.052	5.526ThrVal: 5.526 ± 0.055	1.026ThrTrp: 1.026 ± 0.022	1.309ThrTyr: 1.309 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	10.963ValAla: 10.963 ± 0.078	0.651ValCys: 0.651 ± 0.016	4.74ValAsp: 4.74 ± 0.043	4.399ValGlu: 4.399 ± 0.04	2.495ValPhe: 2.495 ± 0.03	6.574ValGly: 6.574 ± 0.06	1.72ValHis: 1.72 ± 0.025	3.599ValIle: 3.599 ± 0.04	1.721ValLys: 1.721 ± 0.026	9.268ValLeu: 9.268 ± 0.075	1.384ValMet: 1.384 ± 0.024	1.882ValAsn: 1.882 ± 0.029	5.018ValPro: 5.018 ± 0.046	2.09ValGln: 2.09 ± 0.029	6.606ValArg: 6.606 ± 0.055	4.485ValSer: 4.485 ± 0.048	5.871ValThr: 5.871 ± 0.048	7.656ValVal: 7.656 ± 0.068	1.122ValTrp: 1.122 ± 0.025	1.633ValTyr: 1.633 ± 0.026	0.0ValXaa: 0.0 ± 0.0
Trp	1.748TrpAla: 1.748 ± 0.029	0.159TrpCys: 0.159 ± 0.008	0.862TrpAsp: 0.862 ± 0.022	0.718TrpGlu: 0.718 ± 0.018	0.551TrpPhe: 0.551 ± 0.015	1.094TrpGly: 1.094 ± 0.022	0.404TrpHis: 0.404 ± 0.012	0.644TrpIle: 0.644 ± 0.015	0.338TrpLys: 0.338 ± 0.012	1.955TrpLeu: 1.955 ± 0.03	0.308TrpMet: 0.308 ± 0.008	0.484TrpAsn: 0.484 ± 0.014	0.934TrpPro: 0.934 ± 0.02	0.627TrpGln: 0.627 ± 0.015	1.465TrpArg: 1.465 ± 0.022	1.02TrpSer: 1.02 ± 0.02	1.099TrpThr: 1.099 ± 0.021	1.017TrpVal: 1.017 ± 0.021	0.383TrpTrp: 0.383 ± 0.013	0.347TrpTyr: 0.347 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.646TyrAla: 2.646 ± 0.036	0.191TyrCys: 0.191 ± 0.008	1.402TyrAsp: 1.402 ± 0.029	1.089TyrGlu: 1.089 ± 0.019	0.678TyrPhe: 0.678 ± 0.017	2.297TyrGly: 2.297 ± 0.034	0.442TyrHis: 0.442 ± 0.013	0.577TyrIle: 0.577 ± 0.016	0.36TyrLys: 0.36 ± 0.012	2.476TyrLeu: 2.476 ± 0.03	0.266TyrMet: 0.266 ± 0.011	0.473TyrAsn: 0.473 ± 0.017	1.191TyrPro: 1.191 ± 0.023	0.79TyrGln: 0.79 ± 0.017	1.902TyrArg: 1.902 ± 0.027	1.02TyrSer: 1.02 ± 0.02	1.208TyrThr: 1.208 ± 0.023	1.728TyrVal: 1.728 ± 0.026	0.392TyrTrp: 0.392 ± 0.012	0.499TyrTyr: 0.499 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8466 proteins (2731098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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