Amino acid dipepetide frequency for Phytophthora parasitica virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.015AlaAla: 3.015 ± 1.409
0.0AlaCys: 0.0 ± 0.0
4.02AlaAsp: 4.02 ± 1.332
3.015AlaGlu: 3.015 ± 2.068
2.01AlaPhe: 2.01 ± 1.079
9.045AlaGly: 9.045 ± 3.066
2.01AlaHis: 2.01 ± 1.088
4.02AlaIle: 4.02 ± 1.756
2.01AlaLys: 2.01 ± 0.396
10.05AlaLeu: 10.05 ± 1.923
1.005AlaMet: 1.005 ± 0.707
3.015AlaAsn: 3.015 ± 1.409
2.01AlaPro: 2.01 ± 1.079
3.015AlaGln: 3.015 ± 0.686
6.03AlaArg: 6.03 ± 2.704
2.01AlaSer: 2.01 ± 1.24
2.01AlaThr: 2.01 ± 1.24
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
3.015AlaTyr: 3.015 ± 0.763
0.0AlaXaa: 0.0 ± 0.0
Cys
1.005CysAla: 1.005 ± 1.071
0.0CysCys: 0.0 ± 0.0
1.005CysAsp: 1.005 ± 0.707
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.005CysLeu: 1.005 ± 0.707
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.005CysGln: 1.005 ± 0.62
0.0CysArg: 0.0 ± 0.0
1.005CysSer: 1.005 ± 0.62
0.0CysThr: 0.0 ± 0.0
1.005CysVal: 1.005 ± 0.62
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.005AspAla: 1.005 ± 0.707
1.005AspCys: 1.005 ± 0.62
9.045AspAsp: 9.045 ± 3.066
5.025AspGlu: 5.025 ± 1.699
4.02AspPhe: 4.02 ± 0.872
3.015AspGly: 3.015 ± 1.86
4.02AspHis: 4.02 ± 1.644
3.015AspIle: 3.015 ± 0.686
4.02AspLys: 4.02 ± 0.739
8.04AspLeu: 8.04 ± 2.356
2.01AspMet: 2.01 ± 0.396
4.02AspAsn: 4.02 ± 1.332
2.01AspPro: 2.01 ± 1.415
3.015AspGln: 3.015 ± 0.964
5.025AspArg: 5.025 ± 0.327
2.01AspSer: 2.01 ± 1.088
2.01AspThr: 2.01 ± 1.24
5.025AspVal: 5.025 ± 1.432
0.0AspTrp: 0.0 ± 0.0
5.025AspTyr: 5.025 ± 1.045
0.0AspXaa: 0.0 ± 0.0
Glu
6.03GluAla: 6.03 ± 3.237
0.0GluCys: 0.0 ± 0.0
6.03GluAsp: 6.03 ± 3.237
5.025GluGlu: 5.025 ± 2.687
3.015GluPhe: 3.015 ± 1.409
2.01GluGly: 2.01 ± 0.396
1.005GluHis: 1.005 ± 0.62
2.01GluIle: 2.01 ± 0.396
6.03GluLys: 6.03 ± 0.818
5.025GluLeu: 5.025 ± 2.826
3.015GluMet: 3.015 ± 2.031
7.035GluAsn: 7.035 ± 2.321
3.015GluPro: 3.015 ± 1.409
1.005GluGln: 1.005 ± 1.071
1.005GluArg: 1.005 ± 0.62
5.025GluSer: 5.025 ± 1.179
2.01GluThr: 2.01 ± 1.24
3.015GluVal: 3.015 ± 0.964
0.0GluTrp: 0.0 ± 0.0
4.02GluTyr: 4.02 ± 0.872
0.0GluXaa: 0.0 ± 0.0
Phe
1.005PheAla: 1.005 ± 0.62
0.0PheCys: 0.0 ± 0.0
1.005PheAsp: 1.005 ± 0.707
2.01PheGlu: 2.01 ± 1.088
2.01PhePhe: 2.01 ± 1.415
1.005PheGly: 1.005 ± 0.62
2.01PheHis: 2.01 ± 1.079
2.01PheIle: 2.01 ± 2.143
3.015PheLys: 3.015 ± 0.964
2.01PheLeu: 2.01 ± 0.396
2.01PheMet: 2.01 ± 1.079
4.02PheAsn: 4.02 ± 1.332
3.015PhePro: 3.015 ± 1.477
2.01PheGln: 2.01 ± 0.396
2.01PheArg: 2.01 ± 1.24
1.005PheSer: 1.005 ± 0.62
2.01PheThr: 2.01 ± 1.415
1.005PheVal: 1.005 ± 0.62
0.0PheTrp: 0.0 ± 0.0
2.01PheTyr: 2.01 ± 0.396
0.0PheXaa: 0.0 ± 0.0
Gly
2.01GlyAla: 2.01 ± 1.24
0.0GlyCys: 0.0 ± 0.0
4.02GlyAsp: 4.02 ± 0.791
8.04GlyGlu: 8.04 ± 2.665
3.015GlyPhe: 3.015 ± 0.686
3.015GlyGly: 3.015 ± 0.686
0.0GlyHis: 0.0 ± 0.0
3.015GlyIle: 3.015 ± 1.86
7.035GlyLys: 7.035 ± 2.081
7.035GlyLeu: 7.035 ± 1.052
1.005GlyMet: 1.005 ± 0.707
5.025GlyAsn: 5.025 ± 1.045
3.015GlyPro: 3.015 ± 1.86
2.01GlyGln: 2.01 ± 1.24
3.015GlyArg: 3.015 ± 1.477
3.015GlySer: 3.015 ± 0.763
5.025GlyThr: 5.025 ± 1.293
4.02GlyVal: 4.02 ± 0.791
1.005GlyTrp: 1.005 ± 0.707
2.01GlyTyr: 2.01 ± 0.396
0.0GlyXaa: 0.0 ± 0.0
His
1.005HisAla: 1.005 ± 1.071
0.0HisCys: 0.0 ± 0.0
2.01HisAsp: 2.01 ± 1.088
1.005HisGlu: 1.005 ± 1.071
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
3.015HisHis: 3.015 ± 2.031
2.01HisIle: 2.01 ± 0.396
0.0HisLys: 0.0 ± 0.0
1.005HisLeu: 1.005 ± 1.071
1.005HisMet: 1.005 ± 0.707
1.005HisAsn: 1.005 ± 1.071
1.005HisPro: 1.005 ± 0.62
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.005HisSer: 1.005 ± 0.707
5.025HisThr: 5.025 ± 2.34
3.015HisVal: 3.015 ± 0.964
1.005HisTrp: 1.005 ± 0.62
2.01HisTyr: 2.01 ± 0.396
0.0HisXaa: 0.0 ± 0.0
Ile
5.025IleAla: 5.025 ± 2.44
1.005IleCys: 1.005 ± 0.707
4.02IleAsp: 4.02 ± 0.739
2.01IleGlu: 2.01 ± 1.079
1.005IlePhe: 1.005 ± 0.62
1.005IleGly: 1.005 ± 0.707
0.0IleHis: 0.0 ± 0.0
1.005IleIle: 1.005 ± 0.707
5.025IleLys: 5.025 ± 2.34
3.015IleLeu: 3.015 ± 1.477
0.0IleMet: 0.0 ± 0.0
6.03IleAsn: 6.03 ± 0.472
2.01IlePro: 2.01 ± 1.415
1.005IleGln: 1.005 ± 0.707
2.01IleArg: 2.01 ± 1.24
3.015IleSer: 3.015 ± 0.964
2.01IleThr: 2.01 ± 1.24
4.02IleVal: 4.02 ± 3.109
1.005IleTrp: 1.005 ± 0.707
1.005IleTyr: 1.005 ± 0.707
0.0IleXaa: 0.0 ± 0.0
Lys
3.015LysAla: 3.015 ± 0.686
1.005LysCys: 1.005 ± 0.62
3.015LysAsp: 3.015 ± 0.763
4.02LysGlu: 4.02 ± 0.872
2.01LysPhe: 2.01 ± 1.415
2.01LysGly: 2.01 ± 1.24
2.01LysHis: 2.01 ± 0.396
2.01LysIle: 2.01 ± 0.396
3.015LysLys: 3.015 ± 0.763
11.055LysLeu: 11.055 ± 1.879
0.0LysMet: 0.0 ± 0.0
3.015LysAsn: 3.015 ± 2.122
2.01LysPro: 2.01 ± 0.396
1.005LysGln: 1.005 ± 0.707
5.025LysArg: 5.025 ± 1.293
4.02LysSer: 4.02 ± 2.829
4.02LysThr: 4.02 ± 2.829
2.01LysVal: 2.01 ± 0.396
0.0LysTrp: 0.0 ± 0.0
4.02LysTyr: 4.02 ± 0.791
0.0LysXaa: 0.0 ± 0.0
Leu
5.025LeuAla: 5.025 ± 1.179
0.0LeuCys: 0.0 ± 0.0
5.025LeuAsp: 5.025 ± 1.045
3.015LeuGlu: 3.015 ± 0.686
2.01LeuPhe: 2.01 ± 0.396
4.02LeuGly: 4.02 ± 0.791
2.01LeuHis: 2.01 ± 2.143
5.025LeuIle: 5.025 ± 1.676
7.035LeuLys: 7.035 ± 3.745
7.035LeuLeu: 7.035 ± 2.601
0.0LeuMet: 0.0 ± 0.0
7.035LeuAsn: 7.035 ± 2.441
7.035LeuPro: 7.035 ± 2.081
5.025LeuGln: 5.025 ± 2.34
8.04LeuArg: 8.04 ± 3.743
2.01LeuSer: 2.01 ± 0.396
8.04LeuThr: 8.04 ± 1.0
8.04LeuVal: 8.04 ± 2.189
2.01LeuTrp: 2.01 ± 1.24
5.025LeuTyr: 5.025 ± 0.327
0.0LeuXaa: 0.0 ± 0.0
Met
3.015MetAla: 3.015 ± 2.031
0.0MetCys: 0.0 ± 0.0
3.015MetAsp: 3.015 ± 2.031
1.005MetGlu: 1.005 ± 1.071
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.01MetIle: 2.01 ± 1.415
0.0MetLys: 0.0 ± 0.0
1.005MetLeu: 1.005 ± 0.707
1.005MetMet: 1.005 ± 1.071
1.005MetAsn: 1.005 ± 0.62
1.005MetPro: 1.005 ± 0.707
2.01MetGln: 2.01 ± 1.088
2.01MetArg: 2.01 ± 1.079
1.005MetSer: 1.005 ± 0.707
0.0MetThr: 0.0 ± 0.0
1.005MetVal: 1.005 ± 0.62
1.005MetTrp: 1.005 ± 0.62
1.005MetTyr: 1.005 ± 0.62
0.0MetXaa: 0.0 ± 0.0
Asn
6.03AsnAla: 6.03 ± 2.819
0.0AsnCys: 0.0 ± 0.0
6.03AsnAsp: 6.03 ± 2.543
4.02AsnGlu: 4.02 ± 0.872
3.015AsnPhe: 3.015 ± 0.763
7.035AsnGly: 7.035 ± 0.237
0.0AsnHis: 0.0 ± 0.0
4.02AsnIle: 4.02 ± 0.739
3.015AsnLys: 3.015 ± 0.686
4.02AsnLeu: 4.02 ± 1.644
2.01AsnMet: 2.01 ± 1.38
4.02AsnAsn: 4.02 ± 0.739
3.015AsnPro: 3.015 ± 1.86
2.01AsnGln: 2.01 ± 0.396
3.015AsnArg: 3.015 ± 2.122
5.025AsnSer: 5.025 ± 1.933
7.035AsnThr: 7.035 ± 2.321
4.02AsnVal: 4.02 ± 1.644
1.005AsnTrp: 1.005 ± 0.62
4.02AsnTyr: 4.02 ± 1.332
0.0AsnXaa: 0.0 ± 0.0
Pro
2.01ProAla: 2.01 ± 1.415
0.0ProCys: 0.0 ± 0.0
2.01ProAsp: 2.01 ± 1.24
4.02ProGlu: 4.02 ± 0.791
1.005ProPhe: 1.005 ± 0.707
6.03ProGly: 6.03 ± 1.525
2.01ProHis: 2.01 ± 1.415
2.01ProIle: 2.01 ± 0.396
1.005ProLys: 1.005 ± 0.707
4.02ProLeu: 4.02 ± 1.332
0.0ProMet: 0.0 ± 0.0
4.02ProAsn: 4.02 ± 1.332
2.01ProPro: 2.01 ± 1.24
1.005ProGln: 1.005 ± 0.707
2.01ProArg: 2.01 ± 1.415
2.01ProSer: 2.01 ± 1.088
4.02ProThr: 4.02 ± 2.049
4.02ProVal: 4.02 ± 1.332
0.0ProTrp: 0.0 ± 0.0
6.03ProTyr: 6.03 ± 1.733
0.0ProXaa: 0.0 ± 0.0
Gln
3.015GlnAla: 3.015 ± 1.409
0.0GlnCys: 0.0 ± 0.0
2.01GlnAsp: 2.01 ± 1.415
3.015GlnGlu: 3.015 ± 2.068
1.005GlnPhe: 1.005 ± 0.707
3.015GlnGly: 3.015 ± 2.122
2.01GlnHis: 2.01 ± 1.088
3.015GlnIle: 3.015 ± 2.122
1.005GlnLys: 1.005 ± 0.707
2.01GlnLeu: 2.01 ± 0.396
1.005GlnMet: 1.005 ± 0.596
1.005GlnAsn: 1.005 ± 0.62
3.015GlnPro: 3.015 ± 0.763
2.01GlnGln: 2.01 ± 1.079
2.01GlnArg: 2.01 ± 0.396
2.01GlnSer: 2.01 ± 1.24
1.005GlnThr: 1.005 ± 0.707
3.015GlnVal: 3.015 ± 0.964
1.005GlnTrp: 1.005 ± 0.707
3.015GlnTyr: 3.015 ± 0.763
0.0GlnXaa: 0.0 ± 0.0
Arg
3.015ArgAla: 3.015 ± 1.409
0.0ArgCys: 0.0 ± 0.0
7.035ArgAsp: 7.035 ± 2.763
3.015ArgGlu: 3.015 ± 0.686
3.015ArgPhe: 3.015 ± 2.122
3.015ArgGly: 3.015 ± 0.763
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
1.005ArgLys: 1.005 ± 0.707
8.04ArgLeu: 8.04 ± 3.834
1.005ArgMet: 1.005 ± 1.071
4.02ArgAsn: 4.02 ± 1.644
1.005ArgPro: 1.005 ± 0.707
2.01ArgGln: 2.01 ± 0.396
4.02ArgArg: 4.02 ± 1.644
1.005ArgSer: 1.005 ± 0.707
3.015ArgThr: 3.015 ± 0.686
5.025ArgVal: 5.025 ± 1.293
2.01ArgTrp: 2.01 ± 1.088
2.01ArgTyr: 2.01 ± 1.24
0.0ArgXaa: 0.0 ± 0.0
Ser
5.025SerAla: 5.025 ± 1.045
1.005SerCys: 1.005 ± 0.62
1.005SerAsp: 1.005 ± 1.071
1.005SerGlu: 1.005 ± 0.707
2.01SerPhe: 2.01 ± 1.088
6.03SerGly: 6.03 ± 2.543
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.02SerLys: 4.02 ± 1.644
3.015SerLeu: 3.015 ± 0.763
0.0SerMet: 0.0 ± 0.0
4.02SerAsn: 4.02 ± 0.791
4.02SerPro: 4.02 ± 0.791
3.015SerGln: 3.015 ± 0.964
1.005SerArg: 1.005 ± 0.62
4.02SerSer: 4.02 ± 0.791
4.02SerThr: 4.02 ± 2.48
4.02SerVal: 4.02 ± 0.739
1.005SerTrp: 1.005 ± 0.707
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.025ThrAla: 5.025 ± 0.327
0.0ThrCys: 0.0 ± 0.0
3.015ThrAsp: 3.015 ± 0.964
3.015ThrGlu: 3.015 ± 2.068
1.005ThrPhe: 1.005 ± 0.62
6.03ThrGly: 6.03 ± 1.525
1.005ThrHis: 1.005 ± 0.707
4.02ThrIle: 4.02 ± 0.791
5.025ThrLys: 5.025 ± 3.537
5.025ThrLeu: 5.025 ± 1.179
3.015ThrMet: 3.015 ± 0.763
6.03ThrAsn: 6.03 ± 2.543
4.02ThrPro: 4.02 ± 0.791
2.01ThrGln: 2.01 ± 1.088
3.015ThrArg: 3.015 ± 0.686
3.015ThrSer: 3.015 ± 0.763
2.01ThrThr: 2.01 ± 1.415
4.02ThrVal: 4.02 ± 0.791
0.0ThrTrp: 0.0 ± 0.0
1.005ThrTyr: 1.005 ± 0.707
0.0ThrXaa: 0.0 ± 0.0
Val
4.02ValAla: 4.02 ± 1.332
0.0ValCys: 0.0 ± 0.0
3.015ValAsp: 3.015 ± 2.122
10.05ValGlu: 10.05 ± 2.358
2.01ValPhe: 2.01 ± 1.24
5.025ValGly: 5.025 ± 1.045
2.01ValHis: 2.01 ± 1.415
5.025ValIle: 5.025 ± 1.432
3.015ValLys: 3.015 ± 0.763
3.015ValLeu: 3.015 ± 2.122
2.01ValMet: 2.01 ± 1.827
3.015ValAsn: 3.015 ± 0.763
3.015ValPro: 3.015 ± 2.122
2.01ValGln: 2.01 ± 0.396
2.01ValArg: 2.01 ± 0.396
4.02ValSer: 4.02 ± 0.791
4.02ValThr: 4.02 ± 0.739
4.02ValVal: 4.02 ± 2.48
0.0ValTrp: 0.0 ± 0.0
2.01ValTyr: 2.01 ± 0.396
0.0ValXaa: 0.0 ± 0.0
Trp
1.005TrpAla: 1.005 ± 1.071
0.0TrpCys: 0.0 ± 0.0
4.02TrpAsp: 4.02 ± 0.791
0.0TrpGlu: 0.0 ± 0.0
1.005TrpPhe: 1.005 ± 0.62
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.005TrpIle: 1.005 ± 0.707
0.0TrpLys: 0.0 ± 0.0
1.005TrpLeu: 1.005 ± 0.707
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.005TrpPro: 1.005 ± 0.62
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.005TrpThr: 1.005 ± 0.62
1.005TrpVal: 1.005 ± 0.62
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.005TyrAla: 1.005 ± 0.62
2.01TyrCys: 2.01 ± 1.079
2.01TyrAsp: 2.01 ± 1.24
3.015TyrGlu: 3.015 ± 2.122
2.01TyrPhe: 2.01 ± 1.088
5.025TyrGly: 5.025 ± 1.293
2.01TyrHis: 2.01 ± 1.24
0.0TyrIle: 0.0 ± 0.0
3.015TyrLys: 3.015 ± 0.763
6.03TyrLeu: 6.03 ± 1.187
0.0TyrMet: 0.0 ± 0.0
6.03TyrAsn: 6.03 ± 0.472
2.01TyrPro: 2.01 ± 0.396
4.02TyrGln: 4.02 ± 1.644
2.01TyrArg: 2.01 ± 1.24
2.01TyrSer: 2.01 ± 1.24
3.015TyrThr: 3.015 ± 0.763
2.01TyrVal: 2.01 ± 1.24
0.0TyrTrp: 0.0 ± 0.0
6.03TyrTyr: 6.03 ± 1.187
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (996 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski