Amino acid dipepetide frequency for Alloprevotella rava F0323

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.078AlaAla: 7.078 ± 0.156	0.921AlaCys: 0.921 ± 0.035	4.581AlaAsp: 4.581 ± 0.08	5.162AlaGlu: 5.162 ± 0.087	3.464AlaPhe: 3.464 ± 0.073	5.206AlaGly: 5.206 ± 0.106	1.511AlaHis: 1.511 ± 0.049	4.65AlaIle: 4.65 ± 0.099	4.353AlaLys: 4.353 ± 0.09	7.556AlaLeu: 7.556 ± 0.125	1.938AlaMet: 1.938 ± 0.058	3.565AlaAsn: 3.565 ± 0.076	2.532AlaPro: 2.532 ± 0.056	3.501AlaGln: 3.501 ± 0.083	3.64AlaArg: 3.64 ± 0.084	4.305AlaSer: 4.305 ± 0.08	4.548AlaThr: 4.548 ± 0.106	4.855AlaVal: 4.855 ± 0.088	0.852AlaTrp: 0.852 ± 0.037	3.091AlaTyr: 3.091 ± 0.075	0.0AlaXaa: 0.0 ± 0.0
Cys	0.82CysAla: 0.82 ± 0.035	0.199CysCys: 0.199 ± 0.017	0.689CysAsp: 0.689 ± 0.036	0.7CysGlu: 0.7 ± 0.03	0.603CysPhe: 0.603 ± 0.027	1.054CysGly: 1.054 ± 0.041	0.333CysHis: 0.333 ± 0.027	0.785CysIle: 0.785 ± 0.032	0.648CysLys: 0.648 ± 0.031	1.091CysLeu: 1.091 ± 0.04	0.259CysMet: 0.259 ± 0.021	0.592CysAsn: 0.592 ± 0.028	0.532CysPro: 0.532 ± 0.028	0.364CysGln: 0.364 ± 0.023	0.697CysArg: 0.697 ± 0.029	0.779CysSer: 0.779 ± 0.036	0.624CysThr: 0.624 ± 0.025	0.809CysVal: 0.809 ± 0.033	0.167CysTrp: 0.167 ± 0.016	0.501CysTyr: 0.501 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	4.293AspAla: 4.293 ± 0.074	0.663AspCys: 0.663 ± 0.029	2.526AspAsp: 2.526 ± 0.053	3.596AspGlu: 3.596 ± 0.075	3.044AspPhe: 3.044 ± 0.063	3.827AspGly: 3.827 ± 0.09	0.953AspHis: 0.953 ± 0.033	3.759AspIle: 3.759 ± 0.075	3.501AspLys: 3.501 ± 0.081	4.646AspLeu: 4.646 ± 0.084	1.415AspMet: 1.415 ± 0.045	2.663AspAsn: 2.663 ± 0.049	1.668AspPro: 1.668 ± 0.046	1.19AspGln: 1.19 ± 0.042	2.51AspArg: 2.51 ± 0.054	3.157AspSer: 3.157 ± 0.085	2.971AspThr: 2.971 ± 0.065	3.493AspVal: 3.493 ± 0.076	0.786AspTrp: 0.786 ± 0.031	2.642AspTyr: 2.642 ± 0.061	0.0AspXaa: 0.0 ± 0.0
Glu	5.154GluAla: 5.154 ± 0.1	0.543GluCys: 0.543 ± 0.029	3.048GluAsp: 3.048 ± 0.068	4.923GluGlu: 4.923 ± 0.112	2.259GluPhe: 2.259 ± 0.063	4.07GluGly: 4.07 ± 0.089	1.299GluHis: 1.299 ± 0.042	4.011GluIle: 4.011 ± 0.102	4.791GluLys: 4.791 ± 0.091	5.898GluLeu: 5.898 ± 0.097	1.994GluMet: 1.994 ± 0.052	3.207GluAsn: 3.207 ± 0.066	1.672GluPro: 1.672 ± 0.052	2.967GluGln: 2.967 ± 0.074	3.588GluArg: 3.588 ± 0.084	2.896GluSer: 2.896 ± 0.066	3.394GluThr: 3.394 ± 0.068	4.032GluVal: 4.032 ± 0.089	0.681GluTrp: 0.681 ± 0.03	2.191GluTyr: 2.191 ± 0.062	0.0GluXaa: 0.0 ± 0.0
Phe	3.284PheAla: 3.284 ± 0.075	0.753PheCys: 0.753 ± 0.035	2.672PheAsp: 2.672 ± 0.064	2.443PheGlu: 2.443 ± 0.058	2.462PhePhe: 2.462 ± 0.075	3.209PheGly: 3.209 ± 0.073	0.984PheHis: 0.984 ± 0.036	2.848PheIle: 2.848 ± 0.067	2.274PheLys: 2.274 ± 0.055	4.239PheLeu: 4.239 ± 0.093	1.187PheMet: 1.187 ± 0.037	2.395PheAsn: 2.395 ± 0.057	1.739PhePro: 1.739 ± 0.053	1.421PheGln: 1.421 ± 0.044	2.409PheArg: 2.409 ± 0.057	3.662PheSer: 3.662 ± 0.079	2.747PheThr: 2.747 ± 0.073	2.899PheVal: 2.899 ± 0.066	0.502PheTrp: 0.502 ± 0.029	1.971PheTyr: 1.971 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	4.623GlyAla: 4.623 ± 0.089	0.831GlyCys: 0.831 ± 0.04	3.187GlyAsp: 3.187 ± 0.062	3.999GlyGlu: 3.999 ± 0.083	3.138GlyPhe: 3.138 ± 0.063	4.68GlyGly: 4.68 ± 0.101	1.436GlyHis: 1.436 ± 0.038	4.821GlyIle: 4.821 ± 0.091	4.758GlyLys: 4.758 ± 0.085	5.98GlyLeu: 5.98 ± 0.094	1.896GlyMet: 1.896 ± 0.053	3.291GlyAsn: 3.291 ± 0.086	1.364GlyPro: 1.364 ± 0.042	2.502GlyGln: 2.502 ± 0.059	3.45GlyArg: 3.45 ± 0.085	3.938GlySer: 3.938 ± 0.08	4.267GlyThr: 4.267 ± 0.091	4.863GlyVal: 4.863 ± 0.092	0.928GlyTrp: 0.928 ± 0.039	2.918GlyTyr: 2.918 ± 0.069	0.0GlyXaa: 0.0 ± 0.0
His	1.391HisAla: 1.391 ± 0.052	0.333HisCys: 0.333 ± 0.022	1.062HisAsp: 1.062 ± 0.043	1.039HisGlu: 1.039 ± 0.039	1.227HisPhe: 1.227 ± 0.051	1.269HisGly: 1.269 ± 0.047	0.549HisHis: 0.549 ± 0.03	1.511HisIle: 1.511 ± 0.047	1.037HisLys: 1.037 ± 0.036	2.128HisLeu: 2.128 ± 0.051	0.341HisMet: 0.341 ± 0.021	1.011HisAsn: 1.011 ± 0.038	1.024HisPro: 1.024 ± 0.041	0.715HisGln: 0.715 ± 0.033	1.179HisArg: 1.179 ± 0.039	1.23HisSer: 1.23 ± 0.042	1.196HisThr: 1.196 ± 0.04	1.156HisVal: 1.156 ± 0.043	0.261HisTrp: 0.261 ± 0.019	0.981HisTyr: 0.981 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	4.964IleAla: 4.964 ± 0.096	0.921IleCys: 0.921 ± 0.039	3.939IleAsp: 3.939 ± 0.071	4.071IleGlu: 4.071 ± 0.085	2.652IlePhe: 2.652 ± 0.065	4.182IleGly: 4.182 ± 0.078	1.284IleHis: 1.284 ± 0.048	4.037IleIle: 4.037 ± 0.101	3.605IleLys: 3.605 ± 0.08	5.479IleLeu: 5.479 ± 0.105	1.419IleMet: 1.419 ± 0.05	3.111IleAsn: 3.111 ± 0.064	3.012IlePro: 3.012 ± 0.07	2.056IleGln: 2.056 ± 0.052	3.146IleArg: 3.146 ± 0.074	4.409IleSer: 4.409 ± 0.076	3.677IleThr: 3.677 ± 0.067	4.402IleVal: 4.402 ± 0.088	0.583IleTrp: 0.583 ± 0.028	2.485IleTyr: 2.485 ± 0.056	0.0IleXaa: 0.0 ± 0.0
Lys	5.109LysAla: 5.109 ± 0.097	0.486LysCys: 0.486 ± 0.029	3.576LysAsp: 3.576 ± 0.071	4.854LysGlu: 4.854 ± 0.096	2.144LysPhe: 2.144 ± 0.056	4.207LysGly: 4.207 ± 0.082	1.177LysHis: 1.177 ± 0.039	3.554LysIle: 3.554 ± 0.074	4.537LysLys: 4.537 ± 0.093	5.154LysLeu: 5.154 ± 0.084	1.98LysMet: 1.98 ± 0.054	3.397LysAsn: 3.397 ± 0.088	2.064LysPro: 2.064 ± 0.059	2.544LysGln: 2.544 ± 0.061	3.083LysArg: 3.083 ± 0.071	3.278LysSer: 3.278 ± 0.069	3.639LysThr: 3.639 ± 0.077	4.106LysVal: 4.106 ± 0.083	0.626LysTrp: 0.626 ± 0.03	2.515LysTyr: 2.515 ± 0.065	0.0LysXaa: 0.0 ± 0.0
Leu	6.67LeuAla: 6.67 ± 0.102	1.436LeuCys: 1.436 ± 0.053	4.553LeuAsp: 4.553 ± 0.069	4.985LeuGlu: 4.985 ± 0.097	4.598LeuPhe: 4.598 ± 0.091	5.831LeuGly: 5.831 ± 0.111	2.155LeuHis: 2.155 ± 0.057	5.172LeuIle: 5.172 ± 0.094	5.798LeuLys: 5.798 ± 0.081	9.632LeuLeu: 9.632 ± 0.166	2.487LeuMet: 2.487 ± 0.066	4.728LeuAsn: 4.728 ± 0.086	4.488LeuPro: 4.488 ± 0.093	4.099LeuGln: 4.099 ± 0.079	5.35LeuArg: 5.35 ± 0.092	7.018LeuSer: 7.018 ± 0.126	5.955LeuThr: 5.955 ± 0.115	5.107LeuVal: 5.107 ± 0.093	1.013LeuTrp: 1.013 ± 0.039	3.482LeuTyr: 3.482 ± 0.071	0.0LeuXaa: 0.0 ± 0.0
Met	2.182MetAla: 2.182 ± 0.061	0.228MetCys: 0.228 ± 0.016	1.354MetAsp: 1.354 ± 0.041	1.63MetGlu: 1.63 ± 0.055	0.901MetPhe: 0.901 ± 0.047	1.847MetGly: 1.847 ± 0.056	0.399MetHis: 0.399 ± 0.025	1.373MetIle: 1.373 ± 0.045	2.208MetLys: 2.208 ± 0.051	2.584MetLeu: 2.584 ± 0.069	0.794MetMet: 0.794 ± 0.041	1.324MetAsn: 1.324 ± 0.043	1.187MetPro: 1.187 ± 0.047	1.106MetGln: 1.106 ± 0.039	1.253MetArg: 1.253 ± 0.047	1.591MetSer: 1.591 ± 0.044	1.504MetThr: 1.504 ± 0.048	1.421MetVal: 1.421 ± 0.039	0.233MetTrp: 0.233 ± 0.02	0.695MetTyr: 0.695 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.841AsnAla: 3.841 ± 0.084	0.58AsnCys: 0.58 ± 0.036	2.375AsnAsp: 2.375 ± 0.058	2.75AsnGlu: 2.75 ± 0.064	2.561AsnPhe: 2.561 ± 0.078	3.797AsnGly: 3.797 ± 0.089	0.951AsnHis: 0.951 ± 0.032	3.58AsnIle: 3.58 ± 0.075	3.064AsnLys: 3.064 ± 0.067	4.437AsnLeu: 4.437 ± 0.084	1.204AsnMet: 1.204 ± 0.038	2.776AsnAsn: 2.776 ± 0.082	2.395AsnPro: 2.395 ± 0.067	1.571AsnGln: 1.571 ± 0.044	2.515AsnArg: 2.515 ± 0.066	2.778AsnSer: 2.778 ± 0.071	2.842AsnThr: 2.842 ± 0.073	3.242AsnVal: 3.242 ± 0.075	0.629AsnTrp: 0.629 ± 0.035	2.189AsnTyr: 2.189 ± 0.061	0.0AsnXaa: 0.0 ± 0.0
Pro	3.056ProAla: 3.056 ± 0.07	0.385ProCys: 0.385 ± 0.021	2.211ProAsp: 2.211 ± 0.061	3.015ProGlu: 3.015 ± 0.064	1.84ProPhe: 1.84 ± 0.051	2.192ProGly: 2.192 ± 0.058	0.838ProHis: 0.838 ± 0.037	2.383ProIle: 2.383 ± 0.052	2.167ProLys: 2.167 ± 0.056	3.434ProLeu: 3.434 ± 0.071	0.912ProMet: 0.912 ± 0.032	1.828ProAsn: 1.828 ± 0.05	0.856ProPro: 0.856 ± 0.036	1.679ProGln: 1.679 ± 0.048	1.497ProArg: 1.497 ± 0.048	2.424ProSer: 2.424 ± 0.059	2.567ProThr: 2.567 ± 0.063	2.476ProVal: 2.476 ± 0.061	0.426ProTrp: 0.426 ± 0.027	1.665ProTyr: 1.665 ± 0.05	0.0ProXaa: 0.0 ± 0.0
Gln	2.924GlnAla: 2.924 ± 0.076	0.34GlnCys: 0.34 ± 0.023	1.609GlnAsp: 1.609 ± 0.049	2.394GlnGlu: 2.394 ± 0.058	1.392GlnPhe: 1.392 ± 0.041	2.312GlnGly: 2.312 ± 0.06	0.808GlnHis: 0.808 ± 0.034	2.371GlnIle: 2.371 ± 0.055	2.678GlnLys: 2.678 ± 0.068	4.228GlnLeu: 4.228 ± 0.069	1.1GlnMet: 1.1 ± 0.038	1.9GlnAsn: 1.9 ± 0.056	1.481GlnPro: 1.481 ± 0.043	2.33GlnGln: 2.33 ± 0.072	2.241GlnArg: 2.241 ± 0.062	2.102GlnSer: 2.102 ± 0.049	2.368GlnThr: 2.368 ± 0.06	2.163GlnVal: 2.163 ± 0.056	0.439GlnTrp: 0.439 ± 0.025	1.414GlnTyr: 1.414 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	3.4ArgAla: 3.4 ± 0.081	0.536ArgCys: 0.536 ± 0.028	2.424ArgAsp: 2.424 ± 0.059	3.311ArgGlu: 3.311 ± 0.084	2.386ArgPhe: 2.386 ± 0.059	2.915ArgGly: 2.915 ± 0.069	1.207ArgHis: 1.207 ± 0.043	3.579ArgIle: 3.579 ± 0.071	3.378ArgLys: 3.378 ± 0.071	5.176ArgLeu: 5.176 ± 0.101	1.503ArgMet: 1.503 ± 0.047	2.592ArgAsn: 2.592 ± 0.066	1.976ArgPro: 1.976 ± 0.053	2.176ArgGln: 2.176 ± 0.057	2.917ArgArg: 2.917 ± 0.073	2.812ArgSer: 2.812 ± 0.07	2.894ArgThr: 2.894 ± 0.065	2.97ArgVal: 2.97 ± 0.062	0.685ArgTrp: 0.685 ± 0.032	2.218ArgTyr: 2.218 ± 0.061	0.0ArgXaa: 0.0 ± 0.0
Ser	4.613SerAla: 4.613 ± 0.071	0.781SerCys: 0.781 ± 0.039	3.222SerAsp: 3.222 ± 0.064	3.356SerGlu: 3.356 ± 0.067	3.258SerPhe: 3.258 ± 0.077	4.183SerGly: 4.183 ± 0.079	1.286SerHis: 1.286 ± 0.044	4.235SerIle: 4.235 ± 0.091	3.284SerLys: 3.284 ± 0.071	6.251SerLeu: 6.251 ± 0.11	1.413SerMet: 1.413 ± 0.049	2.951SerAsn: 2.951 ± 0.077	2.303SerPro: 2.303 ± 0.062	2.218SerGln: 2.218 ± 0.055	2.866SerArg: 2.866 ± 0.053	4.121SerSer: 4.121 ± 0.099	3.655SerThr: 3.655 ± 0.072	4.278SerVal: 4.278 ± 0.079	0.71SerTrp: 0.71 ± 0.032	2.573SerTyr: 2.573 ± 0.073	0.001SerXaa: 0.001 ± 0.001
Thr	5.049ThrAla: 5.049 ± 0.104	0.58ThrCys: 0.58 ± 0.031	3.549ThrAsp: 3.549 ± 0.065	3.528ThrGlu: 3.528 ± 0.073	2.922ThrPhe: 2.922 ± 0.078	4.126ThrGly: 4.126 ± 0.082	1.095ThrHis: 1.095 ± 0.034	3.984ThrIle: 3.984 ± 0.08	3.057ThrLys: 3.057 ± 0.076	5.975ThrLeu: 5.975 ± 0.098	1.237ThrMet: 1.237 ± 0.045	2.634ThrAsn: 2.634 ± 0.07	3.061ThrPro: 3.061 ± 0.065	2.065ThrGln: 2.065 ± 0.059	2.425ThrArg: 2.425 ± 0.06	3.613ThrSer: 3.613 ± 0.086	4.026ThrThr: 4.026 ± 0.095	3.767ThrVal: 3.767 ± 0.078	0.665ThrTrp: 0.665 ± 0.03	2.36ThrTyr: 2.36 ± 0.062	0.0ThrXaa: 0.0 ± 0.0
Val	4.961ValAla: 4.961 ± 0.097	1.015ValCys: 1.015 ± 0.043	3.667ValAsp: 3.667 ± 0.072	3.987ValGlu: 3.987 ± 0.077	2.817ValPhe: 2.817 ± 0.073	4.381ValGly: 4.381 ± 0.089	1.181ValHis: 1.181 ± 0.043	3.591ValIle: 3.591 ± 0.076	3.786ValLys: 3.786 ± 0.077	5.79ValLeu: 5.79 ± 0.101	1.441ValMet: 1.441 ± 0.048	3.179ValAsn: 3.179 ± 0.069	2.551ValPro: 2.551 ± 0.055	2.135ValGln: 2.135 ± 0.05	3.501ValArg: 3.501 ± 0.078	4.361ValSer: 4.361 ± 0.079	3.721ValThr: 3.721 ± 0.082	4.806ValVal: 4.806 ± 0.093	0.715ValTrp: 0.715 ± 0.033	2.404ValTyr: 2.404 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	0.796TrpAla: 0.796 ± 0.035	0.156TrpCys: 0.156 ± 0.016	0.655TrpAsp: 0.655 ± 0.033	0.654TrpGlu: 0.654 ± 0.033	0.495TrpPhe: 0.495 ± 0.025	0.835TrpGly: 0.835 ± 0.04	0.277TrpHis: 0.277 ± 0.019	0.672TrpIle: 0.672 ± 0.029	0.809TrpLys: 0.809 ± 0.037	1.123TrpLeu: 1.123 ± 0.04	0.393TrpMet: 0.393 ± 0.026	0.672TrpAsn: 0.672 ± 0.027	0.31TrpPro: 0.31 ± 0.022	0.564TrpGln: 0.564 ± 0.027	0.598TrpArg: 0.598 ± 0.033	0.61TrpSer: 0.61 ± 0.034	0.718TrpThr: 0.718 ± 0.037	0.666TrpVal: 0.666 ± 0.037	0.157TrpTrp: 0.157 ± 0.014	0.431TrpTyr: 0.431 ± 0.029	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.102TyrAla: 3.102 ± 0.07	0.56TyrCys: 0.56 ± 0.026	2.404TyrAsp: 2.404 ± 0.06	2.222TyrGlu: 2.222 ± 0.054	1.939TyrPhe: 1.939 ± 0.052	2.745TyrGly: 2.745 ± 0.065	0.919TyrHis: 0.919 ± 0.033	2.518TyrIle: 2.518 ± 0.062	2.296TyrLys: 2.296 ± 0.063	3.756TyrLeu: 3.756 ± 0.07	0.898TyrMet: 0.898 ± 0.042	2.262TyrAsn: 2.262 ± 0.067	1.636TyrPro: 1.636 ± 0.041	1.394TyrGln: 1.394 ± 0.04	2.184TyrArg: 2.184 ± 0.051	2.475TyrSer: 2.475 ± 0.061	2.406TyrThr: 2.406 ± 0.07	2.48TyrVal: 2.48 ± 0.054	0.532TyrTrp: 0.532 ± 0.026	1.916TyrTyr: 1.916 ± 0.055	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2009 proteins (732668 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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