Amino acid dipepetide frequency for Halomonas beimenensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.06AlaAla: 14.06 ± 0.149	1.35AlaCys: 1.35 ± 0.035	6.422AlaAsp: 6.422 ± 0.075	8.947AlaGlu: 8.947 ± 0.105	4.244AlaPhe: 4.244 ± 0.074	10.816AlaGly: 10.816 ± 0.124	2.522AlaHis: 2.522 ± 0.05	5.177AlaIle: 5.177 ± 0.073	2.275AlaLys: 2.275 ± 0.052	15.256AlaLeu: 15.256 ± 0.176	3.468AlaMet: 3.468 ± 0.06	2.209AlaAsn: 2.209 ± 0.047	5.925AlaPro: 5.925 ± 0.081	3.541AlaGln: 3.541 ± 0.054	10.134AlaArg: 10.134 ± 0.119	5.986AlaSer: 5.986 ± 0.072	5.405AlaThr: 5.405 ± 0.066	8.001AlaVal: 8.001 ± 0.091	2.19AlaTrp: 2.19 ± 0.053	2.422AlaTyr: 2.422 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.025	0.109CysCys: 0.109 ± 0.009	0.576CysAsp: 0.576 ± 0.023	0.523CysGlu: 0.523 ± 0.021	0.34CysPhe: 0.34 ± 0.016	0.987CysGly: 0.987 ± 0.03	0.353CysHis: 0.353 ± 0.018	0.319CysIle: 0.319 ± 0.017	0.182CysLys: 0.182 ± 0.011	1.101CysLeu: 1.101 ± 0.033	0.178CysMet: 0.178 ± 0.013	0.202CysAsn: 0.202 ± 0.014	0.577CysPro: 0.577 ± 0.026	0.329CysGln: 0.329 ± 0.018	0.955CysArg: 0.955 ± 0.034	0.431CysSer: 0.431 ± 0.021	0.382CysThr: 0.382 ± 0.02	0.602CysVal: 0.602 ± 0.025	0.136CysTrp: 0.136 ± 0.012	0.25CysTyr: 0.25 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.167AspAla: 7.167 ± 0.084	0.528AspCys: 0.528 ± 0.023	3.889AspAsp: 3.889 ± 0.074	4.175AspGlu: 4.175 ± 0.058	2.203AspPhe: 2.203 ± 0.044	5.158AspGly: 5.158 ± 0.076	1.546AspHis: 1.546 ± 0.041	2.555AspIle: 2.555 ± 0.046	1.329AspLys: 1.329 ± 0.037	5.979AspLeu: 5.979 ± 0.081	1.228AspMet: 1.228 ± 0.031	1.244AspAsn: 1.244 ± 0.033	3.404AspPro: 3.404 ± 0.058	1.885AspGln: 1.885 ± 0.035	4.523AspArg: 4.523 ± 0.069	2.246AspSer: 2.246 ± 0.051	2.722AspThr: 2.722 ± 0.046	3.658AspVal: 3.658 ± 0.061	1.183AspTrp: 1.183 ± 0.037	1.764AspTyr: 1.764 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	10.556GluAla: 10.556 ± 0.14	0.461GluCys: 0.461 ± 0.021	3.541GluAsp: 3.541 ± 0.055	4.259GluGlu: 4.259 ± 0.066	1.51GluPhe: 1.51 ± 0.039	5.699GluGly: 5.699 ± 0.076	1.775GluHis: 1.775 ± 0.049	2.904GluIle: 2.904 ± 0.048	1.482GluLys: 1.482 ± 0.037	7.148GluLeu: 7.148 ± 0.098	1.389GluMet: 1.389 ± 0.034	1.197GluAsn: 1.197 ± 0.031	3.186GluPro: 3.186 ± 0.081	2.636GluGln: 2.636 ± 0.054	6.905GluArg: 6.905 ± 0.085	2.689GluSer: 2.689 ± 0.049	3.499GluThr: 3.499 ± 0.054	5.156GluVal: 5.156 ± 0.066	0.827GluTrp: 0.827 ± 0.03	1.082GluTyr: 1.082 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.831PheAla: 3.831 ± 0.06	0.362PheCys: 0.362 ± 0.018	2.414PheAsp: 2.414 ± 0.051	2.133PheGlu: 2.133 ± 0.042	1.279PhePhe: 1.279 ± 0.04	3.163PheGly: 3.163 ± 0.055	0.82PheHis: 0.82 ± 0.025	1.397PheIle: 1.397 ± 0.04	0.755PheLys: 0.755 ± 0.029	3.364PheLeu: 3.364 ± 0.058	0.793PheMet: 0.793 ± 0.029	0.867PheAsn: 0.867 ± 0.027	1.475PhePro: 1.475 ± 0.034	1.065PheGln: 1.065 ± 0.033	2.235PheArg: 2.235 ± 0.051	1.818PheSer: 1.818 ± 0.041	1.781PheThr: 1.781 ± 0.042	2.441PheVal: 2.441 ± 0.05	0.479PheTrp: 0.479 ± 0.022	0.885PheTyr: 0.885 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	8.229GlyAla: 8.229 ± 0.108	0.97GlyCys: 0.97 ± 0.031	4.731GlyAsp: 4.731 ± 0.079	6.825GlyGlu: 6.825 ± 0.085	3.22GlyPhe: 3.22 ± 0.045	7.41GlyGly: 7.41 ± 0.12	2.346GlyHis: 2.346 ± 0.041	4.26GlyIle: 4.26 ± 0.066	2.346GlyLys: 2.346 ± 0.043	10.374GlyLeu: 10.374 ± 0.101	2.443GlyMet: 2.443 ± 0.057	1.87GlyAsn: 1.87 ± 0.052	3.312GlyPro: 3.312 ± 0.057	3.036GlyGln: 3.036 ± 0.047	7.036GlyArg: 7.036 ± 0.098	3.976GlySer: 3.976 ± 0.058	3.851GlyThr: 3.851 ± 0.059	6.645GlyVal: 6.645 ± 0.088	1.543GlyTrp: 1.543 ± 0.036	2.324GlyTyr: 2.324 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.66HisAla: 2.66 ± 0.043	0.329HisCys: 0.329 ± 0.016	1.604HisAsp: 1.604 ± 0.037	1.413HisGlu: 1.413 ± 0.034	1.027HisPhe: 1.027 ± 0.03	2.425HisGly: 2.425 ± 0.051	0.866HisHis: 0.866 ± 0.026	0.796HisIle: 0.796 ± 0.027	0.496HisLys: 0.496 ± 0.02	2.845HisLeu: 2.845 ± 0.052	0.433HisMet: 0.433 ± 0.021	0.514HisAsn: 0.514 ± 0.024	1.793HisPro: 1.793 ± 0.043	0.88HisGln: 0.88 ± 0.027	2.284HisArg: 2.284 ± 0.055	1.013HisSer: 1.013 ± 0.027	0.907HisThr: 0.907 ± 0.027	1.492HisVal: 1.492 ± 0.038	0.465HisTrp: 0.465 ± 0.022	0.773HisTyr: 0.773 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.355IleAla: 5.355 ± 0.069	0.369IleCys: 0.369 ± 0.019	3.127IleAsp: 3.127 ± 0.06	3.148IleGlu: 3.148 ± 0.06	1.267IlePhe: 1.267 ± 0.04	4.092IleGly: 4.092 ± 0.074	0.99IleHis: 0.99 ± 0.034	1.563IleIle: 1.563 ± 0.044	1.001IleLys: 1.001 ± 0.036	3.84IleLeu: 3.84 ± 0.061	0.789IleMet: 0.789 ± 0.027	1.199IleAsn: 1.199 ± 0.033	2.078IlePro: 2.078 ± 0.048	1.279IleGln: 1.279 ± 0.033	3.107IleArg: 3.107 ± 0.049	2.034IleSer: 2.034 ± 0.045	2.277IleThr: 2.277 ± 0.048	2.905IleVal: 2.905 ± 0.055	0.394IleTrp: 0.394 ± 0.019	0.796IleTyr: 0.796 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.895LysAla: 2.895 ± 0.057	0.145LysCys: 0.145 ± 0.011	1.127LysAsp: 1.127 ± 0.034	1.207LysGlu: 1.207 ± 0.039	0.533LysPhe: 0.533 ± 0.022	1.921LysGly: 1.921 ± 0.04	0.496LysHis: 0.496 ± 0.022	0.863LysIle: 0.863 ± 0.028	0.751LysLys: 0.751 ± 0.027	2.27LysLeu: 2.27 ± 0.052	0.468LysMet: 0.468 ± 0.021	0.468LysAsn: 0.468 ± 0.022	1.321LysPro: 1.321 ± 0.046	0.815LysGln: 0.815 ± 0.029	2.062LysArg: 2.062 ± 0.046	1.117LysSer: 1.117 ± 0.032	1.181LysThr: 1.181 ± 0.033	1.824LysVal: 1.824 ± 0.045	0.252LysTrp: 0.252 ± 0.015	0.421LysTyr: 0.421 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	17.133LeuAla: 17.133 ± 0.18	1.141LeuCys: 1.141 ± 0.033	7.72LeuAsp: 7.72 ± 0.099	8.342LeuGlu: 8.342 ± 0.102	3.526LeuPhe: 3.526 ± 0.065	10.314LeuGly: 10.314 ± 0.133	2.52LeuHis: 2.52 ± 0.05	4.839LeuIle: 4.839 ± 0.073	2.779LeuLys: 2.779 ± 0.051	12.265LeuLeu: 12.265 ± 0.171	2.73LeuMet: 2.73 ± 0.052	2.366LeuAsn: 2.366 ± 0.046	6.683LeuPro: 6.683 ± 0.088	3.093LeuGln: 3.093 ± 0.054	7.581LeuArg: 7.581 ± 0.088	6.078LeuSer: 6.078 ± 0.077	5.929LeuThr: 5.929 ± 0.069	8.947LeuVal: 8.947 ± 0.11	1.563LeuTrp: 1.563 ± 0.046	2.26LeuTyr: 2.26 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.1MetAla: 3.1 ± 0.057	0.159MetCys: 0.159 ± 0.011	1.095MetAsp: 1.095 ± 0.035	1.105MetGlu: 1.105 ± 0.031	0.593MetPhe: 0.593 ± 0.023	1.84MetGly: 1.84 ± 0.047	0.499MetHis: 0.499 ± 0.02	1.095MetIle: 1.095 ± 0.034	0.731MetLys: 0.731 ± 0.028	2.536MetLeu: 2.536 ± 0.044	0.609MetMet: 0.609 ± 0.025	0.67MetAsn: 0.67 ± 0.024	1.408MetPro: 1.408 ± 0.032	0.781MetGln: 0.781 ± 0.028	1.71MetArg: 1.71 ± 0.037	1.634MetSer: 1.634 ± 0.031	1.762MetThr: 1.762 ± 0.039	1.658MetVal: 1.658 ± 0.041	0.186MetTrp: 0.186 ± 0.011	0.312MetTyr: 0.312 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.489AsnAla: 2.489 ± 0.05	0.198AsnCys: 0.198 ± 0.014	1.19AsnAsp: 1.19 ± 0.03	1.089AsnGlu: 1.089 ± 0.034	0.691AsnPhe: 0.691 ± 0.027	1.755AsnGly: 1.755 ± 0.046	0.499AsnHis: 0.499 ± 0.02	0.971AsnIle: 0.971 ± 0.033	0.453AsnLys: 0.453 ± 0.019	2.484AsnLeu: 2.484 ± 0.048	0.448AsnMet: 0.448 ± 0.023	0.524AsnAsn: 0.524 ± 0.023	1.484AsnPro: 1.484 ± 0.035	0.714AsnGln: 0.714 ± 0.026	1.705AsnArg: 1.705 ± 0.043	0.787AsnSer: 0.787 ± 0.029	0.942AsnThr: 0.942 ± 0.033	1.528AsnVal: 1.528 ± 0.04	0.297AsnTrp: 0.297 ± 0.015	0.502AsnTyr: 0.502 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.32ProAla: 6.32 ± 0.071	0.396ProCys: 0.396 ± 0.021	3.638ProAsp: 3.638 ± 0.054	4.639ProGlu: 4.639 ± 0.073	1.757ProPhe: 1.757 ± 0.04	5.014ProGly: 5.014 ± 0.064	1.235ProHis: 1.235 ± 0.034	1.776ProIle: 1.776 ± 0.041	1.0ProLys: 1.0 ± 0.041	6.082ProLeu: 6.082 ± 0.079	1.297ProMet: 1.297 ± 0.028	0.968ProAsn: 0.968 ± 0.026	2.725ProPro: 2.725 ± 0.059	1.503ProGln: 1.503 ± 0.033	3.981ProArg: 3.981 ± 0.065	2.605ProSer: 2.605 ± 0.045	2.227ProThr: 2.227 ± 0.048	4.106ProVal: 4.106 ± 0.051	0.917ProTrp: 0.917 ± 0.025	1.074ProTyr: 1.074 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	5.362GlnAla: 5.362 ± 0.078	0.274GlnCys: 0.274 ± 0.016	1.707GlnAsp: 1.707 ± 0.042	1.897GlnGlu: 1.897 ± 0.04	0.843GlnPhe: 0.843 ± 0.027	3.222GlnGly: 3.222 ± 0.055	0.761GlnHis: 0.761 ± 0.024	1.155GlnIle: 1.155 ± 0.031	0.725GlnLys: 0.725 ± 0.027	3.413GlnLeu: 3.413 ± 0.062	0.625GlnMet: 0.625 ± 0.023	0.587GlnAsn: 0.587 ± 0.024	1.673GlnPro: 1.673 ± 0.044	1.507GlnGln: 1.507 ± 0.043	3.034GlnArg: 3.034 ± 0.051	1.422GlnSer: 1.422 ± 0.036	1.329GlnThr: 1.329 ± 0.035	2.565GlnVal: 2.565 ± 0.047	0.486GlnTrp: 0.486 ± 0.022	0.625GlnTyr: 0.625 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.919ArgAla: 7.919 ± 0.1	0.692ArgCys: 0.692 ± 0.03	4.795ArgAsp: 4.795 ± 0.077	6.097ArgGlu: 6.097 ± 0.079	3.173ArgPhe: 3.173 ± 0.051	5.48ArgGly: 5.48 ± 0.082	2.813ArgHis: 2.813 ± 0.049	3.318ArgIle: 3.318 ± 0.056	1.579ArgLys: 1.579 ± 0.043	12.375ArgLeu: 12.375 ± 0.167	1.706ArgMet: 1.706 ± 0.042	1.408ArgAsn: 1.408 ± 0.036	3.98ArgPro: 3.98 ± 0.064	3.403ArgGln: 3.403 ± 0.061	8.254ArgArg: 8.254 ± 0.121	3.027ArgSer: 3.027 ± 0.051	2.964ArgThr: 2.964 ± 0.048	5.864ArgVal: 5.864 ± 0.067	1.266ArgTrp: 1.266 ± 0.034	2.141ArgTyr: 2.141 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.864SerAla: 4.864 ± 0.069	0.392SerCys: 0.392 ± 0.019	2.338SerAsp: 2.338 ± 0.043	2.539SerGlu: 2.539 ± 0.057	1.619SerPhe: 1.619 ± 0.038	4.491SerGly: 4.491 ± 0.071	1.169SerHis: 1.169 ± 0.031	1.884SerIle: 1.884 ± 0.043	0.894SerLys: 0.894 ± 0.028	6.285SerLeu: 6.285 ± 0.087	1.16SerMet: 1.16 ± 0.031	0.966SerAsn: 0.966 ± 0.032	2.972SerPro: 2.972 ± 0.051	1.576SerGln: 1.576 ± 0.037	4.335SerArg: 4.335 ± 0.052	2.323SerSer: 2.323 ± 0.052	2.205SerThr: 2.205 ± 0.044	3.327SerVal: 3.327 ± 0.057	0.631SerTrp: 0.631 ± 0.025	1.003SerTyr: 1.003 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.106ThrAla: 5.106 ± 0.063	0.425ThrCys: 0.425 ± 0.02	2.336ThrAsp: 2.336 ± 0.054	2.561ThrGlu: 2.561 ± 0.053	1.697ThrPhe: 1.697 ± 0.042	4.423ThrGly: 4.423 ± 0.068	1.079ThrHis: 1.079 ± 0.033	1.777ThrIle: 1.777 ± 0.039	0.765ThrLys: 0.765 ± 0.026	7.089ThrLeu: 7.089 ± 0.092	0.898ThrMet: 0.898 ± 0.024	0.952ThrAsn: 0.952 ± 0.028	3.516ThrPro: 3.516 ± 0.058	1.416ThrGln: 1.416 ± 0.035	3.861ThrArg: 3.861 ± 0.059	2.23ThrSer: 2.23 ± 0.052	2.468ThrThr: 2.468 ± 0.05	3.397ThrVal: 3.397 ± 0.062	0.653ThrTrp: 0.653 ± 0.023	0.981ThrTyr: 0.981 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	8.726ValAla: 8.726 ± 0.089	0.721ValCys: 0.721 ± 0.025	4.279ValAsp: 4.279 ± 0.068	5.175ValGlu: 5.175 ± 0.076	2.546ValPhe: 2.546 ± 0.053	5.618ValGly: 5.618 ± 0.074	1.614ValHis: 1.614 ± 0.038	3.698ValIle: 3.698 ± 0.07	1.806ValLys: 1.806 ± 0.044	7.781ValLeu: 7.781 ± 0.09	2.036ValMet: 2.036 ± 0.048	1.747ValAsn: 1.747 ± 0.038	3.739ValPro: 3.739 ± 0.057	2.046ValGln: 2.046 ± 0.043	4.8ValArg: 4.8 ± 0.065	3.785ValSer: 3.785 ± 0.047	4.119ValThr: 4.119 ± 0.061	5.976ValVal: 5.976 ± 0.09	0.873ValTrp: 0.873 ± 0.027	1.51ValTyr: 1.51 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.283TrpAla: 1.283 ± 0.037	0.183TrpCys: 0.183 ± 0.011	0.592TrpAsp: 0.592 ± 0.023	0.717TrpGlu: 0.717 ± 0.027	0.473TrpPhe: 0.473 ± 0.021	0.969TrpGly: 0.969 ± 0.028	0.455TrpHis: 0.455 ± 0.019	0.554TrpIle: 0.554 ± 0.021	0.364TrpLys: 0.364 ± 0.02	2.518TrpLeu: 2.518 ± 0.064	0.384TrpMet: 0.384 ± 0.016	0.329TrpAsn: 0.329 ± 0.017	0.803TrpPro: 0.803 ± 0.031	0.844TrpGln: 0.844 ± 0.031	1.481TrpArg: 1.481 ± 0.044	0.753TrpSer: 0.753 ± 0.026	0.654TrpThr: 0.654 ± 0.025	1.015TrpVal: 1.015 ± 0.026	0.323TrpTrp: 0.323 ± 0.019	0.312TrpTyr: 0.312 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.356TyrAla: 2.356 ± 0.045	0.269TyrCys: 0.269 ± 0.016	1.267TyrAsp: 1.267 ± 0.033	1.11TyrGlu: 1.11 ± 0.033	0.816TyrPhe: 0.816 ± 0.03	1.949TyrGly: 1.949 ± 0.045	0.658TyrHis: 0.658 ± 0.023	0.709TyrIle: 0.709 ± 0.027	0.425TyrLys: 0.425 ± 0.019	2.804TyrLeu: 2.804 ± 0.052	0.399TyrMet: 0.399 ± 0.021	0.462TyrAsn: 0.462 ± 0.022	1.206TyrPro: 1.206 ± 0.033	0.864TyrGln: 0.864 ± 0.028	2.271TyrArg: 2.271 ± 0.044	1.019TyrSer: 1.019 ± 0.031	1.025TyrThr: 1.025 ± 0.03	1.486TyrVal: 1.486 ± 0.037	0.341TyrTrp: 0.341 ± 0.018	0.613TyrTyr: 0.613 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3771 proteins (1196699 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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