Amino acid dipepetide frequency for Beihai sobemo-like virus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.9AlaAla: 1.9 ± 0.075
0.633AlaCys: 0.633 ± 0.777
3.8AlaAsp: 3.8 ± 1.277
3.167AlaGlu: 3.167 ± 1.755
3.167AlaPhe: 3.167 ± 0.627
2.533AlaGly: 2.533 ± 1.404
1.267AlaHis: 1.267 ± 0.426
3.167AlaIle: 3.167 ± 1.628
5.066AlaLys: 5.066 ± 1.681
9.5AlaLeu: 9.5 ± 0.755
3.167AlaMet: 3.167 ± 1.379
2.533AlaAsn: 2.533 ± 0.851
1.267AlaPro: 1.267 ± 1.553
2.533AlaGln: 2.533 ± 0.276
4.433AlaArg: 4.433 ± 1.33
3.167AlaSer: 3.167 ± 0.5
2.533AlaThr: 2.533 ± 1.404
3.8AlaVal: 3.8 ± 1.277
0.0AlaTrp: 0.0 ± 0.0
1.9AlaTyr: 1.9 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
1.267CysAla: 1.267 ± 0.426
0.633CysCys: 0.633 ± 0.351
1.267CysAsp: 1.267 ± 0.702
1.267CysGlu: 1.267 ± 0.426
0.633CysPhe: 0.633 ± 0.351
1.267CysGly: 1.267 ± 0.426
0.633CysHis: 0.633 ± 0.777
1.267CysIle: 1.267 ± 0.426
0.633CysLys: 0.633 ± 0.351
1.267CysLeu: 1.267 ± 0.426
2.533CysMet: 2.533 ± 0.276
1.9CysAsn: 1.9 ± 1.202
2.533CysPro: 2.533 ± 0.276
1.9CysGln: 1.9 ± 1.053
0.633CysArg: 0.633 ± 0.351
2.533CysSer: 2.533 ± 0.276
0.0CysThr: 0.0 ± 0.0
0.633CysVal: 0.633 ± 0.351
0.0CysTrp: 0.0 ± 0.0
1.267CysTyr: 1.267 ± 1.553
0.0CysXaa: 0.0 ± 0.0
Asp
3.167AspAla: 3.167 ± 0.5
1.9AspCys: 1.9 ± 0.075
5.066AspAsp: 5.066 ± 0.553
6.966AspGlu: 6.966 ± 1.606
3.167AspPhe: 3.167 ± 1.755
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
3.8AspIle: 3.8 ± 0.978
2.533AspLys: 2.533 ± 0.851
0.633AspLeu: 0.633 ± 0.351
0.0AspMet: 0.0 ± 0.0
1.9AspAsn: 1.9 ± 1.053
5.7AspPro: 5.7 ± 0.904
3.167AspGln: 3.167 ± 0.5
4.433AspArg: 4.433 ± 0.926
4.433AspSer: 4.433 ± 1.33
2.533AspThr: 2.533 ± 0.851
5.7AspVal: 5.7 ± 2.479
1.267AspTrp: 1.267 ± 0.426
5.066AspTyr: 5.066 ± 0.575
0.0AspXaa: 0.0 ± 0.0
Glu
5.7GluAla: 5.7 ± 0.904
3.167GluCys: 3.167 ± 0.627
6.333GluAsp: 6.333 ± 0.127
3.8GluGlu: 3.8 ± 2.106
3.8GluPhe: 3.8 ± 1.277
2.533GluGly: 2.533 ± 0.276
0.0GluHis: 0.0 ± 0.0
1.9GluIle: 1.9 ± 0.075
4.433GluLys: 4.433 ± 2.054
3.8GluLeu: 3.8 ± 0.978
0.633GluMet: 0.633 ± 0.351
3.167GluAsn: 3.167 ± 0.627
1.9GluPro: 1.9 ± 0.075
1.267GluGln: 1.267 ± 0.702
1.267GluArg: 1.267 ± 0.426
5.7GluSer: 5.7 ± 0.904
0.0GluThr: 0.0 ± 0.0
5.7GluVal: 5.7 ± 0.904
0.633GluTrp: 0.633 ± 0.351
1.267GluTyr: 1.267 ± 0.426
0.0GluXaa: 0.0 ± 0.0
Phe
1.9PheAla: 1.9 ± 1.053
1.267PheCys: 1.267 ± 1.553
4.433PheAsp: 4.433 ± 0.202
3.167PheGlu: 3.167 ± 0.5
1.267PhePhe: 1.267 ± 0.702
3.167PheGly: 3.167 ± 1.628
1.267PheHis: 1.267 ± 0.702
4.433PheIle: 4.433 ± 0.926
0.0PheLys: 0.0 ± 0.0
3.8PheLeu: 3.8 ± 0.149
0.633PheMet: 0.633 ± 0.777
0.633PheAsn: 0.633 ± 0.777
1.9PhePro: 1.9 ± 0.075
3.8PheGln: 3.8 ± 0.978
2.533PheArg: 2.533 ± 0.851
3.167PheSer: 3.167 ± 0.627
0.633PheThr: 0.633 ± 0.777
2.533PheVal: 2.533 ± 0.276
0.633PheTrp: 0.633 ± 0.777
1.267PheTyr: 1.267 ± 0.426
0.0PheXaa: 0.0 ± 0.0
Gly
3.8GlyAla: 3.8 ± 1.277
0.633GlyCys: 0.633 ± 0.351
2.533GlyAsp: 2.533 ± 0.851
3.167GlyGlu: 3.167 ± 2.756
2.533GlyPhe: 2.533 ± 0.851
3.8GlyGly: 3.8 ± 0.149
1.267GlyHis: 1.267 ± 1.553
2.533GlyIle: 2.533 ± 0.276
5.066GlyLys: 5.066 ± 1.681
3.167GlyLeu: 3.167 ± 1.755
1.267GlyMet: 1.267 ± 0.702
1.267GlyAsn: 1.267 ± 0.702
0.633GlyPro: 0.633 ± 0.351
1.9GlyGln: 1.9 ± 1.053
3.167GlyArg: 3.167 ± 1.755
6.333GlySer: 6.333 ± 1.255
3.167GlyThr: 3.167 ± 0.5
3.8GlyVal: 3.8 ± 2.405
3.167GlyTrp: 3.167 ± 1.628
1.267GlyTyr: 1.267 ± 0.702
0.0GlyXaa: 0.0 ± 0.0
His
0.633HisAla: 0.633 ± 0.777
0.0HisCys: 0.0 ± 0.0
1.267HisAsp: 1.267 ± 0.702
1.9HisGlu: 1.9 ± 0.075
0.0HisPhe: 0.0 ± 0.0
0.633HisGly: 0.633 ± 0.351
1.9HisHis: 1.9 ± 0.075
2.533HisIle: 2.533 ± 0.851
1.267HisLys: 1.267 ± 0.426
1.9HisLeu: 1.9 ± 1.202
0.0HisMet: 0.0 ± 0.0
1.267HisAsn: 1.267 ± 0.426
1.9HisPro: 1.9 ± 1.053
0.633HisGln: 0.633 ± 0.351
0.0HisArg: 0.0 ± 0.0
1.267HisSer: 1.267 ± 0.426
0.633HisThr: 0.633 ± 0.351
1.267HisVal: 1.267 ± 0.426
0.0HisTrp: 0.0 ± 0.0
0.633HisTyr: 0.633 ± 0.777
0.0HisXaa: 0.0 ± 0.0
Ile
3.167IleAla: 3.167 ± 0.627
3.167IleCys: 3.167 ± 1.628
2.533IleAsp: 2.533 ± 1.404
1.267IleGlu: 1.267 ± 1.553
1.267IlePhe: 1.267 ± 0.426
3.8IleGly: 3.8 ± 0.978
0.633IleHis: 0.633 ± 0.351
1.9IleIle: 1.9 ± 1.202
2.533IleLys: 2.533 ± 0.851
7.6IleLeu: 7.6 ± 0.299
0.633IleMet: 0.633 ± 0.777
1.9IleAsn: 1.9 ± 0.075
3.167IlePro: 3.167 ± 0.5
0.633IleGln: 0.633 ± 0.351
1.267IleArg: 1.267 ± 1.553
5.7IleSer: 5.7 ± 0.224
3.167IleThr: 3.167 ± 0.5
3.8IleVal: 3.8 ± 2.106
1.267IleTrp: 1.267 ± 0.702
0.633IleTyr: 0.633 ± 0.351
0.0IleXaa: 0.0 ± 0.0
Lys
3.8LysAla: 3.8 ± 0.978
0.0LysCys: 0.0 ± 0.0
2.533LysAsp: 2.533 ± 1.404
2.533LysGlu: 2.533 ± 0.276
1.267LysPhe: 1.267 ± 1.553
2.533LysGly: 2.533 ± 1.404
2.533LysHis: 2.533 ± 0.851
1.267LysIle: 1.267 ± 1.553
1.267LysLys: 1.267 ± 0.702
4.433LysLeu: 4.433 ± 1.33
2.533LysMet: 2.533 ± 0.851
1.9LysAsn: 1.9 ± 1.053
1.9LysPro: 1.9 ± 1.202
1.9LysGln: 1.9 ± 0.075
3.167LysArg: 3.167 ± 1.755
3.8LysSer: 3.8 ± 2.106
2.533LysThr: 2.533 ± 0.276
3.8LysVal: 3.8 ± 1.277
1.267LysTrp: 1.267 ± 0.426
2.533LysTyr: 2.533 ± 1.979
0.0LysXaa: 0.0 ± 0.0
Leu
5.066LeuAla: 5.066 ± 1.703
3.8LeuCys: 3.8 ± 0.978
3.8LeuAsp: 3.8 ± 0.978
6.333LeuGlu: 6.333 ± 2.383
4.433LeuPhe: 4.433 ± 0.926
3.8LeuGly: 3.8 ± 0.149
4.433LeuHis: 4.433 ± 0.202
3.8LeuIle: 3.8 ± 0.149
5.066LeuLys: 5.066 ± 0.575
10.133LeuLeu: 10.133 ± 0.022
4.433LeuMet: 4.433 ± 0.202
4.433LeuAsn: 4.433 ± 1.33
3.167LeuPro: 3.167 ± 0.627
2.533LeuGln: 2.533 ± 0.851
6.966LeuArg: 6.966 ± 0.478
10.766LeuSer: 10.766 ± 1.927
8.866LeuThr: 8.866 ± 0.404
5.066LeuVal: 5.066 ± 1.681
1.267LeuTrp: 1.267 ± 0.426
3.167LeuTyr: 3.167 ± 2.756
0.0LeuXaa: 0.0 ± 0.0
Met
3.167MetAla: 3.167 ± 0.627
1.267MetCys: 1.267 ± 0.702
0.0MetAsp: 0.0 ± 0.0
2.533MetGlu: 2.533 ± 0.276
1.9MetPhe: 1.9 ± 0.075
2.533MetGly: 2.533 ± 0.851
0.633MetHis: 0.633 ± 0.777
2.533MetIle: 2.533 ± 0.276
0.0MetLys: 0.0 ± 0.0
3.167MetLeu: 3.167 ± 1.628
2.533MetMet: 2.533 ± 0.851
1.267MetAsn: 1.267 ± 0.702
1.9MetPro: 1.9 ± 0.075
0.633MetGln: 0.633 ± 0.777
3.167MetArg: 3.167 ± 0.627
1.267MetSer: 1.267 ± 0.426
0.633MetThr: 0.633 ± 0.777
1.9MetVal: 1.9 ± 2.33
0.633MetTrp: 0.633 ± 0.351
0.633MetTyr: 0.633 ± 0.351
0.0MetXaa: 0.0 ± 0.0
Asn
3.8AsnAla: 3.8 ± 2.106
0.0AsnCys: 0.0 ± 0.0
2.533AsnAsp: 2.533 ± 0.276
1.267AsnGlu: 1.267 ± 0.702
0.0AsnPhe: 0.0 ± 0.0
3.167AsnGly: 3.167 ± 0.5
2.533AsnHis: 2.533 ± 0.276
0.633AsnIle: 0.633 ± 0.351
3.167AsnLys: 3.167 ± 0.627
2.533AsnLeu: 2.533 ± 1.404
3.8AsnMet: 3.8 ± 0.381
1.9AsnAsn: 1.9 ± 0.075
0.633AsnPro: 0.633 ± 0.777
1.9AsnGln: 1.9 ± 1.053
1.267AsnArg: 1.267 ± 0.426
1.9AsnSer: 1.9 ± 0.075
2.533AsnThr: 2.533 ± 0.276
3.167AsnVal: 3.167 ± 2.756
0.0AsnTrp: 0.0 ± 0.0
1.267AsnTyr: 1.267 ± 0.702
0.0AsnXaa: 0.0 ± 0.0
Pro
1.267ProAla: 1.267 ± 0.426
0.633ProCys: 0.633 ± 0.777
3.167ProAsp: 3.167 ± 0.5
4.433ProGlu: 4.433 ± 0.202
1.9ProPhe: 1.9 ± 1.053
3.167ProGly: 3.167 ± 0.627
1.267ProHis: 1.267 ± 0.426
3.167ProIle: 3.167 ± 0.5
1.9ProLys: 1.9 ± 1.053
5.066ProLeu: 5.066 ± 1.703
1.9ProMet: 1.9 ± 1.202
2.533ProAsn: 2.533 ± 0.276
5.7ProPro: 5.7 ± 1.352
1.267ProGln: 1.267 ± 0.702
3.167ProArg: 3.167 ± 1.755
3.167ProSer: 3.167 ± 0.627
4.433ProThr: 4.433 ± 1.33
5.066ProVal: 5.066 ± 1.703
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.9GlnAla: 1.9 ± 1.053
0.0GlnCys: 0.0 ± 0.0
0.633GlnAsp: 0.633 ± 0.777
0.633GlnGlu: 0.633 ± 0.351
2.533GlnPhe: 2.533 ± 0.276
0.633GlnGly: 0.633 ± 0.777
0.0GlnHis: 0.0 ± 0.0
5.066GlnIle: 5.066 ± 0.575
1.267GlnLys: 1.267 ± 0.702
4.433GlnLeu: 4.433 ± 0.202
0.633GlnMet: 0.633 ± 0.351
1.267GlnAsn: 1.267 ± 1.553
2.533GlnPro: 2.533 ± 1.404
0.0GlnGln: 0.0 ± 0.0
1.267GlnArg: 1.267 ± 1.553
1.9GlnSer: 1.9 ± 1.053
2.533GlnThr: 2.533 ± 0.276
3.167GlnVal: 3.167 ± 1.755
0.0GlnTrp: 0.0 ± 0.0
2.533GlnTyr: 2.533 ± 1.404
0.0GlnXaa: 0.0 ± 0.0
Arg
3.167ArgAla: 3.167 ± 0.627
0.633ArgCys: 0.633 ± 0.351
1.9ArgAsp: 1.9 ± 0.075
1.9ArgGlu: 1.9 ± 1.202
1.267ArgPhe: 1.267 ± 1.553
3.167ArgGly: 3.167 ± 1.755
0.633ArgHis: 0.633 ± 0.351
3.167ArgIle: 3.167 ± 0.627
2.533ArgLys: 2.533 ± 0.276
7.6ArgLeu: 7.6 ± 0.299
2.533ArgMet: 2.533 ± 0.851
1.267ArgAsn: 1.267 ± 0.702
3.167ArgPro: 3.167 ± 0.627
2.533ArgGln: 2.533 ± 0.851
3.167ArgArg: 3.167 ± 0.627
6.966ArgSer: 6.966 ± 0.65
6.333ArgThr: 6.333 ± 3.51
1.9ArgVal: 1.9 ± 1.053
0.633ArgTrp: 0.633 ± 0.777
3.8ArgTyr: 3.8 ± 0.978
0.0ArgXaa: 0.0 ± 0.0
Ser
1.267SerAla: 1.267 ± 0.702
1.267SerCys: 1.267 ± 0.702
8.233SerAsp: 8.233 ± 1.18
5.066SerGlu: 5.066 ± 0.575
4.433SerPhe: 4.433 ± 0.926
5.066SerGly: 5.066 ± 2.83
0.0SerHis: 0.0 ± 0.0
3.8SerIle: 3.8 ± 0.978
1.9SerLys: 1.9 ± 1.053
10.133SerLeu: 10.133 ± 1.106
0.633SerMet: 0.633 ± 0.777
2.533SerAsn: 2.533 ± 0.276
5.7SerPro: 5.7 ± 0.224
3.8SerGln: 3.8 ± 0.149
8.233SerArg: 8.233 ± 1.18
6.966SerSer: 6.966 ± 1.777
8.233SerThr: 8.233 ± 1.075
3.8SerVal: 3.8 ± 2.106
1.267SerTrp: 1.267 ± 0.426
3.8SerTyr: 3.8 ± 0.978
0.0SerXaa: 0.0 ± 0.0
Thr
5.066ThrAla: 5.066 ± 0.575
0.633ThrCys: 0.633 ± 0.351
1.267ThrAsp: 1.267 ± 0.426
2.533ThrGlu: 2.533 ± 1.404
3.167ThrPhe: 3.167 ± 0.5
3.8ThrGly: 3.8 ± 1.277
0.633ThrHis: 0.633 ± 0.351
2.533ThrIle: 2.533 ± 1.404
2.533ThrLys: 2.533 ± 0.276
6.333ThrLeu: 6.333 ± 0.127
0.633ThrMet: 0.633 ± 0.351
1.9ThrAsn: 1.9 ± 0.075
2.533ThrPro: 2.533 ± 0.276
0.633ThrGln: 0.633 ± 0.351
3.167ThrArg: 3.167 ± 0.5
5.7ThrSer: 5.7 ± 0.224
3.167ThrThr: 3.167 ± 1.755
7.6ThrVal: 7.6 ± 1.957
1.9ThrTrp: 1.9 ± 0.075
3.8ThrTyr: 3.8 ± 0.978
0.0ThrXaa: 0.0 ± 0.0
Val
5.066ValAla: 5.066 ± 1.703
3.8ValCys: 3.8 ± 0.149
5.066ValAsp: 5.066 ± 1.703
3.8ValGlu: 3.8 ± 0.978
2.533ValPhe: 2.533 ± 1.979
5.066ValGly: 5.066 ± 0.575
0.0ValHis: 0.0 ± 0.0
1.267ValIle: 1.267 ± 0.426
4.433ValLys: 4.433 ± 0.202
8.233ValLeu: 8.233 ± 0.052
1.9ValMet: 1.9 ± 0.075
2.533ValAsn: 2.533 ± 1.404
5.066ValPro: 5.066 ± 0.575
1.9ValGln: 1.9 ± 0.075
3.8ValArg: 3.8 ± 2.106
8.233ValSer: 8.233 ± 1.18
3.8ValThr: 3.8 ± 0.978
3.8ValVal: 3.8 ± 1.277
0.0ValTrp: 0.0 ± 0.0
0.633ValTyr: 0.633 ± 0.777
0.0ValXaa: 0.0 ± 0.0
Trp
1.267TrpAla: 1.267 ± 1.553
0.0TrpCys: 0.0 ± 0.0
1.267TrpAsp: 1.267 ± 0.426
0.633TrpGlu: 0.633 ± 0.351
2.533TrpPhe: 2.533 ± 1.404
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.633TrpIle: 0.633 ± 0.351
1.267TrpLys: 1.267 ± 1.553
2.533TrpLeu: 2.533 ± 1.979
0.0TrpMet: 0.0 ± 0.0
0.633TrpAsn: 0.633 ± 0.351
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.633TrpArg: 0.633 ± 0.777
1.9TrpSer: 1.9 ± 1.202
1.267TrpThr: 1.267 ± 0.426
0.633TrpVal: 0.633 ± 0.351
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.8TyrAla: 3.8 ± 2.106
0.633TyrCys: 0.633 ± 0.777
3.8TyrAsp: 3.8 ± 0.149
0.633TyrGlu: 0.633 ± 0.777
0.633TyrPhe: 0.633 ± 0.777
3.8TyrGly: 3.8 ± 0.978
0.0TyrHis: 0.0 ± 0.0
0.633TyrIle: 0.633 ± 0.351
0.633TyrLys: 0.633 ± 0.777
5.066TyrLeu: 5.066 ± 0.575
1.267TyrMet: 1.267 ± 1.553
1.267TyrAsn: 1.267 ± 0.426
1.9TyrPro: 1.9 ± 0.075
0.0TyrGln: 0.0 ± 0.0
2.533TyrArg: 2.533 ± 0.276
1.267TyrSer: 1.267 ± 0.426
2.533TyrThr: 2.533 ± 0.276
3.8TyrVal: 3.8 ± 0.978
1.267TyrTrp: 1.267 ± 1.553
0.633TyrTyr: 0.633 ± 0.351
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1580 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski