Amino acid dipepetide frequency for Bacteroides finegoldii CL09T03C10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.374AlaAla: 5.374 ± 0.072	0.915AlaCys: 0.915 ± 0.028	4.123AlaAsp: 4.123 ± 0.051	4.705AlaGlu: 4.705 ± 0.07	3.022AlaPhe: 3.022 ± 0.041	4.832AlaGly: 4.832 ± 0.066	1.147AlaHis: 1.147 ± 0.027	4.743AlaIle: 4.743 ± 0.063	4.153AlaLys: 4.153 ± 0.06	6.34AlaLeu: 6.34 ± 0.074	1.945AlaMet: 1.945 ± 0.041	3.247AlaAsn: 3.247 ± 0.05	2.177AlaPro: 2.177 ± 0.042	2.621AlaGln: 2.621 ± 0.051	2.911AlaArg: 2.911 ± 0.046	4.164AlaSer: 4.164 ± 0.057	3.887AlaThr: 3.887 ± 0.056	4.605AlaVal: 4.605 ± 0.071	0.8AlaTrp: 0.8 ± 0.024	2.931AlaTyr: 2.931 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.73CysAla: 0.73 ± 0.021	0.221CysCys: 0.221 ± 0.013	0.642CysAsp: 0.642 ± 0.02	0.705CysGlu: 0.705 ± 0.024	0.638CysPhe: 0.638 ± 0.021	0.992CysGly: 0.992 ± 0.026	0.276CysHis: 0.276 ± 0.015	0.92CysIle: 0.92 ± 0.026	0.731CysLys: 0.731 ± 0.024	1.118CysLeu: 1.118 ± 0.026	0.336CysMet: 0.336 ± 0.014	0.565CysAsn: 0.565 ± 0.019	0.511CysPro: 0.511 ± 0.021	0.345CysGln: 0.345 ± 0.013	0.625CysArg: 0.625 ± 0.022	0.797CysSer: 0.797 ± 0.023	0.676CysThr: 0.676 ± 0.02	0.723CysVal: 0.723 ± 0.023	0.162CysTrp: 0.162 ± 0.011	0.582CysTyr: 0.582 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.781AspAla: 3.781 ± 0.057	0.632AspCys: 0.632 ± 0.021	2.729AspAsp: 2.729 ± 0.041	3.993AspGlu: 3.993 ± 0.058	2.988AspPhe: 2.988 ± 0.047	4.234AspGly: 4.234 ± 0.065	0.774AspHis: 0.774 ± 0.025	4.154AspIle: 4.154 ± 0.054	4.232AspLys: 4.232 ± 0.056	4.613AspLeu: 4.613 ± 0.061	1.621AspMet: 1.621 ± 0.032	2.879AspAsn: 2.879 ± 0.047	1.913AspPro: 1.913 ± 0.039	1.198AspGln: 1.198 ± 0.033	2.388AspArg: 2.388 ± 0.041	3.087AspSer: 3.087 ± 0.051	2.789AspThr: 2.789 ± 0.047	3.471AspVal: 3.471 ± 0.051	0.93AspTrp: 0.93 ± 0.028	3.05AspTyr: 3.05 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.848GluAla: 4.848 ± 0.071	0.668GluCys: 0.668 ± 0.019	3.333GluAsp: 3.333 ± 0.048	5.451GluGlu: 5.451 ± 0.09	2.582GluPhe: 2.582 ± 0.049	4.186GluGly: 4.186 ± 0.053	1.228GluHis: 1.228 ± 0.026	4.715GluIle: 4.715 ± 0.059	5.539GluLys: 5.539 ± 0.075	6.4GluLeu: 6.4 ± 0.068	2.038GluMet: 2.038 ± 0.035	3.628GluAsn: 3.628 ± 0.049	1.835GluPro: 1.835 ± 0.032	2.821GluGln: 2.821 ± 0.05	3.402GluArg: 3.402 ± 0.061	3.304GluSer: 3.304 ± 0.048	3.358GluThr: 3.358 ± 0.047	4.335GluVal: 4.335 ± 0.05	0.892GluTrp: 0.892 ± 0.025	2.952GluTyr: 2.952 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.006PheAla: 3.006 ± 0.051	0.684PheCys: 0.684 ± 0.02	2.723PheAsp: 2.723 ± 0.037	2.51PheGlu: 2.51 ± 0.043	2.199PhePhe: 2.199 ± 0.04	3.18PheGly: 3.18 ± 0.051	0.84PheHis: 0.84 ± 0.026	3.205PheIle: 3.205 ± 0.051	2.469PheLys: 2.469 ± 0.04	4.065PheLeu: 4.065 ± 0.062	1.255PheMet: 1.255 ± 0.034	2.476PheAsn: 2.476 ± 0.044	1.752PhePro: 1.752 ± 0.037	1.337PheGln: 1.337 ± 0.028	2.151PheArg: 2.151 ± 0.037	3.374PheSer: 3.374 ± 0.051	2.795PheThr: 2.795 ± 0.048	2.803PheVal: 2.803 ± 0.043	0.564PheTrp: 0.564 ± 0.02	2.086PheTyr: 2.086 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.228GlyAla: 4.228 ± 0.068	0.886GlyCys: 0.886 ± 0.024	3.532GlyAsp: 3.532 ± 0.047	4.374GlyGlu: 4.374 ± 0.064	3.141GlyPhe: 3.141 ± 0.053	4.572GlyGly: 4.572 ± 0.082	1.192GlyHis: 1.192 ± 0.027	5.344GlyIle: 5.344 ± 0.068	5.454GlyLys: 5.454 ± 0.059	5.762GlyLeu: 5.762 ± 0.069	2.122GlyMet: 2.122 ± 0.039	3.597GlyAsn: 3.597 ± 0.058	1.238GlyPro: 1.238 ± 0.033	2.017GlyGln: 2.017 ± 0.041	2.908GlyArg: 2.908 ± 0.049	3.905GlySer: 3.905 ± 0.06	4.243GlyThr: 4.243 ± 0.058	4.687GlyVal: 4.687 ± 0.07	1.051GlyTrp: 1.051 ± 0.028	3.463GlyTyr: 3.463 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.027HisAla: 1.027 ± 0.026	0.307HisCys: 0.307 ± 0.014	0.881HisAsp: 0.881 ± 0.023	0.995HisGlu: 0.995 ± 0.026	1.028HisPhe: 1.028 ± 0.028	1.17HisGly: 1.17 ± 0.033	0.456HisHis: 0.456 ± 0.02	1.436HisIle: 1.436 ± 0.031	1.041HisLys: 1.041 ± 0.024	1.669HisLeu: 1.669 ± 0.035	0.328HisMet: 0.328 ± 0.015	0.881HisAsn: 0.881 ± 0.022	1.043HisPro: 1.043 ± 0.026	0.601HisGln: 0.601 ± 0.019	0.871HisArg: 0.871 ± 0.022	1.118HisSer: 1.118 ± 0.029	1.049HisThr: 1.049 ± 0.027	0.913HisVal: 0.913 ± 0.024	0.275HisTrp: 0.275 ± 0.012	0.9HisTyr: 0.9 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.107IleAla: 5.107 ± 0.066	0.975IleCys: 0.975 ± 0.025	4.238IleAsp: 4.238 ± 0.052	4.664IleGlu: 4.664 ± 0.06	2.717IlePhe: 2.717 ± 0.047	4.749IleGly: 4.749 ± 0.056	1.352IleHis: 1.352 ± 0.028	4.63IleIle: 4.63 ± 0.065	4.211IleLys: 4.211 ± 0.05	6.005IleLeu: 6.005 ± 0.073	1.459IleMet: 1.459 ± 0.027	3.534IleAsn: 3.534 ± 0.054	3.162IlePro: 3.162 ± 0.047	2.264IleGln: 2.264 ± 0.038	3.578IleArg: 3.578 ± 0.043	4.678IleSer: 4.678 ± 0.061	4.098IleThr: 4.098 ± 0.053	4.257IleVal: 4.257 ± 0.057	0.726IleTrp: 0.726 ± 0.022	2.923IleTyr: 2.923 ± 0.053	0.0IleXaa: 0.0 ± 0.0
Lys	4.968LysAla: 4.968 ± 0.062	0.571LysCys: 0.571 ± 0.021	4.216LysAsp: 4.216 ± 0.062	6.183LysGlu: 6.183 ± 0.084	2.28LysPhe: 2.28 ± 0.041	4.733LysGly: 4.733 ± 0.053	1.224LysHis: 1.224 ± 0.03	4.268LysIle: 4.268 ± 0.055	5.464LysLys: 5.464 ± 0.065	5.5LysLeu: 5.5 ± 0.06	2.179LysMet: 2.179 ± 0.04	3.706LysAsn: 3.706 ± 0.051	2.133LysPro: 2.133 ± 0.04	2.661LysGln: 2.661 ± 0.049	3.229LysArg: 3.229 ± 0.044	3.483LysSer: 3.483 ± 0.051	3.598LysThr: 3.598 ± 0.056	4.505LysVal: 4.505 ± 0.057	0.834LysTrp: 0.834 ± 0.025	3.107LysTyr: 3.107 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	6.061LeuAla: 6.061 ± 0.069	1.289LeuCys: 1.289 ± 0.028	4.597LeuAsp: 4.597 ± 0.059	5.167LeuGlu: 5.167 ± 0.071	4.484LeuPhe: 4.484 ± 0.059	5.401LeuGly: 5.401 ± 0.072	1.671LeuHis: 1.671 ± 0.035	5.546LeuIle: 5.546 ± 0.076	6.52LeuLys: 6.52 ± 0.064	8.782LeuLeu: 8.782 ± 0.101	2.373LeuMet: 2.373 ± 0.045	4.742LeuAsn: 4.742 ± 0.058	4.033LeuPro: 4.033 ± 0.056	3.375LeuGln: 3.375 ± 0.047	4.204LeuArg: 4.204 ± 0.049	6.637LeuSer: 6.637 ± 0.086	5.259LeuThr: 5.259 ± 0.062	5.058LeuVal: 5.058 ± 0.061	1.053LeuTrp: 1.053 ± 0.027	3.75LeuTyr: 3.75 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	1.992MetAla: 1.992 ± 0.037	0.257MetCys: 0.257 ± 0.014	1.537MetAsp: 1.537 ± 0.034	1.938MetGlu: 1.938 ± 0.039	0.997MetPhe: 0.997 ± 0.026	1.81MetGly: 1.81 ± 0.037	0.438MetHis: 0.438 ± 0.019	1.673MetIle: 1.673 ± 0.035	2.696MetLys: 2.696 ± 0.037	2.381MetLeu: 2.381 ± 0.041	0.8MetMet: 0.8 ± 0.027	1.649MetAsn: 1.649 ± 0.031	1.057MetPro: 1.057 ± 0.025	1.045MetGln: 1.045 ± 0.026	1.309MetArg: 1.309 ± 0.034	1.545MetSer: 1.545 ± 0.028	1.514MetThr: 1.514 ± 0.031	1.596MetVal: 1.596 ± 0.035	0.276MetTrp: 0.276 ± 0.014	0.94MetTyr: 0.94 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.408AsnAla: 3.408 ± 0.047	0.544AsnCys: 0.544 ± 0.018	2.722AsnAsp: 2.722 ± 0.047	3.27AsnGlu: 3.27 ± 0.053	2.325AsnPhe: 2.325 ± 0.044	4.061AsnGly: 4.061 ± 0.054	0.927AsnHis: 0.927 ± 0.026	3.872AsnIle: 3.872 ± 0.058	3.44AsnLys: 3.44 ± 0.054	4.387AsnLeu: 4.387 ± 0.062	1.349AsnMet: 1.349 ± 0.029	2.797AsnAsn: 2.797 ± 0.058	2.514AsnPro: 2.514 ± 0.045	1.713AsnGln: 1.713 ± 0.038	2.55AsnArg: 2.55 ± 0.043	2.91AsnSer: 2.91 ± 0.047	2.738AsnThr: 2.738 ± 0.044	3.263AsnVal: 3.263 ± 0.053	0.684AsnTrp: 0.684 ± 0.021	2.456AsnTyr: 2.456 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	2.621ProAla: 2.621 ± 0.042	0.372ProCys: 0.372 ± 0.016	2.49ProAsp: 2.49 ± 0.04	3.379ProGlu: 3.379 ± 0.046	1.812ProPhe: 1.812 ± 0.038	2.356ProGly: 2.356 ± 0.042	0.631ProHis: 0.631 ± 0.021	2.346ProIle: 2.346 ± 0.043	2.062ProLys: 2.062 ± 0.042	3.198ProLeu: 3.198 ± 0.049	0.96ProMet: 0.96 ± 0.028	1.753ProAsn: 1.753 ± 0.037	0.796ProPro: 0.796 ± 0.029	1.394ProGln: 1.394 ± 0.031	1.32ProArg: 1.32 ± 0.028	2.228ProSer: 2.228 ± 0.033	1.975ProThr: 1.975 ± 0.034	2.945ProVal: 2.945 ± 0.05	0.427ProTrp: 0.427 ± 0.018	1.786ProTyr: 1.786 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.447GlnAla: 2.447 ± 0.046	0.317GlnCys: 0.317 ± 0.015	1.613GlnAsp: 1.613 ± 0.031	2.382GlnGlu: 2.382 ± 0.041	1.359GlnPhe: 1.359 ± 0.029	2.067GlnGly: 2.067 ± 0.039	0.615GlnHis: 0.615 ± 0.022	2.365GlnIle: 2.365 ± 0.042	2.576GlnLys: 2.576 ± 0.049	3.344GlnLeu: 3.344 ± 0.054	1.059GlnMet: 1.059 ± 0.024	1.719GlnAsn: 1.719 ± 0.038	1.294GlnPro: 1.294 ± 0.035	1.613GlnGln: 1.613 ± 0.04	1.696GlnArg: 1.696 ± 0.037	1.988GlnSer: 1.988 ± 0.042	2.042GlnThr: 2.042 ± 0.039	2.123GlnVal: 2.123 ± 0.039	0.485GlnTrp: 0.485 ± 0.022	1.524GlnTyr: 1.524 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.667ArgAla: 2.667 ± 0.042	0.498ArgCys: 0.498 ± 0.019	2.185ArgAsp: 2.185 ± 0.042	3.06ArgGlu: 3.06 ± 0.055	2.326ArgPhe: 2.326 ± 0.045	2.403ArgGly: 2.403 ± 0.04	0.864ArgHis: 0.864 ± 0.025	3.731ArgIle: 3.731 ± 0.053	3.562ArgLys: 3.562 ± 0.057	4.37ArgLeu: 4.37 ± 0.054	1.556ArgMet: 1.556 ± 0.04	2.579ArgAsn: 2.579 ± 0.045	1.621ArgPro: 1.621 ± 0.038	1.801ArgGln: 1.801 ± 0.041	2.222ArgArg: 2.222 ± 0.049	2.458ArgSer: 2.458 ± 0.039	2.535ArgThr: 2.535 ± 0.038	2.688ArgVal: 2.688 ± 0.041	0.678ArgTrp: 0.678 ± 0.022	2.234ArgTyr: 2.234 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.1SerAla: 4.1 ± 0.065	0.837SerCys: 0.837 ± 0.025	3.43SerAsp: 3.43 ± 0.056	3.677SerGlu: 3.677 ± 0.052	3.266SerPhe: 3.266 ± 0.052	4.435SerGly: 4.435 ± 0.066	1.105SerHis: 1.105 ± 0.028	4.452SerIle: 4.452 ± 0.062	3.549SerLys: 3.549 ± 0.039	5.975SerLeu: 5.975 ± 0.067	1.567SerMet: 1.567 ± 0.029	2.799SerAsn: 2.799 ± 0.05	2.29SerPro: 2.29 ± 0.043	1.922SerGln: 1.922 ± 0.035	2.558SerArg: 2.558 ± 0.049	4.033SerSer: 4.033 ± 0.075	3.29SerThr: 3.29 ± 0.05	4.176SerVal: 4.176 ± 0.065	0.856SerTrp: 0.856 ± 0.027	2.86SerTyr: 2.86 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	3.96ThrAla: 3.96 ± 0.056	0.592ThrCys: 0.592 ± 0.019	3.505ThrAsp: 3.505 ± 0.048	3.499ThrGlu: 3.499 ± 0.051	2.815ThrPhe: 2.815 ± 0.038	4.477ThrGly: 4.477 ± 0.057	1.0ThrHis: 1.0 ± 0.03	3.82ThrIle: 3.82 ± 0.049	2.961ThrLys: 2.961 ± 0.046	5.366ThrLeu: 5.366 ± 0.066	1.258ThrMet: 1.258 ± 0.025	2.552ThrAsn: 2.552 ± 0.047	2.732ThrPro: 2.732 ± 0.04	1.776ThrGln: 1.776 ± 0.032	2.169ThrArg: 2.169 ± 0.041	3.423ThrSer: 3.423 ± 0.052	3.135ThrThr: 3.135 ± 0.06	3.999ThrVal: 3.999 ± 0.048	0.709ThrTrp: 0.709 ± 0.025	2.539ThrTyr: 2.539 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	4.443ValAla: 4.443 ± 0.062	0.963ValCys: 0.963 ± 0.024	3.631ValAsp: 3.631 ± 0.05	4.103ValGlu: 4.103 ± 0.055	2.742ValPhe: 2.742 ± 0.043	4.06ValGly: 4.06 ± 0.062	1.089ValHis: 1.089 ± 0.028	4.304ValIle: 4.304 ± 0.054	4.33ValLys: 4.33 ± 0.062	5.532ValLeu: 5.532 ± 0.063	1.691ValMet: 1.691 ± 0.035	3.339ValAsn: 3.339 ± 0.05	2.531ValPro: 2.531 ± 0.045	1.936ValGln: 1.936 ± 0.038	2.992ValArg: 2.992 ± 0.048	4.49ValSer: 4.49 ± 0.059	3.815ValThr: 3.815 ± 0.058	4.298ValVal: 4.298 ± 0.06	0.765ValTrp: 0.765 ± 0.022	2.688ValTyr: 2.688 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.794TrpAla: 0.794 ± 0.027	0.181TrpCys: 0.181 ± 0.01	0.745TrpAsp: 0.745 ± 0.026	0.873TrpGlu: 0.873 ± 0.026	0.588TrpPhe: 0.588 ± 0.018	0.976TrpGly: 0.976 ± 0.025	0.252TrpHis: 0.252 ± 0.011	0.864TrpIle: 0.864 ± 0.029	0.988TrpLys: 0.988 ± 0.024	1.135TrpLeu: 1.135 ± 0.027	0.45TrpMet: 0.45 ± 0.016	0.887TrpAsn: 0.887 ± 0.025	0.268TrpPro: 0.268 ± 0.014	0.534TrpGln: 0.534 ± 0.019	0.592TrpArg: 0.592 ± 0.021	0.707TrpSer: 0.707 ± 0.026	0.688TrpThr: 0.688 ± 0.02	0.721TrpVal: 0.721 ± 0.024	0.211TrpTrp: 0.211 ± 0.014	0.567TrpTyr: 0.567 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.078TyrAla: 3.078 ± 0.052	0.583TyrCys: 0.583 ± 0.018	2.579TyrAsp: 2.579 ± 0.04	2.589TyrGlu: 2.589 ± 0.047	2.164TyrPhe: 2.164 ± 0.042	3.025TyrGly: 3.025 ± 0.045	0.912TyrHis: 0.912 ± 0.025	2.939TyrIle: 2.939 ± 0.049	2.863TyrLys: 2.863 ± 0.049	4.062TyrLeu: 4.062 ± 0.061	1.106TyrMet: 1.106 ± 0.026	2.601TyrAsn: 2.601 ± 0.05	1.95TyrPro: 1.95 ± 0.038	1.654TyrGln: 1.654 ± 0.034	2.367TyrArg: 2.367 ± 0.042	2.848TyrSer: 2.848 ± 0.043	2.801TyrThr: 2.801 ± 0.044	2.574TyrVal: 2.574 ± 0.044	0.643TyrTrp: 0.643 ± 0.021	2.283TyrTyr: 2.283 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4159 proteins (1522812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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