Amino acid dipepetide frequency for Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.757AlaAla: 4.757 ± 0.07
0.613AlaCys: 0.613 ± 0.014
2.836AlaAsp: 2.836 ± 0.031
3.469AlaGlu: 3.469 ± 0.042
2.257AlaPhe: 2.257 ± 0.029
3.339AlaGly: 3.339 ± 0.044
1.161AlaHis: 1.161 ± 0.02
3.723AlaIle: 3.723 ± 0.039
4.356AlaLys: 4.356 ± 0.05
5.339AlaLeu: 5.339 ± 0.054
1.198AlaMet: 1.198 ± 0.022
3.567AlaAsn: 3.567 ± 0.04
2.538AlaPro: 2.538 ± 0.044
2.485AlaGln: 2.485 ± 0.038
2.459AlaArg: 2.459 ± 0.034
5.419AlaSer: 5.419 ± 0.053
4.032AlaThr: 4.032 ± 0.052
3.235AlaVal: 3.235 ± 0.04
0.452AlaTrp: 0.452 ± 0.013
1.713AlaTyr: 1.713 ± 0.026
0.0AlaXaa: 0.0 ± 0.0
Cys
0.557CysAla: 0.557 ± 0.015
0.24CysCys: 0.24 ± 0.011
0.564CysAsp: 0.564 ± 0.015
0.552CysGlu: 0.552 ± 0.014
0.614CysPhe: 0.614 ± 0.016
0.718CysGly: 0.718 ± 0.02
0.27CysHis: 0.27 ± 0.01
0.756CysIle: 0.756 ± 0.019
0.655CysLys: 0.655 ± 0.018
1.118CysLeu: 1.118 ± 0.021
0.21CysMet: 0.21 ± 0.009
0.535CysAsn: 0.535 ± 0.014
0.426CysPro: 0.426 ± 0.014
0.4CysGln: 0.4 ± 0.011
0.43CysArg: 0.43 ± 0.012
0.798CysSer: 0.798 ± 0.018
0.542CysThr: 0.542 ± 0.016
0.662CysVal: 0.662 ± 0.017
0.147CysTrp: 0.147 ± 0.006
0.403CysTyr: 0.403 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
3.442AspAla: 3.442 ± 0.04
0.553AspCys: 0.553 ± 0.017
5.411AspAsp: 5.411 ± 0.089
5.316AspGlu: 5.316 ± 0.071
2.527AspPhe: 2.527 ± 0.029
3.15AspGly: 3.15 ± 0.035
1.143AspHis: 1.143 ± 0.021
3.609AspIle: 3.609 ± 0.037
3.612AspLys: 3.612 ± 0.049
5.657AspLeu: 5.657 ± 0.051
0.997AspMet: 0.997 ± 0.016
3.119AspAsn: 3.119 ± 0.041
2.335AspPro: 2.335 ± 0.035
2.056AspGln: 2.056 ± 0.03
1.9AspArg: 1.9 ± 0.025
4.324AspSer: 4.324 ± 0.046
2.763AspThr: 2.763 ± 0.033
3.521AspVal: 3.521 ± 0.041
0.585AspTrp: 0.585 ± 0.017
2.133AspTyr: 2.133 ± 0.034
0.0AspXaa: 0.0 ± 0.0
Glu
3.621GluAla: 3.621 ± 0.044
0.551GluCys: 0.551 ± 0.016
4.376GluAsp: 4.376 ± 0.061
7.153GluGlu: 7.153 ± 0.133
2.668GluPhe: 2.668 ± 0.033
2.923GluGly: 2.923 ± 0.036
1.331GluHis: 1.331 ± 0.028
4.159GluIle: 4.159 ± 0.048
5.39GluLys: 5.39 ± 0.072
6.381GluLeu: 6.381 ± 0.057
1.369GluMet: 1.369 ± 0.025
4.109GluAsn: 4.109 ± 0.045
2.017GluPro: 2.017 ± 0.045
3.11GluGln: 3.11 ± 0.045
2.777GluArg: 2.777 ± 0.037
4.774GluSer: 4.774 ± 0.061
3.58GluThr: 3.58 ± 0.043
3.672GluVal: 3.672 ± 0.051
0.574GluTrp: 0.574 ± 0.014
2.25GluTyr: 2.25 ± 0.03
0.0GluXaa: 0.0 ± 0.0
Phe
2.645PheAla: 2.645 ± 0.032
0.504PheCys: 0.504 ± 0.014
2.753PheAsp: 2.753 ± 0.029
2.666PheGlu: 2.666 ± 0.034
2.011PhePhe: 2.011 ± 0.038
2.648PheGly: 2.648 ± 0.045
0.99PheHis: 0.99 ± 0.021
2.737PheIle: 2.737 ± 0.034
2.907PheLys: 2.907 ± 0.031
3.829PheLeu: 3.829 ± 0.044
0.818PheMet: 0.818 ± 0.017
2.571PheAsn: 2.571 ± 0.03
1.683PhePro: 1.683 ± 0.031
1.794PheGln: 1.794 ± 0.024
1.549PheArg: 1.549 ± 0.025
3.146PheSer: 3.146 ± 0.04
2.412PheThr: 2.412 ± 0.032
2.566PheVal: 2.566 ± 0.037
0.482PheTrp: 0.482 ± 0.015
1.44PheTyr: 1.44 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
3.482GlyAla: 3.482 ± 0.051
0.617GlyCys: 0.617 ± 0.015
3.155GlyAsp: 3.155 ± 0.041
3.321GlyGlu: 3.321 ± 0.042
2.402GlyPhe: 2.402 ± 0.031
4.317GlyGly: 4.317 ± 0.074
1.177GlyHis: 1.177 ± 0.023
3.288GlyIle: 3.288 ± 0.042
3.804GlyLys: 3.804 ± 0.043
4.703GlyLeu: 4.703 ± 0.045
0.97GlyMet: 0.97 ± 0.02
3.246GlyAsn: 3.246 ± 0.043
1.571GlyPro: 1.571 ± 0.028
1.912GlyGln: 1.912 ± 0.029
2.118GlyArg: 2.118 ± 0.035
4.773GlySer: 4.773 ± 0.06
3.064GlyThr: 3.064 ± 0.052
3.508GlyVal: 3.508 ± 0.05
0.568GlyTrp: 0.568 ± 0.016
1.903GlyTyr: 1.903 ± 0.035
0.0GlyXaa: 0.0 ± 0.0
His
1.096HisAla: 1.096 ± 0.02
0.268HisCys: 0.268 ± 0.009
1.217HisAsp: 1.217 ± 0.024
1.365HisGlu: 1.365 ± 0.025
0.96HisPhe: 0.96 ± 0.019
1.244HisGly: 1.244 ± 0.024
1.114HisHis: 1.114 ± 0.03
1.374HisIle: 1.374 ± 0.021
1.369HisLys: 1.369 ± 0.02
2.319HisLeu: 2.319 ± 0.028
0.377HisMet: 0.377 ± 0.011
1.389HisAsn: 1.389 ± 0.023
1.217HisPro: 1.217 ± 0.025
1.449HisGln: 1.449 ± 0.033
1.002HisArg: 1.002 ± 0.018
1.86HisSer: 1.86 ± 0.031
1.219HisThr: 1.219 ± 0.025
1.125HisVal: 1.125 ± 0.021
0.219HisTrp: 0.219 ± 0.01
0.858HisTyr: 0.858 ± 0.016
0.0HisXaa: 0.0 ± 0.0
Ile
3.831IleAla: 3.831 ± 0.041
0.757IleCys: 0.757 ± 0.017
4.05IleAsp: 4.05 ± 0.034
4.069IleGlu: 4.069 ± 0.055
2.553IlePhe: 2.553 ± 0.037
3.208IleGly: 3.208 ± 0.039
1.357IleHis: 1.357 ± 0.021
3.92IleIle: 3.92 ± 0.053
4.199IleLys: 4.199 ± 0.044
5.89IleLeu: 5.89 ± 0.065
1.202IleMet: 1.202 ± 0.022
3.791IleAsn: 3.791 ± 0.041
3.042IlePro: 3.042 ± 0.038
2.28IleGln: 2.28 ± 0.032
2.44IleArg: 2.44 ± 0.032
5.056IleSer: 5.056 ± 0.057
3.589IleThr: 3.589 ± 0.04
3.711IleVal: 3.711 ± 0.043
0.652IleTrp: 0.652 ± 0.016
2.096IleTyr: 2.096 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
3.629LysAla: 3.629 ± 0.045
0.667LysCys: 0.667 ± 0.017
4.017LysAsp: 4.017 ± 0.048
5.313LysGlu: 5.313 ± 0.067
2.943LysPhe: 2.943 ± 0.032
2.891LysGly: 2.891 ± 0.035
1.597LysHis: 1.597 ± 0.024
4.278LysIle: 4.278 ± 0.046
5.843LysLys: 5.843 ± 0.072
7.476LysLeu: 7.476 ± 0.067
1.346LysMet: 1.346 ± 0.024
4.01LysAsn: 4.01 ± 0.047
2.864LysPro: 2.864 ± 0.035
3.34LysGln: 3.34 ± 0.043
3.627LysArg: 3.627 ± 0.041
5.417LysSer: 5.417 ± 0.057
3.741LysThr: 3.741 ± 0.04
3.957LysVal: 3.957 ± 0.037
0.673LysTrp: 0.673 ± 0.015
2.566LysTyr: 2.566 ± 0.032
0.0LysXaa: 0.0 ± 0.0
Leu
5.782LeuAla: 5.782 ± 0.056
1.107LeuCys: 1.107 ± 0.025
5.279LeuAsp: 5.279 ± 0.045
5.903LeuGlu: 5.903 ± 0.055
3.931LeuPhe: 3.931 ± 0.042
4.832LeuGly: 4.832 ± 0.04
2.262LeuHis: 2.262 ± 0.03
5.818LeuIle: 5.818 ± 0.053
7.003LeuLys: 7.003 ± 0.067
9.507LeuLeu: 9.507 ± 0.09
1.849LeuMet: 1.849 ± 0.029
5.691LeuAsn: 5.691 ± 0.056
4.568LeuPro: 4.568 ± 0.046
4.908LeuGln: 4.908 ± 0.059
4.319LeuArg: 4.319 ± 0.044
8.005LeuSer: 8.005 ± 0.055
5.14LeuThr: 5.14 ± 0.044
5.666LeuVal: 5.666 ± 0.056
0.764LeuTrp: 0.764 ± 0.019
3.042LeuTyr: 3.042 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
1.211MetAla: 1.211 ± 0.021
0.228MetCys: 0.228 ± 0.008
1.085MetAsp: 1.085 ± 0.018
1.206MetGlu: 1.206 ± 0.024
0.772MetPhe: 0.772 ± 0.019
1.08MetGly: 1.08 ± 0.021
0.361MetHis: 0.361 ± 0.012
1.217MetIle: 1.217 ± 0.032
1.37MetLys: 1.37 ± 0.021
1.692MetLeu: 1.692 ± 0.028
0.519MetMet: 0.519 ± 0.017
1.121MetAsn: 1.121 ± 0.019
0.752MetPro: 0.752 ± 0.019
0.827MetGln: 0.827 ± 0.022
0.777MetArg: 0.777 ± 0.019
1.863MetSer: 1.863 ± 0.025
1.116MetThr: 1.116 ± 0.022
1.06MetVal: 1.06 ± 0.021
0.164MetTrp: 0.164 ± 0.009
0.577MetTyr: 0.577 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.403AsnAla: 3.403 ± 0.038
0.599AsnCys: 0.599 ± 0.016
3.866AsnAsp: 3.866 ± 0.042
4.08AsnGlu: 4.08 ± 0.044
2.449AsnPhe: 2.449 ± 0.031
3.794AsnGly: 3.794 ± 0.052
1.406AsnHis: 1.406 ± 0.026
3.477AsnIle: 3.477 ± 0.037
3.967AsnLys: 3.967 ± 0.048
5.466AsnLeu: 5.466 ± 0.049
1.025AsnMet: 1.025 ± 0.016
5.844AsnAsn: 5.844 ± 0.117
2.406AsnPro: 2.406 ± 0.028
2.527AsnGln: 2.527 ± 0.036
2.135AsnArg: 2.135 ± 0.029
5.409AsnSer: 5.409 ± 0.072
3.679AsnThr: 3.679 ± 0.053
3.194AsnVal: 3.194 ± 0.036
0.599AsnTrp: 0.599 ± 0.015
2.249AsnTyr: 2.249 ± 0.031
0.0AsnXaa: 0.0 ± 0.0
Pro
2.429ProAla: 2.429 ± 0.035
0.306ProCys: 0.306 ± 0.011
1.937ProAsp: 1.937 ± 0.029
2.774ProGlu: 2.774 ± 0.042
1.808ProPhe: 1.808 ± 0.03
1.902ProGly: 1.902 ± 0.029
1.094ProHis: 1.094 ± 0.023
2.767ProIle: 2.767 ± 0.032
2.815ProLys: 2.815 ± 0.041
4.162ProLeu: 4.162 ± 0.044
0.767ProMet: 0.767 ± 0.016
2.367ProAsn: 2.367 ± 0.031
2.996ProPro: 2.996 ± 0.081
2.48ProGln: 2.48 ± 0.05
1.698ProArg: 1.698 ± 0.03
3.996ProSer: 3.996 ± 0.051
3.005ProThr: 3.005 ± 0.06
2.616ProVal: 2.616 ± 0.045
0.348ProTrp: 0.348 ± 0.011
1.32ProTyr: 1.32 ± 0.023
0.0ProXaa: 0.0 ± 0.0
Gln
2.389GlnAla: 2.389 ± 0.034
0.397GlnCys: 0.397 ± 0.013
2.082GlnAsp: 2.082 ± 0.031
2.929GlnGlu: 2.929 ± 0.038
1.916GlnPhe: 1.916 ± 0.024
1.985GlnGly: 1.985 ± 0.032
1.463GlnHis: 1.463 ± 0.032
2.603GlnIle: 2.603 ± 0.033
2.827GlnLys: 2.827 ± 0.036
4.893GlnLeu: 4.893 ± 0.057
0.877GlnMet: 0.877 ± 0.022
2.618GlnAsn: 2.618 ± 0.036
2.265GlnPro: 2.265 ± 0.047
6.546GlnGln: 6.546 ± 0.183
2.011GlnArg: 2.011 ± 0.033
3.52GlnSer: 3.52 ± 0.051
2.391GlnThr: 2.391 ± 0.032
2.31GlnVal: 2.31 ± 0.028
0.359GlnTrp: 0.359 ± 0.011
1.558GlnTyr: 1.558 ± 0.027
0.0GlnXaa: 0.0 ± 0.0
Arg
2.361ArgAla: 2.361 ± 0.034
0.467ArgCys: 0.467 ± 0.014
2.397ArgAsp: 2.397 ± 0.034
2.768ArgGlu: 2.768 ± 0.04
1.795ArgPhe: 1.795 ± 0.025
2.171ArgGly: 2.171 ± 0.036
0.996ArgHis: 0.996 ± 0.019
2.609ArgIle: 2.609 ± 0.029
3.446ArgLys: 3.446 ± 0.043
4.071ArgLeu: 4.071 ± 0.046
0.821ArgMet: 0.821 ± 0.016
2.489ArgAsn: 2.489 ± 0.03
1.621ArgPro: 1.621 ± 0.028
1.908ArgGln: 1.908 ± 0.029
2.564ArgArg: 2.564 ± 0.034
3.206ArgSer: 3.206 ± 0.038
2.129ArgThr: 2.129 ± 0.03
2.23ArgVal: 2.23 ± 0.031
0.399ArgTrp: 0.399 ± 0.013
1.445ArgTyr: 1.445 ± 0.025
0.0ArgXaa: 0.0 ± 0.0
Ser
4.862SerAla: 4.862 ± 0.05
0.777SerCys: 0.777 ± 0.02
4.021SerAsp: 4.021 ± 0.045
4.273SerGlu: 4.273 ± 0.055
3.625SerPhe: 3.625 ± 0.044
4.632SerGly: 4.632 ± 0.06
1.911SerHis: 1.911 ± 0.031
5.462SerIle: 5.462 ± 0.056
5.723SerLys: 5.723 ± 0.055
8.058SerLeu: 8.058 ± 0.069
1.595SerMet: 1.595 ± 0.032
5.526SerAsn: 5.526 ± 0.061
3.883SerPro: 3.883 ± 0.055
3.674SerGln: 3.674 ± 0.046
3.61SerArg: 3.61 ± 0.044
11.067SerSer: 11.067 ± 0.147
6.294SerThr: 6.294 ± 0.078
4.291SerVal: 4.291 ± 0.06
0.719SerTrp: 0.719 ± 0.017
2.394SerTyr: 2.394 ± 0.035
0.0SerXaa: 0.0 ± 0.0
Thr
3.628ThrAla: 3.628 ± 0.045
0.611ThrCys: 0.611 ± 0.016
2.749ThrAsp: 2.749 ± 0.037
3.148ThrGlu: 3.148 ± 0.05
2.353ThrPhe: 2.353 ± 0.034
3.375ThrGly: 3.375 ± 0.059
1.187ThrHis: 1.187 ± 0.022
3.832ThrIle: 3.832 ± 0.044
4.031ThrLys: 4.031 ± 0.04
5.154ThrLeu: 5.154 ± 0.049
1.085ThrMet: 1.085 ± 0.021
3.863ThrAsn: 3.863 ± 0.063
3.156ThrPro: 3.156 ± 0.04
2.246ThrGln: 2.246 ± 0.034
2.415ThrArg: 2.415 ± 0.033
5.989ThrSer: 5.989 ± 0.079
5.386ThrThr: 5.386 ± 0.119
3.102ThrVal: 3.102 ± 0.042
0.525ThrTrp: 0.525 ± 0.02
1.707ThrTyr: 1.707 ± 0.024
0.0ThrXaa: 0.0 ± 0.0
Val
3.598ValAla: 3.598 ± 0.042
0.673ValCys: 0.673 ± 0.015
3.674ValAsp: 3.674 ± 0.04
3.941ValGlu: 3.941 ± 0.05
2.469ValPhe: 2.469 ± 0.029
3.309ValGly: 3.309 ± 0.059
1.188ValHis: 1.188 ± 0.02
3.339ValIle: 3.339 ± 0.042
3.884ValLys: 3.884 ± 0.044
5.347ValLeu: 5.347 ± 0.051
1.124ValMet: 1.124 ± 0.025
3.063ValAsn: 3.063 ± 0.03
2.665ValPro: 2.665 ± 0.039
2.172ValGln: 2.172 ± 0.027
2.201ValArg: 2.201 ± 0.027
4.503ValSer: 4.503 ± 0.05
3.076ValThr: 3.076 ± 0.046
3.949ValVal: 3.949 ± 0.092
0.56ValTrp: 0.56 ± 0.015
1.88ValTyr: 1.88 ± 0.026
0.0ValXaa: 0.0 ± 0.0
Trp
0.467TrpAla: 0.467 ± 0.014
0.194TrpCys: 0.194 ± 0.009
0.562TrpAsp: 0.562 ± 0.018
0.492TrpGlu: 0.492 ± 0.013
0.524TrpPhe: 0.524 ± 0.015
0.506TrpGly: 0.506 ± 0.016
0.193TrpHis: 0.193 ± 0.009
0.6TrpIle: 0.6 ± 0.015
0.688TrpLys: 0.688 ± 0.017
0.934TrpLeu: 0.934 ± 0.021
0.205TrpMet: 0.205 ± 0.01
0.546TrpAsn: 0.546 ± 0.015
0.285TrpPro: 0.285 ± 0.011
0.335TrpGln: 0.335 ± 0.011
0.463TrpArg: 0.463 ± 0.013
0.738TrpSer: 0.738 ± 0.016
0.542TrpThr: 0.542 ± 0.018
0.534TrpVal: 0.534 ± 0.016
0.158TrpTrp: 0.158 ± 0.008
0.353TrpTyr: 0.353 ± 0.012
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.759TyrAla: 1.759 ± 0.026
0.47TyrCys: 0.47 ± 0.014
2.122TyrAsp: 2.122 ± 0.03
2.048TyrGlu: 2.048 ± 0.027
1.574TyrPhe: 1.574 ± 0.024
1.874TyrGly: 1.874 ± 0.032
0.841TyrHis: 0.841 ± 0.02
2.126TyrIle: 2.126 ± 0.031
2.306TyrLys: 2.306 ± 0.029
3.376TyrLeu: 3.376 ± 0.034
0.642TyrMet: 0.642 ± 0.015
2.107TyrAsn: 2.107 ± 0.03
1.298TyrPro: 1.298 ± 0.021
1.493TyrGln: 1.493 ± 0.025
1.397TyrArg: 1.397 ± 0.027
2.534TyrSer: 2.534 ± 0.036
1.841TyrThr: 1.841 ± 0.031
1.708TyrVal: 1.708 ± 0.027
0.372TyrTrp: 0.372 ± 0.014
1.407TyrTyr: 1.407 ± 0.025
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5779 proteins (2942605 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski