Amino acid dipepetide frequency for Lactiplantibacillus mudanjiangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.237AlaAla: 9.237 ± 0.14	0.401AlaCys: 0.401 ± 0.023	5.694AlaAsp: 5.694 ± 0.083	4.287AlaGlu: 4.287 ± 0.075	3.259AlaPhe: 3.259 ± 0.066	6.648AlaGly: 6.648 ± 0.099	1.821AlaHis: 1.821 ± 0.043	6.131AlaIle: 6.131 ± 0.088	5.692AlaLys: 5.692 ± 0.093	8.896AlaLeu: 8.896 ± 0.108	2.531AlaMet: 2.531 ± 0.053	3.983AlaAsn: 3.983 ± 0.07	2.698AlaPro: 2.698 ± 0.054	4.434AlaGln: 4.434 ± 0.089	2.856AlaArg: 2.856 ± 0.059	4.999AlaSer: 4.999 ± 0.106	7.099AlaThr: 7.099 ± 0.117	6.484AlaVal: 6.484 ± 0.089	0.993AlaTrp: 0.993 ± 0.036	2.935AlaTyr: 2.935 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.327CysAla: 0.327 ± 0.017	0.044CysCys: 0.044 ± 0.007	0.264CysAsp: 0.264 ± 0.016	0.24CysGlu: 0.24 ± 0.016	0.216CysPhe: 0.216 ± 0.015	0.465CysGly: 0.465 ± 0.023	0.14CysHis: 0.14 ± 0.011	0.216CysIle: 0.216 ± 0.015	0.142CysLys: 0.142 ± 0.011	0.577CysLeu: 0.577 ± 0.026	0.102CysMet: 0.102 ± 0.009	0.146CysAsn: 0.146 ± 0.013	0.203CysPro: 0.203 ± 0.017	0.244CysGln: 0.244 ± 0.017	0.201CysArg: 0.201 ± 0.015	0.285CysSer: 0.285 ± 0.016	0.237CysThr: 0.237 ± 0.016	0.32CysVal: 0.32 ± 0.017	0.084CysTrp: 0.084 ± 0.008	0.203CysTyr: 0.203 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.493AspAla: 4.493 ± 0.073	0.283AspCys: 0.283 ± 0.019	3.824AspAsp: 3.824 ± 0.082	3.329AspGlu: 3.329 ± 0.055	2.6AspPhe: 2.6 ± 0.052	3.64AspGly: 3.64 ± 0.079	1.537AspHis: 1.537 ± 0.041	2.996AspIle: 2.996 ± 0.059	2.59AspLys: 2.59 ± 0.054	5.867AspLeu: 5.867 ± 0.09	1.536AspMet: 1.536 ± 0.044	2.333AspAsn: 2.333 ± 0.052	2.281AspPro: 2.281 ± 0.057	3.67AspGln: 3.67 ± 0.07	2.438AspArg: 2.438 ± 0.054	2.745AspSer: 2.745 ± 0.069	3.286AspThr: 3.286 ± 0.102	3.962AspVal: 3.962 ± 0.082	0.833AspTrp: 0.833 ± 0.028	2.599AspTyr: 2.599 ± 0.058	0.0AspXaa: 0.0 ± 0.0
Glu	3.938GluAla: 3.938 ± 0.068	0.183GluCys: 0.183 ± 0.014	2.206GluAsp: 2.206 ± 0.053	1.91GluGlu: 1.91 ± 0.052	1.74GluPhe: 1.74 ± 0.038	2.023GluGly: 2.023 ± 0.046	1.12GluHis: 1.12 ± 0.034	3.01GluIle: 3.01 ± 0.064	2.797GluLys: 2.797 ± 0.058	5.073GluLeu: 5.073 ± 0.087	1.31GluMet: 1.31 ± 0.031	2.136GluAsn: 2.136 ± 0.049	1.754GluPro: 1.754 ± 0.047	2.643GluGln: 2.643 ± 0.058	2.284GluArg: 2.284 ± 0.052	2.261GluSer: 2.261 ± 0.051	3.164GluThr: 3.164 ± 0.062	2.936GluVal: 2.936 ± 0.068	0.463GluTrp: 0.463 ± 0.022	1.279GluTyr: 1.279 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.153PheAla: 3.153 ± 0.063	0.264PheCys: 0.264 ± 0.014	2.9PheAsp: 2.9 ± 0.066	2.024PheGlu: 2.024 ± 0.051	1.713PhePhe: 1.713 ± 0.05	3.165PheGly: 3.165 ± 0.058	0.773PheHis: 0.773 ± 0.029	2.582PheIle: 2.582 ± 0.06	2.502PheLys: 2.502 ± 0.058	3.34PheLeu: 3.34 ± 0.078	1.087PheMet: 1.087 ± 0.035	2.134PheAsn: 2.134 ± 0.045	1.28PhePro: 1.28 ± 0.035	1.45PheGln: 1.45 ± 0.04	1.209PheArg: 1.209 ± 0.034	2.612PheSer: 2.612 ± 0.056	2.489PheThr: 2.489 ± 0.052	2.824PheVal: 2.824 ± 0.057	0.598PheTrp: 0.598 ± 0.027	1.618PheTyr: 1.618 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.005GlyAla: 5.005 ± 0.09	0.42GlyCys: 0.42 ± 0.023	3.54GlyAsp: 3.54 ± 0.075	2.792GlyGlu: 2.792 ± 0.06	2.878GlyPhe: 2.878 ± 0.06	4.279GlyGly: 4.279 ± 0.084	1.596GlyHis: 1.596 ± 0.043	5.01GlyIle: 5.01 ± 0.085	3.858GlyLys: 3.858 ± 0.071	7.301GlyLeu: 7.301 ± 0.102	1.981GlyMet: 1.981 ± 0.049	2.657GlyAsn: 2.657 ± 0.065	1.601GlyPro: 1.601 ± 0.041	3.492GlyGln: 3.492 ± 0.069	2.567GlyArg: 2.567 ± 0.048	3.932GlySer: 3.932 ± 0.077	4.662GlyThr: 4.662 ± 0.087	5.0GlyVal: 5.0 ± 0.081	1.054GlyTrp: 1.054 ± 0.04	2.804GlyTyr: 2.804 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.667HisAla: 1.667 ± 0.037	0.133HisCys: 0.133 ± 0.01	1.471HisAsp: 1.471 ± 0.038	1.087HisGlu: 1.087 ± 0.033	1.026HisPhe: 1.026 ± 0.035	1.718HisGly: 1.718 ± 0.047	0.802HisHis: 0.802 ± 0.031	1.098HisIle: 1.098 ± 0.037	0.801HisLys: 0.801 ± 0.028	2.403HisLeu: 2.403 ± 0.055	0.514HisMet: 0.514 ± 0.022	0.827HisAsn: 0.827 ± 0.027	1.085HisPro: 1.085 ± 0.033	1.496HisGln: 1.496 ± 0.044	1.04HisArg: 1.04 ± 0.037	1.074HisSer: 1.074 ± 0.035	1.189HisThr: 1.189 ± 0.036	1.55HisVal: 1.55 ± 0.039	0.4HisTrp: 0.4 ± 0.019	1.156HisTyr: 1.156 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.84IleAla: 5.84 ± 0.077	0.377IleCys: 0.377 ± 0.02	4.019IleAsp: 4.019 ± 0.067	3.024IleGlu: 3.024 ± 0.06	2.59IlePhe: 2.59 ± 0.06	5.106IleGly: 5.106 ± 0.092	1.237IleHis: 1.237 ± 0.037	4.196IleIle: 4.196 ± 0.081	3.729IleLys: 3.729 ± 0.072	5.684IleLeu: 5.684 ± 0.102	1.577IleMet: 1.577 ± 0.042	3.09IleAsn: 3.09 ± 0.064	2.359IlePro: 2.359 ± 0.051	2.61IleGln: 2.61 ± 0.056	2.332IleArg: 2.332 ± 0.046	3.88IleSer: 3.88 ± 0.075	4.459IleThr: 4.459 ± 0.077	4.8IleVal: 4.8 ± 0.092	0.651IleTrp: 0.651 ± 0.024	2.055IleTyr: 2.055 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	5.136LysAla: 5.136 ± 0.079	0.133LysCys: 0.133 ± 0.012	2.69LysAsp: 2.69 ± 0.069	2.227LysGlu: 2.227 ± 0.05	1.758LysPhe: 1.758 ± 0.044	2.809LysGly: 2.809 ± 0.065	1.194LysHis: 1.194 ± 0.032	3.415LysIle: 3.415 ± 0.06	3.757LysLys: 3.757 ± 0.114	5.564LysLeu: 5.564 ± 0.097	1.792LysMet: 1.792 ± 0.042	2.485LysAsn: 2.485 ± 0.067	2.163LysPro: 2.163 ± 0.051	3.465LysGln: 3.465 ± 0.084	2.828LysArg: 2.828 ± 0.053	3.25LysSer: 3.25 ± 0.077	4.368LysThr: 4.368 ± 0.08	3.966LysVal: 3.966 ± 0.076	0.645LysTrp: 0.645 ± 0.025	2.045LysTyr: 2.045 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	10.769LeuAla: 10.769 ± 0.115	0.486LeuCys: 0.486 ± 0.022	5.353LeuAsp: 5.353 ± 0.093	3.577LeuGlu: 3.577 ± 0.066	3.812LeuPhe: 3.812 ± 0.083	6.893LeuGly: 6.893 ± 0.094	1.751LeuHis: 1.751 ± 0.04	6.935LeuIle: 6.935 ± 0.119	6.082LeuLys: 6.082 ± 0.091	9.601LeuLeu: 9.601 ± 0.144	2.835LeuMet: 2.835 ± 0.066	4.738LeuAsn: 4.738 ± 0.079	4.41LeuPro: 4.41 ± 0.089	4.328LeuGln: 4.328 ± 0.08	3.732LeuArg: 3.732 ± 0.075	6.383LeuSer: 6.383 ± 0.075	8.799LeuThr: 8.799 ± 0.123	7.436LeuVal: 7.436 ± 0.118	0.966LeuTrp: 0.966 ± 0.034	2.706LeuTyr: 2.706 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	2.797MetAla: 2.797 ± 0.057	0.102MetCys: 0.102 ± 0.01	1.179MetAsp: 1.179 ± 0.036	0.867MetGlu: 0.867 ± 0.031	0.978MetPhe: 0.978 ± 0.044	1.694MetGly: 1.694 ± 0.045	0.525MetHis: 0.525 ± 0.023	1.931MetIle: 1.931 ± 0.049	1.537MetLys: 1.537 ± 0.042	2.452MetLeu: 2.452 ± 0.059	0.786MetMet: 0.786 ± 0.03	1.215MetAsn: 1.215 ± 0.032	1.205MetPro: 1.205 ± 0.037	1.421MetGln: 1.421 ± 0.036	1.1MetArg: 1.1 ± 0.03	1.688MetSer: 1.688 ± 0.044	2.36MetThr: 2.36 ± 0.051	1.84MetVal: 1.84 ± 0.047	0.248MetTrp: 0.248 ± 0.017	0.64MetTyr: 0.64 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.491AsnAla: 3.491 ± 0.065	0.204AsnCys: 0.204 ± 0.018	2.506AsnAsp: 2.506 ± 0.057	2.133AsnGlu: 2.133 ± 0.044	1.812AsnPhe: 1.812 ± 0.039	3.446AsnGly: 3.446 ± 0.062	1.149AsnHis: 1.149 ± 0.032	2.438AsnIle: 2.438 ± 0.049	2.061AsnLys: 2.061 ± 0.055	4.175AsnLeu: 4.175 ± 0.059	1.198AsnMet: 1.198 ± 0.034	1.972AsnAsn: 1.972 ± 0.056	1.996AsnPro: 1.996 ± 0.047	2.778AsnGln: 2.778 ± 0.053	1.98AsnArg: 1.98 ± 0.046	2.328AsnSer: 2.328 ± 0.063	2.649AsnThr: 2.649 ± 0.062	3.071AsnVal: 3.071 ± 0.064	0.692AsnTrp: 0.692 ± 0.031	1.745AsnTyr: 1.745 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	3.786ProAla: 3.786 ± 0.063	0.116ProCys: 0.116 ± 0.011	2.384ProAsp: 2.384 ± 0.057	2.281ProGlu: 2.281 ± 0.052	1.582ProPhe: 1.582 ± 0.043	2.149ProGly: 2.149 ± 0.051	0.744ProHis: 0.744 ± 0.029	2.443ProIle: 2.443 ± 0.049	2.182ProLys: 2.182 ± 0.048	3.601ProLeu: 3.601 ± 0.071	0.91ProMet: 0.91 ± 0.03	1.655ProAsn: 1.655 ± 0.048	0.567ProPro: 0.567 ± 0.024	1.739ProGln: 1.739 ± 0.048	1.125ProArg: 1.125 ± 0.037	1.936ProSer: 1.936 ± 0.043	3.243ProThr: 3.243 ± 0.07	3.167ProVal: 3.167 ± 0.066	0.43ProTrp: 0.43 ± 0.021	1.249ProTyr: 1.249 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.828GlnAla: 5.828 ± 0.1	0.15GlnCys: 0.15 ± 0.014	2.086GlnAsp: 2.086 ± 0.047	1.707GlnGlu: 1.707 ± 0.041	1.9GlnPhe: 1.9 ± 0.045	2.519GlnGly: 2.519 ± 0.055	1.448GlnHis: 1.448 ± 0.038	2.998GlnIle: 2.998 ± 0.056	2.529GlnLys: 2.529 ± 0.058	6.862GlnLeu: 6.862 ± 0.117	1.197GlnMet: 1.197 ± 0.034	1.912GlnAsn: 1.912 ± 0.052	2.305GlnPro: 2.305 ± 0.058	3.854GlnGln: 3.854 ± 0.097	2.637GlnArg: 2.637 ± 0.067	2.669GlnSer: 2.669 ± 0.045	4.035GlnThr: 4.035 ± 0.075	4.25GlnVal: 4.25 ± 0.085	0.589GlnTrp: 0.589 ± 0.027	1.76GlnTyr: 1.76 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	2.911ArgAla: 2.911 ± 0.057	0.195ArgCys: 0.195 ± 0.015	2.188ArgAsp: 2.188 ± 0.052	1.974ArgGlu: 1.974 ± 0.052	1.761ArgPhe: 1.761 ± 0.04	2.139ArgGly: 2.139 ± 0.047	1.157ArgHis: 1.157 ± 0.034	2.45ArgIle: 2.45 ± 0.058	1.981ArgLys: 1.981 ± 0.057	4.615ArgLeu: 4.615 ± 0.084	0.988ArgMet: 0.988 ± 0.031	1.669ArgAsn: 1.669 ± 0.045	1.579ArgPro: 1.579 ± 0.044	2.945ArgGln: 2.945 ± 0.064	2.118ArgArg: 2.118 ± 0.052	1.901ArgSer: 1.901 ± 0.046	2.24ArgThr: 2.24 ± 0.046	2.758ArgVal: 2.758 ± 0.061	0.533ArgTrp: 0.533 ± 0.023	1.803ArgTyr: 1.803 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.978SerAla: 4.978 ± 0.096	0.23SerCys: 0.23 ± 0.015	3.246SerAsp: 3.246 ± 0.063	2.689SerGlu: 2.689 ± 0.057	2.446SerPhe: 2.446 ± 0.052	4.405SerGly: 4.405 ± 0.097	1.318SerHis: 1.318 ± 0.033	3.45SerIle: 3.45 ± 0.058	3.123SerLys: 3.123 ± 0.079	5.852SerLeu: 5.852 ± 0.076	1.475SerMet: 1.475 ± 0.035	2.473SerAsn: 2.473 ± 0.066	1.744SerPro: 1.744 ± 0.039	3.006SerGln: 3.006 ± 0.066	2.311SerArg: 2.311 ± 0.048	3.928SerSer: 3.928 ± 0.136	4.067SerThr: 4.067 ± 0.092	3.915SerVal: 3.915 ± 0.069	0.801SerTrp: 0.801 ± 0.029	2.215SerTyr: 2.215 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	7.143ThrAla: 7.143 ± 0.115	0.263ThrCys: 0.263 ± 0.018	4.329ThrAsp: 4.329 ± 0.093	3.134ThrGlu: 3.134 ± 0.061	2.705ThrPhe: 2.705 ± 0.051	5.216ThrGly: 5.216 ± 0.083	1.374ThrHis: 1.374 ± 0.034	4.801ThrIle: 4.801 ± 0.085	4.339ThrLys: 4.339 ± 0.089	7.009ThrLeu: 7.009 ± 0.106	1.713ThrMet: 1.713 ± 0.044	3.225ThrAsn: 3.225 ± 0.068	3.3ThrPro: 3.3 ± 0.067	2.975ThrGln: 2.975 ± 0.064	2.162ThrArg: 2.162 ± 0.048	4.624ThrSer: 4.624 ± 0.119	6.81ThrThr: 6.81 ± 0.163	5.789ThrVal: 5.789 ± 0.112	0.856ThrTrp: 0.856 ± 0.038	2.618ThrTyr: 2.618 ± 0.076	0.0ThrXaa: 0.0 ± 0.0
Val	7.065ValAla: 7.065 ± 0.103	0.384ValCys: 0.384 ± 0.022	4.254ValAsp: 4.254 ± 0.083	3.005ValGlu: 3.005 ± 0.062	2.629ValPhe: 2.629 ± 0.062	4.94ValGly: 4.94 ± 0.086	1.377ValHis: 1.377 ± 0.037	5.104ValIle: 5.104 ± 0.085	4.264ValLys: 4.264 ± 0.078	6.845ValLeu: 6.845 ± 0.112	1.974ValMet: 1.974 ± 0.051	3.271ValAsn: 3.271 ± 0.055	2.937ValPro: 2.937 ± 0.057	2.961ValGln: 2.961 ± 0.059	2.409ValArg: 2.409 ± 0.055	4.52ValSer: 4.52 ± 0.079	6.245ValThr: 6.245 ± 0.121	5.561ValVal: 5.561 ± 0.092	0.749ValTrp: 0.749 ± 0.024	2.205ValTyr: 2.205 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.809TrpAla: 0.809 ± 0.029	0.074TrpCys: 0.074 ± 0.009	0.585TrpAsp: 0.585 ± 0.03	0.424TrpGlu: 0.424 ± 0.023	0.569TrpPhe: 0.569 ± 0.024	0.775TrpGly: 0.775 ± 0.032	0.414TrpHis: 0.414 ± 0.022	0.7TrpIle: 0.7 ± 0.028	0.389TrpLys: 0.389 ± 0.021	1.928TrpLeu: 1.928 ± 0.059	0.275TrpMet: 0.275 ± 0.018	0.472TrpAsn: 0.472 ± 0.027	0.364TrpPro: 0.364 ± 0.018	1.001TrpGln: 1.001 ± 0.033	0.652TrpArg: 0.652 ± 0.027	0.755TrpSer: 0.755 ± 0.035	0.707TrpThr: 0.707 ± 0.031	0.786TrpVal: 0.786 ± 0.029	0.252TrpTrp: 0.252 ± 0.016	0.457TrpTyr: 0.457 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.707TyrAla: 2.707 ± 0.058	0.214TyrCys: 0.214 ± 0.015	2.125TyrAsp: 2.125 ± 0.055	1.517TyrGlu: 1.517 ± 0.036	1.743TyrPhe: 1.743 ± 0.041	2.399TyrGly: 2.399 ± 0.054	1.06TyrHis: 1.06 ± 0.039	1.711TyrIle: 1.711 ± 0.045	1.335TyrLys: 1.335 ± 0.041	3.951TyrLeu: 3.951 ± 0.075	0.78TyrMet: 0.78 ± 0.028	1.432TyrAsn: 1.432 ± 0.045	1.456TyrPro: 1.456 ± 0.039	2.724TyrGln: 2.724 ± 0.061	1.924TyrArg: 1.924 ± 0.051	1.904TyrSer: 1.904 ± 0.05	2.275TyrThr: 2.275 ± 0.072	2.282TyrVal: 2.282 ± 0.045	0.552TyrTrp: 0.552 ± 0.025	1.555TyrTyr: 1.555 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3503 proteins (1003855 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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