Amino acid dipepetide frequency for Endozoicomonas elysicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.152AlaAla: 7.152 ± 0.101	1.095AlaCys: 1.095 ± 0.029	4.4AlaAsp: 4.4 ± 0.08	5.289AlaGlu: 5.289 ± 0.076	3.281AlaPhe: 3.281 ± 0.051	6.632AlaGly: 6.632 ± 0.099	1.59AlaHis: 1.59 ± 0.037	5.617AlaIle: 5.617 ± 0.067	3.55AlaLys: 3.55 ± 0.06	8.992AlaLeu: 8.992 ± 0.102	2.699AlaMet: 2.699 ± 0.057	2.923AlaAsn: 2.923 ± 0.056	2.971AlaPro: 2.971 ± 0.049	2.933AlaGln: 2.933 ± 0.05	4.283AlaArg: 4.283 ± 0.073	5.576AlaSer: 5.576 ± 0.073	4.182AlaThr: 4.182 ± 0.081	5.641AlaVal: 5.641 ± 0.078	0.957AlaTrp: 0.957 ± 0.03	2.201AlaTyr: 2.201 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.78CysAla: 0.78 ± 0.025	0.193CysCys: 0.193 ± 0.012	0.62CysAsp: 0.62 ± 0.022	0.614CysGlu: 0.614 ± 0.022	0.504CysPhe: 0.504 ± 0.02	0.855CysGly: 0.855 ± 0.028	0.363CysHis: 0.363 ± 0.018	0.675CysIle: 0.675 ± 0.024	0.477CysLys: 0.477 ± 0.019	1.148CysLeu: 1.148 ± 0.031	0.258CysMet: 0.258 ± 0.013	0.431CysAsn: 0.431 ± 0.019	0.507CysPro: 0.507 ± 0.022	0.541CysGln: 0.541 ± 0.023	0.647CysArg: 0.647 ± 0.024	0.869CysSer: 0.869 ± 0.024	0.516CysThr: 0.516 ± 0.017	0.646CysVal: 0.646 ± 0.022	0.145CysTrp: 0.145 ± 0.011	0.392CysTyr: 0.392 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.185AspAla: 4.185 ± 0.068	0.608AspCys: 0.608 ± 0.023	3.195AspAsp: 3.195 ± 0.086	3.656AspGlu: 3.656 ± 0.054	2.429AspPhe: 2.429 ± 0.047	4.168AspGly: 4.168 ± 0.114	1.442AspHis: 1.442 ± 0.035	3.967AspIle: 3.967 ± 0.061	2.697AspLys: 2.697 ± 0.053	5.397AspLeu: 5.397 ± 0.08	1.383AspMet: 1.383 ± 0.034	2.449AspAsn: 2.449 ± 0.066	2.321AspPro: 2.321 ± 0.045	2.674AspGln: 2.674 ± 0.049	2.857AspArg: 2.857 ± 0.051	3.739AspSer: 3.739 ± 0.07	3.089AspThr: 3.089 ± 0.22	3.564AspVal: 3.564 ± 0.062	0.77AspTrp: 0.77 ± 0.024	2.016AspTyr: 2.016 ± 0.047	0.001AspXaa: 0.001 ± 0.001
Glu	5.581GluAla: 5.581 ± 0.065	0.576GluCys: 0.576 ± 0.025	3.04GluAsp: 3.04 ± 0.056	4.156GluGlu: 4.156 ± 0.077	2.133GluPhe: 2.133 ± 0.043	4.134GluGly: 4.134 ± 0.071	1.578GluHis: 1.578 ± 0.037	3.688GluIle: 3.688 ± 0.057	4.093GluLys: 4.093 ± 0.072	6.878GluLeu: 6.878 ± 0.086	1.621GluMet: 1.621 ± 0.035	2.848GluAsn: 2.848 ± 0.055	2.365GluPro: 2.365 ± 0.047	3.634GluGln: 3.634 ± 0.069	3.381GluArg: 3.381 ± 0.059	4.141GluSer: 4.141 ± 0.057	3.3GluThr: 3.3 ± 0.053	4.262GluVal: 4.262 ± 0.072	0.744GluTrp: 0.744 ± 0.024	1.81GluTyr: 1.81 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	2.997PheAla: 2.997 ± 0.049	0.507PheCys: 0.507 ± 0.02	2.559PheAsp: 2.559 ± 0.049	2.32PheGlu: 2.32 ± 0.041	1.753PhePhe: 1.753 ± 0.04	3.04PheGly: 3.04 ± 0.053	0.855PheHis: 0.855 ± 0.023	2.528PheIle: 2.528 ± 0.047	1.806PheLys: 1.806 ± 0.037	3.634PheLeu: 3.634 ± 0.064	1.085PheMet: 1.085 ± 0.028	1.853PheAsn: 1.853 ± 0.04	1.571PhePro: 1.571 ± 0.038	1.527PheGln: 1.527 ± 0.035	1.827PheArg: 1.827 ± 0.033	3.398PheSer: 3.398 ± 0.061	2.255PheThr: 2.255 ± 0.064	2.326PheVal: 2.326 ± 0.052	0.542PheTrp: 0.542 ± 0.02	1.338PheTyr: 1.338 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.621GlyAla: 5.621 ± 0.093	0.986GlyCys: 0.986 ± 0.032	4.007GlyAsp: 4.007 ± 0.166	4.347GlyGlu: 4.347 ± 0.056	3.378GlyPhe: 3.378 ± 0.059	5.56GlyGly: 5.56 ± 0.229	1.658GlyHis: 1.658 ± 0.044	4.894GlyIle: 4.894 ± 0.065	3.919GlyLys: 3.919 ± 0.057	7.26GlyLeu: 7.26 ± 0.09	2.149GlyMet: 2.149 ± 0.043	3.084GlyAsn: 3.084 ± 0.111	1.833GlyPro: 1.833 ± 0.038	3.017GlyGln: 3.017 ± 0.053	3.465GlyArg: 3.465 ± 0.057	5.175GlySer: 5.175 ± 0.114	3.746GlyThr: 3.746 ± 0.104	5.257GlyVal: 5.257 ± 0.066	1.037GlyTrp: 1.037 ± 0.029	2.606GlyTyr: 2.606 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	1.478HisAla: 1.478 ± 0.038	0.379HisCys: 0.379 ± 0.017	1.167HisAsp: 1.167 ± 0.031	1.234HisGlu: 1.234 ± 0.03	1.137HisPhe: 1.137 ± 0.031	1.639HisGly: 1.639 ± 0.04	0.754HisHis: 0.754 ± 0.025	1.396HisIle: 1.396 ± 0.035	1.026HisLys: 1.026 ± 0.027	2.269HisLeu: 2.269 ± 0.039	0.6HisMet: 0.6 ± 0.021	0.897HisAsn: 0.897 ± 0.027	1.29HisPro: 1.29 ± 0.037	1.235HisGln: 1.235 ± 0.033	1.233HisArg: 1.233 ± 0.03	1.529HisSer: 1.529 ± 0.035	1.116HisThr: 1.116 ± 0.03	1.114HisVal: 1.114 ± 0.03	0.374HisTrp: 0.374 ± 0.016	0.849HisTyr: 0.849 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.599IleAla: 5.599 ± 0.079	0.705IleCys: 0.705 ± 0.021	3.975IleAsp: 3.975 ± 0.053	4.169IleGlu: 4.169 ± 0.066	2.143IlePhe: 2.143 ± 0.041	4.324IleGly: 4.324 ± 0.057	1.438IleHis: 1.438 ± 0.036	3.663IleIle: 3.663 ± 0.06	3.092IleLys: 3.092 ± 0.057	5.377IleLeu: 5.377 ± 0.074	1.33IleMet: 1.33 ± 0.032	3.125IleAsn: 3.125 ± 0.057	3.075IlePro: 3.075 ± 0.054	2.327IleGln: 2.327 ± 0.043	3.209IleArg: 3.209 ± 0.043	4.51IleSer: 4.51 ± 0.075	3.914IleThr: 3.914 ± 0.081	3.528IleVal: 3.528 ± 0.051	0.632IleTrp: 0.632 ± 0.022	1.74IleTyr: 1.74 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.736LysAla: 4.736 ± 0.081	0.349LysCys: 0.349 ± 0.017	2.672LysAsp: 2.672 ± 0.045	3.407LysGlu: 3.407 ± 0.065	1.288LysPhe: 1.288 ± 0.03	3.335LysGly: 3.335 ± 0.052	1.105LysHis: 1.105 ± 0.033	2.691LysIle: 2.691 ± 0.052	3.173LysLys: 3.173 ± 0.071	4.781LysLeu: 4.781 ± 0.074	1.299LysMet: 1.299 ± 0.034	2.136LysAsn: 2.136 ± 0.044	2.482LysPro: 2.482 ± 0.049	2.373LysGln: 2.373 ± 0.049	2.491LysArg: 2.491 ± 0.048	3.18LysSer: 3.18 ± 0.062	2.876LysThr: 2.876 ± 0.053	3.595LysVal: 3.595 ± 0.054	0.487LysTrp: 0.487 ± 0.02	1.335LysTyr: 1.335 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	8.986LeuAla: 8.986 ± 0.101	1.184LeuCys: 1.184 ± 0.027	5.768LeuAsp: 5.768 ± 0.077	6.375LeuGlu: 6.375 ± 0.078	4.155LeuPhe: 4.155 ± 0.072	6.857LeuGly: 6.857 ± 0.08	2.021LeuHis: 2.021 ± 0.04	6.144LeuIle: 6.144 ± 0.079	5.816LeuLys: 5.816 ± 0.086	10.277LeuLeu: 10.277 ± 0.14	2.875LeuMet: 2.875 ± 0.057	4.47LeuAsn: 4.47 ± 0.065	5.066LeuPro: 5.066 ± 0.08	3.878LeuGln: 3.878 ± 0.058	4.645LeuArg: 4.645 ± 0.064	7.945LeuSer: 7.945 ± 0.088	5.887LeuThr: 5.887 ± 0.08	6.603LeuVal: 6.603 ± 0.096	1.085LeuTrp: 1.085 ± 0.031	2.548LeuTyr: 2.548 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.661MetAla: 2.661 ± 0.055	0.198MetCys: 0.198 ± 0.011	1.567MetAsp: 1.567 ± 0.04	1.582MetGlu: 1.582 ± 0.033	0.825MetPhe: 0.825 ± 0.026	2.062MetGly: 2.062 ± 0.043	0.518MetHis: 0.518 ± 0.021	1.58MetIle: 1.58 ± 0.035	1.464MetLys: 1.464 ± 0.036	2.65MetLeu: 2.65 ± 0.047	0.824MetMet: 0.824 ± 0.028	1.153MetAsn: 1.153 ± 0.024	1.363MetPro: 1.363 ± 0.031	0.931MetGln: 0.931 ± 0.028	1.066MetArg: 1.066 ± 0.031	1.884MetSer: 1.884 ± 0.042	1.722MetThr: 1.722 ± 0.033	1.998MetVal: 1.998 ± 0.038	0.177MetTrp: 0.177 ± 0.011	0.503MetTyr: 0.503 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.018AsnAla: 3.018 ± 0.054	0.445AsnCys: 0.445 ± 0.018	2.488AsnAsp: 2.488 ± 0.118	2.276AsnGlu: 2.276 ± 0.045	1.381AsnPhe: 1.381 ± 0.031	3.163AsnGly: 3.163 ± 0.087	1.08AsnHis: 1.08 ± 0.029	2.812AsnIle: 2.812 ± 0.053	1.953AsnLys: 1.953 ± 0.047	3.92AsnLeu: 3.92 ± 0.063	0.949AsnMet: 0.949 ± 0.029	1.985AsnAsn: 1.985 ± 0.059	2.436AsnPro: 2.436 ± 0.046	1.948AsnGln: 1.948 ± 0.045	2.181AsnArg: 2.181 ± 0.041	2.703AsnSer: 2.703 ± 0.058	2.395AsnThr: 2.395 ± 0.057	2.262AsnVal: 2.262 ± 0.052	0.54AsnTrp: 0.54 ± 0.022	1.302AsnTyr: 1.302 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	3.605ProAla: 3.605 ± 0.065	0.368ProCys: 0.368 ± 0.014	3.132ProAsp: 3.132 ± 0.049	4.279ProGlu: 4.279 ± 0.062	1.798ProPhe: 1.798 ± 0.035	3.274ProGly: 3.274 ± 0.066	0.878ProHis: 0.878 ± 0.027	2.159ProIle: 2.159 ± 0.046	1.811ProLys: 1.811 ± 0.041	4.32ProLeu: 4.32 ± 0.065	1.135ProMet: 1.135 ± 0.027	1.371ProAsn: 1.371 ± 0.037	1.603ProPro: 1.603 ± 0.045	1.444ProGln: 1.444 ± 0.032	1.55ProArg: 1.55 ± 0.036	2.821ProSer: 2.821 ± 0.049	1.928ProThr: 1.928 ± 0.042	3.916ProVal: 3.916 ± 0.057	0.565ProTrp: 0.565 ± 0.024	1.254ProTyr: 1.254 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.774GlnAla: 3.774 ± 0.055	0.464GlnCys: 0.464 ± 0.018	1.902GlnAsp: 1.902 ± 0.04	2.616GlnGlu: 2.616 ± 0.049	1.611GlnPhe: 1.611 ± 0.038	2.835GlnGly: 2.835 ± 0.044	0.989GlnHis: 0.989 ± 0.029	2.281GlnIle: 2.281 ± 0.046	2.311GlnLys: 2.311 ± 0.051	4.99GlnLeu: 4.99 ± 0.079	1.053GlnMet: 1.053 ± 0.025	1.614GlnAsn: 1.614 ± 0.039	1.983GlnPro: 1.983 ± 0.048	2.615GlnGln: 2.615 ± 0.068	2.214GlnArg: 2.214 ± 0.044	2.78GlnSer: 2.78 ± 0.05	2.068GlnThr: 2.068 ± 0.038	2.975GlnVal: 2.975 ± 0.062	0.777GlnTrp: 0.777 ± 0.026	1.309GlnTyr: 1.309 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	3.473ArgAla: 3.473 ± 0.059	0.516ArgCys: 0.516 ± 0.021	2.609ArgAsp: 2.609 ± 0.046	3.44ArgGlu: 3.44 ± 0.063	2.361ArgPhe: 2.361 ± 0.039	2.817ArgGly: 2.817 ± 0.056	1.255ArgHis: 1.255 ± 0.031	3.129ArgIle: 3.129 ± 0.051	2.785ArgLys: 2.785 ± 0.049	5.381ArgLeu: 5.381 ± 0.079	1.325ArgMet: 1.325 ± 0.03	1.963ArgAsn: 1.963 ± 0.038	1.975ArgPro: 1.975 ± 0.041	2.531ArgGln: 2.531 ± 0.046	2.597ArgArg: 2.597 ± 0.056	3.079ArgSer: 3.079 ± 0.052	2.32ArgThr: 2.32 ± 0.045	3.392ArgVal: 3.392 ± 0.059	0.662ArgTrp: 0.662 ± 0.025	1.789ArgTyr: 1.789 ± 0.04	0.001ArgXaa: 0.001 ± 0.001
Ser	5.332SerAla: 5.332 ± 0.073	0.75SerCys: 0.75 ± 0.028	4.151SerAsp: 4.151 ± 0.081	4.57SerGlu: 4.57 ± 0.068	2.868SerPhe: 2.868 ± 0.046	6.118SerGly: 6.118 ± 0.108	1.558SerHis: 1.558 ± 0.037	4.316SerIle: 4.316 ± 0.06	2.991SerLys: 2.991 ± 0.05	7.401SerLeu: 7.401 ± 0.087	1.826SerMet: 1.826 ± 0.036	2.663SerAsn: 2.663 ± 0.064	3.0SerPro: 3.0 ± 0.056	2.834SerGln: 2.834 ± 0.06	3.518SerArg: 3.518 ± 0.048	5.298SerSer: 5.298 ± 0.094	3.561SerThr: 3.561 ± 0.076	4.51SerVal: 4.51 ± 0.066	0.939SerTrp: 0.939 ± 0.03	1.953SerTyr: 1.953 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.613ThrAla: 4.613 ± 0.094	0.533ThrCys: 0.533 ± 0.022	3.094ThrAsp: 3.094 ± 0.084	3.142ThrGlu: 3.142 ± 0.049	2.06ThrPhe: 2.06 ± 0.04	4.808ThrGly: 4.808 ± 0.112	1.177ThrHis: 1.177 ± 0.03	3.445ThrIle: 3.445 ± 0.08	1.807ThrLys: 1.807 ± 0.042	6.461ThrLeu: 6.461 ± 0.153	1.254ThrMet: 1.254 ± 0.029	1.799ThrAsn: 1.799 ± 0.053	2.861ThrPro: 2.861 ± 0.051	1.908ThrGln: 1.908 ± 0.034	2.574ThrArg: 2.574 ± 0.047	3.606ThrSer: 3.606 ± 0.067	3.092ThrThr: 3.092 ± 0.084	3.955ThrVal: 3.955 ± 0.088	0.595ThrTrp: 0.595 ± 0.023	1.34ThrTyr: 1.34 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	5.633ValAla: 5.633 ± 0.081	0.777ValCys: 0.777 ± 0.021	4.051ValAsp: 4.051 ± 0.063	4.217ValGlu: 4.217 ± 0.061	2.707ValPhe: 2.707 ± 0.047	4.268ValGly: 4.268 ± 0.064	1.345ValHis: 1.345 ± 0.033	4.688ValIle: 4.688 ± 0.057	3.187ValLys: 3.187 ± 0.057	6.445ValLeu: 6.445 ± 0.081	2.095ValMet: 2.095 ± 0.043	2.9ValAsn: 2.9 ± 0.05	2.573ValPro: 2.573 ± 0.056	2.258ValGln: 2.258 ± 0.048	3.196ValArg: 3.196 ± 0.054	5.016ValSer: 5.016 ± 0.072	4.015ValThr: 4.015 ± 0.079	4.917ValVal: 4.917 ± 0.072	0.708ValTrp: 0.708 ± 0.022	1.827ValTyr: 1.827 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.734TrpAla: 0.734 ± 0.027	0.152TrpCys: 0.152 ± 0.012	0.565TrpAsp: 0.565 ± 0.021	0.656TrpGlu: 0.656 ± 0.021	0.552TrpPhe: 0.552 ± 0.021	0.858TrpGly: 0.858 ± 0.03	0.341TrpHis: 0.341 ± 0.018	0.62TrpIle: 0.62 ± 0.021	0.584TrpLys: 0.584 ± 0.021	1.721TrpLeu: 1.721 ± 0.048	0.34TrpMet: 0.34 ± 0.016	0.495TrpAsn: 0.495 ± 0.018	0.499TrpPro: 0.499 ± 0.021	0.84TrpGln: 0.84 ± 0.026	0.655TrpArg: 0.655 ± 0.023	0.816TrpSer: 0.816 ± 0.028	0.547TrpThr: 0.547 ± 0.023	0.814TrpVal: 0.814 ± 0.026	0.162TrpTrp: 0.162 ± 0.012	0.366TrpTyr: 0.366 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.005TyrAla: 2.005 ± 0.046	0.398TyrCys: 0.398 ± 0.018	1.643TyrAsp: 1.643 ± 0.038	1.619TyrGlu: 1.619 ± 0.037	1.361TyrPhe: 1.361 ± 0.035	2.252TyrGly: 2.252 ± 0.046	0.77TyrHis: 0.77 ± 0.028	1.58TyrIle: 1.58 ± 0.036	1.25TyrLys: 1.25 ± 0.032	3.283TyrLeu: 3.283 ± 0.053	0.625TyrMet: 0.625 ± 0.022	1.078TyrAsn: 1.078 ± 0.03	1.435TyrPro: 1.435 ± 0.031	1.712TyrGln: 1.712 ± 0.033	1.81TyrArg: 1.81 ± 0.046	2.092TyrSer: 2.092 ± 0.045	1.595TyrThr: 1.595 ± 0.046	1.551TyrVal: 1.551 ± 0.034	0.418TyrTrp: 0.418 ± 0.018	0.963TyrTyr: 0.963 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4147 proteins (1412327 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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