Legionella londiniensis

Taxonomy: cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Legionellaceae; Legionella

Average proteome isoelectric point is 6.92

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2172 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A0W0VRV5|A0A0W0VRV5_9GAMM CTP synthase OS=Legionella londiniensis OX=45068 GN=pyrG PE=3 SV=1
MM1 pKa = 7.31AAIVSKK7 pKa = 10.92AVFFALPKK15 pKa = 9.27KK16 pKa = 8.69TATATPLNSQNIADD30 pKa = 5.54FIAGGYY36 pKa = 8.2WLFPSTLNDD45 pKa = 3.21QIYY48 pKa = 9.43YY49 pKa = 10.46QIFKK53 pKa = 10.97DD54 pKa = 4.6FALDD58 pKa = 3.58PNGRR62 pKa = 11.84YY63 pKa = 9.41SLEE66 pKa = 4.41LGDD69 pKa = 5.17GVILLSEE76 pKa = 4.25KK77 pKa = 11.03NIDD80 pKa = 3.77LSLILPPTAAGEE92 pKa = 4.1DD93 pKa = 3.73ANPILSYY100 pKa = 11.52VNGSEE105 pKa = 4.22VSSEE109 pKa = 3.93LVFIEE114 pKa = 5.35FINTLGQVEE123 pKa = 4.6VGFDD127 pKa = 3.22TRR129 pKa = 11.84ASFKK133 pKa = 10.6PFAYY137 pKa = 10.28DD138 pKa = 3.96LVPEE142 pKa = 4.29EE143 pKa = 4.23LTTYY147 pKa = 11.03ALRR150 pKa = 11.84FAFPDD155 pKa = 5.01GIISSPSLSVPTIPSAPLIHH175 pKa = 6.74LAADD179 pKa = 3.65TGISNTDD186 pKa = 4.42FITNNGSIIVSGLNPNATWQYY207 pKa = 10.99SVNNGPWITGNGNSFVLPEE226 pKa = 4.09GEE228 pKa = 4.29YY229 pKa = 10.8KK230 pKa = 10.63EE231 pKa = 4.67GAVKK235 pKa = 10.22VRR237 pKa = 11.84QINSEE242 pKa = 4.16GNISNTSSLKK252 pKa = 9.02PTVIDD257 pKa = 3.52TTHH260 pKa = 6.88PEE262 pKa = 3.4INIEE266 pKa = 4.17VNQTTEE272 pKa = 3.96DD273 pKa = 3.65NIVNIRR279 pKa = 11.84EE280 pKa = 4.09AGRR283 pKa = 11.84DD284 pKa = 3.18ITITGTVAGEE294 pKa = 3.99FNEE297 pKa = 4.28GDD299 pKa = 3.76TVTLTVNGKK308 pKa = 8.63EE309 pKa = 4.03FQGAVNAEE317 pKa = 4.18GLFSIAVPGRR327 pKa = 11.84DD328 pKa = 3.15LAADD332 pKa = 3.61ANLTIEE338 pKa = 4.45ASIATEE344 pKa = 3.68DD345 pKa = 3.56RR346 pKa = 11.84AGNKK350 pKa = 8.05ATASTDD356 pKa = 2.83HH357 pKa = 6.79TYY359 pKa = 10.86SINYY363 pKa = 9.26APEE366 pKa = 3.94TMEE369 pKa = 5.06DD370 pKa = 3.45LAHH373 pKa = 6.23VFEE376 pKa = 6.37GDD378 pKa = 3.78DD379 pKa = 4.19LIGSNVLSNDD389 pKa = 3.08TDD391 pKa = 3.81QNSSDD396 pKa = 3.55ILSVSLFSANSNGSGAEE413 pKa = 3.94TANGSNTITTLLGGTVTMNADD434 pKa = 3.01GTYY437 pKa = 9.5TYY439 pKa = 10.8SAPKK443 pKa = 9.96SVNNINGADD452 pKa = 3.74VVDD455 pKa = 3.78SFYY458 pKa = 11.63YY459 pKa = 10.15KK460 pKa = 10.82ASDD463 pKa = 4.35GYY465 pKa = 11.47NEE467 pKa = 4.32SDD469 pKa = 3.1WTKK472 pKa = 9.86VTINIQDD479 pKa = 3.65TSPTANPNEE488 pKa = 4.06ATVAYY493 pKa = 9.33QGSVSGNVTTNDD505 pKa = 4.03LFGQDD510 pKa = 3.32TAQLQSVTYY519 pKa = 10.26NHH521 pKa = 6.16ITYY524 pKa = 9.94DD525 pKa = 3.39QFVNGQLTINAANGVLTIHH544 pKa = 6.81QDD546 pKa = 2.94GTYY549 pKa = 9.3TYY551 pKa = 10.49QSNATLPRR559 pKa = 11.84AEE561 pKa = 4.08ITVGGSGGLSSWDD574 pKa = 3.03GVTLHH579 pKa = 6.49GFYY582 pKa = 10.67LGATEE587 pKa = 4.44PTPNSIGYY595 pKa = 8.7RR596 pKa = 11.84EE597 pKa = 4.38HH598 pKa = 6.47YY599 pKa = 10.01GLYY602 pKa = 9.56INSPGSVDD610 pKa = 3.22NSRR613 pKa = 11.84EE614 pKa = 3.6IDD616 pKa = 3.42SRR618 pKa = 11.84AVGDD622 pKa = 3.65TFKK625 pKa = 10.7TEE627 pKa = 4.23KK628 pKa = 10.32IVVEE632 pKa = 3.91FDD634 pKa = 3.73VNVTEE639 pKa = 4.38VTVGARR645 pKa = 11.84DD646 pKa = 3.85VQNHH650 pKa = 6.67DD651 pKa = 4.07SIHH654 pKa = 6.15WIAYY658 pKa = 9.39DD659 pKa = 3.64EE660 pKa = 4.83NGDD663 pKa = 3.81EE664 pKa = 4.25VATGIFTGEE673 pKa = 3.63NSAPGNDD680 pKa = 3.21HH681 pKa = 7.06TYY683 pKa = 10.27TFTITASEE691 pKa = 4.24AFRR694 pKa = 11.84SVAFMGHH701 pKa = 7.12DD702 pKa = 3.76GNDD705 pKa = 4.47DD706 pKa = 3.52FTLWNIKK713 pKa = 9.46YY714 pKa = 9.93IPAEE718 pKa = 4.22ANQDD722 pKa = 3.48VPPDD726 pKa = 3.29VFTYY730 pKa = 10.97VLVDD734 pKa = 3.62ADD736 pKa = 4.0GSTSQEE742 pKa = 3.75TTLTITHH749 pKa = 7.53DD750 pKa = 3.71STLGTTAVSDD760 pKa = 3.64EE761 pKa = 4.45SSVFEE766 pKa = 4.23SGLPQGTEE774 pKa = 3.53AGIASIVASGNLLANDD790 pKa = 3.81EE791 pKa = 4.48NVTPDD796 pKa = 3.2AAINEE801 pKa = 4.16ISFNGNTFAPVDD813 pKa = 3.81GVITIDD819 pKa = 3.56TPLGILTVYY828 pKa = 10.38TEE830 pKa = 4.89DD831 pKa = 5.07SVDD834 pKa = 3.3GHH836 pKa = 6.29NKK838 pKa = 9.74GDD840 pKa = 3.95YY841 pKa = 10.48EE842 pKa = 4.25YY843 pKa = 10.55TLQNASNEE851 pKa = 3.93GDD853 pKa = 3.59HH854 pKa = 6.93VSEE857 pKa = 4.35AFTYY861 pKa = 10.42QLINSSTGNASSSALTINIADD882 pKa = 4.29DD883 pKa = 3.77APRR886 pKa = 11.84GQDD889 pKa = 2.51IHH891 pKa = 8.24ASLNKK896 pKa = 9.82EE897 pKa = 3.91GSALTINMTLVIDD910 pKa = 4.11VSGSMNEE917 pKa = 3.73IDD919 pKa = 3.94SGEE922 pKa = 4.13TASRR926 pKa = 11.84LEE928 pKa = 3.93LAKK931 pKa = 10.59QSLEE935 pKa = 3.81EE936 pKa = 4.51LIRR939 pKa = 11.84TGDD942 pKa = 3.31EE943 pKa = 3.88AGTINIKK950 pKa = 10.33IIAFSTMAANSGWFVNNIEE969 pKa = 4.69AAIDD973 pKa = 3.81YY974 pKa = 10.83LNLLQANGYY983 pKa = 7.36TYY985 pKa = 11.16YY986 pKa = 11.19DD987 pKa = 3.32NALQEE992 pKa = 4.68VISSNGAPEE1001 pKa = 4.23PSADD1005 pKa = 3.2QHH1007 pKa = 6.42LLYY1010 pKa = 10.28FISDD1014 pKa = 4.19GEE1016 pKa = 4.25PTNNHH1021 pKa = 6.45SIANGNLTYY1030 pKa = 10.72NGYY1033 pKa = 10.47EE1034 pKa = 4.0DD1035 pKa = 3.83TEE1037 pKa = 4.02AWEE1040 pKa = 4.04QFITDD1045 pKa = 3.63SSIDD1049 pKa = 3.23KK1050 pKa = 10.75AFAVGFAGARR1060 pKa = 11.84SSALEE1065 pKa = 3.71PVAYY1069 pKa = 9.66PNGEE1073 pKa = 4.23DD1074 pKa = 3.34GGEE1077 pKa = 4.05VIIIDD1082 pKa = 4.18SASDD1086 pKa = 3.43LADD1089 pKa = 3.54ALINSLVDD1097 pKa = 3.3HH1098 pKa = 6.26VQTGTVINTEE1108 pKa = 3.95NASAEE1113 pKa = 4.1GFIIGADD1120 pKa = 3.53DD1121 pKa = 4.41AGSHH1125 pKa = 5.97IQSIMINHH1133 pKa = 5.59VVYY1136 pKa = 10.09EE1137 pKa = 4.34FNPAEE1142 pKa = 4.09PEE1144 pKa = 3.89IEE1146 pKa = 4.1VATGIKK1152 pKa = 10.31GATLTFNFLTGTYY1165 pKa = 10.02QYY1167 pKa = 10.44TVDD1170 pKa = 3.82SNEE1173 pKa = 4.04EE1174 pKa = 3.72IIAAEE1179 pKa = 4.2TFPITLVDD1187 pKa = 3.51GDD1189 pKa = 4.1GDD1191 pKa = 3.72EE1192 pKa = 4.4KK1193 pKa = 10.62TIHH1196 pKa = 6.26LTVQVNYY1203 pKa = 9.15EE1204 pKa = 3.82ASIDD1208 pKa = 3.84ANRR1211 pKa = 11.84DD1212 pKa = 3.69TIITNLTEE1220 pKa = 4.11GSLNFDD1226 pKa = 4.37ASALLNNDD1234 pKa = 3.19AGITNDD1240 pKa = 3.49VLISQVNNPKK1250 pKa = 10.68GGTVSLNNNMIQFNLNAQYY1269 pKa = 10.9SANDD1273 pKa = 3.58FNNTQYY1279 pKa = 11.88AKK1281 pKa = 10.17IVNEE1285 pKa = 4.19SEE1287 pKa = 4.18NNNTKK1292 pKa = 10.76LNADD1296 pKa = 4.03EE1297 pKa = 4.41ISRR1300 pKa = 11.84GSFKK1304 pKa = 11.27SNGLNNYY1311 pKa = 9.68SMTYY1315 pKa = 9.95RR1316 pKa = 11.84GAVSSNDD1323 pKa = 3.34ADD1325 pKa = 3.19WFMLSLAAGEE1335 pKa = 4.46LVHH1338 pKa = 7.67IDD1340 pKa = 4.47LNNTAYY1346 pKa = 10.95NIDD1349 pKa = 3.19IFAYY1353 pKa = 10.26DD1354 pKa = 3.75DD1355 pKa = 3.91NGNQLTQIFDD1365 pKa = 3.88YY1366 pKa = 10.48TFSSYY1371 pKa = 11.22YY1372 pKa = 8.26GTYY1375 pKa = 10.66GITNGLFAVQEE1386 pKa = 3.9EE1387 pKa = 4.77GNYY1390 pKa = 9.49YY1391 pKa = 10.25FQVAKK1396 pKa = 10.96NSGSSLNYY1404 pKa = 8.84EE1405 pKa = 4.08ANITIDD1411 pKa = 3.44TSNAQYY1417 pKa = 10.83QGFDD1421 pKa = 3.44YY1422 pKa = 10.74TVNDD1426 pKa = 3.83HH1427 pKa = 6.32NAVEE1431 pKa = 4.53ISAPVNIIVQEE1442 pKa = 4.18GNEE1445 pKa = 4.15LTGSEE1450 pKa = 4.21ASEE1453 pKa = 3.78ILIGSDD1459 pKa = 3.24GDD1461 pKa = 4.37DD1462 pKa = 4.3MINADD1467 pKa = 4.36GGDD1470 pKa = 3.66DD1471 pKa = 3.7VLFAGLGDD1479 pKa = 5.38DD1480 pKa = 4.26ILHH1483 pKa = 6.64GGDD1486 pKa = 4.33GNDD1489 pKa = 3.32TLFGGEE1495 pKa = 4.77GNDD1498 pKa = 3.47TMTGGDD1504 pKa = 3.77GQNTFVWKK1512 pKa = 10.68AGDD1515 pKa = 3.76DD1516 pKa = 3.66AGGSIDD1522 pKa = 4.34TITDD1526 pKa = 4.24FKK1528 pKa = 11.02LGQNGDD1534 pKa = 3.88VLDD1537 pKa = 5.03LSDD1540 pKa = 4.92LLVGEE1545 pKa = 4.78SNTAEE1550 pKa = 4.25SLDD1553 pKa = 3.59AYY1555 pKa = 11.39LNISYY1560 pKa = 10.89DD1561 pKa = 3.61NASNTSTVSVNPDD1574 pKa = 2.68GSASFSATQAIVLSGVDD1591 pKa = 3.59LTAGGTLQTDD1601 pKa = 3.55QAILDD1606 pKa = 3.75VLINNGNIVTDD1617 pKa = 4.25GGG1619 pKa = 3.73

Molecular weight:
172.22 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A0W0VT33|A0A0W0VT33_9GAMM 3-hydroxymyristoyl-ACP dehydratase OS=Legionella londiniensis OX=45068 GN=fabA PE=4 SV=1
MM1 pKa = 7.55ALIKK5 pKa = 10.53SKK7 pKa = 9.07PTSPGKK13 pKa = 10.09RR14 pKa = 11.84GEE16 pKa = 3.61IRR18 pKa = 11.84VRR20 pKa = 11.84HH21 pKa = 5.9DD22 pKa = 3.38VYY24 pKa = 11.16KK25 pKa = 10.86GDD27 pKa = 4.54PFPGLISTVKK37 pKa = 9.51KK38 pKa = 9.15TGGRR42 pKa = 11.84NNQGRR47 pKa = 11.84ITVRR51 pKa = 11.84HH52 pKa = 5.83IGGGTRR58 pKa = 11.84VQYY61 pKa = 10.79RR62 pKa = 11.84HH63 pKa = 6.6IDD65 pKa = 3.68FKK67 pKa = 11.19RR68 pKa = 11.84NKK70 pKa = 9.81DD71 pKa = 3.49GIEE74 pKa = 3.79ARR76 pKa = 11.84VEE78 pKa = 4.11RR79 pKa = 11.84IEE81 pKa = 3.97YY82 pKa = 10.37DD83 pKa = 3.49PNRR86 pKa = 11.84SALIALIVYY95 pKa = 10.06KK96 pKa = 10.6DD97 pKa = 3.22GEE99 pKa = 4.23RR100 pKa = 11.84RR101 pKa = 11.84YY102 pKa = 10.08IIAPAGLALNDD113 pKa = 4.01TVVSGDD119 pKa = 4.09DD120 pKa = 3.7APISTGNALPLKK132 pKa = 8.99NIPVGTTVHH141 pKa = 6.24CVEE144 pKa = 5.21LKK146 pKa = 10.19PGCGAQLLRR155 pKa = 11.84SAGCSGQIVAKK166 pKa = 9.68EE167 pKa = 3.95GAYY170 pKa = 8.78STLKK174 pKa = 10.45LRR176 pKa = 11.84SGEE179 pKa = 3.95MRR181 pKa = 11.84KK182 pKa = 9.5VLSACRR188 pKa = 11.84ATVGEE193 pKa = 4.46VSNSEE198 pKa = 4.06HH199 pKa = 6.74NLRR202 pKa = 11.84ALGKK206 pKa = 10.04AGASRR211 pKa = 11.84WRR213 pKa = 11.84GKK215 pKa = 10.27RR216 pKa = 11.84PTVRR220 pKa = 11.84GVAMNPVDD228 pKa = 3.85HH229 pKa = 6.82PHH231 pKa = 6.77GGGEE235 pKa = 4.38GKK237 pKa = 9.02TSGGRR242 pKa = 11.84HH243 pKa = 5.83PVTPWGIPTKK253 pKa = 10.33GYY255 pKa = 7.47KK256 pKa = 7.77TRR258 pKa = 11.84RR259 pKa = 11.84NKK261 pKa = 9.32RR262 pKa = 11.84TSKK265 pKa = 10.29YY266 pKa = 9.53IVRR269 pKa = 11.84GRR271 pKa = 11.84KK272 pKa = 8.88NKK274 pKa = 10.12

Molecular weight:
29.71 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2172

0

2172

722513

51

3879

332.6

37.38

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.372 ± 0.056

1.188 ± 0.018

4.7 ± 0.04

6.336 ± 0.054

4.471 ± 0.038

6.208 ± 0.044

2.595 ± 0.026

7.254 ± 0.047

6.19 ± 0.058

11.267 ± 0.058

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.396 ± 0.021

4.372 ± 0.041

4.137 ± 0.034

4.593 ± 0.04

4.794 ± 0.039

6.081 ± 0.031

4.715 ± 0.033

5.787 ± 0.048

1.143 ± 0.02

3.393 ± 0.03

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski