Amino acid dipepetide frequency for Mastomys natalensis polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.867AlaAla: 5.867 ± 3.259
1.6AlaCys: 1.6 ± 1.933
1.6AlaAsp: 1.6 ± 0.873
5.333AlaGlu: 5.333 ± 2.842
3.2AlaPhe: 3.2 ± 0.753
3.2AlaGly: 3.2 ± 0.657
1.067AlaHis: 1.067 ± 0.767
1.6AlaIle: 1.6 ± 0.699
3.2AlaLys: 3.2 ± 1.043
8.533AlaLeu: 8.533 ± 2.159
0.533AlaMet: 0.533 ± 0.38
4.267AlaAsn: 4.267 ± 1.221
1.067AlaPro: 1.067 ± 0.467
3.2AlaGln: 3.2 ± 0.657
7.467AlaArg: 7.467 ± 3.644
5.333AlaSer: 5.333 ± 2.881
2.133AlaThr: 2.133 ± 0.794
6.933AlaVal: 6.933 ± 1.138
0.533AlaTrp: 0.533 ± 0.38
0.533AlaTyr: 0.533 ± 0.51
0.0AlaXaa: 0.0 ± 0.0
Cys
0.533CysAla: 0.533 ± 0.714
0.0CysCys: 0.0 ± 0.0
2.133CysAsp: 2.133 ± 0.714
0.0CysGlu: 0.0 ± 0.0
0.533CysPhe: 0.533 ± 0.714
2.133CysGly: 2.133 ± 1.192
0.0CysHis: 0.0 ± 0.0
0.533CysIle: 0.533 ± 0.644
2.667CysLys: 2.667 ± 1.032
2.667CysLeu: 2.667 ± 2.538
0.533CysMet: 0.533 ± 0.38
2.133CysAsn: 2.133 ± 1.131
0.0CysPro: 0.0 ± 0.0
1.6CysGln: 1.6 ± 0.813
1.067CysArg: 1.067 ± 0.691
1.067CysSer: 1.067 ± 0.759
1.067CysThr: 1.067 ± 0.883
1.6CysVal: 1.6 ± 0.872
1.067CysTrp: 1.067 ± 0.691
1.067CysTyr: 1.067 ± 0.883
0.0CysXaa: 0.0 ± 0.0
Asp
0.533AspAla: 0.533 ± 0.38
1.6AspCys: 1.6 ± 0.872
1.067AspAsp: 1.067 ± 0.691
0.533AspGlu: 0.533 ± 0.38
1.067AspPhe: 1.067 ± 0.759
4.267AspGly: 4.267 ± 1.081
3.2AspHis: 3.2 ± 1.449
4.267AspIle: 4.267 ± 0.581
2.133AspLys: 2.133 ± 0.923
7.467AspLeu: 7.467 ± 2.224
2.667AspMet: 2.667 ± 0.91
2.133AspAsn: 2.133 ± 0.934
4.267AspPro: 4.267 ± 1.685
2.667AspGln: 2.667 ± 1.51
2.133AspArg: 2.133 ± 0.964
2.667AspSer: 2.667 ± 0.686
1.067AspThr: 1.067 ± 0.97
3.733AspVal: 3.733 ± 1.676
1.6AspTrp: 1.6 ± 0.939
2.667AspTyr: 2.667 ± 0.535
0.0AspXaa: 0.0 ± 0.0
Glu
6.4GluAla: 6.4 ± 2.064
1.067GluCys: 1.067 ± 0.628
3.733GluAsp: 3.733 ± 1.068
13.867GluGlu: 13.867 ± 2.801
2.667GluPhe: 2.667 ± 1.021
3.733GluGly: 3.733 ± 2.2
2.667GluHis: 2.667 ± 1.814
2.667GluIle: 2.667 ± 0.968
3.733GluLys: 3.733 ± 1.174
7.467GluLeu: 7.467 ± 1.766
1.067GluMet: 1.067 ± 0.467
3.2GluAsn: 3.2 ± 1.172
1.6GluPro: 1.6 ± 0.675
2.133GluGln: 2.133 ± 0.923
3.2GluArg: 3.2 ± 0.81
2.667GluSer: 2.667 ± 0.95
4.8GluThr: 4.8 ± 2.068
4.8GluVal: 4.8 ± 2.719
0.533GluTrp: 0.533 ± 0.38
2.667GluTyr: 2.667 ± 0.535
0.0GluXaa: 0.0 ± 0.0
Phe
1.6PheAla: 1.6 ± 0.699
2.133PheCys: 2.133 ± 1.382
1.6PheAsp: 1.6 ± 1.139
3.2PheGlu: 3.2 ± 1.158
1.6PhePhe: 1.6 ± 0.699
1.067PheGly: 1.067 ± 0.883
0.533PheHis: 0.533 ± 0.485
0.533PheIle: 0.533 ± 0.38
1.067PheLys: 1.067 ± 0.978
4.8PheLeu: 4.8 ± 1.557
1.067PheMet: 1.067 ± 0.685
1.067PheAsn: 1.067 ± 0.467
5.333PhePro: 5.333 ± 1.213
0.533PheGln: 0.533 ± 0.38
1.067PheArg: 1.067 ± 0.97
4.8PheSer: 4.8 ± 1.116
2.133PheThr: 2.133 ± 0.616
3.733PheVal: 3.733 ± 1.412
1.067PheTrp: 1.067 ± 0.767
0.533PheTyr: 0.533 ± 0.644
0.0PheXaa: 0.0 ± 0.0
Gly
5.333GlyAla: 5.333 ± 1.845
0.0GlyCys: 0.0 ± 0.0
5.333GlyAsp: 5.333 ± 1.657
5.333GlyGlu: 5.333 ± 2.87
2.133GlyPhe: 2.133 ± 1.333
4.8GlyGly: 4.8 ± 0.936
0.533GlyHis: 0.533 ± 0.644
5.867GlyIle: 5.867 ± 2.13
5.333GlyLys: 5.333 ± 1.711
8.0GlyLeu: 8.0 ± 2.176
0.0GlyMet: 0.0 ± 0.0
1.6GlyAsn: 1.6 ± 1.353
3.733GlyPro: 3.733 ± 1.619
3.2GlyGln: 3.2 ± 1.409
1.6GlyArg: 1.6 ± 0.675
1.067GlySer: 1.067 ± 0.642
2.133GlyThr: 2.133 ± 1.192
2.667GlyVal: 2.667 ± 1.127
1.6GlyTrp: 1.6 ± 0.998
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.133HisAla: 2.133 ± 0.836
0.533HisCys: 0.533 ± 0.644
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.533HisPhe: 0.533 ± 0.485
0.0HisGly: 0.0 ± 0.0
1.067HisHis: 1.067 ± 0.759
0.533HisIle: 0.533 ± 0.51
1.6HisLys: 1.6 ± 0.813
2.667HisLeu: 2.667 ± 1.109
1.067HisMet: 1.067 ± 0.648
1.067HisAsn: 1.067 ± 1.428
1.067HisPro: 1.067 ± 0.691
1.067HisGln: 1.067 ± 0.767
1.067HisArg: 1.067 ± 0.759
1.067HisSer: 1.067 ± 0.766
2.667HisThr: 2.667 ± 0.667
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.533HisTyr: 0.533 ± 0.38
0.0HisXaa: 0.0 ± 0.0
Ile
1.6IleAla: 1.6 ± 0.742
1.067IleCys: 1.067 ± 0.467
2.133IleAsp: 2.133 ± 0.54
2.667IleGlu: 2.667 ± 1.411
1.6IlePhe: 1.6 ± 0.857
1.067IleGly: 1.067 ± 0.767
0.0IleHis: 0.0 ± 0.0
1.6IleIle: 1.6 ± 0.501
3.2IleLys: 3.2 ± 0.513
4.8IleLeu: 4.8 ± 0.764
1.067IleMet: 1.067 ± 0.858
3.733IleAsn: 3.733 ± 1.258
2.667IlePro: 2.667 ± 1.377
1.067IleGln: 1.067 ± 0.766
1.067IleArg: 1.067 ± 0.767
4.8IleSer: 4.8 ± 0.671
6.4IleThr: 6.4 ± 1.437
1.6IleVal: 1.6 ± 0.766
0.0IleTrp: 0.0 ± 0.0
0.533IleTyr: 0.533 ± 0.38
0.0IleXaa: 0.0 ± 0.0
Lys
4.8LysAla: 4.8 ± 2.135
2.667LysCys: 2.667 ± 2.133
3.2LysAsp: 3.2 ± 1.798
5.867LysGlu: 5.867 ± 1.344
1.6LysPhe: 1.6 ± 0.766
4.8LysGly: 4.8 ± 1.716
1.6LysHis: 1.6 ± 0.813
2.133LysIle: 2.133 ± 0.714
7.467LysLys: 7.467 ± 3.353
6.933LysLeu: 6.933 ± 0.993
1.6LysMet: 1.6 ± 0.873
2.667LysAsn: 2.667 ± 1.313
1.6LysPro: 1.6 ± 0.699
1.067LysGln: 1.067 ± 1.288
4.8LysArg: 4.8 ± 1.121
2.133LysSer: 2.133 ± 0.782
4.8LysThr: 4.8 ± 1.869
2.667LysVal: 2.667 ± 1.823
0.533LysTrp: 0.533 ± 0.38
2.133LysTyr: 2.133 ± 0.54
0.0LysXaa: 0.0 ± 0.0
Leu
13.867LeuAla: 13.867 ± 4.781
2.667LeuCys: 2.667 ± 1.032
4.267LeuAsp: 4.267 ± 1.838
6.4LeuGlu: 6.4 ± 1.459
3.2LeuPhe: 3.2 ± 1.318
5.867LeuGly: 5.867 ± 1.961
1.6LeuHis: 1.6 ± 0.857
3.733LeuIle: 3.733 ± 0.608
3.2LeuLys: 3.2 ± 1.261
10.133LeuLeu: 10.133 ± 1.323
5.333LeuMet: 5.333 ± 2.169
9.067LeuAsn: 9.067 ± 1.401
10.133LeuPro: 10.133 ± 1.399
6.4LeuGln: 6.4 ± 0.961
5.333LeuArg: 5.333 ± 1.359
6.4LeuSer: 6.4 ± 0.895
5.333LeuThr: 5.333 ± 1.029
2.667LeuVal: 2.667 ± 0.824
1.6LeuTrp: 1.6 ± 0.998
6.933LeuTyr: 6.933 ± 1.764
0.0LeuXaa: 0.0 ± 0.0
Met
2.133MetAla: 2.133 ± 0.54
1.067MetCys: 1.067 ± 0.628
2.667MetAsp: 2.667 ± 1.109
3.2MetGlu: 3.2 ± 1.449
0.533MetPhe: 0.533 ± 0.38
1.6MetGly: 1.6 ± 0.501
0.0MetHis: 0.0 ± 0.0
0.533MetIle: 0.533 ± 0.644
1.067MetLys: 1.067 ± 0.691
2.667MetLeu: 2.667 ± 0.535
1.067MetMet: 1.067 ± 0.698
0.0MetAsn: 0.0 ± 0.0
1.067MetPro: 1.067 ± 0.883
1.6MetGln: 1.6 ± 1.455
1.6MetArg: 1.6 ± 0.872
0.533MetSer: 0.533 ± 0.38
0.533MetThr: 0.533 ± 0.38
1.067MetVal: 1.067 ± 0.467
0.533MetTrp: 0.533 ± 0.485
1.067MetTyr: 1.067 ± 0.628
0.0MetXaa: 0.0 ± 0.0
Asn
2.133AsnAla: 2.133 ± 0.782
1.067AsnCys: 1.067 ± 0.691
1.067AsnAsp: 1.067 ± 0.467
4.267AsnGlu: 4.267 ± 1.801
4.8AsnPhe: 4.8 ± 0.785
0.533AsnGly: 0.533 ± 0.485
1.6AsnHis: 1.6 ± 0.675
2.133AsnIle: 2.133 ± 0.825
3.2AsnLys: 3.2 ± 1.031
8.533AsnLeu: 8.533 ± 2.145
1.6AsnMet: 1.6 ± 0.488
1.067AsnAsn: 1.067 ± 0.467
2.133AsnPro: 2.133 ± 1.026
3.733AsnGln: 3.733 ± 0.948
0.0AsnArg: 0.0 ± 0.0
1.6AsnSer: 1.6 ± 0.699
2.667AsnThr: 2.667 ± 1.313
1.6AsnVal: 1.6 ± 0.873
0.533AsnTrp: 0.533 ± 0.714
3.2AsnTyr: 3.2 ± 0.548
0.0AsnXaa: 0.0 ± 0.0
Pro
2.667ProAla: 2.667 ± 0.773
0.533ProCys: 0.533 ± 0.485
5.867ProAsp: 5.867 ± 1.502
1.6ProGlu: 1.6 ± 0.636
2.133ProPhe: 2.133 ± 0.758
5.333ProGly: 5.333 ± 0.796
0.0ProHis: 0.0 ± 0.0
2.667ProIle: 2.667 ± 0.773
5.867ProLys: 5.867 ± 1.322
4.8ProLeu: 4.8 ± 1.27
1.6ProMet: 1.6 ± 0.766
0.533ProAsn: 0.533 ± 0.51
2.133ProPro: 2.133 ± 1.024
4.8ProGln: 4.8 ± 1.557
2.133ProArg: 2.133 ± 1.026
3.733ProSer: 3.733 ± 1.123
0.533ProThr: 0.533 ± 0.38
3.2ProVal: 3.2 ± 1.401
0.0ProTrp: 0.0 ± 0.0
2.667ProTyr: 2.667 ± 0.882
0.0ProXaa: 0.0 ± 0.0
Gln
1.6GlnAla: 1.6 ± 1.139
0.533GlnCys: 0.533 ± 0.714
2.133GlnAsp: 2.133 ± 0.94
3.2GlnGlu: 3.2 ± 0.976
1.6GlnPhe: 1.6 ± 0.873
2.667GlnGly: 2.667 ± 1.354
0.0GlnHis: 0.0 ± 0.0
3.2GlnIle: 3.2 ± 0.657
3.733GlnLys: 3.733 ± 1.309
7.467GlnLeu: 7.467 ± 0.797
0.0GlnMet: 0.0 ± 0.0
1.067GlnAsn: 1.067 ± 0.75
0.533GlnPro: 0.533 ± 0.38
1.6GlnGln: 1.6 ± 0.813
1.6GlnArg: 1.6 ± 0.675
4.8GlnSer: 4.8 ± 1.386
4.8GlnThr: 4.8 ± 1.042
3.2GlnVal: 3.2 ± 1.692
0.0GlnTrp: 0.0 ± 0.0
2.133GlnTyr: 2.133 ± 1.131
0.0GlnXaa: 0.0 ± 0.0
Arg
1.067ArgAla: 1.067 ± 0.767
1.6ArgCys: 1.6 ± 0.766
2.133ArgAsp: 2.133 ± 0.758
3.733ArgGlu: 3.733 ± 0.556
3.733ArgPhe: 3.733 ± 0.876
1.067ArgGly: 1.067 ± 0.883
2.133ArgHis: 2.133 ± 0.782
1.067ArgIle: 1.067 ± 0.759
5.333ArgLys: 5.333 ± 1.141
2.133ArgLeu: 2.133 ± 1.079
0.533ArgMet: 0.533 ± 0.485
2.667ArgAsn: 2.667 ± 0.831
2.667ArgPro: 2.667 ± 0.667
2.667ArgGln: 2.667 ± 1.659
0.533ArgArg: 0.533 ± 0.38
1.6ArgSer: 1.6 ± 0.998
2.133ArgThr: 2.133 ± 1.026
3.733ArgVal: 3.733 ± 1.208
2.133ArgTrp: 2.133 ± 1.534
6.4ArgTyr: 6.4 ± 2.688
0.0ArgXaa: 0.0 ± 0.0
Ser
4.8SerAla: 4.8 ± 1.188
0.0SerCys: 0.0 ± 0.0
2.667SerAsp: 2.667 ± 0.535
2.133SerGlu: 2.133 ± 0.657
0.533SerPhe: 0.533 ± 0.38
3.733SerGly: 3.733 ± 0.878
1.067SerHis: 1.067 ± 0.818
2.667SerIle: 2.667 ± 0.99
2.133SerLys: 2.133 ± 0.964
5.333SerLeu: 5.333 ± 0.923
0.0SerMet: 0.0 ± 0.0
3.2SerAsn: 3.2 ± 0.755
4.8SerPro: 4.8 ± 1.847
2.667SerGln: 2.667 ± 1.377
4.8SerArg: 4.8 ± 2.026
0.533SerSer: 0.533 ± 0.485
4.267SerThr: 4.267 ± 1.028
3.733SerVal: 3.733 ± 1.054
1.6SerTrp: 1.6 ± 0.939
1.067SerTyr: 1.067 ± 0.642
0.0SerXaa: 0.0 ± 0.0
Thr
3.733ThrAla: 3.733 ± 0.976
1.6ThrCys: 1.6 ± 0.766
2.133ThrAsp: 2.133 ± 0.897
4.8ThrGlu: 4.8 ± 1.41
0.533ThrPhe: 0.533 ± 0.38
3.2ThrGly: 3.2 ± 1.003
0.0ThrHis: 0.0 ± 0.0
4.267ThrIle: 4.267 ± 1.003
1.6ThrLys: 1.6 ± 0.765
10.133ThrLeu: 10.133 ± 1.957
0.533ThrMet: 0.533 ± 0.38
3.2ThrAsn: 3.2 ± 1.172
5.333ThrPro: 5.333 ± 1.532
3.733ThrGln: 3.733 ± 1.023
2.133ThrArg: 2.133 ± 0.825
0.533ThrSer: 0.533 ± 0.38
3.733ThrThr: 3.733 ± 0.832
4.267ThrVal: 4.267 ± 1.424
1.067ThrTrp: 1.067 ± 0.691
3.2ThrTyr: 3.2 ± 0.794
0.0ThrXaa: 0.0 ± 0.0
Val
3.2ValAla: 3.2 ± 1.225
1.6ValCys: 1.6 ± 0.857
3.733ValAsp: 3.733 ± 0.647
4.8ValGlu: 4.8 ± 1.054
2.133ValPhe: 2.133 ± 0.794
5.333ValGly: 5.333 ± 2.22
0.533ValHis: 0.533 ± 0.485
1.067ValIle: 1.067 ± 0.759
3.733ValLys: 3.733 ± 1.3
5.867ValLeu: 5.867 ± 1.639
1.067ValMet: 1.067 ± 0.766
2.667ValAsn: 2.667 ± 1.028
1.067ValPro: 1.067 ± 0.766
0.533ValGln: 0.533 ± 0.644
3.2ValArg: 3.2 ± 1.172
2.133ValSer: 2.133 ± 0.844
6.933ValThr: 6.933 ± 1.497
1.6ValVal: 1.6 ± 0.699
0.533ValTrp: 0.533 ± 0.485
2.133ValTyr: 2.133 ± 1.024
0.0ValXaa: 0.0 ± 0.0
Trp
2.133TrpAla: 2.133 ± 1.534
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.133TrpGlu: 2.133 ± 0.897
1.6TrpPhe: 1.6 ± 0.939
1.6TrpGly: 1.6 ± 0.939
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.6TrpLys: 1.6 ± 0.675
1.067TrpLeu: 1.067 ± 0.691
1.067TrpMet: 1.067 ± 0.767
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.6TrpGln: 1.6 ± 0.998
1.067TrpArg: 1.067 ± 0.691
0.533TrpSer: 0.533 ± 0.485
0.533TrpThr: 0.533 ± 0.38
0.0TrpVal: 0.0 ± 0.0
0.533TrpTrp: 0.533 ± 0.38
0.533TrpTyr: 0.533 ± 0.38
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.067TyrAla: 1.067 ± 0.759
1.067TyrCys: 1.067 ± 0.759
4.267TyrAsp: 4.267 ± 2.053
1.6TyrGlu: 1.6 ± 1.017
3.733TyrPhe: 3.733 ± 1.617
4.267TyrGly: 4.267 ± 0.704
1.067TyrHis: 1.067 ± 0.767
2.133TyrIle: 2.133 ± 0.956
3.2TyrLys: 3.2 ± 1.787
2.667TyrLeu: 2.667 ± 1.377
1.6TyrMet: 1.6 ± 0.813
2.133TyrAsn: 2.133 ± 0.782
1.6TyrPro: 1.6 ± 1.017
0.0TyrGln: 0.0 ± 0.0
3.2TyrArg: 3.2 ± 0.513
3.733TyrSer: 3.733 ± 2.191
1.067TyrThr: 1.067 ± 0.467
1.067TyrVal: 1.067 ± 0.767
0.533TyrTrp: 0.533 ± 0.38
2.667TyrTyr: 2.667 ± 0.686
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1876 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski