Amino acid dipepetide frequency for Colletotrichum orchidophilum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.519AlaAla: 10.519 ± 0.069	1.122AlaCys: 1.122 ± 0.015	4.564AlaAsp: 4.564 ± 0.029	5.305AlaGlu: 5.305 ± 0.048	3.241AlaPhe: 3.241 ± 0.027	6.305AlaGly: 6.305 ± 0.037	1.797AlaHis: 1.797 ± 0.02	4.266AlaIle: 4.266 ± 0.028	4.275AlaLys: 4.275 ± 0.035	7.774AlaLeu: 7.774 ± 0.039	2.042AlaMet: 2.042 ± 0.018	3.088AlaAsn: 3.088 ± 0.025	5.214AlaPro: 5.214 ± 0.043	3.477AlaGln: 3.477 ± 0.028	4.981AlaArg: 4.981 ± 0.032	7.608AlaSer: 7.608 ± 0.041	5.627AlaThr: 5.627 ± 0.038	5.832AlaVal: 5.832 ± 0.029	1.263AlaTrp: 1.263 ± 0.017	2.165AlaTyr: 2.165 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.964CysAla: 0.964 ± 0.013	0.269CysCys: 0.269 ± 0.008	0.665CysAsp: 0.665 ± 0.011	0.586CysGlu: 0.586 ± 0.01	0.54CysPhe: 0.54 ± 0.009	0.996CysGly: 0.996 ± 0.016	0.342CysHis: 0.342 ± 0.007	0.683CysIle: 0.683 ± 0.012	0.512CysLys: 0.512 ± 0.01	1.241CysLeu: 1.241 ± 0.016	0.264CysMet: 0.264 ± 0.006	0.451CysAsn: 0.451 ± 0.009	0.699CysPro: 0.699 ± 0.013	0.463CysGln: 0.463 ± 0.009	0.789CysArg: 0.789 ± 0.011	0.939CysSer: 0.939 ± 0.013	0.698CysThr: 0.698 ± 0.01	0.821CysVal: 0.821 ± 0.011	0.222CysTrp: 0.222 ± 0.006	0.342CysTyr: 0.342 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.996AspAla: 4.996 ± 0.031	0.646AspCys: 0.646 ± 0.011	4.438AspAsp: 4.438 ± 0.039	4.425AspGlu: 4.425 ± 0.038	2.303AspPhe: 2.303 ± 0.022	4.337AspGly: 4.337 ± 0.028	1.221AspHis: 1.221 ± 0.015	2.886AspIle: 2.886 ± 0.024	2.413AspLys: 2.413 ± 0.023	4.939AspLeu: 4.939 ± 0.028	1.267AspMet: 1.267 ± 0.014	1.867AspAsn: 1.867 ± 0.018	3.214AspPro: 3.214 ± 0.023	1.808AspGln: 1.808 ± 0.019	2.987AspArg: 2.987 ± 0.026	3.904AspSer: 3.904 ± 0.027	2.84AspThr: 2.84 ± 0.026	3.814AspVal: 3.814 ± 0.027	0.925AspTrp: 0.925 ± 0.01	1.548AspTyr: 1.548 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.596GluAla: 5.596 ± 0.036	0.596GluCys: 0.596 ± 0.01	4.125GluAsp: 4.125 ± 0.037	5.285GluGlu: 5.285 ± 0.059	1.893GluPhe: 1.893 ± 0.018	3.727GluGly: 3.727 ± 0.024	1.319GluHis: 1.319 ± 0.014	2.879GluIle: 2.879 ± 0.024	3.633GluLys: 3.633 ± 0.033	4.868GluLeu: 4.868 ± 0.034	1.443GluMet: 1.443 ± 0.015	2.17GluAsn: 2.17 ± 0.02	2.829GluPro: 2.829 ± 0.038	2.274GluGln: 2.274 ± 0.022	3.729GluArg: 3.729 ± 0.035	4.107GluSer: 4.107 ± 0.028	3.542GluThr: 3.542 ± 0.029	3.617GluVal: 3.617 ± 0.025	0.872GluTrp: 0.872 ± 0.014	1.555GluTyr: 1.555 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.178PheAla: 3.178 ± 0.023	0.58PheCys: 0.58 ± 0.011	2.302PheAsp: 2.302 ± 0.023	2.113PheGlu: 2.113 ± 0.02	1.697PhePhe: 1.697 ± 0.018	2.944PheGly: 2.944 ± 0.027	0.904PheHis: 0.904 ± 0.012	1.826PheIle: 1.826 ± 0.02	1.571PheLys: 1.571 ± 0.017	3.424PheLeu: 3.424 ± 0.028	0.787PheMet: 0.787 ± 0.012	1.482PheAsn: 1.482 ± 0.019	1.988PhePro: 1.988 ± 0.02	1.38PheGln: 1.38 ± 0.015	1.962PheArg: 1.962 ± 0.019	3.024PheSer: 3.024 ± 0.022	2.189PheThr: 2.189 ± 0.024	2.426PheVal: 2.426 ± 0.023	0.665PheTrp: 0.665 ± 0.012	1.105PheTyr: 1.105 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.795GlyAla: 5.795 ± 0.036	0.929GlyCys: 0.929 ± 0.013	3.761GlyAsp: 3.761 ± 0.031	3.576GlyGlu: 3.576 ± 0.026	2.932GlyPhe: 2.932 ± 0.022	6.573GlyGly: 6.573 ± 0.054	1.74GlyHis: 1.74 ± 0.019	3.542GlyIle: 3.542 ± 0.027	3.423GlyLys: 3.423 ± 0.024	6.199GlyLeu: 6.199 ± 0.033	1.638GlyMet: 1.638 ± 0.018	2.672GlyAsn: 2.672 ± 0.026	3.553GlyPro: 3.553 ± 0.027	2.614GlyGln: 2.614 ± 0.026	4.261GlyArg: 4.261 ± 0.032	5.879GlySer: 5.879 ± 0.04	4.189GlyThr: 4.189 ± 0.052	4.504GlyVal: 4.504 ± 0.032	1.215GlyTrp: 1.215 ± 0.014	2.083GlyTyr: 2.083 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.843HisAla: 1.843 ± 0.018	0.35HisCys: 0.35 ± 0.008	1.268HisAsp: 1.268 ± 0.014	1.279HisGlu: 1.279 ± 0.016	0.934HisPhe: 0.934 ± 0.013	1.733HisGly: 1.733 ± 0.018	0.902HisHis: 0.902 ± 0.015	1.134HisIle: 1.134 ± 0.014	0.88HisLys: 0.88 ± 0.013	2.199HisLeu: 2.199 ± 0.021	0.507HisMet: 0.507 ± 0.008	0.849HisAsn: 0.849 ± 0.013	1.645HisPro: 1.645 ± 0.018	1.031HisGln: 1.031 ± 0.016	1.539HisArg: 1.539 ± 0.017	1.744HisSer: 1.744 ± 0.021	1.229HisThr: 1.229 ± 0.015	1.448HisVal: 1.448 ± 0.015	0.348HisTrp: 0.348 ± 0.007	0.658HisTyr: 0.658 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.174IleAla: 4.174 ± 0.03	0.709IleCys: 0.709 ± 0.012	2.784IleAsp: 2.784 ± 0.022	2.768IleGlu: 2.768 ± 0.026	1.965IlePhe: 1.965 ± 0.019	3.194IleGly: 3.194 ± 0.03	1.158IleHis: 1.158 ± 0.015	2.52IleIle: 2.52 ± 0.027	2.206IleLys: 2.206 ± 0.019	4.338IleLeu: 4.338 ± 0.031	1.035IleMet: 1.035 ± 0.014	1.736IleAsn: 1.736 ± 0.019	2.974IlePro: 2.974 ± 0.023	1.773IleGln: 1.773 ± 0.018	2.703IleArg: 2.703 ± 0.024	3.653IleSer: 3.653 ± 0.027	2.801IleThr: 2.801 ± 0.027	3.186IleVal: 3.186 ± 0.027	0.732IleTrp: 0.732 ± 0.01	1.303IleTyr: 1.303 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.405LysAla: 4.405 ± 0.034	0.498LysCys: 0.498 ± 0.011	2.791LysAsp: 2.791 ± 0.025	3.247LysGlu: 3.247 ± 0.03	1.49LysPhe: 1.49 ± 0.016	2.983LysGly: 2.983 ± 0.027	1.098LysHis: 1.098 ± 0.014	2.248LysIle: 2.248 ± 0.019	3.388LysLys: 3.388 ± 0.047	4.012LysLeu: 4.012 ± 0.031	1.057LysMet: 1.057 ± 0.013	1.747LysAsn: 1.747 ± 0.017	2.752LysPro: 2.752 ± 0.027	1.772LysGln: 1.772 ± 0.021	3.253LysArg: 3.253 ± 0.031	3.486LysSer: 3.486 ± 0.027	2.965LysThr: 2.965 ± 0.021	2.831LysVal: 2.831 ± 0.022	0.69LysTrp: 0.69 ± 0.01	1.313LysTyr: 1.313 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.035LeuAla: 8.035 ± 0.04	1.182LeuCys: 1.182 ± 0.015	4.956LeuAsp: 4.956 ± 0.032	5.28LeuGlu: 5.28 ± 0.041	3.312LeuPhe: 3.312 ± 0.028	6.069LeuGly: 6.069 ± 0.039	2.117LeuHis: 2.117 ± 0.02	3.789LeuIle: 3.789 ± 0.029	4.047LeuLys: 4.047 ± 0.034	8.094LeuLeu: 8.094 ± 0.05	1.774LeuMet: 1.774 ± 0.019	3.035LeuAsn: 3.035 ± 0.022	5.526LeuPro: 5.526 ± 0.045	3.572LeuGln: 3.572 ± 0.027	5.597LeuArg: 5.597 ± 0.037	7.002LeuSer: 7.002 ± 0.043	4.853LeuThr: 4.853 ± 0.038	5.469LeuVal: 5.469 ± 0.034	1.231LeuTrp: 1.231 ± 0.015	2.226LeuTyr: 2.226 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.363MetAla: 2.363 ± 0.021	0.25MetCys: 0.25 ± 0.006	1.234MetAsp: 1.234 ± 0.014	1.246MetGlu: 1.246 ± 0.014	0.755MetPhe: 0.755 ± 0.012	1.493MetGly: 1.493 ± 0.017	0.454MetHis: 0.454 ± 0.008	0.98MetIle: 0.98 ± 0.014	1.022MetLys: 1.022 ± 0.015	1.822MetLeu: 1.822 ± 0.018	0.623MetMet: 0.623 ± 0.011	0.795MetAsn: 0.795 ± 0.012	1.322MetPro: 1.322 ± 0.017	0.822MetGln: 0.822 ± 0.012	1.32MetArg: 1.32 ± 0.014	1.888MetSer: 1.888 ± 0.017	1.343MetThr: 1.343 ± 0.014	1.302MetVal: 1.302 ± 0.015	0.268MetTrp: 0.268 ± 0.007	0.518MetTyr: 0.518 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.138AsnAla: 3.138 ± 0.023	0.454AsnCys: 0.454 ± 0.009	1.953AsnAsp: 1.953 ± 0.019	1.96AsnGlu: 1.96 ± 0.02	1.423AsnPhe: 1.423 ± 0.015	3.076AsnGly: 3.076 ± 0.031	0.833AsnHis: 0.833 ± 0.012	1.952AsnIle: 1.952 ± 0.022	1.592AsnLys: 1.592 ± 0.018	3.187AsnLeu: 3.187 ± 0.025	0.839AsnMet: 0.839 ± 0.013	1.521AsnAsn: 1.521 ± 0.019	2.431AsnPro: 2.431 ± 0.021	1.304AsnGln: 1.304 ± 0.017	1.895AsnArg: 1.895 ± 0.017	2.637AsnSer: 2.637 ± 0.026	2.176AsnThr: 2.176 ± 0.021	2.313AsnVal: 2.313 ± 0.021	0.563AsnTrp: 0.563 ± 0.009	1.048AsnTyr: 1.048 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.757ProAla: 5.757 ± 0.046	0.562ProCys: 0.562 ± 0.011	3.179ProAsp: 3.179 ± 0.024	3.799ProGlu: 3.799 ± 0.032	2.101ProPhe: 2.101 ± 0.02	4.135ProGly: 4.135 ± 0.033	1.3ProHis: 1.3 ± 0.016	2.541ProIle: 2.541 ± 0.022	2.705ProLys: 2.705 ± 0.024	4.714ProLeu: 4.714 ± 0.03	1.136ProMet: 1.136 ± 0.016	2.175ProAsn: 2.175 ± 0.02	5.451ProPro: 5.451 ± 0.071	2.475ProGln: 2.475 ± 0.029	3.593ProArg: 3.593 ± 0.031	5.914ProSer: 5.914 ± 0.049	4.143ProThr: 4.143 ± 0.036	3.705ProVal: 3.705 ± 0.033	0.813ProTrp: 0.813 ± 0.012	1.45ProTyr: 1.45 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.489GlnAla: 3.489 ± 0.028	0.454GlnCys: 0.454 ± 0.009	2.012GlnAsp: 2.012 ± 0.02	2.237GlnGlu: 2.237 ± 0.022	1.205GlnPhe: 1.205 ± 0.015	2.435GlnGly: 2.435 ± 0.022	1.108GlnHis: 1.108 ± 0.018	1.777GlnIle: 1.777 ± 0.016	1.884GlnLys: 1.884 ± 0.019	3.292GlnLeu: 3.292 ± 0.024	0.896GlnMet: 0.896 ± 0.014	1.474GlnAsn: 1.474 ± 0.015	2.555GlnPro: 2.555 ± 0.032	2.634GlnGln: 2.634 ± 0.06	2.623GlnArg: 2.623 ± 0.026	2.978GlnSer: 2.978 ± 0.025	2.346GlnThr: 2.346 ± 0.029	2.152GlnVal: 2.152 ± 0.019	0.573GlnTrp: 0.573 ± 0.008	1.085GlnTyr: 1.085 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	4.699ArgAla: 4.699 ± 0.027	0.747ArgCys: 0.747 ± 0.011	3.436ArgAsp: 3.436 ± 0.026	3.709ArgGlu: 3.709 ± 0.036	2.121ArgPhe: 2.121 ± 0.022	3.884ArgGly: 3.884 ± 0.034	1.599ArgHis: 1.599 ± 0.015	2.769ArgIle: 2.769 ± 0.018	3.342ArgLys: 3.342 ± 0.028	5.366ArgLeu: 5.366 ± 0.032	1.29ArgMet: 1.29 ± 0.015	2.216ArgAsn: 2.216 ± 0.022	3.685ArgPro: 3.685 ± 0.032	2.623ArgGln: 2.623 ± 0.028	5.183ArgArg: 5.183 ± 0.044	4.697ArgSer: 4.697 ± 0.038	3.237ArgThr: 3.237 ± 0.022	3.357ArgVal: 3.357 ± 0.022	0.97ArgTrp: 0.97 ± 0.014	1.59ArgTyr: 1.59 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.855SerAla: 6.855 ± 0.04	0.902SerCys: 0.902 ± 0.014	4.154SerAsp: 4.154 ± 0.029	3.939SerGlu: 3.939 ± 0.029	3.037SerPhe: 3.037 ± 0.024	5.685SerGly: 5.685 ± 0.038	1.905SerHis: 1.905 ± 0.02	3.806SerIle: 3.806 ± 0.025	3.649SerLys: 3.649 ± 0.025	7.016SerLeu: 7.016 ± 0.04	1.704SerMet: 1.704 ± 0.017	2.882SerAsn: 2.882 ± 0.025	5.509SerPro: 5.509 ± 0.046	3.209SerGln: 3.209 ± 0.029	4.967SerArg: 4.967 ± 0.044	8.626SerSer: 8.626 ± 0.078	5.478SerThr: 5.478 ± 0.043	4.64SerVal: 4.64 ± 0.033	1.159SerTrp: 1.159 ± 0.014	2.007SerTyr: 2.007 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.628ThrAla: 5.628 ± 0.035	0.773ThrCys: 0.773 ± 0.012	2.837ThrAsp: 2.837 ± 0.02	3.111ThrGlu: 3.111 ± 0.026	2.286ThrPhe: 2.286 ± 0.02	4.295ThrGly: 4.295 ± 0.046	1.259ThrHis: 1.259 ± 0.015	3.092ThrIle: 3.092 ± 0.034	2.642ThrLys: 2.642 ± 0.023	5.17ThrLeu: 5.17 ± 0.047	1.219ThrMet: 1.219 ± 0.015	2.167ThrAsn: 2.167 ± 0.02	4.461ThrPro: 4.461 ± 0.036	2.076ThrGln: 2.076 ± 0.019	3.16ThrArg: 3.16 ± 0.025	5.347ThrSer: 5.347 ± 0.046	4.588ThrThr: 4.588 ± 0.056	3.83ThrVal: 3.83 ± 0.047	0.917ThrTrp: 0.917 ± 0.012	1.625ThrTyr: 1.625 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.692ValAla: 5.692 ± 0.03	0.842ValCys: 0.842 ± 0.012	3.757ValAsp: 3.757 ± 0.025	3.885ValGlu: 3.885 ± 0.028	2.572ValPhe: 2.572 ± 0.021	4.162ValGly: 4.162 ± 0.029	1.36ValHis: 1.36 ± 0.016	2.968ValIle: 2.968 ± 0.027	2.915ValLys: 2.915 ± 0.025	5.619ValLeu: 5.619 ± 0.04	1.316ValMet: 1.316 ± 0.015	2.228ValAsn: 2.228 ± 0.018	3.726ValPro: 3.726 ± 0.033	2.271ValGln: 2.271 ± 0.02	3.463ValArg: 3.463 ± 0.024	4.666ValSer: 4.666 ± 0.028	3.718ValThr: 3.718 ± 0.038	4.515ValVal: 4.515 ± 0.036	0.933ValTrp: 0.933 ± 0.014	1.695ValTyr: 1.695 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.217TrpAla: 1.217 ± 0.016	0.211TrpCys: 0.211 ± 0.006	0.921TrpAsp: 0.921 ± 0.013	0.864TrpGlu: 0.864 ± 0.012	0.571TrpPhe: 0.571 ± 0.011	0.977TrpGly: 0.977 ± 0.015	0.376TrpHis: 0.376 ± 0.007	0.758TrpIle: 0.758 ± 0.012	0.809TrpLys: 0.809 ± 0.011	1.378TrpLeu: 1.378 ± 0.018	0.389TrpMet: 0.389 ± 0.008	0.654TrpAsn: 0.654 ± 0.01	0.68TrpPro: 0.68 ± 0.01	0.59TrpGln: 0.59 ± 0.01	0.971TrpArg: 0.971 ± 0.012	1.094TrpSer: 1.094 ± 0.015	0.983TrpThr: 0.983 ± 0.013	0.916TrpVal: 0.916 ± 0.012	0.297TrpTrp: 0.297 ± 0.007	0.446TrpTyr: 0.446 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.122TyrAla: 2.122 ± 0.02	0.41TyrCys: 0.41 ± 0.008	1.64TyrAsp: 1.64 ± 0.016	1.445TyrGlu: 1.445 ± 0.017	1.169TyrPhe: 1.169 ± 0.015	2.077TyrGly: 2.077 ± 0.023	0.733TyrHis: 0.733 ± 0.011	1.3TyrIle: 1.3 ± 0.015	1.117TyrLys: 1.117 ± 0.015	2.513TyrLeu: 2.513 ± 0.024	0.593TyrMet: 0.593 ± 0.01	1.085TyrAsn: 1.085 ± 0.016	1.434TyrPro: 1.434 ± 0.02	1.04TyrGln: 1.04 ± 0.013	1.545TyrArg: 1.545 ± 0.016	1.934TyrSer: 1.934 ± 0.02	1.541TyrThr: 1.541 ± 0.018	1.622TyrVal: 1.622 ± 0.018	0.444TyrTrp: 0.444 ± 0.009	0.89TyrTyr: 0.89 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14495 proteins (6380480 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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